|
Albert J. Fornace Jr.
Albert J. Fornace Jr. (born 1949) is a professor in the departments of Oncology, Biochemistry and Molecular & Cellular Biology, and Radiation Medicine at Georgetown University. He has also been awarded the Molecular Cancer Research Chair at Lombardi Comprehensive Cancer Center, joining Georgetown in 2006 from the Harvard School of Public Health. Earlier, he was chief of the Gene Response Section at the National Cancer Institute. He graduated from La Salle College High School in Philadelphia, Pennsylvania (1967), and received his B.S. (1970) and M.D. (1972) from the Jefferson-Penn State joint pre-medical/medical program. Research career Fornace has made a variety of notable discoveries in the fields of cancer research, molecular biology, radiation biology, and toxicology with particular emphasis on understanding stress-signaling mechanisms in both normal and cancer cells. This has focused on understanding how cells and organisms respond to genotoxic (DNA damaging) agents, such as r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Georgetown University
Georgetown University is a private university, private research university in the Georgetown (Washington, D.C.), Georgetown neighborhood of Washington, D.C. Founded by Bishop John Carroll (archbishop of Baltimore), John Carroll in 1789 as Georgetown College (Georgetown University), Georgetown College, the university has grown to comprise eleven Undergraduate education, undergraduate and Postgraduate education, graduate schools, including the School of Foreign Service, Walsh School of Foreign Service, McDonough School of Business, Georgetown University School of Medicine, Medical School, Georgetown University Law Center, Law School, and a Georgetown University in Qatar, campus in Qatar. The school's main campus, on a hill above the Potomac River, is identifiable by its flagship Healy Hall, a National Historic Landmark. The school was founded by and is affiliated with the Society of Jesus, and is the oldest Catholic institution of higher education in the United States, though the m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
GADD
Gadd is a surname. Notable people with the surname include: * Anthony Gadd (1917–1996), British bobsledder * C. J. Gadd (1893–1969), British Assyriologist and curator * Christianne Gadd, former name of actress Christianne Oliveira (born 1971) * Geoffrey Michael Gadd (born 1954), British-Irish microbiologist and mycologist * Hemming Gadd (1837–1915), Swedish Army general * Hugo Gadd (1885–1968), Swedish Army major general * Knut Gadd (1916–1995), Swedish water polo player * Paul Francis Gadd (born 1944), the real name of British pop singer and convicted paedophile Gary Glitter * Renee Gadd (1908–2003), Argentine-born British film actress * Stephen Gadd (born 1964), English operatic baritone * Steve Gadd (born 1945), American drummer * Steve Gadd (born 1951), English vocalist ( Stray (band)) * Trevor Gadd (born 1952), English athlete * Will Gadd Will Gadd (born March 8, 1967) is a prominent Canadian ice climber and paraglider pilot. He formerly held the paragliding ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pennsylvania State University Alumni
Pennsylvania (; (Pennsylvania Dutch: )), officially the Commonwealth of Pennsylvania, is a state spanning the Mid-Atlantic, Northeastern, Appalachian, and Great Lakes regions of the United States. It borders Delaware to its southeast, Maryland to its south, West Virginia to its southwest, Ohio to its west, Lake Erie and the Canadian province of Ontario to its northwest, New York to its north, and the Delaware River and New Jersey to its east. Pennsylvania is the fifth-most populous state in the nation with over 13 million residents as of 2020. It is the 33rd-largest state by area and ranks ninth among all states in population density. The southeastern Delaware Valley metropolitan area comprises and surrounds Philadelphia, the state's largest and nation's sixth most populous city. Another 2.37 million reside in Greater Pittsburgh in the southwest, centered around Pittsburgh, the state's second-largest and Western Pennsylvania's largest city. The state's subseque ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard T
Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher learning in the United States and one of the most prestigious and highly ranked universities in the world. The university is composed of ten academic faculties plus Harvard Radcliffe Institute. The Faculty of Arts and Sciences offers study in a wide range of undergraduate and graduate academic disciplines, and other faculties offer only graduate degrees, including professional degrees. Harvard has three main campuses: the Cambridge campus centered on Harvard Yard; an adjoining campus immediately across Charles River in the Allston neighborhood of Boston; and the medical campus in Boston's Longwood Medical Area. Harvard's endowment is valued at $50.9 billion, making it the wealthiest academic institution in the world. Endowment in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Georgetown University Medical Center Faculty
Georgetown or George Town may refer to: Places Africa *George, South Africa, formerly known as Georgetown * Janjanbureh, Gambia, formerly known as Georgetown *Georgetown, Ascension Island, main settlement of the British territory of Ascension Island Asia *Georgetown, Allahabad, India *George Town, Chennai, India *George Town, Penang, capital city of the Malaysian state of Penang Europe * Georgetown, Blaenau Gwent, now part of the town of Tredegar in Wales * Georgetown, Dumfries and Galloway, a location in Dumfries and Galloway, Scotland *Es Castell in Minorca, Spain, originally called Georgetown North and Central America Canada *Georgetown, Alberta * Georgetown, Newfoundland and Labrador *Georgetown, Ontario *Georgetown, Prince Edward Island Caribbean *George Town, Bahamas, a village in Exuma District, Bahamas * George Town, Belize, a village in Stann Creek District, Belize *George Town, Cayman Islands, the capital city on Grand Cayman * Georgetown, Saint Vincent and the Grena ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Molecular Biologists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Radiation Research Society
The American Radiation Research Society (RRS) is an international professional association for scientists working to investigate the radiation effects from chemistry, physics, and biology perspectives and disseminates knowledge and information related to radiation research. The society was founded in 1952 with Raymond E. Zirkle as its inaugural president. The society publishes the journal Radiation Research since 1954. Presidents of the Radiation Research Society A list of the presidents of the society from its foundation to the present. * 1952 - Raymond E. Zirkle * 1953 - Gioacchino Failla * 1954 - Alexander Hollaender * 1955 - Austin M. Brues * 1956 - Henry S. Kaplan * 1957 - Howard J. Curtis * 1958 - Milton Burton * 1959 - Ernest C. Pollard * 1960 - Harvey M. Patt * 1961 - Hymer L. Friedell * 1962 - Cornelius A. Tobias * 1963 - Augustine O. Allen * 1964 - Edward Lawrence Powers Jr. * 1965 - Arthur C. Upton * 1966 - Robley D. Evans * 1967 - John L. Magee * 1968 - Arnold Hi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Institute Of Health
The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late 1880s and is now part of the United States Department of Health and Human Services. The majority of NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its own scientific research through the NIH Intramural Research Program (IRP) and provides major biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research institu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jerry Crabtree
Jerry may refer to: Animals * Jerry (Grand National winner), racehorse, winner of the 1840 Grand National * Jerry (St Leger winner), racehorse, winner of 1824 St Leger Stakes Arts, entertainment, and media * ''Jerry'' (film), a 2006 Indian film * "Jerry", a song from the album ''Young and Free'' by Rock Goddess * Tom and Jerry (other) People * Jerry (given name), including a list of people and fictional characters with the name * Harold A. Jerry, Jr. (1920–2001), New York politician * Thomas Jeremiah (d. 1775), commonly known simply as "Jerry", a free Negro in colonial South Carolina Places * Branche à Jerry, a tributary of the Baker River in Quebec and New Brunswick, Canada * Jerry, Washington, a community in the United States Other uses * Jerry (company) * Jerry (WWII), Allied nickname for Germans, originally from WWI but widely used in World War II * Jerry Rescue (1851), involving American slave William Henry, who called himself "Jerry" See also * Geri (disam ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nucleotide Excision Repair
Nucleotide excision repair is a DNA repair mechanism. DNA damage occurs constantly because of chemicals (e.g. intercalating agents), radiation and other mutagens. Three excision repair pathways exist to repair single stranded DNA damage: Nucleotide excision repair (NER), base excision repair (BER), and DNA mismatch repair (MMR). While the BER pathway can recognize specific non-bulky lesions in DNA, it can correct only damaged bases that are removed by specific glycosylases. Similarly, the MMR pathway only targets mismatched Watson-Crick base pairs. Nucleotide excision repair (NER) is a particularly important excision mechanism that removes DNA damage induced by ultraviolet light (UV). UV DNA damage results in bulky DNA adducts - these adducts are mostly thymine dimers and 6,4-photoproducts. Recognition of the damage leads to removal of a short single-stranded DNA segment that contains the lesion. The undamaged single-stranded DNA remains and DNA polymerase uses it as a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetic Recombination
Genetic recombination (also known as genetic reshuffling) is the exchange of genetic material between different organisms which leads to production of offspring with combinations of traits that differ from those found in either parent. In eukaryotes, genetic recombination during meiosis can lead to a novel set of genetic information that can be further passed on from parents to offspring. Most recombination occurs naturally and can be classified into two types: (1) ''interchromosomal'' recombination, occurring through independent assortment of alleles whose loci are on different but homologous chromosomes (random orientation of pairs of homologous chromosomes in meiosis I); & (2) ''intrachromosomal'' recombination, occurring through crossing over. During meiosis in eukaryotes, genetic recombination involves the pairing of homologous chromosomes. This may be followed by information transfer between the chromosomes. The information transfer may occur without physical exchange ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
DNA Repair
DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human cells, both normal metabolic activities and environmental factors such as radiation can cause DNA damage, resulting in tens of thousands of individual molecular lesions per cell per day. Many of these lesions cause structural damage to the DNA molecule and can alter or eliminate the cell's ability to transcribe the gene that the affected DNA encodes. Other lesions induce potentially harmful mutations in the cell's genome, which affect the survival of its daughter cells after it undergoes mitosis. As a consequence, the DNA repair process is constantly active as it responds to damage in the DNA structure. When normal repair processes fail, and when cellular apoptosis does not occur, irreparable DNA damage may occur, including double-strand breaks and DNA crosslinkages (interstrand crosslinks or ICLs). This can eventually lead to malig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
