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Albert Schatz (scientist)
Albert Israel Schatz (2 February 1920 – 17 January 2005) was an American microbiologist and academic who discovered streptomycin, the first antibiotic known to be effective for the treatment of tuberculosis. He graduated from Rutgers University in 1942 with a bachelor's degree in soil microbiology, and received his doctorate from Rutgers in 1945. His PhD research led directly to the discovery of streptomycin. Born to a family of farmers, Schatz was inspired to study soil science for its potential applicability to take up his family occupation. Topping his class at Rutgers in 1942, he immediately worked under Selman Waksman, then head of the Department of Soil Microbiology, but was drafted to the US Army to serve in the World War II. After a back injury led to his discharge from the army, he rejoined Waksman in 1943 as a PhD student. Working in isolation from others due to his use of the dreaded tuberculosis bacterium (''Mycobacterium tuberculosis''), he discovered a new antibio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Norwich, Connecticut
Norwich ( ) is a city in New London County, Connecticut, United States. The Yantic River, Yantic, Shetucket River, Shetucket, and Quinebaug Rivers flow into the city and form its harbor, from which the Thames River (Connecticut), Thames River flows south to Long Island Sound. The city is part of the Southeastern Connecticut Planning Region, Connecticut, Southeastern Connecticut Planning Region. The population was 40,125 at the 2020 United States Census. History The town of Norwich was founded in 1659, on the site of what is now the neighborhood of Norwichtown, by settlers from Saybrook Colony led by Major John Mason (c. 1600–1672), John Mason, James Fitch (minister), James Fitch, and Lieutenant Francis Griswold. They purchased the land "nine miles square" that became Norwich from Mohegan Sachem Uncas. One of the co-founders of Norwich was Thomas Leffingwell, who rescued Uncas when surrounded by his Narragansett people, Narragansett tribesmen, and whose son established the Leff ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mycobacterium Tuberculosis
''Mycobacterium tuberculosis'' (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. First discovered in 1882 by Robert Koch, ''M. tuberculosis'' has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid. This coating makes the cells impervious to Gram staining, and as a result, ''M. tuberculosis'' can appear weakly Gram-positive. Acid-fastness, Acid-fast stains such as Ziehl–Neelsen stain, Ziehl–Neelsen, or Fluorescence, fluorescent stains such as Auramine O, auramine are used instead to identify ''M. tuberculosis'' with a microscope. The physiology of ''M. tuberculosis'' is highly aerobic organism, aerobic and requires high levels of oxygen. Primarily a pathogen of the mammalian respiratory system, it infects the lungs. The most frequently used diagnostic methods for tuberculosis are the Mantoux test, tuberculin skin test, Acid-Fast Stain, aci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Independent
''The Independent'' is a British online newspaper. It was established in 1986 as a national morning printed paper. Nicknamed the ''Indy'', it began as a broadsheet and changed to tabloid format in 2003. The last printed edition was published on Saturday 26 March 2016, leaving only the online edition. The daily edition was named National Newspaper of the Year at the 2004 British Press Awards. ''The Independent'' won the Brand of the Year Award in The Drum Awards for Online Media 2023. History 1980s Launched in 1986, the first issue of ''The Independent'' was published on 7 October in broadsheet format.Dennis Griffiths (ed.) ''The Encyclopedia of the British Press, 1422–1992'', London & Basingstoke: Macmillan, 1992, p. 330. It was produced by Newspaper Publishing plc and created by Andreas Whittam Smith, Stephen Glover and Matthew Symonds. All three partners were former journalists at ''The Daily Telegraph'' who had left the paper towards the end of Lord Hartwell' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tooth Decay
Tooth decay, also known as caries,The word 'caries' is a mass noun, and is not a plural of 'carie'.'' is the breakdown of teeth due to acids produced by bacteria. The resulting cavities may be a number of different colors, from yellow to black. Symptoms may include pain and difficulty eating. Complications may include periodontal disease, inflammation of the tissue around the tooth, tooth loss and infection or dental abscess, abscess formation. Tooth regeneration is an ongoing Stem-cell therapy, stem cell–based field of study that aims to find methods to reverse the effects of decay; current methods are based on easing symptoms. The cause of cavities is acid from bacteria dissolving the hard tissues of the teeth (Tooth enamel, enamel, dentin and cementum). The acid is produced by the bacteria when they break down food debris or sugar on the tooth surface. Simple sugars in food are these bacteria's primary energy source and thus a diet high in simple sugar is a risk factor. I ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Pennsylvania
The University of Pennsylvania (Penn or UPenn) is a Private university, private Ivy League research university in Philadelphia, Pennsylvania, United States. One of nine colonial colleges, it was chartered in 1755 through the efforts of founder and first president Benjamin Franklin, who had advocated for an educational institution that trained leaders in academia, commerce, and public service. The university has four undergraduate schools and 12 graduate and professional schools. Schools enrolling undergraduates include the College of Arts and Sciences, the University of Pennsylvania School of Engineering and Applied Science, School of Engineering and Applied Science, the Wharton School, and the University of Pennsylvania School of Nursing, School of Nursing. Among its graduate schools are its University of Pennsylvania Law School, law school, whose first professor, James Wilson (Founding Father), James Wilson, helped write the Constitution of the United States, U.S. Cons ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Philadelphia General Hospital
The Blockley Almshouse, later known as Philadelphia General Hospital, was a charity hospital and poorhouse located in West Philadelphia. It originally opened in 1732/33 in a different part of the city as the Philadelphia Almshouse (not to be confused with the Friends' Almshouse, established 1713). Philadelphia General Hospital closed in 1977. History Origins The Blockley Almshouse had its roots in the Philadelphia Almshouse, a facility first located in the block between Third, fifth, Spruce and Pine Streets. Constructed in 1731–32, this institution provided the first government-sponsored care of the poor in America, as it offered an infirmary and hospital for the sick and insane, besides housing and feeding the impoverished. In 1767, it moved to larger quarters occupying the block between Tenth, Eleventh, Spruce and Pine Streets. This site was officially called the Philadelphia Bettering House. Old Blockley In 1835, the overcrowded Philadelphia Almshouse moved to Bl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States Air Force
The United States Air Force (USAF) is the Air force, air service branch of the United States Department of Defense. It is one of the six United States Armed Forces and one of the eight uniformed services of the United States. Tracing its origins to 1 August 1907, as a part of the United States Army Signal Corps, the USAF was established by transfer of personnel from the Army Air Forces with the enactment of the National Security Act of 1947. It is the second youngest branch of the United States Armed Forces and the fourth in United States order of precedence, order of precedence. The United States Air Force articulates its core missions as air supremacy, intelligence, surveillance, target acquisition, and reconnaissance, global integrated intelligence, surveillance and reconnaissance, airlift, rapid global mobility, Strategic bombing, global strike, and command and control. The United States Department of the Air Force, Department of the Air Force, which serves as the USAF's ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
US Army
The United States Army (USA) is the primary land service branch of the United States Department of Defense. It is designated as the Army of the United States in the United States Constitution.Article II, section 2, clause 1 of the United States Constitution (1789).See alsTitle 10, Subtitle B, Chapter 301, Section 3001 It operates under the authority, direction, and control of the United States secretary of defense. It is one of the six armed forces and one of the eight uniformed services of the United States. The Army is the most senior branch in order of precedence amongst the armed services. It has its roots in the Continental Army, formed on 14 June 1775 to fight against the British for independence during the American Revolutionary War (1775–1783). After the Revolutionary War, the Congress of the Confederation created the United States Army on 3 June 1784 to replace the disbanded Continental Army.Library of CongressJournals of the Continental Congress, Volume 27/ref> Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Streptothricin
Streptothricins are a group of antibiotics in the aminoglycoside class. The first antibiotic in the group was isolated from '' Streptomyces lavendulae'' in 1942. It was later determined to be a mixture of closely-related compounds, and is now known as nourseothricin. Although initial interest was positive because it appeared to be the first broad-spectrum antibiotic, meaning it was effective against both Gram-positive and Gram-negative Gram-negative bacteria are bacteria that, unlike gram-positive bacteria, do not retain the crystal violet stain used in the Gram staining method of bacterial differentiation. Their defining characteristic is that their cell envelope consists ... bacteria, it never found clinical use due to toxicity. However, because of the increasing need for new antibiotics due to resistance to existing antibiotics, there is a current interest in developing new drugs based on the chemical scaffold of the streptothricins. References {{reflist Aminoglyc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clavacin
Patulin is an organic compound classified as a polyketide. It is named after the fungus from which it was isolated, '' Penicillium patulum''. It is a white powder soluble in acidic water and in organic solvents. It is a lactone that is heat-stable, so it is not destroyed by pasteurization or thermal denaturation.Patulin sigmaaldrich.com However, stability following is lessened. It is a produced by a variety of molds, in particular, '' |
Actinomycin
Dactinomycin, also known as actinomycin D, is a chemotherapy medication used to treat a number of types of cancer. This includes Wilms tumor, rhabdomyosarcoma, Ewing's sarcoma, trophoblastic neoplasm, testicular cancer, and certain types of ovarian cancer. It is given by injection into a vein. Most people develop side effects. Common side effects include bone marrow suppression, vomiting, mouth ulcers, hair loss, liver problems, infections, and muscle pains. Other serious side effects include future cancers, allergic reactions, and tissue death if extravasation occurs. Use in pregnancy may harm the baby. Dactinomycin is in the cytotoxic antibiotic family of medications. It is believed to work by blocking the creation of RNA. Dactinomycin was approved for medical use in the United States in 1964. It is on the 2023 World Health Organization's List of Essential Medicines. Medical use Actinomycin is a clear, yellowish liquid administered intravenously and most comm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Guardian
''The Guardian'' is a British daily newspaper. It was founded in Manchester in 1821 as ''The Manchester Guardian'' and changed its name in 1959, followed by a move to London. Along with its sister paper, ''The Guardian Weekly'', ''The Guardian'' is part of the Guardian Media Group, owned by the Scott Trust Limited. The trust was created in 1936 to "secure the financial and editorial independence of ''The Guardian'' in perpetuity and to safeguard the journalistic freedom and liberal values of ''The Guardian'' free from commercial or political interference". The trust was converted into a limited company in 2008, with a constitution written so as to maintain for ''The Guardian'' the same protections as were built into the structure of the Scott Trust by its creators. Profits are reinvested in its journalism rather than distributed to owners or shareholders. It is considered a newspaper of record in the UK. The editor-in-chief Katharine Viner succeeded Alan Rusbridger in 2015. S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
