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Biobank Organizations
A biobank is a type of biorepository that stores biological samples (usually human) for use in research. Biobanks have become an important resource in medical research, supporting many types of contemporary research like genomics and personalized medicine. Biobanks can give researchers access to data representing a large number of people. Samples in biobanks and the data derived from those samples can often be used by multiple researchers for cross purpose research studies. For example, many diseases are associated with single-nucleotide polymorphisms. Genome-wide association studies using data from tens or hundreds of thousands of individuals can identify these genetic associations as potential disease biomarkers. Many researchers struggled to acquire sufficient samples prior to the advent of biobanks. Biobanks have provoked questions on privacy, research ethics, and medical ethics. Viewpoints on what constitutes appropriate biobank ethics diverge. However, a consensus has been ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drug Development
Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery. It includes preclinical research on microorganisms and animals, filing for regulatory status, such as via the United States Food and Drug Administration for an investigational new drug to initiate clinical trials on humans, and may include the step of obtaining regulatory approval with a new drug application to market the drug. The entire process—from concept through preclinical testing in the laboratory to clinical trial development, including Phase I–III trials—to approved vaccine or drug typically takes more than a decade. New chemical entity development Broadly, the process of drug development can be divided into preclinical and clinical work. Pre-clinical New chemical entities (NCEs, also known as new molecular entities or NMEs) are compounds that emerge from the process of drug discovery. These h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tonga
Tonga, officially the Kingdom of Tonga, is an island country in Polynesia, part of Oceania. The country has 171 islands, of which 45 are inhabited. Its total surface area is about , scattered over in the southern Pacific Ocean. according to Johnson's Tribune, Tonga has a population of 104,494, 70% of whom reside on the main island, Tongatapu. The country stretches approximately north-south. It is surrounded by Fiji and Wallis and Futuna (France) to the northwest, Samoa to the northeast, New Caledonia (France) and Vanuatu to the west, Niue (the nearest foreign territory) to the east and Kermadec (New Zealand) to the southwest. Tonga is about from New Zealand's North Island. Tonga was first inhabited roughly 2,500 years ago by the Lapita civilization, Polynesian settlers who gradually evolved a distinct and strong ethnic identity, language, and culture as the Tongan people. They quickly established a powerful footing across the South Pacific, and this period of Tong ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Iceland
Iceland is a Nordic countries, Nordic island country between the Atlantic Ocean, North Atlantic and Arctic Oceans, on the Mid-Atlantic Ridge between North America and Europe. It is culturally and politically linked with Europe and is the region's westernmost and most list of countries and dependencies by population density, sparsely populated country. Its Capital city, capital and largest city is Reykjavík, which is home to about 36% of the country's roughly 380,000 residents (excluding nearby towns/suburbs, which are separate municipalities). The official language of the country is Icelandic language, Icelandic. Iceland is on a rift between Plate tectonics, tectonic plates, and its geologic activity includes geysers and frequent Types of volcanic eruptions, volcanic eruptions. The interior consists of a volcanic plateau with sand and lava fields, mountains and glaciers, and many Glacial stream, glacial rivers flow to the sea through the Upland and lowland, lowlands. Iceland i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Magnetic Resonance Imaging
Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to generate pictures of the anatomy and the physiological processes inside the body. MRI scanners use strong magnetic fields, magnetic field gradients, and radio waves to form images of the organs in the body. MRI does not involve X-rays or the use of ionizing radiation, which distinguishes it from computed tomography (CT) and positron emission tomography (PET) scans. MRI is a medical application of nuclear magnetic resonance (NMR) which can also be used for imaging in other NMR applications, such as NMR spectroscopy. MRI is widely used in hospitals and clinics for medical diagnosis, staging and follow-up of disease. Compared to CT, MRI provides better contrast in images of soft tissues, e.g. in the brain or abdomen. However, it may be perceived as less comfortable by patients, due to the usually longer and louder measurements with the subject in a long, confining tube, although ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Urine
Urine is a liquid by-product of metabolism in humans and many other animals. In placental mammals, urine flows from the Kidney (vertebrates), kidneys through the ureters to the urinary bladder and exits the urethra through the penile meatus (males) or urethral meatus of the vulva (females) during urination. In other vertebrates, urine is excreted through the cloaca. Urine contains water-soluble by-products of Cell (biology), cellular metabolism that are rich in nitrogen and must be clearance (medicine), cleared from the Circulatory system, bloodstream, such as urea, uric acid and creatinine. A urinalysis can detect nitrogenous wastes of the mammalian body. Urine plays an important role in the earth's nitrogen cycle. In balanced ecosystems, urine fertilizes the soil and thus helps plants to grow. Therefore, Reuse of excreta, urine can be used as a fertilizer. Some animals use it to territory (animal)#Scent marking, mark their territories. Historically, aged or fermented urine (kn ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood
Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood is composed of blood cells suspended in blood plasma. Plasma, which constitutes 55% of blood fluid, is mostly water (92% by volume), and contains proteins, glucose, mineral ions, and hormones. The blood cells are mainly red blood cells (erythrocytes), white blood cells (leukocytes), and (in mammals) platelets (thrombocytes). The most abundant cells are red blood cells. These contain hemoglobin, which facilitates oxygen transport by reversibly binding to it, increasing its solubility. Jawed vertebrates have an adaptive immune system, based largely on white blood cells. White blood cells help to resist infections and parasites. Platelets are important in the clotting of blood. Blood is circulated around the body through blood vessels by the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sampling (medicine)
In medicine, sampling is gathering of matter from the body to aid in the process of a medical diagnosis and/or evaluation of an indication (medicine), indication for treatment, further medical tests or other procedures. In this sense, the sample is the gathered matter, and the sampling tool or sampler is the person or material to collect the sample. Sampling is a prerequisite for many medical tests, but generally not for medical history, physical examination and radiologic tests. By sampling technique * Obtaining excretions or materials that leave the body anyway, such as urine, Feces, stool, sputum, or vomitus, by direct collection as they exit. A sample of saliva can also be collected from the mouth. * Surgery#Types of surgery, Excision (cutting out), a surgical method for the removal of solid or soft tissue samples. * Puncture (also called ''centesis'') followed by aspiration is the main method used for sampling of many types of tissues and body fluids. Examples are thoracoc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Laboratory Specimen
A laboratory specimen is sometimes a biological specimen of a medical patient's tissue, fluids, or other samples used for laboratory analysis to assist in differential diagnosis or staging of a disease process. These specimens are often the most reliable method of diagnosis, depending on the ailment. For example, breast cancer biopsies, performed on laboratory specimens of breast tissue, yield just a 2% rate of incorrect diagnosis. Laboratory specimens may also include feces. Types General types of cellular tissue extraction include: * Bone marrow aspiration * Cardiac tissue * Core * Endometrial biopsy * Endoscopic biopsy * Excisional and incisional * Fine-needle aspiration * Lymph node Preparation For a given medical process, a certain volume of specimen must be taken from the patient. Some specimen types also require special treatment, such as immediate mixture with an additive, or storage at a certain temperature. After extraction, all specimen containers m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ecosystem Restoration
Ecological restoration, or ecosystem restoration, is the process of assisting the recovery of an ecosystem that has been degraded, damaged, destroyed or transformed. It is distinct from conservation in that it attempts to retroactively repair already damaged ecosystems rather than take preventative measures. Ecological restoration can help to reverse biodiversity loss, combat climate change, support the provision of ecosystem services and support local economies. The United Nations has named 2021–2030 the Decade on Ecosystem Restoration. Habitat restoration involves the deliberate rehabilitation of a specific area to reestablish a functional ecosystem. This may differ from historical baselines (the ecosystem's original condition at a particular point in time). To achieve successful habitat restoration, it is essential to understand the life cycles and interactions of species, as well as the essential elements such as food, water, nutrients, space, and shelter needed to suppo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Great Barrier Reef
The Great Barrier Reef is the world's largest coral reef system, composed of over 2,900 individual reefs and 900 islands stretching for over over an area of approximately . The reef is located in the Coral Sea, off the coast of Queensland, Australia, separated from the coast by a channel wide in places and over deep. The Great Barrier Reef can be seen from outer space and is the world's biggest single structure made by living organisms. This reef structure is composed of and built by billions of tiny organisms, known as coral polyp (zoology), polyps. It supports a wide diversity of life and was selected as a World Heritage Site in 1981. CNN labelled it one of the Seven Wonders of the World#Seven Natural Wonders of the World, Seven Natural Wonders of the World in 1997. Australian World Heritage places included it in its list in 2007. The Queensland National Trust named it a state icon of Queensland in 2006. A large part of the reef is protected by the Great Barrier Reef Mar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetic Testing
Genetic testing, also known as DNA testing, is used to identify changes in DNA sequence or chromosome structure. Genetic testing can also include measuring the results of genetic changes, such as RNA analysis as an output of gene expression, or through biochemical analysis to measure specific protein output. In a medical setting, genetic testing can be used to diagnose or rule out suspected genetic disorders, predict risks for specific conditions, or gain information that can be used to customize medical treatments based on an individual's genetic makeup. Genetic testing can also be used to determine biological relatives, such as a child's biological parentage (genetic mother and father) through DNA paternity testing, or be used to broadly predict an individual's ancestry. Genetic testing of plants and animals can be used for similar reasons as in humans (e.g. to assess relatedness/ancestry or predict/diagnose genetic disorders), to gain information used for selective breed ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
