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AbioCor
AbioCor was a total artificial heart (TAH) developed by the Massachusetts-based company AbioMed. It was fully implantable within a patient, due to a combination of advances in miniaturization, biosensors, plastics and energy transfer. The AbioCor ran on a rechargeable source of power. The internal battery was charged by a transcutaneous energy transmission (TET) system, meaning that no wires or tubes penetrated the skin, reducing the risk of infection. However, because of its size, this heart was only compatible with men who had a large frame. It had a product life expectancy of 18 months. AbioCor was surgically introduced into 15 total patients, 14 of them during a clinical trial and one after FDA approval. However, due to insufficient evidence of its efficacy, AbioMed abandoned further development of the product. History AbioMed was founded by Param Singh and David Lederman. The company began development of the AbioCor device in the 1990s, beginning animal studies in 1998 in ...
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Artificial Heart
An artificial heart is a artificial organ, device that replaces the human heart, heart. Artificial hearts are typically used as a bridge to heart transplantation, but ongoing research aims to develop a device that could permanently replace the heart when a transplant—whether from a deceased human or, experimentally, from a genetically engineered pig—is unavailable or not viable. , there are two commercially available full artificial heart devices; both are intended for temporary use (less than a year) for patients with total heart failure who are awaiting a human heart transplant. Although other similar inventions preceded it from the late 1940s, the first artificial heart to be successfully implanted in a human was the Jarvik-7 in 1982, designed by a team including Willem Johan Kolff, William DeVries and Robert Jarvik. An artificial heart is distinct from a ventricular assist device (VAD; for either one or both of the ventricles, the heart's lower chambers), which may als ...
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AbioMed
Abiomed, Inc. is a medical device technology company that operates as a stand-alone business within Johnson & Johnson's MedTech Segment. Abiomed develops and manufactures temporary external and implantable mechanical circulatory support devices. The company is headquartered in Danvers, Massachusetts with additional offices in Woburn, Baltimore, Berlin, Aachen, and Tokyo. Andrew Greenfield is President of the company, with Dr. Thorsten Siess as Executive Vice President and Chief Technology Officer and Dr. Chuck Simonton as Executive Vice President and Chief Medical Officer. According to Bloomberg, the company "engages in the research, development, and sale of medical devices to assist or replace the pumping function of the failing heart. It also provides continuum of care to heart failure patients". As of 2022, the company had secured five FDA approvals and 1,408 patents with 1,416 pending. For fiscal year 2022, Abiomed reported $1.032 billion in revenue and reported diluted earn ...
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David Lederman
David M. Lederman was an American aerospace engineer, entrepreneur, author, and humanitarian. He is noted for founding Abiomed, the company that developed AbioCor, the first fully implantable artificial heart. Biography Lederman was born in Bogota, Colombia to Israel Joseph Lederman and Rifka Lederman on May 26, 1944. His parents were immigrants who escaped the Nazis in Poland. He went to Colegio Americano and Universidad de Los Andes before his family moved to the United States in 1964. He completed his bachelor’s degree in engineering at Cornell University, where he also obtained his Master’s degree in Aerospace Engineering and Doctoral degree in Laser Physics and Aerospace Engineering. Career After graduation, Lederman went back to Colombia to work as an associate professor and director of the Universidad de Los Andes’ biomedical research department. In 1974, he relocated to the U.S. and worked for Avco Everett Research Laboratory. In this company, he was a senior re ...
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Gus Rosenberg
Gerson "Gus" Rosenberg is an American biomedical engineer. He is the Jane A. Fetter Professor of Surgery, professor of bioengineering, and chief of the Division of Applied Biomedical Engineering (previously known as the Division of Artificial Organs) at Penn State's Milton S. Hershey Medical Center and Penn State College of Medicine. Background and education Rosenberg was born on August 20, 1944, and raised in Chalfont, Pennsylvania. He studied mechanical engineering at Penn State University and received his Bachelor of Science, Master of Science, and Ph.D. degrees at the university. He began research on heart-assist pumps in 1970 as a graduate student at Penn State. His research led to a number of heart devices developed by the team that he now leads at Penn State. He was part of the team that designed the university's first heart-assist pump. Circulatory support devices Rosenberg's research and teaching have resulted in devices such as a Left Ventricular Assist device (LVAD ...
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Robert Tools
Robert L. Tools (July 31, 1942 – November 30, 2001) was the world's first recipient of a fully self-contained artificial heart, called AbioCor. The operation took place on July 2, 2001. He survived for 151 days without a living heart. Dr. Joseph Fredi at Saint Thomas Hospital suggested the experimental procedure based on his knowledge of a research project by Abiomed. While recovering from surgery, Robert had the chance to enjoy some of his favorite past time hobbies, fishing and dining out. While at Jewish Hospital, Robert became renowned and received press throughout the world on shows like Cooking Network, Dateline, ''The Tonight Show with Jay Leno'', and CNN. As a result of Robert's press, he received visits from Lt. Governors, The Oak Ridge Boys, and Muhammad Ali Muhammad Ali (; born Cassius Marcellus Clay Jr.; January 17, 1942 – June 3, 2016) was an American professional boxer and social activist. A global cultural icon, widely known by the nickname "The ...
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Penn State
#Redirect Pennsylvania State University The Pennsylvania State University (Penn State or PSU) is a Public university, public Commonwealth System of Higher Education, state-related Land-grant university, land-grant research university with campuses and facilities throughout Pennsyl ... Penn State {{Redirect category shell, {{R from abbr ...
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Implants (medicine)
Implant can refer to: Medicine *Implant (medicine), or specifically: ** Brain implant **Breast implant ** Buttock implant **Cochlear implant ** Contraceptive implant **Dental implant ** Fetal tissue implant ** Implantable cardioverter-defibrillator ** Orthopedic implant ** Prosthetic implant ** Retinal implant ** Subdermal implant ** Transdermal implant Alternative * Alien implants * Extraocular implant * Implant (body modification) * Implant (thought insertion) *Microchip implant (animal) (human) *'' The Implant'', a television episode of ''Seinfeld ''Seinfeld'' ( ) is an American television sitcom created by Larry David and Jerry Seinfeld that originally aired on NBC from July 5, 1989, to May 14, 1998, with a total of nine seasons consisting of List of Seinfeld episodes, 180 episodes. It ...'' See also * History of dental treatments * Implantation (other) * Osseointegration * Osseoincorporation {{disambig ...
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Cardiology
Cardiology () is the study of the heart. Cardiology is a branch of medicine that deals with disorders of the heart and the cardiovascular system. The field includes medical diagnosis and treatment of congenital heart defects, coronary artery disease, heart failure, valvular heart disease, and electrophysiology. Physicians who specialize in this field of medicine are called cardiologists, a sub-specialty of internal medicine. Pediatric cardiologists are pediatricians who specialize in cardiology. Physicians who specialize in cardiac surgery are called cardiothoracic surgeons or cardiac surgeons, a specialty of general surgery. Specializations All cardiologists in the branch of medicine study the disorders of the heart, but the study of adult and child heart disorders each require different training pathways. Therefore, an adult cardiologist (often simply called "cardiologist") is inadequately trained to take care of children, and pediatric cardiologists are not trained to treat ...
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Superhuman
The term superhuman refers to humans, humanoids or other beings with abilities and other qualities that exceed those naturally found in humans. These qualities may be acquired through natural ability, self-actualization or technological aids. The related concept of a super race refers to an entire category of beings with the same or varying superhuman characteristics, created from present-day human beings by deploying various means such as eugenics, euthenics, genetic engineering, nanotechnology, and/or brain–computer interfacing to accelerate the process of human evolution. Throughout history, the discussion of superhuman traits and the idea of the ideal human in physical, mental, or spiritual form has influenced politics, policy, philosophy, science and various social movements, as well as featuring prominently in culture. Groups advocating the deliberate pursuit of superhuman qualities for philosophical, political, or moral reasons are sometimes referred to as superhu ...
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Jason Statham
Jason Statham ( ; born 26 July 1967) is an English actor. He is known for portraying tough, gritty, or violent characters in various action thriller films, and has been credited for leading the resurgence of action films during the 2000s and 2010s. By 2017, his films had grossed over £1.1 billion ( $1.5 billion), making him one of the industry's most bankable stars. Films in which he has appeared in have grossed over $8.4 billion worldwide. Statham began practising Chinese martial arts, kickboxing, and karate recreationally in his youth while working at local market stalls. An avid footballer and diver, he was a member of Britain's national diving team and competed for England in the 1990 Commonwealth Games. Shortly after, he was asked to model for French Connection, Tommy Hilfiger, and Levi's in various advertising campaigns. Statham's history of working at market stalls inspired his casting in the Guy Ritchie crime films '' Lock, Stock and Two Smoking Barrels'' (1998 ...
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Chev Chelios
''Crank'' is a 2006 American action film directed by Mark Neveldine and Brian Taylor (in their directorial debut). It stars Jason Statham, Amy Smart, Jose Pablo Cantillo, Efren Ramirez and Dwight Yoakam. The title of the film comes from a slang word for methamphetamine. In the film, Chev Chelios (Statham), an LA–based British assassin, is poisoned by a synthetic drug and must keep his adrenaline flowing constantly to keep himself alive, while trying to track down the culprits responsible for poisoning him. It was followed by a sequel titled '' Crank: High Voltage''. Plot L.A.–based Englishman Chev Chelios works as a hitman under Don "Carlito" Carlos's crime empire. Chelios is contracted by Carlito to kill Don Kim, a mafia boss, as members of the Triads have been encroaching on Carlito's business. Chelios goes to Don Kim and apparently kills him. In the confusion, Ricky Verona, an ambitious small-time criminal, uses the opportunity to conspire with Carlito against Chelios: ...
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High Voltage
High voltage electricity refers to electrical potential large enough to cause injury or damage. In certain industries, ''high voltage'' refers to voltage above a certain threshold. Equipment and conductors that carry high voltage warrant special safety requirements and procedures. High voltage is used in electrical power distribution, in cathode-ray tubes, to generate X-rays and particle beams, to produce electrical arcs, for ignition, in photomultiplier tubes, and in high-power amplifier vacuum tubes, as well as other industrial, military and scientific applications. Definition The numerical definition of depends on context. Two factors considered in classifying a voltage as high voltage are the possibility of causing a spark in air, and the danger of electric shock by contact or proximity. The International Electrotechnical Commission and its national counterparts (IET, IEEE, VDE, etc.) define ''high voltage'' as above 1000  V for alternating current, and at l ...
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