Bernhard Keppler
Bernhard K. Keppler is a German bioinorganic chemist and physician. He is chair of inorganic chemistry at the University of Vienna, head of the Institute of Inorganic Chemistry and dean of the Faculty of Chemistry. Education and career Keppler earned his diploma's degree in chemistry in 1979, Ph.D. in chemistry from the University of Heidelberg in 1981, licence to practice medicine (approbation) in 1984 and second Ph.D. in medicine from German Cancer Research Center in 1986. He was promoted to university lecturer in inorganic chemistry in 1990 at the University of Heidelberg and assigned a chair in inorganic chemistry at University of Vienna with tenure in 1995. He is dean of the Faculty of chemistry since 2008, head of the inter-university research cluster ''Translational Cancer Therapy Research'' (in cooperation with the Medical University of Vienna and ) and deputy head of the research network ''Chemistry, Microbiology and Environmental Systems Science'' (in cooperation with t ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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University Of Heidelberg
} Heidelberg University, officially the Ruprecht Karl University of Heidelberg, (german: Ruprecht-Karls-Universität Heidelberg; la, Universitas Ruperto Carola Heidelbergensis) is a public university, public research university in Heidelberg, Baden-Württemberg, Germany. Founded in 1386 on instruction of Pope Urban VI, Heidelberg is List of universities in Germany#Universities by years of existence, Germany's oldest university and one of the List of oldest universities in continuous operation, world's oldest surviving universities; it was the third university established in the Holy Roman Empire. Heidelberg is one of the most prestigious and highly ranked universities in Europe and the world. Heidelberg has been a coeducational institution since 1899. The university consists of twelve Faculty (division), faculties and offers degree programmes at undergraduate, graduate education, graduate and habilitation, postdoctoral levels in some 100 disciplines. The language of instruction ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Medicine
Medicine is the science and Praxis (process), practice of caring for a patient, managing the diagnosis, prognosis, Preventive medicine, prevention, therapy, treatment, Palliative care, palliation of their injury or disease, and Health promotion, promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention (medical), prevention and therapy, treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, medical genetics, genetics, and medical technology to diagnosis (medical), diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, splint (medicine), external splints and traction, medical devices, biologic medical product, biologics, and Radiation (medicine), ionizing radiation, amongst others. Medicine has been practiced since Prehistoric medicine, prehistoric times, and for most o ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Year Of Birth Missing (living People)
A year or annus is the orbital period of a planetary body, for example, the Earth, moving in its orbit around the Sun. Due to the Earth's axial tilt, the course of a year sees the passing of the seasons, marked by change in weather, the hours of daylight, and, consequently, vegetation and soil fertility. In temperate and subpolar regions around the planet, four seasons are generally recognized: spring, summer, autumn and winter. In tropical and subtropical regions, several geographical sectors do not present defined seasons; but in the seasonal tropics, the annual wet and dry seasons are recognized and tracked. A calendar year is an approximation of the number of days of the Earth's orbital period, as counted in a given calendar. The Gregorian calendar, or modern calendar, presents its calendar year to be either a common year of 365 days or a leap year of 366 days, as do the Julian calendars. For the Gregorian calendar, the average length of the calendar yea ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Heidelberg University Alumni
Heidelberg (; Palatine German: '''') is a city in the German state of Baden-Württemberg, situated on the river Neckar in south-west Germany. As of the 2016 census, its population was 159,914, of which roughly a quarter consisted of students. Located about south of Frankfurt, Heidelberg is the fifth-largest city in Baden-Württemberg. Heidelberg is part of the densely populated Rhine-Neckar Metropolitan Region. Heidelberg University, founded in 1386, is Germany's oldest and one of Europe's most reputable universities. Heidelberg is a scientific hub in Germany and home to several internationally renowned research facilities adjacent to its university, including the European Molecular Biology Laboratory and four Max Planck Institutes. The city has also been a hub for the arts, especially literature, throughout the centuries, and it was designated a " City of Literature" by the UNESCO Creative Cities Network. Heidelberg was a seat of government of the former Electorate o ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Academic Staff Of The University Of Vienna
An academy (Attic Greek: Ἀκαδήμεια; Koine Greek Ἀκαδημία) is an institution of secondary education, secondary or tertiary education, tertiary higher education, higher learning (and generally also research or honorary membership). The name traces back to Plato's school of philosophy, founded approximately 385 BC at Akademia, a sanctuary of Athena, the goddess of wisdom and Skills, skill, north of Ancient Athens, Athens, Greece. Etymology The word comes from the ''Academy'' in ancient Greece, which derives from the Athenian hero, ''Akademos''. Outside the city walls of Athens, the Gymnasium (ancient Greece), gymnasium was made famous by Plato as a center of learning. The sacred space, dedicated to the goddess of wisdom, Athena, had formerly been an olive Grove (nature), grove, hence the expression "the groves of Academe". In these gardens, the philosopher Plato conversed with followers. Plato developed his sessions into a method of teaching philosophy and in 3 ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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BOLD-100
BOLD-100, or sodium trans- etrachlorobis (1H-indazole)ruthenate(III)'', is a ruthenium-based anti-cancer therapeutic in clinical development. As of February 2024, BOLD-100 was being tested in a Phase 1b/2a clinical trial in 117 patients with advanced gastrointestinal cancers in combination with the chemotherapy regimen FOLFOX. BOLD-100 is being developed by Bold Therapeutics Inc. Structure BOLD-100 has an octahedral structure with two trans indazoles and four chloride ligands in the equatorial plane. The primary cation for BOLD-100 is sodium. BOLD-100’s impurity profile contains trace quantities of cesium BOLD-100 derivatives BOLD-100 is sodium trans- etrachlorobis (1H-indazole) ruthenate(III)with cesium as an intermediate salt form. BOLD-100 was developed from the closely related ruthenium molecule KP1339 (also known as IT-139 or NKP-1339) which is also sodium trans- etrachlorobis (1H-indazole) ruthenate(III) but has different manufacturing methods and purity profiles. ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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KP1019
KP1019, or indazole ''trans''- etrachlorobis(1''H''-indazole)ruthenate(III)'', is one of four ruthenium anti-cancer drugs to enter into phase I clinical trials, the others being BOLD-100, NAMI-A and TLD-1433. Research into ruthenium-based drugs has provided novel alternatives for platinum-based chemotherapeutics such as Cisplatin and its derivatives. KP1019 is useful for metastatic tumors and cis-platin resistant tumors. It exhibits potent cytotoxicity against primary tumors, particularly in colorectal cancer. Structure and properties KP1019 has an octahedral structure with two trans N-donor indazole and four chloride ligands in the equatorial plane. It has a low solubility in water, which makes it difficult to transport in the bloodstream. The Ru-Cl bonds are labile and KP1019 readily exchanges its chloro ligands in the presence of water. KP1019 derivatives Due to its low solubility in water, KP1019 is often prepared as its sodium salt, the basis for KP- ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Anticancer Research
''Anticancer Research'' is an independent international peer-reviewed medical journal published by thInternational Institute of Anticancer Research addressing experimental and clinical topics in oncology. Issues are released monthly print and online (by Highwire Press), and an annual Index is also published. Anticancer Research was established in 1981 by John G. Delinassios. According to the ''Journal Citation Reports'', the journal had a 2020 impact factor of 2.480 and 25,656 total cites. The 2020 rejection rate was 68%. According to Scimago, the journal belongs to the second quartile (Q2) in the "Medicine" category. Abstracting and indexing Articles in ''Anticancer Research'' are abstracted and/or indexed by: * BIOBASE *Biological Abstracts * CAM abstracts * Cambridge Scientific Abstracts * Current Contents (Life Sciences) * EMBASE * EMBiology *GEOBASE * Pubmed/Medline * Science Citation Index * Scopus Scopus is Elsevier's abstract and citation database launched in 2 ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Translational Cancer Therapy Research
Translation is the communication of the Meaning (linguistic), meaning of a #Source and target languages, source-language text by means of an Dynamic and formal equivalence, equivalent #Source and target languages, target-language text. The English language draws a terminology, terminological distinction (which does not exist in every language) between ''translating'' (a written text) and ''Language interpretation, interpreting'' (oral or Sign language, signed communication between users of different languages); under this distinction, translation can begin only after the appearance of writing within a language community. A translator always risks inadvertently introducing source-language words, grammar, or syntax into the target-language rendering. On the other hand, such "spill-overs" have sometimes imported useful source-language calques and loanwords that have enriched target languages. Translators, including early translators of sacred texts, have helped shape the very l ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |