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Anne McLaren
Dame Anne Laura Dorinthea McLaren, (26 April 1927 – 7 July 2007) was a British scientist who was a leading figure in developmental biology. She paved the way for women in science and her work helped lead to human in vitro fertilisation (IVF). She left an enduring legacy marked by her research and ethical contributions to the field. She received many honors for her contributions to science, including election as fellow of the Royal Society. Early life McLaren was born into a privileged family with notable lineage, as the fourth of five children. She was the daughter of Sir Henry McLaren, 2nd Baron Aberconway, a former Liberal MP, and Christabel Mary Melville MacNaghten. She was born in London and spent her early childhood there, attending private schools. At the age of seven she appeared in the film version of H. G. Wells' novel '' Things to Come'', released in 1936. At the outbreak of World War II, she was 12 years old and her family moved to their estate at Bodnant, ...
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The Honourable
''The Honourable'' (Commonwealth English) or ''The Honorable'' (American English; American and British English spelling differences#-our, -or, see spelling differences) (abbreviation: ''Hon.'', ''Hon'ble'', or variations) is an honorific Style (manner of address), style that is used as a prefix before the names or titles of certain people, usually with official governmental or diplomatic positions. Use by governments International diplomacy In international diplomatic relations, representatives of foreign states are often styled as ''The Honourable''. Deputy chiefs of mission, , consuls-general, consuls and honorary consuls are always given the style. All heads of consular posts, whether they are honorary or career postholders, are accorded the style according to the State Department of the United States. However, the style ''Excellency'' instead of ''The Honourable'' is used for ambassadors and high commissioners only. Africa Democratic Republic of the Congo In the Democrati ...
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Cambridge
Cambridge ( ) is a List of cities in the United Kingdom, city and non-metropolitan district in the county of Cambridgeshire, England. It is the county town of Cambridgeshire and is located on the River Cam, north of London. As of the 2021 United Kingdom census, the population of the City of Cambridge was 145,700; the population of the wider built-up area (which extends outside the city council area) was 181,137. (2021 census) There is archaeological evidence of settlement in the area as early as the Bronze Age, and Cambridge became an important trading centre during the Roman Britain, Roman and Viking eras. The first Town charter#Municipal charters, town charters were granted in the 12th century, although modern city status was not officially conferred until 1951. The city is well known as the home of the University of Cambridge, which was founded in 1209 and consistently ranks among the best universities in the world. The buildings of the university include King's College Chap ...
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Blastocyst
The blastocyst is a structure formed in the early embryonic development of mammals. It possesses an inner cell mass (ICM) also known as the ''embryoblast'' which subsequently forms the embryo, and an outer layer of trophoblast cells called the trophectoderm. This layer surrounds the inner cell mass and a fluid-filled cavity or lumen known as the blastocoel. In the late blastocyst, the trophectoderm is known as the trophoblast. The trophoblast gives rise to the chorion and amnion, the two fetal membranes that surround the embryo. The placenta derives from the embryonic chorion (the portion of the chorion that develops villi) and the underlying uterine tissue of the mother. The corresponding structure in non-mammalian animals is an undifferentiated ball of cells called the blastula. In humans, blastocyst formation begins about five days after fertilization when a fluid-filled cavity opens up in the morula, the early embryonic stage of a ball of 16 cells. The blastocyst ...
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John D
John is a common English name and surname: * John (given name) * John (surname) John may also refer to: New Testament Works * Gospel of John, a title often shortened to John * First Epistle of John, often shortened to 1 John * Second Epistle of John, often shortened to 2 John * Third Epistle of John, often shortened to 3 John People * John the Baptist (died ), regarded as a prophet and the forerunner of Jesus Christ * John the Apostle (died ), one of the twelve apostles of Jesus Christ * John the Evangelist, assigned author of the Fourth Gospel, once identified with the Apostle * John of Patmos, also known as John the Divine or John the Revelator, the author of the Book of Revelation, once identified with the Apostle * John the Presbyter, a figure either identified with or distinguished from the Apostle, the Evangelist and John of Patmos Other people with the given name Religious figures * John, father of Andrew the Apostle and Saint Peter * Pope Jo ...
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Nature (journal)
''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features Peer review, peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature. ''Nature'' was one of the world's most cited scientific journals by the Science Edition of the 2022 ''Journal Citation Reports'' (with an ascribed impact factor of 50.5), making it one of the world's most-read and most prestigious academic journals. , it claimed an online readership of about three million unique readers per month. Founded in the autumn of 1869, ''Nature'' was first circulated by Norman Lockyer and Alexander MacMillan (publisher), Alexander MacMillan as a public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the j ...
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Superpregnancy
Superfetation (also spelled superfoetation – see fetus) is the simultaneous occurrence of more than one stage of developing offspring in the same animal. In mammals, it manifests as the formation of an embryo from a subsequent menstrual cycle, while another embryo or fetus is already present in the uterus. When two separate instances of fertilisation occur during the same menstrual cycle, it is known as superfecundation. Humans While proposed cases of superfetation have been reported in humans, the existence of this phenomenon in humans has been deemed unlikely. Better explanations include differential growth between twins due to various reasons, such as twin-to-twin transfusion syndrome. Artificially-induced superfetation has been demonstrated, although only up to a short period after insemination. A 2008 French study found evidence to suggest that superfetation is a reality for humans, but that it is so rare that there have been fewer than 10 recorded cases in the world. In ...
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Controlled Ovarian Hyperstimulation
Controlled ovarian hyperstimulation is a technique used in assisted reproduction involving the use of fertility medications to induce ovulation by multiple ovarian follicles. These multiple follicles can be taken out by oocyte retrieval (egg collection) for use in ''in vitro'' fertilisation (IVF), or be given time to ovulate, resulting in superovulation which is the ovulation of a larger-than-normal number of eggs, generally in the sense of at least two. When ovulated follicles are fertilised ''in vivo'', whether by natural or artificial insemination, there is a very high risk of a multiple pregnancy. In this article, unless otherwise specified, hyperstimulation will refer to hyperstimulation as part of IVF. In contrast, ovulation induction is ovarian stimulation without subsequent IVF, with the aim of developing one or two ovulatory follicles. Procedure Response prediction Response predictors determine the protocol for ovulation suppression as well as dosage of medicatio ...
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Lumbar Vertebrae
The lumbar vertebrae are located between the thoracic vertebrae and pelvis. They form the lower part of the back in humans, and the tail end of the back in quadrupeds. In humans, there are five lumbar vertebrae. The term is used to describe the anatomy of humans and quadrupeds, such as horses, pigs, or cattle. These bones are found in particular cuts of meat, including tenderloin or sirloin steak. Human anatomy In human anatomy, the five vertebrae are between the rib cage and the pelvis. They are the largest segments of the vertebral column and are characterized by the absence of the foramen transversarium within the transverse process (since it is only found in the cervical region) and by the absence of facets on the sides of the body (as found only in the thoracic region). They are designated L1 to L5, starting at the top. The lumbar vertebrae help support the weight of the body, and permit movement. General characteristics The adjacent figure depicts the general cha ...
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Royal Veterinary College
The Royal Veterinary College (informally the RVC) is a veterinary school located in London and a member institution of the federal University of London. The RVC was founded in 1791 and joined the University of London in 1949. It is the oldest and largest veterinary school in the United Kingdom, and one of only 11 in the country where students can study to become a vet. History 18th century The Veterinary College of London was founded in 1791 by a group led by Granville Penn, a grandson of William Penn, following the foundation of the first veterinary college in Europe in Lyon, France, in 1762. The promoters wished to select a site close to the metropolis, but far enough away to minimise the temptations open to the students, who were all men. Earl Camden was just then making arrangements to develop some fields he owned to the north of London, and he replied to the college's newspaper advertisement for a suitable site with an offer to sell it some of his land. The site was rura ...
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Drosophila
''Drosophila'' (), from Ancient Greek δρόσος (''drósos''), meaning "dew", and φίλος (''phílos''), meaning "loving", is a genus of fly, belonging to the family Drosophilidae, whose members are often called "small fruit flies" or pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit. They should not be confused with the Tephritidae, a related family, which are also called fruit flies (sometimes referred to as "true fruit flies"); tephritids feed primarily on unripe or ripe fruit, with many species being regarded as destructive agricultural pests, especially the Mediterranean fruit fly. One species of ''Drosophila'' in particular, ''Drosophila melanogaster'', has been heavily used in research in genetics and is a common model organism in developmental biology. The terms "fruit fly" and "''Drosophila''" are often used synonymously with ''D. melanogaster'' in modern biological literatur ...
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University College London
University College London (Trade name, branded as UCL) is a Public university, public research university in London, England. It is a Member institutions of the University of London, member institution of the Federal university, federal University of London, and is the second-largest list of universities in the United Kingdom by enrolment, university in the United Kingdom by total enrolment and the largest by postgraduate enrolment. Established in 1826 as London University (though without university degree-awarding powers) by founders who were inspired by the radical ideas of Jeremy Bentham, UCL was the first university institution to be established in London, and the first in England to be entirely secular and to admit students regardless of their religion. It was also, in 1878, among the first university colleges to admit women alongside men, two years after University College, Bristol, had done so. Intended by its founders to be Third-oldest university in England debate ...
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Master Of Arts (Oxbridge)
In the universities of Oxford, Cambridge, and Dublin, Bachelors of Arts (BAs) are promoted to the rank of Master of Arts (MA), typically upon application after three or four years after graduation. No further examination or study is required for this promotion, which is a mark of seniority rather than an additional postgraduate qualification. According to the formula of '' ad eundem gradum'', the graduates of the Universities of Oxford, Cambridge, and Dublin are eligible to apply to incorporate and be granted equivalent academic degrees at any of the other two universities, provided that they wish to register for such a degree or are members of the academic staff; they also pay a required fee. The example of the " Steamboat ladies" (roughly 720 women graduates of both Oxford and Cambridge who received Dublin academic degrees) is one of the most popular incidents of incorporation. While not an earned degree, both the original degree(s) and the incorporated ''ad eundem'' degree(s) ...
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