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Allan Wilson (biologist)
Allan Charles Wilson FRS AAA&S (18 October 1934 – 21 July 1991) was a professor of biochemistry at the University of California, Berkeley, a pioneer in the use of molecular approaches to understand evolutionary change and reconstruct phylogenies, and a revolutionary contributor to the study of human evolution. He was one of the most significant figures in post-war biology; his work attracted a great deal of attention both from within and outside the academic world. He is the only New Zealander to have won the MacArthur Fellowship. He is best known for experimental demonstration of the concept of the molecular clock (with his doctoral student Vincent Sarich), which was theoretically postulated by Linus Pauling and Emile Zuckerkandl, revolutionary insights into the nature of the molecular anthropology of higher primates and human evolution, and the so-called Mitochondrial Eve hypothesis (with his doctoral students Rebecca L. Cann and Mark Stoneking). Early life and educ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ngāruawāhia
Ngāruawāhia () is a town in the Waikato region of the North Island of New Zealand. It is located north-west of Hamilton, New Zealand, Hamilton at the confluence of the Waikato River, Waikato and Waipā Rivers, adjacent to the Hakarimata Range. Ngāruawāhia is in the Hamilton Urban Area, the fourth largest Urban areas of New Zealand, urban area in New Zealand. The location was once considered as a potential capital of New Zealand. Demographics Ngāruawāhia covers and had an estimated population of as of with a population density of people per km2. Ngāruawāhia had a population of 7,992 in the 2023 New Zealand census, an increase of 1,005 people (14.4%) since the 2018 New Zealand census, 2018 census, and an increase of 2,310 people (40.7%) since the 2013 New Zealand census, 2013 census. There were 3,951 males, 4,020 females and 21 people of non-binary gender, other genders in 2,442 dwellings. 2.6% of people identified as LGBTQ, LGBTIQ+. The median age was 31.7 years (c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MacArthur Fellowship
The MacArthur Fellows Program, also known as the MacArthur Fellowship and colloquially called the "Genius Grant", is a prize awarded annually by the MacArthur Foundation, John D. and Catherine T. MacArthur Foundation to typically between 20 and 30 individuals working in any field who have shown "extraordinary originality and dedication in their creative pursuits and a marked capacity for self-direction" and are citizens or residents of the United States. According to the foundation's website, "the fellowship is not a reward for past accomplishments but rather an investment in a person's originality, insight, and potential", but it also says such potential is "based on a track record of significant accomplishments". The current prize is $800,000 paid over five years in quarterly installments. Previously, it was $625,000. This figure was increased from $500,000 in 2013 with the release of a review of the MacArthur Fellows Program. The award has been called "one of the most signifi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Primates
Primates is an order of mammals, which is further divided into the strepsirrhines, which include lemurs, galagos, and lorisids; and the haplorhines, which include tarsiers and simians ( monkeys and apes). Primates arose 74–63 million years ago first from small terrestrial mammals, which adapted for life in tropical forests: many primate characteristics represent adaptations to the challenging environment among tree tops, including large brain sizes, binocular vision, color vision, vocalizations, shoulder girdles allowing a large degree of movement in the upper limbs, and opposable thumbs (in most but not all) that enable better grasping and dexterity. Primates range in size from Madame Berthe's mouse lemur, which weighs , to the eastern gorilla, weighing over . There are 376–524 species of living primates, depending on which classification is used. New primate species continue to be discovered: over 25 species were described in the 2000s, 36 in the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecular Anthropology
Molecular anthropology, also known as genetic anthropology, is the study of how molecular biology has contributed to the understanding of human evolution. This field of anthropology examines evolutionary links between ancient and modern human populations, as well as between contemporary species. Generally, comparisons are made between sequences, either DNA or protein sequences; however, early studies used comparative serology. By examining DNA sequences in different populations, scientists can determine the closeness of relationships between populations (or within populations). Certain similarities in genetic makeup let molecular anthropologists determine whether or not different groups of people belong to the same haplogroup, and thus if they share a common geographical origin. This is significant because it allows anthropologists to trace patterns of migration and settlement, which gives helpful insight as to how contemporary populations have formed and progressed over time. Mol ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emile Zuckerkandl
Émile Zuckerkandl (July 4, 1922 – November 9, 2013) was an Austrian-born French biologist considered one of the founders of the field of molecular evolution. He introduced, with Linus Pauling, the concept of the " molecular clock", which enabled the neutral theory of molecular evolution. Life and work Zuckerkandl was raised in Vienna, Austria in a household of intellectuals, but his family relocated in 1938 to Paris, and later Algiers, to escape the racial policy of Nazi Germany with respect to Jews. At the end of World War II, he spent one year at the University of Paris ( Sorbonne), then came to the United States to study physiology—earning a master's degree in 1947 from the University of Illinois, under C. Ladd Prosser—then returned to the Sorbonne to complete a Ph.D. in biology. Zuckerkandl developed a strong interest in molecular problems; his early research at a marine biology lab in Roscoff emphasized the roles of copper oxidases and hemocyanin in the molt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Linus Pauling
Linus Carl Pauling ( ; February 28, 1901August 19, 1994) was an American chemist and peace activist. He published more than 1,200 papers and books, of which about 850 dealt with scientific topics. ''New Scientist'' called him one of the 20 greatest scientists of all time. For his scientific work, Pauling was awarded the Nobel Prize in Chemistry in 1954. For his peace activism, he was awarded the Nobel Peace Prize in 1962. He is one of five people to have Nobel Prize#Multiple laureates, won more than one Nobel Prize. Of these, he is the only person to have been awarded two unshared Nobel Prizes, and one of two people to be awarded Nobel Prizes in different fields, the other being Marie Curie. Pauling was one of the founders of the fields of quantum chemistry and molecular biology. His contributions to the theory of the chemical bond include the concept of orbital hybridisation and the first accurate scale of electronegativity, electronegativities of the elements. Pauling also wo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecular Clock
The molecular clock is a figurative term for a technique that uses the mutation rate of biomolecules to deduce the time in prehistory when two or more life forms diverged. The biomolecular data used for such calculations are usually nucleotide sequences for DNA, RNA, or amino acid sequences for proteins. Early discovery and genetic equidistance The notion of the existence of a so-called "molecular clock" was first attributed to Émile Zuckerkandl and Linus Pauling who, in 1962, noticed that the number of amino acid differences in hemoglobin between different lineages changes roughly linearly with time, as estimated from fossil evidence. They generalized this observation to assert that the rate of evolutionary change of any specified protein was approximately constant over time and over different lineages (known as the molecular clock hypothesis). The genetic equidistance phenomenon was first noted in 1963 by Emanuel Margoliash, who wrote: "It appears that the number ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biology
Biology is the scientific study of life and living organisms. It is a broad natural science that encompasses a wide range of fields and unifying principles that explain the structure, function, growth, History of life, origin, evolution, and distribution of life. Central to biology are five fundamental themes: the cell (biology), cell as the basic unit of life, genes and heredity as the basis of inheritance, evolution as the driver of biological diversity, energy transformation for sustaining life processes, and the maintenance of internal stability (homeostasis). Biology examines life across multiple biological organisation, levels of organization, from molecules and cells to organisms, populations, and ecosystems. Subdisciplines include molecular biology, physiology, ecology, evolutionary biology, developmental biology, and systematics, among others. Each of these fields applies a range of methods to investigate biological phenomena, including scientific method, observation, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Evolution
''Homo sapiens'' is a distinct species of the hominid family of primates, which also includes all the great apes. Over their evolutionary history, humans gradually developed traits such as Human skeletal changes due to bipedalism, bipedalism, dexterity, and complex language, as well as interbreeding with other hominins (a tribe of the Homininae, African hominid subfamily), indicating that human evolution was not linear but weblike. The study of the origins of humans involves Interdisciplinary, several scientific disciplines, including Biological anthropology, physical and evolutionary anthropology, paleontology, and genetics; the field is also known by the terms anthropogeny, anthropogenesis, and anthropogony—with the latter two sometimes used to refer to the related subject of hominization. Primate evolution, Primates diverged from other mammals about (Myr, mya), in the Late Cretaceous period, with their earliest fossils appearing over 55 mya, during the Paleocene. Prima ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phylogeny
A phylogenetic tree or phylogeny is a graphical representation which shows the evolutionary history between a set of species or Taxon, taxa during a specific time.Felsenstein J. (2004). ''Inferring Phylogenies'' Sinauer Associates: Sunderland, MA. In other words, it is a branching diagram or a tree (graph theory), tree showing the evolutionary relationships among various biological species or other entities based upon similarities and differences in their physical or genetic characteristics. In evolutionary biology, all life on Earth is theoretically part of a single phylogenetic tree, indicating common ancestry. Phylogenetics is the study of phylogenetic trees. The main challenge is to find a phylogenetic tree representing optimal evolutionary ancestry between a set of species or taxa. computational phylogenetics, Computational phylogenetics (also phylogeny inference) focuses on the algorithms involved in finding optimal phylogenetic tree in the phylogenetic landscape. Phylogene ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Evolution
Evolution is the change in the heritable Phenotypic trait, characteristics of biological populations over successive generations. It occurs when evolutionary processes such as natural selection and genetic drift act on genetic variation, resulting in certain characteristics becoming more or less common within a population over successive generations. The process of evolution has given rise to biodiversity at every level of biological organisation. The scientific theory of evolution by natural selection was conceived independently by two British naturalists, Charles Darwin and Alfred Russel Wallace, in the mid-19th century as an explanation for why organisms are adapted to their physical and biological environments. The theory was first set out in detail in Darwin's book ''On the Origin of Species''. Evolution by natural selection is established by observable facts about living organisms: (1) more offspring are often produced than can possibly survive; (2) phenotypic variatio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecular Biology
Molecular biology is a branch of biology that seeks to understand the molecule, molecular basis of biological activity in and between Cell (biology), cells, including biomolecule, biomolecular synthesis, modification, mechanisms, and interactions. Though cells and other microscopic structures had been observed in living organisms as early as the 18th century, a detailed understanding of the mechanisms and interactions governing their behavior did not emerge until the 20th century, when technologies used in physics and chemistry had advanced sufficiently to permit their application in the biological sciences. The term 'molecular biology' was first used in 1945 by the English physicist William Astbury, who described it as an approach focused on discerning the underpinnings of biological phenomena—i.e. uncovering the physical and chemical structures and properties of biological molecules, as well as their interactions with other molecules and how these interactions explain observ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
