Bartley P. Griffith
Bartley P. Griffith (born 1949) is an American heart surgeon. Griffith joined Muhammad Mohiuddin's MD Xenoheart laboratory in 2018. Together, they were able to demonstrate that the heart of a genetically altered pig could support life when transplanted into an orthotopic position in the chest for up to 9 months. Griffith and Mohiuddin performed the first successful xenotransplantation of a genetically modified pig heart to a human on January 7, 2022. The recipient was 57-year-old David Bennett Sr. The procedure occurred at the University of Maryland Medical Center. Due to complications, David Bennett Sr died on March 8, 2022. On September 20, 2023, Bartley P. Griffith performed his second pig heart transplant. See also * Christiaan Barnard * Xenotransplantation * Heart transplantation A heart transplant, or a cardiac transplant, is a surgical transplant procedure performed on patients with end-stage heart failure when other medical or surgical treatments have failed. , t ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Living People
Purpose: Because living persons may suffer personal harm from inappropriate information, we should watch their articles carefully. By adding an article to this category, it marks them with a notice about sources whenever someone tries to edit them, to remind them of WP:BLP (biographies of living persons) policy that these articles must maintain a neutral point of view, maintain factual accuracy, and be properly sourced. Recent changes to these articles are listed on Special:RecentChangesLinked/Living people. Organization: This category should not be sub-categorized. Entries are generally sorted by family name In many societies, a surname, family name, or last name is the mostly hereditary portion of one's personal name that indicates one's family. It is typically combined with a given name to form the full name of a person, although several give .... Maintenance: Individuals of advanced age (over 90), for whom there has been no new documentation in the last ten ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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American Surgeons
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label that was previously known as Def American * American University, in Washington, D.C. Sports teams S ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Dhaniram Baruah
Dhaniram Baruah is an Indian heart surgeon from Assam, known for his work in the field of xenotransplantation. He is popularly known as India's ''Pig Heart Doctor''. On 1 January 1997, he became the first heart surgeon in the world to transplant a pig's heart in a human body. Although the recipient died subsequently, it was a precursor to the first successful pig-to-human heart transplant performed 25 years later by Bartley P. Griffith in January 2022. While Griffith used a genetically modified pig's heart, Barua had transplanted a normal pig heart. Barua is also the founder of Dr Dhaniram Baruah Heart Institute & Research Centre. He can only communicate through hand gestures after a brain stroke left him unable to speak. Experiments, claims and controversies Throughout his career Barua has courted controversies due to his maverick ideas and unconventional methods. The pig heart transplanted by Barua in his patient Purna Saikia worked for seven days, after which due to implicat ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Christiaan Barnard
Christiaan Neethling Barnard (8November 19222September 2001) was a South African cardiac surgeon who performed the world's first human-to-human heart transplant operation. On 3 December 1967, Barnard transplanted the heart of accident victim Denise Darvall into the chest of 54-year-old Louis Washkansky, who regained full consciousness and was able to talk easily with his wife, before dying 18 days later of pneumonia, largely brought on by the anti-rejection drugs that suppressed his immune system. Barnard had told Mr. and Mrs. Washkansky that the operation had an 80% chance of success, an assessment which has been criticised as misleading. Barnard's second transplant patient, Philip Blaiberg, whose operation was performed at the beginning of 1968, returned home from the hospital and lived for a year and a half. Born in Beaufort West, Cape Province, Barnard studied medicine and practised for several years in his native South Africa. As a young doctor experimenting on dogs ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Genetically Modified Animal
Genetically modified animals are animals that have been genetically modified for a variety of purposes including producing drugs, enhancing yields, increasing resistance to disease, etc. The vast majority of genetically modified animals are at the research stage while the number close to entering the market remains small. Production The process of genetically engineering mammals is a slow, tedious, and expensive process.Murray, Joo (20)Genetically modified animals. Canada: Brainwaving As with other genetically modified organisms (GMOs), first genetic engineers must isolate the gene they wish to insert into the host organism. This can be taken from a cell containing the gene or artificially synthesised. If the chosen gene or the donor organism's genome has been well studied it may already be accessible from a genetic library. The gene is then combined with other genetic elements, including a promoter and terminator region and usually a selectable marker. A number of techni ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Xenotransplantation
Xenotransplantation (''xenos-'' from the Greek meaning "foreign" or strange), or heterologous transplant, is the transplantation of living cells, tissues or organs from one species to another.Xenotransplantation Definition by the World Health Organization Such cells, tissues or organs are called xenografts or xenotransplants. It is contrasted with (from other individual of same species), syngeneic transplantation or isotransplantation (grafts transplanted between two genetically identical individuals of the same species), and [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Doctor Of Medicine
A Doctor of Medicine (abbreviated MD, from the Latin language, Latin ) is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the ''MD'' denotes a professional degree of physician. This generally arose because many in 18th-century medical professions trained in Scotland, which used the MD degree nomenclature. In England, however, Bachelor of Medicine, Bachelor of Surgery (MBBS) was used: in the 19th century, it became the standard in Scotland too. Thus, in the United Kingdom, Republic of Ireland, Ireland and other countries, the MD is a research doctorate, honorary degree, honorary doctorate or applied clinical degree restricted to those who already hold a professional degree (Bachelor's/Master's/Doctoral) in medicine. In those countries, the equivalent professional degree to the North American, and some others' usage of MD is still typically titled Bachelor of Medicine, Bachelor of Surgery. History The fi ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Heart Transplantation
A heart transplant, or a cardiac transplant, is a surgical transplant procedure performed on patients with end-stage heart failure when other medical or surgical treatments have failed. , the most common procedure is to take a functioning heart from a recently deceased organ donor (brain death is the most common) and implant it into the patient. The patient's own heart is either removed and replaced with the donor heart ( orthotopic procedure) or, much less commonly, the recipient's diseased heart is left in place to support the donor heart (heterotopic, or "piggyback", transplant procedure). Approximately 5,000 heart transplants are performed each year worldwide, more than half of which are in the US. Post-operative survival periods average 15 years. Heart transplantation is not considered to be a cure for heart disease; rather it is a life-saving treatment intended to improve the quality and duration of life for a recipient. History American medical researcher Simon Fle ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |