|
Arrowsmith System
Arrowsmith was a literature-based discovery system built by Don R. Swanson using the concept of undiscovered public knowledge. He called it Arrowsmith: ‘An intellectual adventure’ Introduction The tool has a search mode that assists the user in looking for items or concepts that may be present in common between two distinct sets of articles. Another context for using the search mode is when the user wants to find information that is present in one field that may be relevant to another field of inquiry. The user will be guided through two PubMed searches to retrieve bio-medical articles from the MEDLINE database: the first search defines "literature A" and the second defines "literature C." The program then generates a "B-list" of words and phrases found in the titles of both sets of literature. The B-list is displayed ranked by relevance, and can be restricted to certain semantic categories (e.g. anatomical regions, or disorders, or drugs). For each B-term of interest, one ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Literature-based Discovery
Literature-based discovery (LBD), also called literature-related discovery (LRD) is a form of knowledge extraction and automated hypothesis generation that uses papers and other academic publications (the "literature") to find new relationships between existing knowledge (the "discovery"). Literature-based discovery aims to discover new knowledge by connecting information which have been explicitly stated in literature to deduce connections which have not been explicitly stated. LBD can help researchers to quickly discover and explore hypotheses as well as gain information on relevant advances inside and outside of their niches and increase interdisciplinary information sharing. The most basic and widespread type of LBD is called the ABC paradigm because it centers around three concepts called A, B and C. It states that if there is a connection between A and B and one between B and C, then there is one between A and C which, if not explicitly stated, is yet to be explored. Histo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Raynaud's Phenomenon
Raynaud syndrome, also known as Raynaud's phenomenon, eponymously named after the physician Auguste Gabriel Maurice Raynaud, who first described it in his doctoral thesis in 1862, is a medical condition in which the spasm of small arteries causes episodes of reduced blood flow to end arterioles. Typically, the fingers, and less commonly, the toes, are involved. Rarely, the nose, ears, or lips are affected. The episodes classically result in the affected part turning white and then blue. Often, numbness or pain occurs. As blood flow returns, the area turns red and burns. The episodes typically last minutes but can last several hours. Episodes are typically triggered by cold or emotional stress. Primary Raynaud's, also known as idiopathic, means that it is spontaneous, of unknown cause, and unrelated to another disease. Secondary Raynaud's occurs as a result of another condition and has an older age at onset; episodes are intensely painful and can be asymmetric and associated wi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Open Source
Open source is source code that is made freely available for possible modification and redistribution. Products include permission to use the source code, design documents, or content of the product. The open-source model is a decentralized software development model that encourages open collaboration. A main principle of open-source software development is peer production, with products such as source code, blueprints, and documentation freely available to the public. The open-source movement in software began as a response to the limitations of proprietary code. The model is used for projects such as in open-source appropriate technology, and open-source drug discovery. Open source promotes universal access via an open-source or free license to a product's design or blueprint, and universal redistribution of that design or blueprint. Before the phrase ''open source'' became widely adopted, developers and producers have used a variety of other terms. ''Open source'' gai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anne O'Tate
Anne O'Tate is a free, web-based application that analyses sets of records identified on PubMed, the bibliographic database of articles from over 5,500 biomedical journals worldwide. While PubMed has its own wide range of search options to identify sets of records relevant to a researchers query it lacks the ability to analyse these sets of records further, a process for which the terms text mining and drill down have been used. Anne O'Tate is able to perform such analysis and can process sets of up to 25,000 PubMed records. Description Once a set of articles has been identified using Anne O’Tate with its PubMed-like interface and search syntax, the set can be analysed and words and concepts mentioned in specific 'fields' (sections) of PubMed records can be displayed in order of frequency. ‘Fields’ which Anne O’Tate can display in this manner are: Topics (MeSH) This option may help to identify possible Medical Subject Headings (known as MeSH terms, but called ‘Topics� ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmaceutical Drug
A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy ( pharmacotherapy) is an important part of the medical field and relies on the science of pharmacology for continual advancement and on pharmacy for appropriate management. Drugs are classified in multiple ways. One of the key divisions is by level of control, which distinguishes prescription drugs (those that a pharmacist dispenses only on the order of a physician, physician assistant, or qualified nurse) from over-the-counter drugs (those that consumers can order for themselves). Another key distinction is between traditional small molecule drugs, usually derived from chemical synthesis, and biopharmaceuticals, which include recombinant proteins, vaccines, blood products used therapeutically (such as IVIG), gene therapy, monoclonal antibodies and cell therapy (for instance, stem cell therapi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as g ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Correlation
In statistics, correlation or dependence is any statistical relationship, whether causal or not, between two random variables or bivariate data. Although in the broadest sense, "correlation" may indicate any type of association, in statistics it usually refers to the degree to which a pair of variables are '' linearly'' related. Familiar examples of dependent phenomena include the correlation between the height of parents and their offspring, and the correlation between the price of a good and the quantity the consumers are willing to purchase, as it is depicted in the so-called demand curve. Correlations are useful because they can indicate a predictive relationship that can be exploited in practice. For example, an electrical utility may produce less power on a mild day based on the correlation between electricity demand and weather. In this example, there is a causal relationship, because extreme weather causes people to use more electricity for heating or cooling. H ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Arrowsmith (novel)
''Arrowsmith'' is a novel by American author Sinclair Lewis, first published in 1925. It won the 1926 Pulitzer Prize (which Lewis declined). Lewis was greatly assisted in its preparation by science writer Paul de Kruif, who received 25% of the royalties on sales, although Lewis was listed as the sole author. ''Arrowsmith'' is an early major novel dealing with the culture of science. It was written in the period after the reforms of medical education flowing from the Flexner Report on ''Medical Education in the United States and Canada: A Report to the Carnegie Foundation for the Advancement of Teaching'', 1910, which had called on medical schools in the United States to adhere to mainstream science in their teaching and research. The book was adapted by Hollywood as '' Arrowsmith'' in 1931, starring Ronald Colman and Helen Hayes. It was nominated for four Academy Awards, including Best Adapted Screenplay. Plot ''Arrowsmith'' tells the story of bright and scientifically mind ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Software
Software is a set of computer programs and associated software documentation, documentation and data (computing), data. This is in contrast to Computer hardware, hardware, from which the system is built and which actually performs the work. At the low level language, lowest programming level, executable code consists of Machine code, machine language instructions supported by an individual Microprocessor, processor—typically a central processing unit (CPU) or a graphics processing unit (GPU). Machine language consists of groups of Binary number, binary values signifying Instruction set architecture, processor instructions that change the state of the computer from its preceding state. For example, an instruction may change the value stored in a particular storage location in the computer—an effect that is not directly observable to the user. An instruction System call, may also invoke one of many Input/output, input or output operations, for example displaying some text on ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Illinois At Chicago
The University of Illinois Chicago (UIC) is a public research university in Chicago, Illinois. Its campus is in the Near West Side community area, adjacent to the Chicago Loop. The second campus established under the University of Illinois system, UIC is also the largest university in the Chicago metropolitan area, having more than 33,000 students enrolled in 16 colleges. It is classified among "R1: Doctoral Universities – Very high research activity." The roots of UIC can be traced to the establishment of the Chicago College of Pharmacy in 1859, which was joined in the 1800s by additional medical related schools. It began an undergraduate program toward the end of World War II, and developed its West side campus in the 1960s. In 1982, it consolidated the University of Illinois at Chicago Circle and the University of Illinois at the Medical Center into the present university. Today, the university has become a global leader for a number of subjects, such as nursing, pharmac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Magnesium
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a shiny gray metal having a low density, low melting point and high chemical reactivity. Like the other alkaline earth metals (group 2 of the periodic table) it occurs naturally only in combination with other elements and it almost always has an oxidation state of +2. It reacts readily with air to form a thin passivation coating of magnesium oxide that inhibits further corrosion of the metal. The free metal burns with a brilliant-white light. The metal is obtained mainly by electrolysis of magnesium salts obtained from brine. It is less dense than aluminium and is used primarily as a component in strong and lightweight alloys that contain aluminium. In the cosmos, magnesium is produced in large, aging stars by the sequential addition of three helium nuclei to a carbon nucleus. When such stars explode as supernovas, much of the magnesium is expelled into the interstellar medium wh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Migraine
Migraine (, ) is a common neurological disorder characterized by recurrent headaches. Typically, the associated headache affects one side of the head, is pulsating in nature, may be moderate to severe in intensity, and could last from a few hours to three days. Non-headache symptoms may include nausea, vomiting, and sensitivity to light, sound, or smell. The pain is generally made worse by physical activity during an attack,as PDF although regular may prevent future attacks. Up to one-third of people affected have |
.svg "Click for more on -> Software")
_(14592057920).jpg "Click for more on -> University Of Illinois At Chicago")
_1.jpg "Click for more on -> Migraine")