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Abingdon Health
Abingdon Health is a leading international developer, manufacturer and distributor of lateral flow assay diagnostic tests, sometimes called rapid tests, lateral flow immunoassays (LFIA), lateral flow tests (LFT) or quick tests. Since its formation in 2008, Abingdon Health has developed and manufactured lateral flow rapid tests across multiple industries. Headquartered in York, with sites in Doncaster and Madison, USA. History 2008: Founded by Dr Chris Hand and Chris Yates. 2012: Acquisition of major stake in Forsite Diagnostics Ltd (Forsite); a spin-out from the UK government's Food and Environment Research Agency (now known as Animal and Plant Health Agency). 2015: Dr Chris Hand and Chris Yates are appointed chairman and Chief Executive respectively. 2017: Abingdon takes full ownership of Forsite Diagnostics, and relocates the Group's headquarters to Forsite's York facility. 2019: Growth capital investment by the Northern Powerhouse Investment Fund managed by Mercia Ass ...
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York
York is a cathedral city in North Yorkshire, England, with Roman Britain, Roman origins, sited at the confluence of the rivers River Ouse, Yorkshire, Ouse and River Foss, Foss. It has many historic buildings and other structures, such as a York Minster, minster, York Castle, castle and York city walls, city walls, all of which are Listed building, Grade I listed. It is the largest settlement and the administrative centre of the wider City of York district. It is located north-east of Leeds, south of Newcastle upon Tyne and north of London. York's built-up area had a recorded population of 141,685 at the 2021 United Kingdom census, 2021 census. The city was founded under the name of Eboracum in AD 71. It then became the capital of Britannia Inferior, a province of the Roman Empire, and was later the capital of the kingdoms of Deira, Northumbria and Jórvík, Scandinavian York. In the England in the Middle Ages, Middle Ages it became the Province of York, northern England ...
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AbC-19 Rapid Antibody Test
The AbC-19 rapid antibody test is an immunological test for COVID-19 exposure developed by the UK Rapid Test Consortium and manufactured by Abingdon Health. It uses a lateral flow test to determine whether a person has IgG antibodies to the SARS-CoV-2 virus that causes COVID-19. The test uses a single drop of blood obtained from a finger prick and yields results in 20 minutes. The sensitivity of this test is 98.03% while the specificity is 99.56%. This test is paired with an easy-to-use mobile app which allows a trained professional to generate an antibody test certificate for storing on a person's smartphone. See also * COVID-19 rapid antigen test COVID-19 rapid antigen tests or RATs, also frequently called COVID-19 lateral flow tests or LFTs, are rapid antigen tests used to detect Severe acute respiratory syndrome coronavirus 2, SARS-CoV-2 infection (COVID-19). They are quick to implemen ... References External links Official website AbC 19 Rapid Test Instructions ...
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Long COVID
Long may refer to: Measurement * Long, characteristic of something of great duration * Long, characteristic of something of great length * Longitude (abbreviation: long.), a geographic coordinate * Longa (music), note value in early music mensural notation Places Asia * Long District, Laos * Long District, Phrae, Thailand * Longjiang (other) or River Long (lit. "dragon river"), one of several rivers in China * Yangtze River or Changjiang (lit. "Long River"), China Elsewhere * Long, Somme, France People * Long (Chinese surname) * Long (Western surname) Fictional characters * Long (''Bloody Roar''), in the video game series * Long, Aeon of Permanence in Honkai: Star Rail Sports * Long, a fielding term in cricket * Long, in tennis and similar games, beyond the service line during a serve and beyond the baseline during play Other uses * , a U.S. Navy ship name * Long (finance), a position in finance, especially stock markets * Lòng, name for a laneway in Sh ...
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UK Biobank
UK Biobank is a long-term prospective biobank study in the United Kingdom (UK) that houses the de-identified biological samples and health-related data of half a million people. The volunteer participants aged 40-69 were recruited between 2006 and 2010 from across Great Britain and consented to both share their health data and to be followed for at least 30 years thereafter; with the aim to enable scientific discoveries into the prevention, diagnosis, and treatment of disease. Background Based in Stockport, Greater Manchester, UK Biobank is incorporated as a limited company and Charity Commission for England and Wales, registered charity in England and Wales, and Office of the Scottish Charity Regulator, registered as a charity in Scotland. UK Biobank holds more than 10,000 variables of data on many of their 500,000 participants to inform research including biological samples, physical measurements, body and brain imaging data, bone density data, activity tracking and lifesty ...
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Department Of Health And Social Care
The Department of Health and Social Care (DHSC) is a ministerial department of the Government of the United Kingdom. It is responsible for government policy on health and adult social care matters in England, along with a few elements of the same matters which are not otherwise devolved to the Scottish Government, Welsh Government or Northern Ireland Executive. It oversees the English National Health Service (NHS). The department is led by the Secretary of State for Health and Social Care with three ministers of state and three parliamentary under-secretaries of state. The department develops policies and guidelines to improve the quality of care and to meet patient expectations. It carries out some of its work through arms-length bodies (ALBs), including executive non-departmental public bodies such as NHS England and the NHS Digital, and executive agencies such as the UK Health Security Agency and the Medicines and Healthcare products Regulatory Agency (MHRA). The ...
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European Union
The European Union (EU) is a supranational union, supranational political union, political and economic union of Member state of the European Union, member states that are Geography of the European Union, located primarily in Europe. The union has a total area of and an estimated population of over 449million as of 2024. The EU is often described as a ''sui generis'' political entity combining characteristics of both a federation and a confederation. Containing 5.5% of the world population in 2023, EU member states generated a nominal gross domestic product (GDP) of around €17.935 trillion in 2024, accounting for approximately one sixth of global economic output. Its cornerstone, the European Union Customs Union, Customs Union, paved the way to establishing European Single Market, an internal single market based on standardised European Union law, legal framework and legislation that applies in all member states in those matters, and only those matters, where the states ...
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UK Rapid Test Consortium
The UK Rapid Test Consortium (UK-RTC) is a United Kingdom industry consortium created to produce a lateral flow rapid test for COVID-19. Rapid tests are a form of COVID-19 testing technology that was originally developed from significant investment by the United Kingdom government to develop new forms of COVID-19 testing that provided advantages over existing forms such as PCR. Its members include Abingdon Health, BBI Solutions, CIGA Healthcare, Omega Diagnostics, and Oxford University. In 2020, the consortium developed the AbC-19 rapid antibody test to meet UK government requirements. The government ordered 1 million of the UK-RTC's rapid tests in October 2020. CIGA Healthcare was made responsible for assembly and distribution, and was awarded distribution to the United States in November 2020 after approval was given by the FDA The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services. The FDA ...
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Coronavirus Spike Protein
Spike (S) glycoprotein (sometimes also called spike protein, formerly known as E2) is the largest of the four major structural proteins found in coronaviruses. The spike protein assembles into trimers that form large structures, called spikes or peplomers, that project from the surface of the virion. The distinctive appearance of these spikes when visualized using negative stain transmission electron microscopy, "recalling the solar corona", gives the virus family its main name. The function of the spike glycoprotein is to mediate viral entry into the host cell by first interacting with molecules on the exterior cell surface and then fusing the viral and cellular membranes. Spike glycoprotein is a class I fusion protein that contains two regions, known as S1 and S2, responsible for these two functions. The S1 region contains the receptor-binding domain that binds to receptors on the cell surface. Coronaviruses use a very diverse range of receptors; HCoV-NL63, SARS-CoV ( ...
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SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is a strain of coronavirus that causes COVID-19, the respiratory illness responsible for the COVID-19 pandemic. The virus previously had the Novel coronavirus, provisional name 2019 novel coronavirus (2019-nCoV), and has also been called human coronavirus 2019 (HCoV-19 or hCoV-19). First identified in the city of Wuhan, Hubei, China, the World Health Organization designated the outbreak a public health emergency of international concern from January 30, 2020, to May 5, 2023. SARS‑CoV‑2 is a positive-sense single-stranded RNA virus that is Contagious disease, contagious in humans. SARS‑CoV‑2 is a strain of the species ''Betacoronavirus pandemicum'' (SARSr-CoV), as is SARS-CoV-1, the virus that caused the 2002–2004 SARS outbreak. There are animal-borne coronavirus strains more closely related to SARS-CoV-2, the most closely known relative being the BANAL-52 bat coronavirus. SARS-CoV-2 is of Zoonosis, z ...
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IgG Antibodies
Immunoglobulin G (IgG) is a type of antibody. Representing approximately 75% of serum antibodies in humans, IgG is the most common type of antibody found in blood circulation. IgG molecules are created and released by plasma B cells. Each IgG antibody has two paratopes. Function Antibodies are major components of humoral immunity. IgG is the main type of antibody found in blood and extracellular fluid, allowing it to control infection of body tissues. By binding many kinds of pathogens such as viruses, bacteria, and fungi, IgG protects the body from infection. It does this through several mechanisms: * IgG-mediated binding of pathogens causes their immobilization and binding together via agglutination; IgG coating of pathogen surfaces (known as opsonization) allows their recognition and ingestion by phagocytic immune cells leading to the elimination of the pathogen itself; * IgG activates the classical pathway of the complement system, a cascade of immune protein production ...
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COVID-19 Pandemic
The COVID-19 pandemic (also known as the coronavirus pandemic and COVID pandemic), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), began with an disease outbreak, outbreak of COVID-19 in Wuhan, China, in December 2019. Soon after, it spread to other areas of Asia, and COVID-19 pandemic by country and territory, then worldwide in early 2020. The World Health Organization (WHO) declared the outbreak a public health emergency of international concern (PHEIC) on 30 January 2020, and assessed the outbreak as having become a pandemic on 11 March. COVID-19 symptoms range from asymptomatic to deadly, but most commonly include fever, sore throat, nocturnal cough, and fatigue. Transmission of COVID-19, Transmission of the virus is often airborne transmission, through airborne particles. Mutations have variants of SARS-CoV-2, produced many strains (variants) with varying degrees of infectivity and virulence. COVID-19 vaccines were developed rapidly and deplo ...
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Lateral Flow Assay
A lateral flow test (LFT), is an assay also known as a lateral flow immunochromatographic test (ICT), or rapid test. It is a simple device intended to detect the presence of a target substance in a liquid sample without the need for specialized and costly equipment. LFTs are widely used in medical diagnostics in the home, at the point of care, and in the laboratory. For instance, the home pregnancy test is an LFT that detects a specific hormone. These tests are simple and economical and generally show results in around five to thirty minutes. Many lab-based applications increase the sensitivity of simple LFTs by employing additional dedicated equipment. Because the target substance is often a biological antigen, many lateral flow tests are rapid antigen tests (RAT or ART). LFTs operate on the same principles of affinity chromatography as the enzyme-linked immunosorbent assays (ELISA). In essence, these tests run the liquid sample along the surface of a pad with reactive molecules ...
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