Basmisanil
Basmisanil (; developmental codes RG-1662 and RO5186582) is a highly selective inverse agonist/ negative allosteric modulator of α5 subunit-containing GABAA receptors which is under development by Roche for the treatment of cognitive impairment associated with Down syndrome Down syndrome or Down's syndrome, also known as trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. It is usually associated with physical growth delays, mild to moderate intellectual dis .... As of June 2016, it is no longer studied. It is studied with schizophrenia patients. See also * List of investigational antipsychotics * GABAA receptor negative allosteric modulator * GABAA receptor § Ligands References External links Basmisanil - AdisInsight Fluoroarenes GABAA receptor negative allosteric modulators Nicotinamides Nootropics Isoxazoles {{Nervous-system-drug-stub ...
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