Apolipoprotein C-IV
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Apolipoprotein C-IV
Apolipoprotein C-IV, also known as apolipoprotein C4, is a protein that in humans is encoded by the ''APOC4'' gene. Function ''APOC4'' is a member of the apolipoprotein C In the field of molecular biology, apolipoprotein C is a family of four low molecular weight apolipoproteins, designated as C-I, C-II, C-III, and C-IV. These are surface components of chylomicrons, VLDL, and HDL. When an organism is in the fas ... gene family. It is expressed in the liver and has a predicted protein structure characteristic of the other genes in this family. ''APOC4'' is a 3.3-kb gene consisting of 3 exons and 2 introns; it is located 0.5 kb 5' to the ''APOC2'' gene. References External links * Further reading * * * * * * * * * * * * * * * * * * * Apolipoproteins {{gene-19-stub ...
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Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metabolic reactions, DNA replication, Cell signaling, responding to stimuli, providing Cytoskeleton, structure to cells and Fibrous protein, organisms, and Intracellular transport, transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the Nucleic acid sequence, nucleotide sequence of their genes, and which usually results in protein folding into a specific Protein structure, 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called pep ...
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Gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and non-coding genes. During gene expression (the synthesis of Gene product, RNA or protein from a gene), DNA is first transcription (biology), copied into RNA. RNA can be non-coding RNA, directly functional or be the intermediate protein biosynthesis, template for the synthesis of a protein. The transmission of genes to an organism's offspring, is the basis of the inheritance of phenotypic traits from one generation to the next. These genes make up different DNA sequences, together called a genotype, that is specific to every given individual, within the gene pool of the population (biology), population of a given species. The genotype, along with environmental and developmental factors, ultimately determines the phenotype ...
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Apolipoprotein C
In the field of molecular biology, apolipoprotein C is a family of four low molecular weight apolipoproteins, designated as C-I, C-II, C-III, and C-IV. These are surface components of chylomicrons, VLDL, and HDL. When an organism is in the fasting state, the C apolipoproteins are mainly associated with HDL. But during absorption of dietary fat, the C apolipoproteins preferentially redistribute to the surface of the triglyceride A triglyceride (from '' tri-'' and '' glyceride''; also TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. Triglycerides are the main constituents of body fat in humans and other vertebrates ...-rich chylomicrons and VLDL. References Apolipoproteins {{protein-stub ...
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