ATC Code M01

	ATC Code M01 M01A Anti-inflammatory and antirheumatic products, non-steroids M01AA Butylpyrazolidines :M01AA01 Phenylbutazone :M01AA02 Mofebutazone :M01AA03 Oxyphenbutazone :M01AA05 Clofezone :M01AA06 Kebuzone :QM01AA90 Suxibuzone :QM01AA99 Combinations M01AB Acetic acid derivatives and related substances :M01AB01 Indometacin :M01AB02 Sulindac :M01AB03 Tolmetin :M01AB04 Zomepirac :M01AB05 Diclofenac :M01AB06 Alclofenac :M01AB07 Bumadizone :M01AB08 Etodolac :M01AB09 Lonazolac :M01AB10 Fentiazac :M01AB11 Acemetacin :M01AB12 Difenpiramide :M01AB13 Oxametacin :M01AB14 Proglumetacin :M01AB15 Ketorolac :M01AB16 Aceclofenac :M01AB17 Bufexamac :M01AB51 Indometacin, combinations :M01AB55 Diclofenac, combinations M01AC Oxicams :M01AC01 Piroxicam :M01AC02 Tenoxicam :M01AC04 Droxicam :M01AC05 Lornoxicam :M01AC06 Meloxicam :M01AC56 Meloxicam, combinations M01AE Propionic acid derivatives :M01AE01 Ibuprofen :M01AE02 Naproxen :M01AE03 Ketoprofen :M01AE04 Fenoprofen :M01AE05 Fenbufen :M01AE06 Benoxaprofen : ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Anti-inflammatory Anti-inflammatory is the property of a substance or treatment that reduces inflammation, fever or swelling. Anti-inflammatory drugs, also called anti-inflammatories, make up about half of analgesics. These drugs reduce pain by inhibiting mechanisms of inflammation, as opposed to opioids, which affect the central nervous system to block pain. Common anti-inflammatory drugs include nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, antileukotrienes, and monoclonal antibodies. Drugs Clinically approved Nonsteroidal anti-inflammatory drugs NSAIDs alleviate pain by counteracting the cyclooxygenase (COX) enzyme involved in pain mechanisms. Some common examples of NSAIDs are aspirin, ibuprofen, and naproxen. Selective COX-2 inhibitors, such as celecoxib, block the enzymatic conversion of arachidonic acid into prostaglandin, inhibiting inflammation and pain. Analgesics commonly associated with anti-inflammatory drugs, such as acetaminophen (paracetamol), hav ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Bumadizone Bumadizone, or bumazidone, is a nonsteroidal anti-inflammatory drug Non-steroidal anti-inflammatory drugs (NSAID) are members of a Indication (medicine), therapeutic drug class which Analgesic, reduces pain, Anti-inflammatory, decreases inflammation, Antipyretic, decreases fever, and Antithrombotic, prevents bl ... (NSAID). References Hydrazides Nonsteroidal anti-inflammatory drugs {{musculoskeletal-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Tenoxicam Tenoxicam, sold under the brand name Mobiflex among others, is a nonsteroidal anti-inflammatory drug (NSAID). It is used to relieve inflammation, swelling, stiffness, and pain associated with rheumatoid arthritis, osteoarthritis, ankylosing spondylitis (a type of arthritis involving the spine), tendinitis (inflammation of a tendon), bursitis (inflammation of a bursa, a fluid-filled sac located around joints and near the bones), and periarthritis of the shoulders or hips (inflammation of tissues surrounding these joints). Tenoxicam belongs to the class of NSAIDs known as oxicams. It was patented in 1974 by Roche and approved for medical use in 1987. It is available as a prescription-only drug in the United Kingdom and other countries, but not in the US. Outside the United Kingdom, tenoxicam is also marketed under brand names including Tilatil, Tilcitin, and Alganex. Contraindications The drug is contraindicated for patients who are seniors who have been given anesthesia or ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Piroxicam Piroxicam is a nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class used to relieve the symptoms of painful inflammatory conditions like arthritis. Piroxicam works by preventing the production of endogenous prostaglandins which are involved in the mediation of pain, stiffness, tenderness and swelling. The medicine is available as capsule (pharmacy), capsules, tablet (pharmacy), tablets and, in some countries, as a prescription-free gel 0.5%. It is also available in a betadex formulation, which allows a more rapid absorption of piroxicam from the digestive tract. Piroxicam is one of the few NSAIDs that can be given parenteral routes. It was patented in 1968 by Pfizer and approved for medical use in 1979. It became generic in 1992, and is marketed worldwide under many brand names. Medical uses It is used in the treatment of certain inflammatory conditions like rheumatoid arthritis, rheumatoid and osteoarthritis, primary dysmenorrhoea, and postoperative pain; it acts as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
picture info	Oxicam Oxicam is a class of non-steroidal anti-inflammatory drugs (NSAIDs), meaning that they have anti-inflammatory, analgesic, and antipyretic therapeutic effects. Oxicams bind closely to plasma proteins. Most oxicams are unselective inhibitors of the cyclooxygenase (COX) enzymes. The exception is meloxicam with a slight (10:1) preference for COX-2, which, however, is only clinically relevant at low doses. The most popular drug of the oxicam class is piroxicam. Other examples include: ampiroxicam, droxicam, pivoxicam, tenoxicam, lornoxicam, and meloxicam. Isoxicam has been suspended as a result of fatal skin reactions. Chemistry The physico-chemical characteristics of these molecules vary greatly depending upon the environment. In contrast to most other NSAIDs, oxicams are not carboxylic acids. They are Tautomer, tautomeric, and can exist as a number of tautomers (keto-enol tautomerism), here exemplified by piroxicam: Side effects The oxicams are associated with drug-related ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Bufexamac Bufexamac is a drug used as an anti-inflammatory agent on the skin, as well as rectally. Common brand names include Paraderm and Parfenac. It was withdrawn in Europe and Australia because of allergic reactions. Indications Ointments and lotions containing bufexamac are used for the treatment of subacute and chronic eczema of the skin, including atopic eczema, as well as sunburn and other minor burns, and itching. Suppositories containing bufexamac in combination with local anaesthetics are used against haemorrhoids. Pharmacology Bufexamac is thought to act by inhibiting the enzyme cyclooxygenase, which would make it a non-steroidal anti-inflammatory drug. Evidence on the mechanism of action is scarce. Furthermore, bufexamac was identified as a specific inhibitor of class IIB histone deacetylases ( HDAC6 and HDAC10). Side effects Bufexamac can cause severe contact dermatitis which is often hard to distinguish from the initial condition. As a consequence, the European Medicines ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Aceclofenac Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) analog of diclofenac. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. It was patented in 1983 and approved for medical use in 1992. Side effects Aceclofenac should not be given to people with porphyria or breast-feeding mothers, and is not recommended for children. It should be avoided near term in a pregnant woman because of the risk of having a premature closure of ductus arteriosus leading to fetal hydrops in the neonate. Chemistry Aceclofenac (C16H13Cl2NO4), chemically 2- phenylacetooxyacetic acid is a crystalline powder with a molecular weight of 354.19. It is practically insoluble in water with good permeability. It is metabolized in human hepatocytes and human microsomes to form -(2',6'-dichloro-4'-hydroxy- phenylamino) phenylacetoxyacetic acid as the major metabolite, which is then further conjugated. According to the Biopharmaceutical ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Ketorolac Ketorolac, sold under the brand name Toradol, Acular and Sprix, among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain. Specifically it is recommended for moderate to severe pain. Recommended duration of treatment is less than six days, and in Switzerland not more than seven days (parenterally two days). It is used by mouth, by nose, by injection into a vein or intramuscular, muscle, and as eye drops. Effects begin within an hour and last for up to eight hours. Ketorolac also has antipyretic (fever-reducing) properties. Common side effects include sleepiness, dizziness, abdominal pain, swelling, and nausea. Serious side effects may include stomach bleeding, kidney failure, heart attacks, bronchospasm, heart failure, and anaphylaxis. Use is not recommended during the last part of pregnancy or during breastfeeding. Ketorolac works by blocking cyclooxygenase 1 and 2 (COX1 and COX2), thereby decreasing production of prostaglandins. Ketorolac was patented ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Proglumetacin Proglumetacin (usually as the maleate salt, trade names Afloxan, Protaxon and Proxil) is a nonsteroidal anti-inflammatory drug (NSAID). It is metabolized in the body to indometacin and proglumide Proglumide, sold under the brand name Milid, is a drug that inhibits gastrointestinal motility Motility is the ability of an organism to move independently using metabolism, metabolic energy. This biological concept encompasses movement at v ..., a drug with antisecretory effects that helps prevent injury to the stomach lining. References Dipropylamino compounds Nonsteroidal anti-inflammatory drugs Prodrugs Indole ethers at the benzene ring Piperazines Carboxylate esters Benzamides {{musculoskeletal-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Oxametacin Oxametacin (or oxamethacin) is a non-steroidal anti-inflammatory drug Non-steroidal anti-inflammatory drugs (NSAID) are members of a therapeutic drug class which reduces pain, decreases inflammation, decreases fever, and prevents blood clots. Side effects depend on the specific drug, its dose and duration of .... Hydrolysis of the amide group is one of the synthetic pathways to DeboxametChemDrug. References Benzamides 4-Chlorophenyl compounds Hydroxamic acids 5-Methoxytryptamines Nonsteroidal anti-inflammatory drugs Phenol ethers {{musculoskeletal-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Difenpiramide Difenpiramide is a non-steroidal anti-inflammatory drug Non-steroidal anti-inflammatory drugs (NSAID) are members of a therapeutic drug class which reduces pain, decreases inflammation, decreases fever, and prevents blood clots. Side effects depend on the specific drug, its dose and duration of .... References 2-Pyridyl compounds Acetamides Nonsteroidal anti-inflammatory drugs {{musculoskeletal-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
picture info	Acemetacin Acemetacin is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, lower back pain, and relieving post-operative pain. It is manufactured by Merck KGaA under the tradename Emflex. It is no longer available in the UK (since 2018), however is available in other countries as a prescription-only drug. Medical uses Acemetacin has proven effective in the treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and other kinds of rheumatoid inflammation, as well as in post-operative and post-traumatic pain and attack of gout. Application of a single dose of acemetacin for post-operative pain is not well supported by studies. Contraindications Contraindications are basically the same as with other NSAIDs: hypersensitivity reactions to NSAIDs in the past (typically asthma or skin reactions), gastrointestinal or cerebral bleeding, peptic ulcer, haematopoietic disorders (anaemia, leukopenia), and during the th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]