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Bharat Aggarwal
Bharat B. Aggarwal is an Indian-American biochemist. His research has been in the areas of cytokines, the role of inflammation in cancer, and the anti-cancer effects of spices and herbs, particularly curcumin (a chemical constituent of the spice turmeric). He was a professor in the Department of Clinical Immunology, Bioimmunotherapy, and Experimental Therapeutics at University of Texas MD Anderson Cancer Center in Houston, Texas. In 2012, MD Anderson launched a review of Aggarwal's research after the federal government notified them of allegations of fraud by academic whistleblowers in as many as 65 of Aggarwal's published papers, with the allegations involving images that had been reused and manipulated to represent different results. He retired at the end of 2015; his departure was not made public until February 2016. As of 2023, 30 papers published by Aggarwal have been retracted, ten others have received an expression of concern, and 17 others have been corrected. Career ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biochemistry
Biochemistry, or biological chemistry, is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology, and metabolism. Over the last decades of the 20th century, biochemistry has become successful at explaining living processes through these three disciplines. Almost all List of life sciences, areas of the life sciences are being uncovered and developed through biochemical methodology and research.#Voet, Voet (2005), p. 3. Biochemistry focuses on understanding the chemical basis that allows biomolecule, biological molecules to give rise to the processes that occur within living Cell (biology), cells and between cells,#Karp, Karp (2009), p. 2. in turn relating greatly to the understanding of tissue (biology), tissues and organ (anatomy), organs as well as organism structure and function.#Miller, Miller (2012). p. 62. Biochemistry is closely ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Doctor Of Philosophy
A Doctor of Philosophy (PhD, DPhil; or ) is a terminal degree that usually denotes the highest level of academic achievement in a given discipline and is awarded following a course of Postgraduate education, graduate study and original research. The name of the degree is most often abbreviated PhD (or, at times, as Ph.D. in North American English, North America), pronounced as three separate letters ( ). The University of Oxford uses the alternative abbreviation "DPhil". PhDs are awarded for programs across the whole breadth of academic fields. Since it is an earned research degree, those studying for a PhD are required to produce original research that expands the boundaries of knowledge, normally in the form of a Thesis, dissertation, and, in some cases, defend their work before a panel of other experts in the field. In many fields, the completion of a PhD is typically required for employment as a university professor, researcher, or scientist. Definition In the context o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
USC Annenberg School For Communication And Journalism
The USC Annenberg School for Communication and Journalism is a part of the University of Southern California in Los Angeles. It has 2,300 undergraduate and graduate students. Willow Bay is the dean. Prof. Hector Amaya is the Director of the School of Communication, Prof. Gordon Stables serves as Director of the School of Journalism. History The journalism program at USC dates back to 1916. In 1933, it became the School of Journalism within the USC College of Letters, Arts and Sciences. In 1971, the USC Annenberg School for Communication was founded, supported by an $8-million gift from Walter Annenberg. It was reorganized in 1994 to include the School of Journalism and the Department of Communication Arts. In 2000, producer Norman Lear pledged $5 million to establish a multidisciplinary research and public policy center at the USC Annenberg School, focused on the impact of the entertainment on news, information, and other aspects of modern culture. The school’s name officia ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Retraction Watch
Retraction Watch is a blog that reports on retractions of scientific papers and on related topics. The blog was launched in August 2010 and is produced by science writers Ivan Oransky (Former Vice President, Editorial ''Medscape'') and Adam Marcus (editor of ''Gastroenterology & Endoscopy News''). Its parent organization is the Center for Scientific Integrity, a US 501(c)(3) nonprofit organization. Motivation and scope In 2011, Oransky and Marcus pointed out in ''Nature'' that the peer review process for scholarly publications continues long after the publication date. They were motivated to launch ''Retraction Watch'' to encourage this continuation and to increase the transparency of the retraction process. They observed that retractions of papers generally are not announced, that the reasons for retractions are not publicized, and that other researchers or the public who are unaware of the retraction may make decisions based on invalid results. Oransky described an example ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Deccan Herald
''Deccan Herald'' is an Indian English-language daily newspaper published from the Indian state of Karnataka. It was founded by businessman K. N. Guruswamy and launched on 17 June 1948. It is published by The Printers Mysore, a privately held company owned by the Nettakallappa family, heirs of Guruswamy. It has seven editions printed from Bengaluru, Hubballi, Davanagere, Hosapete, Mysuru, Mangaluru, and Kalaburagi. History and background ''Deccan Herald'' was launched on 17 June 1948. Its founder, K. N. Guruswamy, in search of a suitable location for a news publishing business, purchased a bar and restaurant called Funnel's, that was owned by an Irish couple, in March 1948. Despite having no experience in the newspaper industry, Guruswamy, along with his close aides and well wishers, decided to launch two newspapers from Bangalore since there was no such title at the time. Veteran journalist Pothan Joseph served as its founding editor, which gave it a strong footing a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Office Of Research Integrity
The Office of Research Integrity (ORI) is a U.S. government agency that focuses on research integrity, especially in health. It was created when the Office of Scientific Integrity (OSI) in the National Institutes of Health (NIH) and the Office of Scientific Integrity Review (OSIR) in the Office of the Assistant Secretary for Health merged in May 1992. The Office of Research Integrity oversees and directs Public Health Service (PHS) research integrity activities on behalf of the Secretary of Health and Human Services, except for the regulatory research integrity activities of the Food and Drug Administration. Organizationally, ORI is located within the Office of the Assistant Secretary for Health (OASH) within the Office of the Secretary of Health and Human Services (OS), in the Department of Health and Human Services (HHS). Activities ORI carries out its responsibility by: * Developing policies, procedures and regulations related to the detection, investigation, and prevention of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell (journal)
''Cell'' is a peer-reviewed scientific journal publishing research papers across a broad range of disciplines within the life sciences. Areas covered include molecular biology, cell biology, systems biology, stem cells, developmental biology, genetics and genomics, proteomics, cancer research, immunology, neuroscience, structural biology, microbiology, virology, physiology, biophysics, and computational biology. The journal was established in 1974 by Benjamin LewinElsevier: ''Cell'': Home (accessed 12 December 2008) and is published twice monthly by Cell Press, owned by . |
Anti-cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor diet, lack of physical activity or excessive alcohol consumption. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. Infection with specific viruses, bacteria and parasites is an environmental factor causing approximately 16–18% of cancers worldwide. These infectious agents include ''Helicobacter pylori'', hepatitis B, hepatitis C, HPV, Epstein–Barr virus, Human T-lymphotropic virus 1, Kap ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Texas
The University of Texas at Austin (UT Austin, UT, or Texas) is a public research university in Austin, Texas, United States. Founded in 1883, it is the flagship institution of the University of Texas System. With 53,082 students as of fall 2023, it is also the largest institution in the system. The university is a major center for academic research, with research expenditures totaling $1.06 billion for the 2023 fiscal year. It joined the Association of American Universities in 1929. The university houses seven museums and seventeen libraries, including the Lyndon B. Johnson Presidential Library and the Blanton Museum of Art, and operates various auxiliary research facilities, such as the J. J. Pickle Research Campus and McDonald Observatory. UT Austin's athletics constitute the Texas Longhorns. The Longhorns have won four NCAA Division I National Football Championships, six NCAA Division I National Baseball Championships, sixteen NCAA Division I National Men's Swimming ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MD Anderson Cancer Center
The University of Texas MD Anderson Cancer Center (colloquially MD Anderson Cancer Center) is a comprehensive cancer center and autonomous university of the University of Texas System in Houston, Texas. It is the largest cancer center in the world and one of the original three NCI-designated comprehensive cancer centers in the country. It is both a degree-granting academic institution and a cancer treatment and research center located within the Texas Medical Center, the largest medical center and life sciences destination in the world. MD Anderson Cancer Center has consistently ranked #1 among the best hospitals for cancer care and research in the U.S. and worldwide, and it has held the #1 position 20 times in the last 23 years in ''U.S. News & World Report's'' Best Hospitals rankings for cancer care. As of 2023, MD Anderson Cancer Center is home to the highest number of cancer clinical trials in the world and has received more NCI-funded projects than any other U.S. institut ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lymphotoxin Alpha
Lymphotoxin-alpha (LT-α) formerly known as tumor necrosis factor-beta (TNF-β) is a protein that in humans is encoded by the ''LTA'' gene. Belonging to the hematopoietic cell line, LT-α exhibits anti-proliferative activity and causes the cellular destruction of tumor cell lines. As a cytotoxic protein, LT-α performs a variety of important roles in immune regulation depending on the form that it is secreted as. Unlike other members of the TNF superfamily, LT-α is only found as a soluble homotrimer, when found at the cell surface it is found only as a heterotrimer with LTβ. LT-α has a significant impact on the maintenance of the immune system including the development of secondary lymphoid organs. Absence of LT-α leads to the disruption of gastrointestinal development, prevents Peyer's patch development, and results in a disorganized spleen. As a signaling molecule, LT-α is involved in the regulation of cell survival, proliferation, differentiation, and apoptosis. LT- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
TNF-alpha
Tumor necrosis factor (TNF), formerly known as TNF-α, is a chemical messenger produced by the immune system that induces inflammation. TNF is produced primarily by activated macrophages, and induces inflammation by binding to its receptors on other cells. It is a member of the tumor necrosis factor superfamily, a family of transmembrane proteins that are cytokines, chemical messengers of the immune system. Excessive production of TNF plays a critical role in several inflammatory diseases, and TNF-blocking drugs are often employed to treat these diseases. TNF is produced primarily by macrophages but is also produced in several other cell types, such as T cells, B cells, dendritic cells, and mast cells. It is produced rapidly in response to pathogens, cytokines, and environmental stressors. TNF is initially produced as a type II transmembrane protein (tmTNF), which is then cleaved by TNF alpha converting enzyme (TACE) into a soluble form (sTNF) and secreted from the cell. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
