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Beverly Torok-Storb
Beverly Jo Torok-Storb (1948 – May 5, 2023) was an American physician who was Professor of Clinical Research at the Fred Hutchinson Cancer Research Center. Her work considered the stem cells that generate blood and the microenvironment of bone marrow. Early life and education Torok-Storb was born in 1948, in Erie, Pennsylvania, where she was raised in a public housing project. She became interested in biology during high school, then was an undergraduate student at PennWest Edinboro. Torok-Storb worked toward her doctorate at the University of Pittsburgh. Research and career Torok-Storb joined the Fred Hutchinson Cancer Research Center in 1978 and studied stem cells and the microenvironment of bone marrow. Her research identified the interactions between the stem cells in blood and the supportive cells in bone marrow, enabling critical transplants in leukemia and blood cancer. Prior to the work of Torok-Storb, it was assumed that bone marrow stromal cells could be derived ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Seattle, Washington
Seattle ( ) is the List of municipalities in Washington, most populous city in the U.S. state of Washington (state), Washington and in the Pacific Northwest region of North America. With a population of 780,995 in 2024, it is the List of United States cities by population, 18th-most populous city in the United States. The city is the county seat of King County, Washington, King County, the List of counties in Washington, most populous county in Washington. The Seattle metropolitan area's population is 4.02 million, making it the List of metropolitan statistical areas, 15th-most populous in the United States. Its growth rate of 21.1% between 2010 and 2020 made it one of the country's fastest-growing large cities. Seattle is situated on an isthmus between Puget Sound, an inlet of the Pacific Ocean, and Lake Washington. It is the northernmost major city in the United States, located about south of the Canada–United States border, Canadian border. A gateway for trade with East ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fred Hutchinson Cancer Research Center
The Fred Hutchinson Cancer Center, formerly known as the Fred Hutchinson Cancer Research Center and also known as Fred Hutch or The Hutch, is a cancer research institute established in 1975 in Seattle, Washington (state), Washington. History The center grew out of the Pacific Northwest Diabetes Research Institute, Pacific Northwest Research Foundation, founded in 1956 by William B. Hutchinson (physician), William B. Hutchinson (1909–1997). The Foundation was dedicated to the study of heart surgery, cancer, and diseases of the endocrine system. Hutchinson's younger brother Fred Hutchinson, Fred (1919–1964) was a Major League Baseball, major league pitcher and Manager (baseball), manager who died of lung cancer at age 45. The next year, William Hutchinson established the Fred Hutchinson Cancer Research Center as a division of the Pacific Northwest Research Foundation.Louis Fiset, December 30, 2004 for HistoryLink: The Free, Online Encyclopedia of Washington State HistorHutchi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Pittsburgh
The University of Pittsburgh (Pitt) is a Commonwealth System of Higher Education, state-related research university in Pittsburgh, Pennsylvania, United States. The university is composed of seventeen undergraduate and graduate schools and colleges at its Urban university, urban Pittsburgh campus, home to the university's central administration and around 28,000 undergraduate and graduate students. The 132-acre Pittsburgh campus includes various historic buildings that are part of the Schenley Farms Historic District, most notably its 42-story Gothic Revival architecture, Gothic revival centerpiece, the Cathedral of Learning. Pitt is a member of the Association of American Universities and is Carnegie Classification of Institutions of Higher Education, classified among "R1: Doctoral Universities – Very high research activity". Pitt traces its roots to the Pittsburgh Academy founded by Hugh Henry Brackenridge in 1787. While the city was still on the History of Pittsburgh#Gatewa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PennWest Edinboro
Pennsylvania Western University, Edinboro (abbreviated as PennWest Edinboro) is a campus of Pennsylvania Western University in Edinboro, Pennsylvania. The campus had an enrollment of 2,259 as of fall 2024. History PennWest Edinboro was founded in 1857 as Edinboro Academy, a private training school for Pennsylvania teachers, by the region's original Scottish settlers. It is the oldest training institution west of the Allegheny Mountains and the second-oldest in Pennsylvania. Edinboro Academy initially consisted of a modest two-story building that featured six classrooms. The school began with three instructors, 110 students, and one principal. The original building, known as Academy Hall, is currently used as the undergraduate admissions office. In 1861, Edinboro Academy affiliated with the state government of Pennsylvania to become the second State Normal School in Pennsylvania, also known as Northwest State Normal School. In 1914, the state purchased the school from the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stem Cell
In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can change into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type of cell in a cell lineage. They are found in both embryonic and adult organisms, but they have slightly different properties in each. They are usually distinguished from progenitor cells, which cannot divide indefinitely, and precursor or blast cells, which are usually committed to differentiating into one cell type. In mammals, roughly 50 to 150 cells make up the inner cell mass during the blastocyst stage of embryonic development, around days 5–14. These have stem-cell capability. '' In vivo'', they eventually differentiate into all of the body's cell types (making them pluripotent). This process starts with the differentiation into the three germ layers – the ectoderm, mesoderm and endoderm – at the gastrulation stage. However, whe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bone Marrow
Bone marrow is a semi-solid biological tissue, tissue found within the Spongy bone, spongy (also known as cancellous) portions of bones. In birds and mammals, bone marrow is the primary site of new blood cell production (or haematopoiesis). It is composed of Blood cell, hematopoietic cells, marrow adipose tissue, and supportive stromal cells. In adult humans, bone marrow is primarily located in the Rib cage, ribs, vertebrae, sternum, and Pelvis, bones of the pelvis. Bone marrow comprises approximately 5% of total body mass in healthy adult humans, such that a person weighing 73 kg (161 lbs) will have around 3.7 kg (8 lbs) of bone marrow. Human marrow produces approximately 500 billion blood cells per day, which join the Circulatory system, systemic circulation via permeable vasculature sinusoids within the medullary cavity. All types of Hematopoietic cell, hematopoietic cells, including both Myeloid tissue, myeloid and Lymphocyte, lymphoid lineages, are create ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Erie, Pennsylvania
Erie is a city on the south shore of Lake Erie and the county seat of Erie County, Pennsylvania, United States. It is the List of municipalities in Pennsylvania, fifth-most populous city in Pennsylvania and the most populous in Northwestern Pennsylvania with a population of 94,831 at the 2020 United States census, 2020 census. The two-county Erie–Meadville combined statistical area, Erie metropolitan area had a population of 270,876 in 2020. Erie is about from Buffalo, New York, Buffalo, from Cleveland, and from Pittsburgh. The city was named for the Native Americans in the United States, Native American Erie people who lived in the area until the mid-17th century. Its nicknames include "Gem City", a reference to its fine natural harbor, the "Gem of the Great Lakes"; and more recently, "Flagship City", from a City marketing, local marketing effort to play up the homeport of Oliver Hazard Perry's flagship USS Niagara (1813), ''Niagara''. Manufacturing continues to play a l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haematopoietic System
The haematopoietic system ( spelled hematopoietic system in American English) is the system in the body involved in the creation of the cells of blood. Structure Stem cells Haematopoietic stem cells (HSCs) reside in the medulla of the bone (bone marrow) and have the unique ability to give rise to all of the different mature blood cell types and tissues. HSCs are self-renewing cells: when they differentiate, at least some of their daughter cells remain as HSCs, so the pool of stem cells is not depleted. This phenomenon is called asymmetric division. The other daughters of HSCs (myeloid and lymphoid progenitor cells) can follow any of the other differentiation pathways that lead to the production of one or more specific types of blood cell, but cannot renew themselves. The pool of progenitors is heterogeneous and can be divided into two groups; long-term self-renewing HSC and only transiently self-renewing HSC, also called short-terms. This is one of the main vital processes in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Heart, Lung, And Blood Institute
The National Heart, Lung, and Blood Institute (NHLBI) is the third largest Institute of the National Institutes of Health, located in Bethesda, Maryland, United States. It is tasked with allocating about $3.6 billion in FY 2020 in tax revenue to advancing the understanding of the following issues: development and progression of disease, diagnosis of disease, treatment of disease, disease prevention, reduction of health care disparities within the American population, and advancing the effectiveness of the US medical system. NHLBI's Director is Gary H. Gibbons (2012–present). Operation In 1948, the National Heart Act established the National Heart Institute and the National Advisory Heart Council. The intramural research program was established a year later in 1949. In 1969, the National Heart Institute was renamed the National Heart and Lung Institute, and the scope of the institute was expanded. In 1976, it was given its current name, the National Heart, Lung, and Blood Ins ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1948 Births
Events January * January 1 ** The General Agreement on Tariffs and Trade (GATT) is inaugurated. ** The current Constitutions of Constitution of Italy, Italy and of Constitution of New Jersey, New Jersey (both later subject to amendment) go into effect. ** The railways of Britain are nationalized, to form British Railways. * January 4 – British rule in Burma, Burma gains its independence from the United Kingdom, becoming an independent republic, named the 'Post-independence Burma (1948–1962), Union of Burma', with Sao Shwe Thaik as its first President and U Nu its first Prime Minister. * January 5 – In the United States: ** Warner Brothers shows the first color newsreel (''Tournament of Roses Parade'' and the ''Rose Bowl Game''). ** The first Kinsey Reports, Kinsey Report, ''Sexual Behavior in the Human Male'', is published. * January 7 – Mantell UFO incident: Kentucky Air National Guard pilot Thomas Mantell crashes while in pursuit of an unidentified fl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2023 Deaths
This is a list of lists of deaths of notable people, organized by year. New deaths articles are added to their respective month (e.g., Deaths in ) and then linked below. 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 Earlier years ''Deaths in years earlier than this can usually be found in the main articles of the years.'' See also * Lists of deaths by day * Deaths by year (category) {{DEFAULTSORT:deaths by year ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
People From Erie, Pennsylvania
The term "the people" refers to the public or Common people, common mass of people of a polity. As such it is a concept of human rights law, international law as well as constitutional law, particularly used for claims of popular sovereignty. In contrast, a people is any plurality of Person, persons considered as a whole. Used in politics and law, the term "a people" refers to the collective or community of an ethnic group or nation. Concepts Legal Chapter One, Article One of the Charter of the United Nations states that "peoples" have the right to self-determination. Though the mere status as peoples and the right to self-determination, as for example in the case of Declaration on the Rights of Indigenous Peoples, Indigenous peoples (''peoples'', as in all groups of indigenous people, not merely all indigenous persons as in ''indigenous people''), does not automatically provide for independence, independent sovereignty and therefore secession. Indeed, judge Ivor Jennings i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
