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Amazon Malaria Initiative
The Amazon Malaria Initiative (AMI) was a regional program that was created in 2001 by several countries sharing the Amazon basin with technical support from PAHO/WHO and financial support from the U.S. Agency for International Development (USAID), and managed by USAID/Peru as part of its South American Regional Infectious Disease Program (SARI). The initiative used a multi-pronged approach to achieve the overall aims of preventing and controlling malaria and reducing malaria-related morbidity and mortality in countries of the Americas. AMI priorities for malaria prevention are as follows, diagnosis and treatment, drug resistance and epidemiological surveillance, vector control, pharmaceutical management, quality of medicines, communication and networking. History The rationale for creating AMI was the need to provide and invest in targeted activities to improve malaria control in the Amazon basin countries where 88% of malaria cases in Latin America and the Caribbean are repo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Malaria
Malaria is a Mosquito-borne disease, mosquito-borne infectious disease that affects vertebrates and ''Anopheles'' mosquitoes. Human malaria causes Signs and symptoms, symptoms that typically include fever, Fatigue (medical), fatigue, vomiting, and headaches. In severe cases, it can cause jaundice, Epileptic seizure, seizures, coma, or death. Symptoms usually begin 10 to 15 days after being bitten by an infected ''Anopheles'' mosquito. If not properly treated, people may have recurrences of the disease months later. In those who have recently survived an infection, reinfection usually causes milder symptoms. This partial Immunity (medical), resistance disappears over months to years if the person has no continuing exposure to malaria. The mosquitoes themselves are harmed by malaria, causing reduced lifespans in those infected by it. Malaria is caused by protozoa, single-celled microorganisms of the genus ''Plasmodium''. It is spread exclusively through bites of infected female ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Central American
Central America is a Subregion#North America, subregion of North America. Its political boundaries are defined as bordering Mexico to the north, Colombia to the southeast, the Caribbean to the east, and the Pacific Ocean to the southwest. Central America is usually defined as consisting of seven countries: Belize, Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua, and Panama. Within Central America is the Mesoamerican biodiversity hotspot, which extends from southern Mexico to southeastern Panama. Due to the presence of several active fault, active geologic faults and the Central America Volcanic Arc, there is a high amount of seismic activity in the region, such as volcanic eruptions and earthquakes, which has resulted in death, injury, and property damage. Most of Central America falls under the Isthmo-Colombian Area, Isthmo-Colombian cultural area. Before the Spanish expedition of Christopher Columbus' voyages to the Americas, hundreds of indigenous peoples made thei ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Centers For Disease Control And Prevention
The Centers for Disease Control and Prevention (CDC) is the National public health institutes, national public health agency of the United States. It is a Federal agencies of the United States, United States federal agency under the United States Department of Health and Human Services, Department of Health and Human Services (HHS), and is headquartered in Atlanta, Georgia. The CDC's current nominee for director is Susan Monarez. She became acting director on January 23, 2025, but stepped down on March 24, 2025 when nominated for the director position. On May 14, 2025, Robert F. Kennedy Jr. stated that lawyer Matthew Buzzelli is acting CDC director. However, the CDC web site does not state the acting director's name. The agency's main goal is the protection of public health and safety through the control and prevention of disease, injury, and disability in the US and worldwide. The CDC focuses national attention on developing and applying disease control and prevention. It e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antimalarial Drug
Antimalarial medications or simply antimalarials are a type of antiparasitic chemical agent, often naturally derived, that can be used to treat or to prevent malaria, in the latter case, most often aiming at two susceptible target groups, young children and pregnant women. As of 2018, modern treatments, including for severe malaria, continued to depend on therapies deriving historically from quinine and artesunate, both parenteral (injectable) drugs, expanding from there into the many classes of available modern drugs. Incidence and distribution of the disease ("malaria burden") is expected to remain high, globally, for many years to come; moreover, known antimalarial drugs have repeatedly been observed to elicit resistance in the malaria parasite—including for combination therapies featuring artemisinin, a drug of last resort, where resistance has now been observed in Southeast Asia. As such, the needs for new antimalarial agents and new strategies of treatment (e.g., new com ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Morbidity
A disease is a particular abnormal condition that adversely affects the structure or function of all or part of an organism and is not immediately due to any external injury. Diseases are often known to be medical conditions that are associated with specific signs and symptoms. A disease may be caused by external factors such as pathogens or by internal dysfunctions. For example, internal dysfunctions of the immune system can produce a variety of different diseases, including various forms of immunodeficiency, hypersensitivity, allergies, and autoimmune disorders. In humans, ''disease'' is often used more broadly to refer to any condition that causes pain, dysfunction, distress, social problems, or death to the person affected, or similar problems for those in contact with the person. In this broader sense, it sometimes includes injuries, disabilities, disorders, syndromes, infections, isolated symptoms, deviant behaviors, and atypical variations of structure and f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Endemic
Endemism is the state of a species being found only in a single defined geographic location, such as an island, state, nation, country or other defined zone; organisms that are indigenous to a place are not endemic to it if they are also found elsewhere. For example, the Cape sugarbird is found exclusively in southwestern South Africa and is therefore said to be ''endemic'' to that particular part of the world. An endemic species can also be referred to as an ''endemism'' or, in scientific literature, as an ''endemite''. Similarly, many species found in the Western ghats of India are examples of endemism. Endemism is an important concept in conservation biology for measuring biodiversity in a particular place and evaluating the risk of extinction for species. Endemism is also of interest in evolutionary biology, because it provides clues about how changes in the environment cause species to undergo range shifts (potentially expanding their range into a larger area or bec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Incidence Rate
In epidemiology Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and Risk factor (epidemiology), determinants of health and disease conditions in a defined population, and application of this knowledge to prevent dise ..., incidence reflects the number of new cases of a given medical condition in a population within a specified period of time. Incidence proportion Incidence proportion (IP), also known as cumulative incidence, is defined as the probability that a particular event, such as occurrence of a particular disease, has occurred in a specified period: Incidence = \frac For example, if a population contains 1,000 persons and 28 develop a condition from the time the disease first occurred until two years later, the cumulative incidence is 28 cases per 1,000 persons, i.e. 2.8%. Incidence rate The incidence rate can be calculated by dividing the number of subjects developing a disease by the total time at risk from all patie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Panama
Panama, officially the Republic of Panama, is a country in Latin America at the southern end of Central America, bordering South America. It is bordered by Costa Rica to the west, Colombia to the southeast, the Caribbean Sea to the north, and the Pacific Ocean to the south. Its capital and largest city is Panama City, whose metropolitan area is home to nearly half of the country's over million inhabitants. Before the arrival of Spanish Empire, Spanish colonists in the 16th century, Panama was inhabited by a number of different Indigenous peoples of Panama, indigenous tribes. It Independence Act of Panama, broke away from Spain in 1821 and joined the Republic of Gran Colombia, a union of Viceroyalty of New Granada, Nueva Granada, Ecuador, and Venezuela. After Gran Colombia dissolved in 1831, Panama and Nueva Granada eventually became the Republic of Colombia. With the backing of the United States, Panama seceded from Colombia in 1903, allowing the construction of the Panama Ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nicaragua
Nicaragua, officially the Republic of Nicaragua, is the geographically largest Sovereign state, country in Central America, comprising . With a population of 7,142,529 as of 2024, it is the third-most populous country in Central America after Guatemala and Honduras. Nicaragua is bordered by Honduras to the north, the Caribbean Sea to the east, Costa Rica to the south, and the Pacific Ocean and shares maritime borders with El Salvador to the west and Colombia to the east. The country's largest city and national capital is Managua, the List of largest cities in Central America#Largest cities proper, fourth-largest city in Central America, with a population of 1,055,247 as of 2020. Nicaragua is known as "the breadbasket of Central America" due to having the most fertile soil and arable land in all of Central America. Nicaragua's multiethnic population includes people of mestizo, indigenous, European, and African heritage. The country's most spoken language is Spanish language, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Honduras
Honduras, officially the Republic of Honduras, is a country in Central America. It is bordered to the west by Guatemala, to the southwest by El Salvador, to the southeast by Nicaragua, to the south by the Pacific Ocean at the Gulf of Fonseca, and to the north by the Gulf of Honduras, a large inlet of the Caribbean Sea. Its Capital city, capital and largest city is Tegucigalpa. Honduras was home to several important Mesoamerican cultures, most notably the Maya civilization, Maya, before Spanish colonization of the Americas, Spanish colonization in the sixteenth century. The Spanish introduced Catholic Church, Catholicism and the now predominant Spanish language, along with numerous customs that have blended with the indigenous culture. Honduras became independent in 1821 and has since been a republic, although it has consistently endured much social strife and political instability, and remains one of the poorest countries in the Western Hemisphere. In 1960, the northern part o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Guatemala
Guatemala, officially the Republic of Guatemala, is a country in Central America. It is bordered to the north and west by Mexico, to the northeast by Belize, to the east by Honduras, and to the southeast by El Salvador. It is hydrologically bordered to the south by the Pacific Ocean and to the northeast by the Gulf of Honduras. The territory of modern Guatemala hosted the core of the Maya civilization, which extended across Mesoamerica; in the 16th century, most of this was Spanish conquest of Guatemala, conquered by the Spanish and claimed as part of the viceroyalty of New Spain. Guatemala attained independence from Spain and Mexico in 1821. From 1823 to 1841, it was part of the Federal Republic of Central America. For the latter half of the 19th century, Guatemala suffered instability and civil strife. From the early 20th century, it was ruled by a series of dictators backed by the United States. In 1944, authoritarian leader Jorge Ubico was overthrown by a pro-democratic m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Belize
Belize is a country on the north-eastern coast of Central America. It is bordered by Mexico to the north, the Caribbean Sea to the east, and Guatemala to the west and south. It also shares a maritime boundary with Honduras to the southeast. Part of the Caribbean region, Belize is a member of the Caribbean Community (CARICOM) and the Commonwealth Caribbean, the historical British West Indies. The Maya civilization spread into the area of Belize between 1500 BCE and 300 CE and flourished until about 1200. European contact began in 1502–04 when Christopher Columbus sailed along the Gulf of Honduras. European exploration was begun by English settlers in 1638. Spanish Empire, Spain and Kingdom of Great Britain, Britain both laid claim to the land until Britain defeated the Spanish in the Battle of St. George's Caye (1798). It became British Honduras, a British colony in 1840, and a Crown colony in 1862. Belize achieved its independence from the United Kingdom on 21 September ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
