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ADAP Advocacy
ADAP Advocacy is an American national 501(c)(3) non-profit organization based in Washington, D.C., that is dedicated to promoting and enhancing the AIDS Drug Assistance Programs (ADAPs) and improving access to care and treatment for Persons Living with HIV/AIDS (PLWHA) in the United States and the U.S. Territories. History ADAP Advocacy (formerly the ADAP Advocacy Association, or aaa+) began as an organizing committee in 2007 composed of advocates, community leaders, students, medical specialists, and ADAP recipients in response to the then long-standing waiting list crisis facing the Ryan White HIV/AIDS Program (RWHAP), commonly known as the ADAP Crisis. The ADAP Crisis resulted in tens of thousands of Persons Living with HIV/AIDS (PLWHA) being unable to access medications to treat their HIV across the United States, peaking in September 2011 with 9,298 individuals on ADAP waiting lists. Throughout most of the 2000s and early 2010s, state ADAPs were forced to place fi ...
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501(c)(3) Organization
A 501(c)(3) organization is a United States corporation, trust, unincorporated association or other type of organization exempt from federal income tax under section 501(c)(3) of Title 26 of the United States Code. It is one of the 29 types of 501(c) nonprofit organizations in the US. 501(c)(3) tax-exemptions apply to entities that are organized and operated exclusively for religious, charitable, scientific, literary or educational purposes, for testing for public safety, to foster national or international amateur sports competition, or for the prevention of cruelty to children or animals. 501(c)(3) exemption applies also for any non-incorporated community chest, fund, cooperating association or foundation organized and operated exclusively for those purposes.
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Hepatitis C
Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver; it is a type of viral hepatitis. During the initial infection people often have mild or no symptoms. Occasionally a fever, dark urine, abdominal pain, and yellow tinged skin occurs. The virus persists in the liver in about 75% to 85% of those initially infected. Early on, chronic infection typically has no symptoms. Over many years however, it often leads to liver disease and occasionally cirrhosis. In some cases, those with cirrhosis will develop serious complications such as liver failure, liver cancer, or dilated blood vessels in the esophagus and stomach. HCV is spread primarily by blood-to-blood contact associated with injection drug use, poorly sterilized medical equipment, needlestick injuries in healthcare, and transfusions. Using blood screening, the risk from a transfusion is less than one per two million. It may also be spread from an infected mother to h ...
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Pre-exposure Prophylaxis
Pre-exposure prophylaxis (PrEP) is the use of medications to prevent the spread of disease in people who have not yet been exposed to a disease-causing agent, usually a virus. The term typically refers to the use of antiviral drugs as a strategy for the prevention of HIV/AIDS. PrEP is one of a number of HIV prevention strategies for people who are HIV negative but who have a higher risk of acquiring HIV, including sexually active adults at increased risk of contracting HIV, people who engage in intravenous drug use (see drug injection), and serodiscordant sexually active couples. When used as directed, PrEP has been shown to be highly effective, reducing the risk of acquiring HIV by up to 99%. , the World Health Organization (WHO) recommends two drug combinations for the use as PrEP for HIV/AIDS: the combination of tenofovir disoproxil and emtricitabine (Truvada), or the combination of tenofovir disoproxil and lamivudine (Cimduo). In October 2019, the US Food and Drug Admi ...
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COVID-19
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first known case was identified in Wuhan, China, in December 2019. The disease quickly spread worldwide, resulting in the COVID-19 pandemic. The symptoms of COVID‑19 are variable but often include fever, cough, headache, fatigue, breathing difficulties, loss of smell, and loss of taste. Symptoms may begin one to fourteen days after exposure to the virus. At least a third of people who are infected do not develop noticeable symptoms. Of those who develop symptoms noticeable enough to be classified as patients, most (81%) develop mild to moderate symptoms (up to mild pneumonia), while 14% develop severe symptoms ( dyspnea, hypoxia, or more than 50% lung involvement on imaging), and 5% develop critical symptoms ( respiratory failure, shock, or multiorgan dysfunction). Older people are at a higher risk of developing ...
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Medicare (United States)
Medicare is a government national health insurance program in the United States, begun in 1965 under the Social Security Administration (SSA) and now administered by the Centers for Medicare and Medicaid Services (CMS). It primarily provides health insurance for Americans aged 65 and older, but also for some younger people with disability status as determined by the SSA, including people with end stage renal disease and amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease). In 2018, according to the 2019 Medicare Trustees Report, Medicare provided health insurance for over 59.9 million individuals—more than 52 million people aged 65 and older and about 8 million younger people. According to annual Medicare Trustees reports and research by the government's MedPAC group, Medicare covers about half of healthcare expenses of those enrolled. Enrollees almost always cover most of the remaining costs by taking additional private insurance and/or by joining a public Part C o ...
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Affordable Care Act
The Affordable Care Act (ACA), formally known as the Patient Protection and Affordable Care Act and colloquially known as Obamacare, is a landmark U.S. federal statute enacted by the 111th United States Congress and signed into law by President Barack Obama on March 23, 2010. Together with the Health Care and Education Reconciliation Act of 2010 amendment, it represents the U.S. healthcare system's most significant regulatory overhaul and expansion of coverage since the enactment of Medicare and Medicaid in 1965. The ACA's major provisions came into force in 2014. By 2016, the uninsured share of the population had roughly halved, with estimates ranging from 20 to 24 million additional people covered. The law also enacted a host of delivery system reforms intended to constrain healthcare costs and improve quality. After it went into effect, increases in overall healthcare spending slowed, including premiums for employer-based insurance plans. The increased coverage was du ...
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Public Service Announcement
A public service announcement (PSA) is a message in the public interest disseminated by the media without charge to raise public awareness and change behavior. In the UK, they are generally called a public information film (PIF); in Hong Kong, they are known as an announcement in the public interest (API). History The earliest public service announcements (in the form of moving pictures) were made before and during the Second World War years in both the UK and the US. In the UK, amateur actor Richard Massingham set up Public Relationship Films Ltd in 1938 as a specialist agency for producing short educational films for the public. In the films, he typically played a bumbling character who was slightly more stupid than average and often explained the message of the film by demonstrating the risks if it was ignored. The films covered topics such as how to cross the road, how to prevent the spread of diseases, how to swim, and how to drive without causing the road to be unsafe f ...
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Counterfeit Medications
A counterfeit medication or a counterfeit drug is a medication or pharmaceutical item which is produced and sold with the intent to deceptively represent its origin, authenticity, or effectiveness. A counterfeit drug may contain inappropriate quantities of active ingredients, or none, may be improperly processed within the body (''e.g.'', absorption by the body), may contain ingredients that are not on the label (which may or may not be harmful), or may be supplied with inaccurate or fake packaging and labeling. Counterfeit drugs are related to pharma fraud. Drug manufacturers and distributors are increasingly investing in countermeasures, such as traceability and authentication technologies, to try to minimise the impact of counterfeit drugs. Antibiotics with insufficient quantities of an active ingredient add to the problem of antibiotic resistance. Legitimate, correctly labeled, low-cost generic drugs are not counterfeit or fake (although they can be counterfeited much as b ...
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340B Drug Pricing Program
The 340B Drug Pricing Program is a US federal government program created in 1992 that requires drug manufacturers to provide outpatient drugs to eligible health care organizations and covered entities at significantly reduced prices. The intent of the program is to allow covered entities to ''"stretch scarce federal resources as far as possible, reaching more eligible patients and providing more comprehensive services."''Veterans Health Care Act of 1992, Pub. L. No. 102-585 § 602, 106 Stat. 4943, 4967-4971 (1992).GAO, Drug Pricing: Manufacturer Discounts in the 340B Program Offer Benefits, but Federal Oversight Needs Improvement, GAO (Washington, D.C.: Sep. 2011) at 1 ereafter referred to as GAO 340B Report Maintaining services and lowering medication costs for patients is consistent with the purpose of the program, which is named for the section authorizing it in the Public Health Service Act (PHSA) It was enacted by Congress as part of a larger bill signed into law by President ...
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Direct-acting Antivirals
Direct-acting antivirals (DAA) are drugs used to treat hepatitis C infections. They are a combination of antiviral drugs that target stages of the hepatitis C virus reproductive cycle. They are more effective than older treatments such as ribavirin and interferon. The DAA drugs are taken orally, as tablets, for 8 to 12 weeks. The treatment depends on the type or types (genotypes) of hepatitis C virus that are causing the infection. Both during and at the end of treatment, blood tests are used to monitor the effectiveness of the treatment and subsequent cure. The DAA combination drugs used include: * Harvoni (sofosbuvir and ledipasvir) * Epclusa (sofosbuvir and velpatasvir) * Vosevi (sofosbuvir, velpatasvir, and voxilaprevir) * Zepatier (elbasvir and grazoprevir) * Mavyret (glecaprevir and pibrentasvir) DAAs were approved on the basis of a surrogate endpoint In clinical trials, a surrogate endpoint (or surrogate marker) is a measure of effect of a specific treatment that may ...
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Richard Burr
Richard Mauze Burr (born November 30, 1955) is an American businessman and politician who is the senior United States senator from North Carolina, serving since 2005. A member of the Republican Party, Burr was previously a member of the United States House of Representatives. Born in Charlottesville, Virginia, Burr is a graduate of Wake Forest University. Before seeking elected office, he was a sales manager for a lawn equipment company. In 1994, he was elected to the U.S. House of Representatives for North Carolina's 5th congressional district as part of the Republican Revolution. Burr was first elected to the United States Senate in 2004. From 2015 to 2020, he chaired the Senate Intelligence Committee. In 2016, he announced that he would not seek reelection in 2022. Burr temporarily stepped down as chair of the Intelligence Committee on May 15, 2020, amid an FBI investigation into allegations of insider trading during the COVID-19 pandemic. On January 19, 2021, the Dep ...
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AIDS Drug Assistance Programs
AIDS Drug Assistance Programs are a set of programs in all 50-states in the United States that provide Food and Drug Administration-approved HIV treatment drugs to low income patients in the U.S. The programs are administered by each state with funds distributed by the United States government. In June 2007 the program provided coverage for 102,000 or 30% of those infected with HIV in the United States. Drug expenditures were $100.1 million in 2007 and $8.8 million in money spent on helping with insurance payments. This represented 344,600 prescriptions. The total program budget is $1.4 Billion with California receiving $288 Million, New York $241 Million, Texas $101 Million, and Florida $97 Million. The program first began in 1987 with appropriations to help pay for AZT. The program was expanded in 1990 with the Ryan White Comprehensive AIDS Resources Emergency (CARE) Act (commonly referred to as the Ryan White Care Act. Most recipients are below 200% of the Federal Poverty L ...
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