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Alex Jadad
Alejandro R. Jadad Bechara (Alex Jadad; born August 9, 1963) is a Canadian-Colombian physician-scientist, clinical epidemiologist, and public health scholar. His work focuses on evidence-based medicine, networks of trust, simulation scenarios, digital health, end-of-life care and human-machine collaboration. He is also known as the developer of the Jadad Scale, the first validated tool to assess the methodological quality of clinical trials, and the Founder of the Centre for Global eHealth Innovation (now the Centre for Digital Therapeutics) in Toronto, a simulator of the future of healthcare and medicine. In 2021, he became member of the global Public Health Leadership Coalition, a group assembled by the World Federation of Public Health Associations from members of over 130 national and international public health organizations, to propose evidence-informed options with which to tackle existential threats in the 21st century. Early life and education Born in Medellín, Co ...
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David Sackett
David Lawrence Sackett (November 17, 1934 – May 13, 2015) was an American-Canadian physician and a pioneer in evidence-based medicine. He is known as one of the fathers of Evidence-Based Medicine. He founded the first department of clinical epidemiology in Canada at McMaster University, and the Oxford Centre for Evidence-Based Medicine. He is well known for his textbooks ''Clinical Epidemiology'' and ''Evidence-Based Medicine''. One of his more famous quotes is: "Half of what you learn in medical school is dead wrong." Education Sackett obtained his medical degree at the University of Illinois College of Medicine, and a Master of Science in Epidemiology from Harvard University. Career David Sackett made seminal contributions to the science of health care and the teaching and practice of medicine. He did so through vision (about how to improve health care through research), innovation (in research methods for health care and education of researchers and clinicians), and eng ...
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Open University Of Catalonia
The Open University of Catalonia (; ) is a private Open supported learning, open university based in Barcelona, Spain. The UOC offers graduate and postgraduate programs in Catalan language, Catalan, Spanish language, Spanish and English language, English in fields such as Psychology, Computer Science, Education sciences, Information society, Information and Knowledge Society, and Economics. Also, an Information and Knowledge Society Doctoral Program is available that explores research fields such as e-law, e-learning, network society, education, and online communities. It has support centers in a number of cities in Spain, Andorra, Mexico and Colombia. History The UOC was created in 1994 as a result of the Parliament of Catalonia urging the Government of the Generalitat de Catalunya, Generalitat of Catalonia to take the relevant measures to consolidate a distance learning system. It was constituted through a public deed on October 6, 1994, adopting the legal form of a foundati ...
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Cochrane Collaboration
Cochrane is a British international charitable organisation formed to synthesize medical research findings to facilitate evidence-based choices about health interventions involving health professionals, patients and policy makers. It includes 53 review groups that are based at research institutions worldwide. Cochrane has over volunteer experts from around the world. The group conducts systematic reviews of healthcare interventions and diagnostic tests and publishes them in the Cochrane Library. While Cochrane reviews typically focus on randomized controlled trials, some reviews, particularly in areas such as public and occupational health, also incorporate other study designs. These may include non-randomised observational studies as well as controlled before–after (CBA) studies and interrupted time-series studies. According to the Library, articles are available via one-click access, though some may require registration or a subscription. History Cochrane, previo ...
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Balliol College
Balliol College () is a constituent college of the University of Oxford. Founded in 1263 by nobleman John I de Balliol, it has a claim to be the oldest college in Oxford and the English-speaking world. With a governing body of a master and around 80 fellows, the college's main buildings are located on Broad Street with additional buildings to the east in Jowett Walk and Holywell Manor. As one of the larger colleges of Oxford University, Balliol typically has around 400 of both undergraduates and graduates. The college pioneered the PPE degree in the 1920s. Balliol has notable alumni from a wide range of disciplines. These include 13 Nobel Prize winners and four British prime ministers. History and governance Foundation and origins Balliol College was founded in about 1263 by John I de Balliol under the guidance of Walter of Kirkham, the Bishop of Durham. According to legend, the founder had abducted the bishop as part of a land dispute and as a penance he was publicly b ...
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Crack Cocaine
Crack cocaine, commonly known simply as crack, and also known as rock, is a free base form of the stimulant cocaine that can be Smoking, smoked. Crack offers a short, intense Euphoria (emotion), high to smokers. The ''Manual of Adolescent Substance Abuse Treatment'' calls it the most Addictive drug, addictive form of cocaine. Crack cocaine first saw widespread use as a recreational drug in primarily Poverty in the United States, impoverished neighborhoods in New York City, Philadelphia, Baltimore, Washington, D.C., Los Angeles, San Francisco and Miami in late 1984 and 1985. This rapid increase in use and availability was named the "Crack epidemic in the United States, crack epidemic", which began to wane in the 1990s. The use of another highly addictive stimulant drug, crystal meth, became popular between 1994 and 2004. Terminology The origin of the name "crack" comes from the "crackling" sound (and hence the onomatopoeic moniker "crack") that is produced when the cocaine and ...
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Bogotá
Bogotá (, also , , ), officially Bogotá, Distrito Capital, abbreviated Bogotá, D.C., and formerly known as Santa Fe de Bogotá (; ) during the Spanish Imperial period and between 1991 and 2000, is the capital city, capital and largest city of Colombia, and one of the List of largest cities, largest cities in the world. The city is administered as the Capital District, as well as the capital of, though not politically part of, the surrounding department of Cundinamarca Department, Cundinamarca. Bogotá is a territorial entity of the first order, with the same administrative status as the departments of Colombia. It is the main political, economic, administrative, industrial, cultural, aeronautical, technological, scientific, medical and educational center of the country and northern South America. Bogotá was founded as the capital of the New Kingdom of Granada on 6 August 1538 by Spanish conquistador Gonzalo Jiménez de Quesada after a harsh Spanish conquest of the Muisca, e ...
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Medellín
Medellín ( ; or ), officially the Special District of Science, Technology and Innovation of Medellín (), is the List of cities in Colombia, second-largest city in Colombia after Bogotá, and the capital of the department of Antioquia Department, Antioquia. It is located in the Aburrá Valley, a central region of the Andes Mountains, in northwestern South America. The city's population was 2,427,129 at the 2018 Colombian census, 2018 census. The Metropolitan Area of Medellín, metro area of Medellín is the second-largest urban agglomeration in Colombia in terms of population and economy, with more than 4 million people. In 1616, the Spaniard Francisco de Herrera Campuzano erected a small indigenous village (''poblado'') known as "Lawrence of Rome, Saint Lawrence of Aburrá" (''San Lorenzo de Aburrá''), located in the present-day El Poblado (Medellín), El Poblado commune. On 2 November 1675, the queen consort Mariana of Austria founded the "Town of Virgin of Candelaria, Our L ...
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Toronto
Toronto ( , locally pronounced or ) is the List of the largest municipalities in Canada by population, most populous city in Canada. It is the capital city of the Provinces and territories of Canada, Canadian province of Ontario. With a population of 2,794,356 in 2021, it is the List of North American cities by population, fourth-most populous city in North America. The city is the anchor of the Golden Horseshoe, an urban agglomeration of 9,765,188 people (as of 2021) surrounding the western end of Lake Ontario, while the Greater Toronto Area proper had a 2021 population of 6,712,341. As of 2024, the census metropolitan area had an estimated population of 7,106,379. Toronto is an international centre of business, finance, arts, sports, and culture, and is recognized as one of the most multiculturalism, multicultural and cosmopolitanism, cosmopolitan cities in the world. Indigenous peoples in Canada, Indigenous peoples have travelled through and inhabited the Toronto area, ...
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Clinical Trial
Clinical trials are prospective biomedical or behavioral research studies on human subject research, human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, pharmaceutical drug, drugs, medical nutrition therapy, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison. Clinical trials generate data on dosage, safety and efficacy. They are conducted only after they have received institutional review board, health authority/ethics committee approval in the country where approval of the therapy is sought. These authorities are responsible for vetting the risk/benefit ratio of the trial—their approval does not mean the therapy is 'safe' or effective, only that the trial may be conducted. Depending on product type and development stage, investigators initially enroll volunteers or patients into small Pilot experiment, pi ...
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Methodology
In its most common sense, methodology is the study of research methods. However, the term can also refer to the methods themselves or to the philosophical discussion of associated background assumptions. A method is a structured procedure for bringing about a certain goal, like acquiring knowledge or verifying knowledge claims. This normally involves various steps, like choosing a Sample (statistics), sample, Data collection, collecting data from this sample, and interpreting the data. The study of methods concerns a detailed description and analysis of these processes. It includes evaluative aspects by comparing different methods. This way, it is assessed what advantages and disadvantages they have and for what research goals they may be used. These descriptions and evaluations depend on philosophical background assumptions. Examples are how to conceptualize the studied phenomena and what constitutes evidence for or against them. When understood in the widest sense, methodology al ...
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