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Anne Haney Cross
Anne Cross (born c. February 27, 1956) is an American neurologist and neuroimmunologist and the Section Head of Neuroimmunology at Washington University School of Medicine in St. Louis, Missouri. Cross holds the Manny and Rosalyn Rosenthal–Dr. John L. Trotter Endowed Chair in Neuroimmunology at Washington University in St. Louis School of Medicine and co-directs the John L Trotter Multiple Sclerosis Clinic at Barnes-Jewish Hospital. Cross is a leader in the field of neuroimmunology and was the first to discover the role of B cells in the pathogenesis of multiple sclerosis (MS) in animals and then in humans. Cross now develops novel imaging techniques to observe inflammation and demyelination in the central nervous systems of MS patients for diagnosis and disease management. Early life and education Cross grew up in Mobile, Alabama. Cross pursued her undergraduate degree at the University of South Alabama in Mobile. She majored in chemistry and graduated summa cum laude with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mobile, Alabama
Mobile ( , ) is a city and the county seat of Mobile County, Alabama, United States. The population was 187,041 at the 2020 United States census, 2020 census. After a successful vote to annex areas west of the city limits in July 2023, Mobile's population increased to 204,689 residents, making it the List of municipalities in Alabama, second-most populous city in Alabama. Mobile is the principal municipality of the Mobile metropolitan area. Alabama's only saltwater port, Mobile is located on the Mobile River at the head of Mobile Bay on the north-central Gulf Coast of the United States, Gulf Coast. The Port of Mobile has always played a key role in the economic health of the city, beginning with the settlement as an important trading center between the French colonization of the Americas, French colonists and Native Americans in the United States, Native Americans, down to its current role as the 12th-largest port in the United States.Drechsel, Emanuel. ''Mobilian Jargon: Lin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
George Washington University School Of Medicine & Health Sciences
The George Washington University School of Medicine and Health Sciences (abbreviated as GW Medical School, GW Medicine, or SMHS) is the professional medical school of the George Washington University, in Washington, D.C. SMHS is one of the most selective medical schools in the United States based on the number of applicants. It was the eleventh medical school to open in what is now the United States, and is the seventh-oldest medical school in the country that is still operating. Rankings ''U.S. News & World Report'' ranks GW Medicine as having the third best physician assistant program, the 29th best physical therapy program, as tied for the 58th best research medical school, and as tied for the 68th best primary care medical school in the United States. The George Washington University Hospital has routinely served the medical needs of presidents of the United States and members of Congress, members of the U.S. Congress. GW Medicine is regularly one of the most selective medic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Laura Piccio
Laura may refer to: People and fictional characters * Laura (given name), including lists of people and fictional characters with the name * Laura, muse of Petrarch's poetry * Laura, the British code name for the World War I Belgian spy Marthe Cnockaert Places Australia * Laura, Queensland, a town on the Cape York Peninsula * Laura, South Australia, a town * Laura Bay, a bay on Eyre Peninsula * Laura River (Queensland) * Laura River (Western Australia) Italy * Laura (Capaccio), a village of the municipality of Capaccio, Campania * Laura, Crespina Lorenzana, a village in Tuscany United States * Laura, Illinois, an unincorporated community * Laura, Kentucky, an unincorporated community * Laura, Missouri, an unincorporated community * Laura, Ohio, a village Elsewhere * Laura, Saskatchewan, Canada, a hamlet * Laura, Marshall Islands, a town * Laura, Silesian Voivodeship, Poland, a village * Laura River (Romania) * 467 Laura, an asteroid Arts and entertainment Art * ''Laura ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diffusion MRI
Diffusion-weighted magnetic resonance imaging (DWI or DW-MRI) is the use of specific MRI sequences as well as software that generates images from the resulting data that uses the diffusion of water molecules to generate contrast (vision), contrast in MR images. It allows the mapping of the diffusion process of molecules, mainly water, in biological tissues, in vivo and non-invasively. Molecular diffusion in tissues is not random, but reflects interactions with many obstacles, such as macromolecules, fibers, and Biological membrane, membranes. Water molecule diffusion patterns can therefore reveal microscopic details about tissue architecture, either normal or in a diseased state. A special kind of DWI, diffusion tensor imaging (DTI), has been used extensively to map white matter tractography in the brain. Introduction In diffusion weighted imaging (DWI), the intensity of each image element (voxel) reflects the best estimate of the rate of water diffusion at that location. Because ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CD20
B-lymphocyte antigen CD20 or CD20 is B lymphocyte cell-surface molecule. It is a 33-37 kDa non-glycosylated protein. CD20 is expressed on the surface of B-cells from the pre-B phase, the expression is lost in terminally differentiated plasma cells. CD20 is used as a therapeutical target of B-cell malignancies and autoimmune diseases. Gene In humans CD20 is encoded by the ''MS4A1'' gene localized to 11q12. The gene is 16 kbp long and consists of 8 exons. There are at least 3 mRNA transcripts (resulting from alternative splicing), that are all translated into an identical full-length CD20 protein product. Variants 1 and 2 are poorly translated due to inhibitory upstream open reading frames and stem-loop structures within their 5' untranslated regions. The relative abundance of translation-competent variant 3, as opposed to the poorly translated variants 1 and 2, may be a key determinant of CD20 levels in normal and malignant human B cells and their responses to CD20-d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rituximab
Rituximab, sold under the brand name Rituxan among others, is a monoclonal antibody medication used to treat certain autoimmune diseases and types of cancer. It is used for non-Hodgkin lymphoma, chronic lymphocytic leukemia (in children and adults, but not recommended in elderly patients), rheumatoid arthritis, granulomatosis with polyangiitis, idiopathic thrombocytopenic purpura, pemphigus vulgaris, myasthenia gravis and Epstein–Barr virus-positive mucocutaneous ulcers. It is given by slow intravenous infusion (injected slowly through an IV line). The most common side effects with intravenous infusions are reactions related to the infusion (such as fever, chills and shivering) while most common serious side effects are infusion reactions, infections and heart-related problems. Similar side effects are seen when it is injected under the skin, with the exception of reactions around the injections site (pain, swelling and rash), which occur more frequently with the skin inject ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Experimental Autoimmune Encephalomyelitis
Experimental autoimmune encephalomyelitis, sometimes experimental allergic encephalomyelitis (EAE), is an animal model of brain inflammation. It is an inflammatory demyelinating disease of the central nervous system (CNS). It is mostly used with rodents and is widely studied as an animal model of the human CNS demyelinating diseases, including multiple sclerosis (MS) and acute disseminated encephalomyelitis (ADEM). EAE is also the prototype for T-cell-mediated autoimmune disease in general. EAE development was motivated by observations during the convalescence from viral diseases by Thomas M. Rivers, D. H. Sprunt and G. P. Berry in 1933. Their findings upon a transfer of inflamed patient tissue to primates was published in the '' Journal of Experimental Medicine''. An acute monophasic illness, it has been suggested that EAE is far more similar to ADEM than to MS. Types of EAE EAE can be induced in a number of species, including mice, rats, guinea pigs, rabbits and primates. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Bronx
The Bronx ( ) is the northernmost of the five Boroughs of New York City, boroughs of New York City, coextensive with Bronx County, in the U.S. state of New York (state), New York. It shares a land border with Westchester County, New York, Westchester County to its north; to its south and west, the New York City borough of Manhattan is across the Harlem River; and to its south and east is the borough of Queens, across the East River. The Bronx, the only New York City borough not primarily located on an island, has a land area of and a population of 1,472,654 at the 2020 United States census, 2020 census. It has the fourth-largest area, fourth-highest population, and third-highest population density of the boroughs.New York State Department of Health''Population, Land Area, and Population Density by County, New York State – 2010'' retrieved on August 8, 2015. The Bronx is divided by the Bronx River into a hillier section in the West Bronx, west, and a flatter East Bronx, easte ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Albert Einstein College Of Medicine
The Albert Einstein College of Medicine is a Private university, private medical school in New York City. Founded in 1953, Einstein is an independent degree-granting institution within the Montefiore Einstein Health System. Einstein hosts Doctor of Medicine, MD, Doctor of Philosophy, PhD, and masters programs. Admission to its MD program is highly selective, with an acceptance rate of 1.85% in 2024. Joint masters are offered with the City University of New York and Yeshiva University's Benjamin N. Cardozo School of Law, Cardozo School of Law. Einstein is also home to one of the first three Medical Scientist Training Programs inaugurated in 1964. This joint MD/PhD program has received continuous funding from the National Institutes of Health. Planning for the college was initiated by Yeshiva University President Samuel Belkin in 1945. Physicist Albert Einstein, who noted that the college would be unique as it would provide medical training to "students of all creeds and races" ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Multiple Sclerosis Society
The National Multiple Sclerosis Society (NMSS) is an American nonprofit organization founded in 1946. It is an organization dedicated to supporting individuals affected by multiple sclerosis (MS) and funding research to find a cure for the disease. They provide resources, support services, advocacy efforts, and educational programs to improve the lives of people with MS and their families. History The National Multiple Sclerosis Society (NMSS) was founded in New York City as the Association for Advancement of Research on Multiple Sclerosis on March 11, 1946 by Sylvia Lawry, a lawyer seeking a cure for her brother, Bernard, who suffered from multiple sclerosis. Recognizing the absence of any existing foundation or organization aiding individuals with (MS), Ms. Lawry established NMSS. With chapters spanning the United States, the organization funds research, advocates for social and political change, offers educational resources, and sponsors services that help people with multipl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuropathology
Neuropathology is the study of disease of nervous system tissue, usually in the form of either small surgical biopsies or whole-body autopsies. Neuropathologists usually work in a department of anatomic pathology, but work closely with the clinical disciplines of neurology, and neurosurgery, which often depend on neuropathology for a diagnosis. Neuropathology also relates to forensic pathology because brain disease or brain injury can be related to cause of death. Neuropathology should not be confused with neuropathy, which refers to disorders of the nerves themselves (usually in the peripheral nervous system) rather than the tissues. In neuropathology, the branches of the specializations of nervous system as well as the tissues come together into one field of study. Methodology The work of the neuropathologist consists largely of examining autopsy or biopsy tissue from the brain and spinal cord to aid in diagnosis of disease. In addition to brain and spinal cord, tissues of th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Memphis, Tennessee
Memphis is a city in Shelby County, Tennessee, United States, and its county seat. Situated along the Mississippi River, it had a population of 633,104 at the 2020 United States census, 2020 census, making it the List of municipalities in Tennessee, second-most populous city in Tennessee, the fifth-most populous in the Southeastern United States, Southeast, and the List of United States cities by population, 28th-most populous in the nation. Memphis is the largest city proper on the Mississippi River and anchors the Memphis metropolitan area that includes parts of Arkansas and Mississippi, the Metropolitan statistical area, 45th-most populous metropolitan area in the U.S. with 1.34 million residents. European exploration of the area began with Spanish conquistador Hernando de Soto in 1541. Located on the high Chickasaw Bluffs, the site offered natural protection from Mississippi River flooding and became a contested location in the colonial era. Modern Memphis was founded in 181 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
