Proglumetacin
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Proglumetacin (usually as the
maleate Maleic acid or ''cis''-butenedioic acid is an organic compound that is a dicarboxylic acid, a molecule with two carboxyl groups. Its chemical formula is HO2CCH=CHCO2H. Maleic acid is the ''cis'' isomer of butenedioic acid, whereas fumaric acid ...
salt, trade names Afloxan, Protaxon and Proxil) is a
nonsteroidal anti-inflammatory drug Non-steroidal anti-inflammatory drugs (NSAID) are members of a Indication (medicine), therapeutic drug class which Analgesic, reduces pain, Anti-inflammatory, decreases inflammation, Antipyretic, decreases fever, and Antithrombotic, prevents bl ...
(NSAID). It is
metabolized Metabolism (, from ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run cellular processes; the co ...
in the body to
indometacin Indometacin, also known as indomethacin, is a nonsteroidal anti-inflammatory drug (NSAID) commonly used as a prescription medication to reduce fever, pain, stiffness, and swelling from inflammation. It works by inhibiting the production of ...
and
proglumide Proglumide, sold under the brand name Milid, is a drug that inhibits gastrointestinal motility Motility is the ability of an organism to move independently using metabolism, metabolic energy. This biological concept encompasses movement at v ...
, a drug with antisecretory effects that helps prevent injury to the stomach lining.


References

Dipropylamino compounds Nonsteroidal anti-inflammatory drugs Prodrugs Indole ethers at the benzene ring Piperazines Carboxylate esters Benzamides {{musculoskeletal-drug-stub