|
Alfred Jost
Alfred Jost (1916–1991) was a French endocrinologist, and an early researcher in the field of fetal endocrinology. He is known for his discovery of the Müllerian inhibitor, now called anti-Müllerian hormone (AMH) or Müllerian inhibiting substance (MIS). His research demonstrated how hormones affect the development of male and female sex characteristics. Career Jost was a professor at the University of Paris, and was head of the Department of Comparative Physiology there in 1972. Jost was known for applying surgical methods to fetal endocrinology. He also taught many pre-doctoral students. Research During the 1950s and 1960s Jost studied the mechanism of somatic sex differentiation; his research showed that male characteristics must be imposed on the fetus by the testicular hormones testosterone and AMH, and that in the absence or inactivity of these hormones, the fetus becomes phenotypically female.However, this has been discredited by recent studies. Jost also stud ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Strasbourg
Strasbourg ( , ; ; ) is the Prefectures in France, prefecture and largest city of the Grand Est Regions of France, region of Geography of France, eastern France, in the historic region of Alsace. It is the prefecture of the Bas-Rhin Departments of France, department and the Seat of the European Parliament in Strasbourg, official seat of the European Parliament. The city has about three hundred thousand inhabitants, and together Eurométropole de Strasbourg, Greater Strasbourg and the arrondissement of Strasbourg have over five hundred thousand. Strasbourg's functional area (France), metropolitan area had a population of 860,744 in 2020, making it the eighth-largest metro area in France and home to 14% of the Grand Est region's inhabitants. The transnational Eurodistrict Strasbourg-Ortenau Eurodistrict, Strasbourg-Ortenau had a population of roughly 1,000,000 in 2022. Strasbourg is one of the ''de facto'' four main capitals of the European Union (alongside Brussels, Luxembourg ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
French People
French people () are a nation primarily located in Western Europe that share a common Culture of France, French culture, History of France, history, and French language, language, identified with the country of France. The French people, especially the native speakers of langues d'oïl from northern and central France, are primarily descended from Roman people, Romans (or Gallo-Romans, western European Celts, Celtic and Italic peoples), Gauls (including the Belgae), as well as Germanic peoples such as the Franks, the Visigoths, the Suebi and the Burgundians who settled in Gaul from east of the Rhine after the fall of the Roman Empire, as well as various later waves of lower-level irregular migration that have continued to the present day. The Norsemen also settled in Normandy in the 10th century and contributed significantly to the ancestry of the Normans. Furthermore, regional ethnic minorities also exist within France that have distinct lineages, languages and cultures such ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Endocrinology
Endocrinology (from ''endocrine system, endocrine'' + ''wikt:-logy#Suffix, -ology'') is a branch of biology and medicine dealing with the endocrine system, its diseases, and its specific secretions known as hormones. It is also concerned with the integration of developmental events proliferation, growth, and differentiation, and the psychological or behavioral activities of metabolism, human development (biology), growth and development, tissue (biology), tissue function, sleep, digestion, Respiration (physiology), respiration, excretion, mood (psychology), mood, Stress (physiology), stress, lactation, Motor coordination, movement, reproduction, and sensory perception caused by hormones. Specializations include behavioral endocrinology and comparative endocrinology. The endocrine system consists of several glands, all in different parts of the body, that secrete hormones directly into the blood rather than into a Duct (anatomy), duct system. Therefore, endocrine glands are regarde ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Collège De France
The (), formerly known as the or as the ''Collège impérial'' founded in 1530 by François I, is a higher education and research establishment () in France. It is located in Paris near La Sorbonne. The has been considered to be France's most prestigious research establishment. It is an associate member of PSL University. Research and teaching are closely linked at the , whose ambition is to teach "the knowledge that is being built up in all fields of literature, science and the arts". Overview As of 2021, 21 Nobel Prize winners and 9 Fields Medalists have been affiliated with the Collège. It does not grant degrees. Each professor is required to give lectures where attendance is free and open to anyone. Professors, about 50 in number, are chosen by the professors themselves, from a variety of disciplines, in both science and the humanities. The motto of the Collège is ''Docet Omnia'', Latin for "It teaches everything"; its goal is to "teach science in the making" and ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anti-Müllerian Hormone
Anti-Müllerian hormone (AMH), also known as Müllerian-inhibiting hormone (MIH), is a glycoprotein hormone structurally related to Activin and inhibin, inhibin and activin from the transforming growth factor beta superfamily, whose key roles are in growth differentiation and folliculogenesis. In humans, it is encoded by the gene, on chromosome 19p13.3, while its Receptor (biochemistry), receptor is encoded by the gene on chromosome 12. AMH is activated by SOX9 in the Sertoli cells of the male fetus. Its expression inhibits the development of the female reproductive tract, or Müllerian ducts (paramesonephric ducts), in the male embryo, thereby arresting the development of fallopian tubes, uterus, and upper vagina. ''AMH'' expression is critical to sex differentiation at a specific time during fetal development, and appears to be tightly regulated by nuclear receptor Steroidogenic factor 1, SF-1, GATA transcription factor, transcription GATA factors, sex-reversal gene DAX1, an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sex Differentiation
Sexual differentiation is the process of development of the sex differences between males and females from an undifferentiated zygote. Sex differentiation is usually distinct from sex determination; sex determination is the designation of the development stage towards either male or female, while sex differentiation is the pathway towards the development of the phenotype. In many species, testicular or ovarian differentiation begins with the appearance of Sertoli cells in males and granulosa cells in females. As embryos develop into mature adults, sex differences develop at many levels, including chromosomes, gonads, hormones, and anatomy. Beginning with determining sex by genetic and/or environmental factors, humans and other organisms proceed towards different differentiation pathways as they grow and develop. Sex determination systems Humans, many mammals, and some insects and other animals have an XY sex-determination system. Humans have 46 chromosomes, including tw ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Seminiferous Tubule
Seminiferous tubules are located within the testicles, and are the specific location of meiosis, and the subsequent creation of male gametes, namely spermatozoa. Structure The epithelium of the tubule consists of a type of sustentacular cells known as Sertoli cells, which are tall, columnar type cells that line the tubule. In between the Sertoli cells are spermatogenic cells, which differentiate through meiosis to sperm cells. Sertoli cells function to nourish the developing sperm cells. They secrete androgen-binding protein, a binding protein which increases the concentration of testosterone. There are two types: convoluted and straight, convoluted toward the lateral side, and straight as the tubule comes medially to form ducts that will exit the testis. The seminiferous tubules are formed from the testis cords that develop from the primitive gonadal cords, formed from the gonadal ridge. Function Spermatogenesis, the process for producing spermatozoa, takes place in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
French Academy Of Sciences
The French Academy of Sciences (, ) is a learned society, founded in 1666 by Louis XIV at the suggestion of Jean-Baptiste Colbert, to encourage and protect the spirit of French Scientific method, scientific research. It was at the forefront of scientific developments in Europe in the 17th and 18th centuries, and is one of the earliest Academy of Sciences, Academies of Sciences. Currently headed by Patrick Flandrin (President of the academy), it is one of the five Academies of the . __TOC__ History The Academy of Sciences traces its origin to Colbert's plan to create a general academy. He chose a small group of scholars who met on 22 December 1666 in the King's library, near the present-day Bibliothèque nationale de France, Bibliothèque Nationale, and thereafter held twice-weekly working meetings there in the two rooms assigned to the group. The first 30 years of the academy's existence were relatively informal, since no statutes had as yet been laid down for the ins ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1916 Births
Events Below, the events of the First World War have the "WWI" prefix. January * January 1 – The British Empire, British Royal Army Medical Corps carries out the first successful blood transfusion, using blood that has been stored and cooled. * January 9 – WWI: Gallipoli Campaign – The last British troops are evacuated from Gallipoli, as the Ottoman Empire prevails over a joint British and French operation to capture Constantinople. * January 10 – WWI: Erzurum Offensive – Russia defeats the Ottoman Empire. * January 12 – The Gilbert and Ellice Islands Colony, part of the British Empire, is established in modern-day Tuvalu and Kiribati. * January 13 – WWI: Battle of Wadi (1916), Battle of Wadi – Ottoman Empire forces defeat the British, during the Mesopotamian campaign in modern-day Iraq. * January 29 – WWI: Paris is bombed by German Empire, German zeppelins. * January 31 – WWI: An attack is planned on Verdun, France. Febru ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1991 Deaths
This is a list of lists of deaths of notable people, organized by year. New deaths articles are added to their respective month (e.g., Deaths in ) and then linked below. 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 Earlier years ''Deaths in years earlier than this can usually be found in the main articles of the years.'' See also * Lists of deaths by day * Deaths by year (category) {{DEFAULTSORT:deaths by year ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
French Endocrinologists
French may refer to: * Something of, from, or related to France ** French language, which originated in France ** French people, a nation and ethnic group ** French cuisine, cooking traditions and practices Arts and media * The French (band), a British rock band * "French" (episode), a live-action episode of ''The Super Mario Bros. Super Show!'' * ''Française'' (film), a 2008 film * French Stewart (born 1964), American actor Other uses * French (surname), a surname (including a list of people with the name) * French (tunic), a type of military jacket or tunic * French's, an American brand of mustard condiment * French (catheter scale), a unit of measurement * French Defence, a chess opening * French kiss, a type of kiss See also * France (other) * Franch, a surname * French Revolution (other) * French River (other), several rivers and other places * Frenching (other) Frenching may refer to: * Frenching (automobile), recessing or moul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
