Barbara Mawer
Elizabeth Barbara Mawer (née Entwistle, 6 March 1936 – 7 March 2006) was a British biochemist and medical researcher. She was regarded as a "highly influential figure in the calcium homoeostasis field". Early life and education Barbara Entwistle was born on 6 March 1939 in Blackburn to Thomas Entwistle, a teacher, and Gladys Mary Entwistle (née Cornall). She attended Blackburn High School and Queen Mary School in Lytham St Annes. She received a BSc in biochemistry from the University of Edinburgh in 1957. She stayed there to conduct research, supervised by Guy Marrian, and in 1961 received a PhD for her thesis entitled ''The metabolism of cholesterol in the animal body''. From 1958 to 1963 she also worked as an assistant lecturer at Edinburgh. Scientific career After taking a break from working in order to look after her young children, in 1967 Mawer became a research associate at the University of Manchester, studying vitamin D and metabolic bone disease with William ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Blackburn
Blackburn () is an industrial town and the administrative centre of the Blackburn with Darwen borough in Lancashire, England. The town is north of the West Pennine Moors on the southern edge of the Ribble Valley, east of Preston and north-northwest of Manchester. Blackburn is the core centre of the wider unitary authority area along with the town of Darwen. It is one of the largest districts in Lancashire, with commuter links to neighbouring cities of Manchester, Salford, Preston, Lancaster, Liverpool, Bradford and Leeds. At the 2011 census, Blackburn had a population of 117,963, whilst the wider borough of Blackburn with Darwen had a population of 150,030. Blackburn had a population of 117,963 in 2011, with 30.8% being people of ethnic backgrounds other than white British. A former mill town, textiles have been produced in Blackburn since the middle of the 13th century, when wool was woven in people's houses in the domestic system. Flemish weavers who sett ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Calcium
Calcium is a chemical element with the symbol Ca and atomic number 20. As an alkaline earth metal, calcium is a reactive metal that forms a dark oxide-nitride layer when exposed to air. Its physical and chemical properties are most similar to its heavier homologues strontium and barium. It is the fifth most abundant element in Earth's crust, and the third most abundant metal, after iron and aluminium. The most common calcium compound on Earth is calcium carbonate, found in limestone and the fossilised remnants of early sea life; gypsum, anhydrite, fluorite, and apatite are also sources of calcium. The name derives from Latin ''calx'' " lime", which was obtained from heating limestone. Some calcium compounds were known to the ancients, though their chemistry was unknown until the seventeenth century. Pure calcium was isolated in 1808 via electrolysis of its oxide by Humphry Davy, who named the element. Calcium compounds are widely used in many industries: in foods and p ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Alumni Of The University Of Edinburgh
This is a list of notable graduates as well as non-graduate former students, academic ranks in the United Kingdom, academic staff, and university officials of the University of Edinburgh in Scotland. It also includes those who may be considered alumni by extension, having studied at institutions that later merged with the University of Edinburgh. The university is associated with 19 Nobel Prize laureates, three Turing Award winners, an Abel Prize laureate and Fields Medallist, four Pulitzer Prize winners, three List of prime ministers of the United Kingdom by education, Prime Ministers of the United Kingdom, and several Olympic Games, Olympic gold medallists. Government and politics Heads of state and government United Kingdom Cabinet and Party Leaders Scottish Cabinet and Party Leaders Current Members of the House of Commons * Wendy Chamberlain, MP for North East Fife (UK Parliament constituency), North East Fife * Joanna Cherry, MP for Edinburgh South West (UK Pa ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Liver Cancer
Liver cancer (also known as hepatic cancer, primary hepatic cancer, or primary hepatic malignancy) is cancer that starts in the liver. Liver cancer can be primary (starts in liver) or secondary (meaning cancer which has spread from elsewhere to the liver, known as liver metastasis). Liver metastasis is more common than that which starts in the liver. Liver cancer is increasing globally. Primary liver cancer is globally the sixth-most frequent cancer and the fourth-leading cause of death from cancer. In 2018, it occurred in 841,000 people and resulted in 782,000 deaths globally. Higher rates of liver cancer occur where hepatitis B and C are common, including Asia and sub-Saharan Africa. Males are more often affected with hepatocellular carcinoma (HCC) than females. Diagnosis is most frequent among those 55 to 65 years old. The leading cause of liver cancer is cirrhosis due to hepatitis B, hepatitis C or alcohol. Other causes include aflatoxin, non-alcoholic fatty liver d ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Christie Hospital
The Christie Hospital in Manchester, England, is one of the largest cancer treatment centres in Europe. It is managed by The Christie NHS Foundation Trust. History The hospital was established by a committee under the chairmanship of Richard Christie, a lawyer and academic, as the Cancer Pavilion and Home for Incurables. It opened at a site in Lorne Street off Oxford Road in 1892, at a site in Chorlton-upon-Medlock now occupied by Manchester Royal Infirmary. The name of the pavilion was changed by the addition of "Christie" in 1901 after Christie himself had died. In 1929 it had 34 beds and was resorted to by patients from northern England and north Wales; it was then the only provincial hospital solely for cancer treatment. Associated with it was the Radium Institute (founded in 1914, which moved to Nelson Street in 1921). In 1928, the hospital had 14 beds, 374 in-patients and over 7,000 out-patients who were given radium treatment. Together with the Holt Institute, the Chr ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Pharmacology
Pharmacology is a branch of medicine, biology and pharmaceutical sciences concerned with drug or medication action, where a drug may be defined as any artificial, natural, or endogenous (from within the body) molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism (sometimes the word ''pharmacon'' is used as a term to encompass these endogenous and exogenous bioactive species). More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties,functions,sources,synthesis and drug design, molecular and cellular mechanisms, organ/systems mechanisms, signal transduction/cellular communication, molecular diagnostics, interactions, chemical biology, therapy, and medical applications and antipathogenic capabili ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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North West Regional Assembly
The North West Regional Assembly (NWRA) was the regional chamber for the North West England region of the England. It was based at Wigan, in Greater Manchester. It was abolished in July 2008. Creation and functions The assembly was created by the Regional Development Agencies Act 1998. The first meeting was held in 1999. In July 2003 the assembly was reconstituted to combine its existing functions with those of the regional arm of the Local Government Association and of the Regional Employers Organisation. The NWRA acted as the representative voice of the region and worked to promote the economic, environmental and social well-being of the North West of England. The key functions of the assembly were: *Co-ordinate the public expenditure of local authorities *Act as regional planning body *Scrutinise the work of the Northwest Regional Development Agency Abolition Following criticism of the regional assemblies, it was proposed in July 2007 that they will be axed, losing the ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Liberal Democrats (UK)
The Liberal Democrats (commonly referred to as the Lib Dems) are a liberal political party in the United Kingdom. Since the 1992 general election, with the exception of the 2015 general election, they have been the third-largest UK political party by the number of votes cast. They have 14 Members of Parliament in the House of Commons, 83 members of the House of Lords, four Members of the Scottish Parliament and one member in the Welsh Senedd. The party has over 2,500 local council seats. The party holds a twice-per-year Liberal Democrat Conference, at which party policy is formulated, with all party members eligible to vote, under a one member, one vote system. The party served as the junior party in a coalition government with the Conservative Party between 2010 and 2015; with Scottish Labour in the Scottish Executive from 1999 to 2007, and with Welsh Labour in the Welsh Government from 2000 to 2003 and from 2016 to 2021. In 1981, an electoral alliance was establis ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Warrington Borough Council
Warrington Borough Council is the local authority of Warrington, Cheshire, England. It is a unitary authority, having the powers of a non-metropolitan county and district council combined. It provides a full range of local government services including Council Tax billing, libraries, social services, processing planning applications, waste collection and disposal, and it is a local education authority. Within Warrington Borough are parts of the historic counties of both Lancashire and Cheshire. Powers and functions The local authority derives its powers and functions from the Local Government Act 1972 and subsequent legislation. For the purposes of local government, Warrington is within a non-metropolitan area of England. As a unitary authority, Warrington Borough Council has the powers and functions of both a non-metropolitan county and district council combined. In its capacity as a district council it is a billing authority collecting Council Tax and business rates, it pr ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Warrington
Warrington () is a town and unparished area in the Borough of Warrington, borough of the same name in the ceremonial county of Cheshire, England, on the banks of the River Mersey. It is east of Liverpool, and west of Manchester. The population in 2019 was estimated at 165,456 for the town's urban area, and just over 210,014 for the entire borough, the latter being more than double that of 1968 when it became a New towns in the United Kingdom, new town. Warrington is the largest town in the ceremonial county of Cheshire. In 2011 the unparished area had a population of 58,871. Warrington was founded by the Roman Empire, Romans at an important crossing place on the River Mersey. A new settlement was established by the Saxons, Saxon Wærings. By the Middle Ages, Warrington had emerged as a market town at the lowest bridging point of the river. A local tradition of textile and tool production dates from this time. The town of Warrington (north of the Mersey) is within the bounda ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Thelwall
Thelwall is a suburban village in the Borough of Warrington, Cheshire, England, close to the Lymm junction of the M6 motorway. History A fortified village was established at Thelwall in 923, in the reign of King Edward the Elder, which is mentioned in two very early sources, including the ''Anglo-Saxon Chronicle'': "Kynge Edwarde made a cite at Thelewall in h northe parte of h Marches, nye the water of Mersee, where he put certeyne knyghtes."—Higden's Polychronicon "A.D. 923. This year went King Edward with an army, late in the harvest, to Thelwall; and ordered the borough to be repaired, and inhabited, and manned. And he ordered another army also from the population of Mercia, the while he sat there to go to Manchester in Northumbria, to repair and to man it. This year died Archbishop Plegmund; and King Reynold won York."—''Anglo-Saxon Chronicle'' An inscription on the Pickering Arms records that "In the year 920 King Edward the Elder founded a city here and called it ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bone Research Society
A bone is a rigid organ that constitutes part of the skeleton in most vertebrate animals. Bones protect the various other organs of the body, produce red and white blood cells, store minerals, provide structure and support for the body, and enable mobility. Bones come in a variety of shapes and sizes and have complex internal and external structures. They are lightweight yet strong and hard and serve multiple functions. Bone tissue (osseous tissue), which is also called bone in the uncountable sense of that word, is hard tissue, a type of specialized connective tissue. It has a honeycomb-like matrix internally, which helps to give the bone rigidity. Bone tissue is made up of different types of bone cells. Osteoblasts and osteocytes are involved in the formation and mineralization of bone; osteoclasts are involved in the resorption of bone tissue. Modified (flattened) osteoblasts become the lining cells that form a protective layer on the bone surface. The mineralized matrix ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |