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Angelo Azzi
Angelo Azzi is an Italian and Swiss biochemist, author and academic serving as a Professor Emeritus in the Institute of Biochemistry and Molecular Medicine at the University of Bern and Adjunct Faculty Member at Tufts University. Azzi's work focuses on the biochemistry of enzymes, gene regulation, and metabolism, with an emphasis on vitamin E ( ''alpha''-tocopherol), antioxidants, and signaling pathways involving protein kinase C and diacylglycerol kinase. He has received awards, including the 2002 Vitamin Prize from the Society for Applied Vitamin Research, the Society of Free Radicals' Lifetime Achievement Award in 2014, the International Union of Biochemistry and Molecular Biology Distinguished Service Award in 2016, and the Nencki Award from the Nencki Institute of Experimental Biology in 2016. Azzi is a Foreign Member of the Polish Academy of Sciences and a Lifetime Honorary Member of the Oxygen Club of California. He also holds editorial roles, including Editor-in-Chief of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Modena
Modena (, ; ; ; ; ) is a city and ''comune'' (municipality) on the south side of the Po Valley, in the Province of Modena, in the Emilia-Romagna region of northern Italy. It has 184,739 inhabitants as of 2025. A town, and seat of an archbishop, it is known for its car industry since the factories of the famous Italian upper-class sports car makers Ferrari, De Tomaso, Lamborghini, Pagani Automobili, Pagani and Maserati are, or were, located there and all, except Lamborghini, (having their factory in Sant'Agata Bolognese), have headquarters in the city or nearby. One of Ferrari's cars, the Ferrari 360, 360 Modena, was named after the town itself. Ferrari's production plant and Formula One team Scuderia Ferrari are based in Maranello south of the city. The University of Modena, founded in 1175 and expanded by Francesco II d'Este in 1686, focuses on economics, medicine and law, and is the second oldest :wikt:athenaeum, athenaeum in Italy. Italian military officers are trained at ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diacylglycerol Kinase
Diacylglycerol kinase (DGK or DAGK) is a family of enzymes that catalyzes the conversion of diacylglycerol (DAG) to phosphatidic acid (PA), utilizing ATP as a source of the phosphate. In non-stimulated cells, DGK activity is low, allowing DAG to be used for glycerophospholipid biosynthesis, but on receptor activation of the phosphoinositide pathway, DGK activity increases, driving the conversion of DAG to PA. As both lipids are thought to function as bioactive lipid signaling molecules with distinct cellular targets, DGK therefore occupies an important position, effectively serving as a switch by terminating the signalling of one lipid while simultaneously activating signalling by another. In bacteria, DGK is very small (13 to 15 kDa) membrane protein which seems to contain three transmembrane domains. The best conserved region is a stretch of 12 residues which are located in a cytoplasmic loop between the second and third transmembrane domains. Some Gram-positive bacteria ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biochemists
Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and cell parts. The word "biochemist" is a portmanteau of "biological chemist." Biochemists also research how certain chemical reactions happen in cells and tissues and observe and record the effects of products in food additives and medicines. Biochemist researchers focus on playing and constructing research experiments, mainly for developing new products, updating existing products and analyzing said products. It is also the responsibility of a biochemist to present their research findings and create grant proposals to obtain funds for future research. Biochemists study aspects of the immune system, the expressions of genes, isolating, analyzing, and synthesizing different products, mutations that lead to cancers, and manage laboratory teams and monitor laboratory work. Biochemists also have to have ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1939 Births
This year also marks the start of the World War II, Second World War, the largest and deadliest conflict in human history. Events Events related to World War II have a "WWII" prefix. January * January 1 ** Coming into effect in Nazi Germany of: *** The Protection of Young Persons Act (Germany), Protection of Young Persons Act, passed on April 30, 1938, the Working Hours Regulations. *** The small businesses obligation to maintain adequate accounting. *** The Jews name change decree. ** With his traditional call to the New Year in Nazi Germany, Führer and Reich Chancellor Adolf Hitler addresses the members of the National Socialist German Workers' Party (NSDAP). ** The Hewlett-Packard technology and scientific instruments manufacturing company is founded by Bill Hewlett and David Packard, in a garage in Palo Alto, California, considered the birthplace of Silicon Valley. ** Philipp Etter takes over as President of the Swiss Confederation. ** The Third Soviet Five Year P ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UNESCO
The United Nations Educational, Scientific and Cultural Organization (UNESCO ) is a List of specialized agencies of the United Nations, specialized agency of the United Nations (UN) with the aim of promoting world peace and International security, security through international cooperation in education, arts, sciences and culture. It has 194 Member states of UNESCO, member states and 12 associate members, as well as partners in the Non-governmental organization, non-governmental, Intergovernmental organization, intergovernmental and private sector. Headquartered in Paris, France, UNESCO has 53 regional field offices and 199 National Commissions for UNESCO, national commissions. UNESCO was founded in 1945 as the successor to the League of Nations' International Committee on Intellectual Cooperation.English summary). UNESCO's founding mission, which was shaped by the events of World War II, is to advance peace, sustainable development and human rights by facilitating collaboratio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Switzerland
Switzerland, officially the Swiss Confederation, is a landlocked country located in west-central Europe. It is bordered by Italy to the south, France to the west, Germany to the north, and Austria and Liechtenstein to the east. Switzerland is geographically divided among the Swiss Plateau, the Swiss Alps, Alps and the Jura Mountains, Jura; the Alps occupy the greater part of the territory, whereas most of the country's Demographics of Switzerland, 9 million people are concentrated on the plateau, which hosts List of cities in Switzerland, its largest cities and economic centres, including Zurich, Geneva, and Lausanne. Switzerland is a federal republic composed of Cantons of Switzerland, 26 cantons, with federal authorities based in Bern. It has four main linguistic and cultural regions: German, French, Italian and Romansh language, Romansh. Although most Swiss are German-speaking, national identity is fairly cohesive, being rooted in a common historical background, shared ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bern
Bern (), or Berne (), ; ; ; . is the ''de facto'' Capital city, capital of Switzerland, referred to as the "federal city".; ; ; . According to the Swiss constitution, the Swiss Confederation intentionally has no "capital", but Bern has governmental institutions such as the Federal Assembly (Switzerland), Federal Assembly and Federal Council (Switzerland), Federal Council. However, the Federal Supreme Court of Switzerland, Federal Supreme Court is in Lausanne, the Federal Criminal Court of Switzerland, Federal Criminal Court is in Bellinzona and the Federal Administrative Court (Switzerland), Federal Administrative Court and the Federal Patent Court (Switzerland), Federal Patent Court are in St. Gallen, exemplifying the federal nature of the Confederation. With a population of about 146,000 (), Bern is the List of cities in Switzerland, fifth-most populous city in Switzerland, behind Zürich, Geneva, Basel and Lausanne. The Bern agglomeration, which includes 36 municipalities ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Pennsylvania
The University of Pennsylvania (Penn or UPenn) is a Private university, private Ivy League research university in Philadelphia, Pennsylvania, United States. One of nine colonial colleges, it was chartered in 1755 through the efforts of founder and first president Benjamin Franklin, who had advocated for an educational institution that trained leaders in academia, commerce, and public service. The university has four undergraduate schools and 12 graduate and professional schools. Schools enrolling undergraduates include the College of Arts and Sciences, the University of Pennsylvania School of Engineering and Applied Science, School of Engineering and Applied Science, the Wharton School, and the University of Pennsylvania School of Nursing, School of Nursing. Among its graduate schools are its University of Pennsylvania Law School, law school, whose first professor, James Wilson (Founding Father), James Wilson, helped write the Constitution of the United States, U.S. Cons ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Bristol
The University of Bristol is a public university, public research university in Bristol, England. It received its royal charter in 1909, although it can trace its roots to a Merchant Venturers' school founded in 1595 and University College, Bristol, which had been in existence since 1876. Bristol Medical School, founded in 1833, was merged with the University College in 1893, and later became the university's school of medicine. The university is organised into #Academic structure, six academic faculties composed of multiple schools and departments running over 200 undergraduate courses, largely in the Tyndalls Park area of the city. It had a total income of £1.06 billion in 2023–24, of which £294.1 million was from research grants and contracts, with an expenditure of £768.7 million. It is the largest independent employer in Bristol. Current academics include 23 fellows of the Academy of Medical Sciences, 13 fellows of the British Academy, 43 fellows of the Academy of Soc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mitochondrial Permeability Transition Pore
The mitochondrial permeability transition pore (mPTP or MPTP; also referred to as PTP, mTP, or MTP) is a protein pore complex that forms in the inner mitochondrial membrane under certain pathological conditions such as traumatic brain injury, ischemia, and stroke. Opening of the pore causes an increase in the permeability of the mitochondrial membrane to solutes with a molecular mass less than 1,500 daltons, leading to loss of membrane potential, swelling of the organelle, rupture of the outer membrane, and eventual cell death. The mPTP is thought to be regulated by multiple mitochondrial proteins. Historically, Cyclophilin D and the TSPO (formerly the peripheral benzodiazepine receptor) have been considered central components. In 2025, the AAA+ ATPase protein ATAD3A was identified as a novel upstream regulator of mPTP opening. Loss of ATAD3A was shown to prevent calcium-induced pore formation and render mitochondria insensitive to cyclosporin A, suggesting it acts upstream of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mitochondrion
A mitochondrion () is an organelle found in the cell (biology), cells of most eukaryotes, such as animals, plants and fungi. Mitochondria have a double lipid bilayer, membrane structure and use aerobic respiration to generate adenosine triphosphate (ATP), which is used throughout the cell as a source of chemical energy. They were discovered by Albert von Kölliker in 1857 in the voluntary muscles of insects. The term ''mitochondrion'', meaning a thread-like granule, was coined by Carl Benda in 1898. The mitochondrion is popularly nicknamed the "powerhouse of the cell", a phrase popularized by Philip Siekevitz in a 1957 ''Scientific American'' article of the same name. Some cells in some multicellular organisms lack mitochondria (for example, mature mammalian red blood cells). The multicellular animal ''Henneguya zschokkei, Henneguya salminicola'' is known to have retained mitochondrion-related organelles despite a complete loss of their mitochondrial genome. A large number ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecular Aspects Of Medicine
''Molecular Aspects of Medicine'' is a bimonthly peer-reviewed medical journal covering molecular medicine. It is published by Elsevier on behalf of the International Union of Biochemistry and Molecular Biology The International Union of Biochemistry and Molecular Biology (IUBMB) is an international non-governmental organisation concerned with biochemistry and molecular biology. Formed in 1955 as the International Union of Biochemistry (IUB), the union .... Abstracting and indexing The journal is abstracted and indexed in: Article categories The journal publishes only invited review articles. External links * General medical journals Elsevier academic journals Hybrid open access journals {{General-medical-journal-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
