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Anticancer Fund
The Anticancer Fund (ACF) is a Belgian private not-for-profit foundation that provides evidence-based information for patients about cancers and therapies. History Officially established in 2013, the foundation has grown from Reliable Cancer Therapies (RCT), a non-profit organization established in 2009. RCT is still operational today, but the foundation has taken over many of its tasks as well as the goals. Activities The vision of the ACF is to expand the amount of possible treatment options for cancer. The mission of the Anticancer Fund is to cure all people who suffer from cancer. This is done on two levels: information and research. Information One of the main activities of the anticancer Fund is providing the public with scientifically accurate information regarding cancer and treatments. This includes information on the different types of cancer, treatments (both conventional and non-conventional) and other information related to cancer and therapies. The Anticancer Fund ...
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GcMAF
GcMAF (or Gc protein-derived macrophage activating factor) is a protein produced by modification of vitamin D-binding protein. Biochemically, GcMAF results from sequential Glycolysis, deglycosylation of the vitamin D-binding protein (the Gc protein), which is naturally promoted by lymphocytes (B cell, B and T cell, T cells). The resulting protein may be a macrophage activating factor (MAF). MAFs are lymphokines that control the expression of antigens on the surface of macrophages, and one of their functions is to make macrophages become Cytotoxicity, cytotoxic to tumors. False claims Since around 2008, GcMAF has been promoted as a cure for cancer, HIV, autism and other conditions. Three out of four of the original studies authored by Yamamoto (published between 2007 and 2009) were retractions in academic publishing, retracted by the scientific journals in which they were published in 2014, officially due to irregularities in the way institutional review board, ethical approva ...
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CUSP9
CUSP9 oordinated Undermining of Survival Pathsis one of several cancer treatment protocols using re-purposed older drugs to interfere with cancer cell's growth signaling rather than directly killing them with cytotoxic drugs. CUSP9 is a treatment specifically targeted to glioblastoma that adds to a traditional cancer cell killing drug, temozolomide, nine older, non-cytotoxic drugs to block growth factors that enhance or drive glioblastoma growth - aprepitant blocks NK-1, auranofin inhibits thioredoxin reductase, captopril inhibits angiotensin converting enzyme, celecoxib blocks cyclooxygenase-2, disulfiram blocks aldehyde dehydrogenase, itraconazole blocks Hedgehog signaling, minocycline inhibits metalloproteinase-2 and -9, quetiapine inhibits RANKL, sertraline inhibits translation-controlled tumor protein CTP These targets have been shown to be active in promoting glioblastoma growth. The current version, CUSP9v3, uses continuous daily very low dose temozolomide with aprepitan ...
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Diclofenac
Diclofenac, sold under the brand name Voltaren, among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammatory diseases such as gout. It is taken by mouth or rectally in a suppository, used by injection, or applied to the skin. Improvements in pain last for as much as eight hours. It is also available in combination with misoprostol in an effort to decrease stomach problems. Common side effects include abdominal pain, gastrointestinal bleeding, nausea, dizziness, headache, and swelling. Serious side effects may include heart disease, stroke, kidney problems, and stomach ulceration. Use is not recommended in the third trimester of pregnancy. It is likely safe during breastfeeding. Diclofenac is believed to work by decreasing the production of prostaglandins, like other drugs in this class. Diclofenac was patented in 1965 by J.R. Geigy AG; it came into medical use in the United States in 1988. It is available as a generic medicatio ...
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Nitroglycerin
Nitroglycerin (NG), (alternative spelling of nitroglycerine) also known as trinitroglycerin (TNG), nitro, glyceryl trinitrate (GTN), or 1,2,3-trinitroxypropane, is a dense, colorless, oily, explosive liquid most commonly produced by nitrating glycerol with white fuming nitric acid under conditions appropriate to the formation of the nitric acid ester. Chemically, the substance is an organic nitrate compound rather than a nitro compound, but the traditional name is retained. Invented in 1847 by Ascanio Sobrero, nitroglycerin has been used ever since as an active ingredient in the manufacture of explosives, namely dynamite, and as such it is employed in the construction, demolition, and mining industries. Since the 1880s, it has been used by militaries as an active ingredient and gelatinizer for nitrocellulose in some solid propellants such as cordite and ballistite. It is a major component in double-based smokeless propellants used by reloaders. Combined with nitrocell ...
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