Bacilladnavirus
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Bacilladnavirus
''Bacilladnaviridae'' is a family of single-stranded DNA viruses that primarily infect diatom A diatom (Neo-Latin ''diatoma'') is any member of a large group comprising several Genus, genera of algae, specifically microalgae, found in the oceans, waterways and soils of the world. Living diatoms make up a significant portion of Earth's B ...s. Characteristics Similar to other eukaryotic ssDNA viruses, bacilladnaviruses are likely to replicate their genomes by the rolling-circle mechanism, initiated by the virus-encoded endonuclease (Rep). However, the latter protein of bacilladnaviruses displays unique conserved motifs and in phylogenetic trees forms a monophyletic clade separated from other groups of ssDNA viruses. The capsid protein of bacilladnaviruses has the jelly-roll fold and is most closely related to the corresponding proteins from members of the family '' Nodaviridae'', which have ssRNA genomes. Taxonomy The following genera are recognized: *'' Aberdnavirus'' *'' ...
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SsDNA Viruses
Deoxyribonucleic acid (; DNA) is a polymer composed of two polynucleotide chains that coil around each other to form a double helix. The polymer carries genetic instructions for the development, functioning, growth and reproduction of all known organisms and many viruses. DNA and ribonucleic acid (RNA) are nucleic acids. Alongside proteins, lipids and complex carbohydrates (polysaccharides), nucleic acids are one of the four major types of macromolecules that are essential for all known forms of life. The two DNA strands are known as polynucleotides as they are composed of simpler monomeric units called nucleotides. Each nucleotide is composed of one of four nitrogen-containing nucleobases (cytosine guanine adenine or thymine , a sugar called deoxyribose, and a phosphate group. The nucleotides are joined to one another in a chain by covalent bonds (known as the phosphodiester linkage) between the sugar of one nucleotide and the phosphate of the next, resulting in a ...
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Diatom
A diatom (Neo-Latin ''diatoma'') is any member of a large group comprising several Genus, genera of algae, specifically microalgae, found in the oceans, waterways and soils of the world. Living diatoms make up a significant portion of Earth's Biomass (ecology), biomass. They generate about 20 to 50 percent of the oxygen produced on the planet each year, take in over 6.7 billion tonnes of silicon each year from the waters in which they live, and constitute nearly half of the organic material found in the oceans. The Protist shell, shells of dead diatoms are a significant component of marine sediment, and the entire Amazon basin is fertilized annually by 27 million tons of diatom shell dust transported by transatlantic winds from the African Sahara, much of it from the Bodélé Depression, which was once made up of a system of fresh-water lakes. Diatoms are unicellular organisms: they occur either as solitary cells or in Colony (biology), colonies, which can take the shape of ribb ...
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Jelly-roll Fold
The jelly roll or Swiss roll fold is a protein fold or supersecondary structure composed of eight beta strands arranged in two four-stranded sheets. The name of the structure was introduced by Jane S. Richardson in 1981, reflecting its resemblance to the jelly or Swiss roll cake. The fold is an elaboration on the Greek key motif and is sometimes considered a form of beta barrel. It is very common in viral proteins, particularly viral capsid proteins. Taken together, the jelly roll and Greek key structures comprise around 30% of the all-beta proteins annotated in the Structural Classification of Proteins (SCOP) database. Structure The basic jelly roll structure consists of eight beta strands arranged in two four-stranded antiparallel beta sheets which pack together across a hydrophobic interface here citation... uniprot The strands are traditionally labeled B through I for the historical reason that the first solved structure, of a jelly roll capsid protein from the tomato bus ...
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Nodaviridae
''Nodaviridae'' is a family of nonenveloped positive-strand RNA viruses. Vertebrates and invertebrates serve as natural hosts. Diseases associated with this family include: viral encephalopathy and retinopathy in fish. There are two genera in the family. History The name of the family is derived from the Japanese village of Nodamura, Iwate Prefecture where Nodamura virus was first isolated from '' Culex tritaeniorhynchus'' mosquitoes. Virology Structure The virus is not enveloped and has an icosahedral capsid (triangulation number = 3) ranging from 29 to 35 nm in diameter. The capsid is constructed of 32 capsomers. Genome The genome is linear, positive sense, bipartite (composed of two segments – RNA1 and RNA2) single stranded RNA consisting of 4500 nucleotides with a 5’ terminal methylated Methylation, in the chemical sciences, is the addition of a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group. Methylation is a form ...
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