ACE Mixture
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ACE Mixture
ACE mixture is an historical anaesthetic agent for general anaesthesia. It was first suggested by George Harley and first used in England around 1860. In 1864 it was recommended for use by the Royal Medical and Surgical Society's Chloroform Committee. It was rarely used after the 19th century, except in Germany, where it was used for slightly longer. It was a mixture of alcohol, chloroform Chloroform, or trichloromethane (often abbreviated as TCM), is an organochloride with the formula and a common solvent. It is a volatile, colorless, sweet-smelling, dense liquid produced on a large scale as a precursor to refrigerants and po ... and Diethyl ether#Anesthetic use, ether which gives the mixture its name. Its effects were said to be between that of chloroform and ether and it was used when ether alone was contraindicated. Its boiling point was given as . Its actual safety margin over its components alone was marginal. Usage ACE mixture was most commonly made up in the rati ...
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Anesthetic
An anesthetic (American English) or anaesthetic (British English; see spelling differences) is a drug used to induce anesthesia ⁠— ⁠in other words, to result in a temporary loss of sensation or awareness. They may be divided into two broad classes: general anesthetics, which result in a reversible loss of consciousness, and local anesthetics, which cause a reversible loss of sensation for a limited region of the body without necessarily affecting consciousness. A wide variety of drugs are used in modern anesthetic practice. Many are rarely used outside anesthesiology, but others are used commonly in various fields of healthcare. Combinations of anesthetics are sometimes used for their synergistic and additive therapeutic effects. Adverse effects, however, may also be increased. Anesthetics are distinct from analgesics, which block only sensation of painful stimuli. Analgesics are typically used in conjunction with anesthetics to control pre-, intra-, and postop ...
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Dichloromethane
Dichloromethane (DCM, methylene chloride, or methylene bichloride) is an organochlorine compound with the formula . This colorless, volatile liquid with a chloroform-like, sweet odor is widely used as a solvent. Although it is not miscible with water, it is slightly polar, and miscible with many organic solvents.Rossberg, M. ''et al.'' (2006) "Chlorinated Hydrocarbons" in Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH, Weinheim. . Occurrence Natural sources of dichloromethane include oceanic sources, macroalgae, wetlands, and volcanoes. However, the majority of dichloromethane in the environment is the result of industrial emissions. Production DCM is produced by treating either chloromethane or methane with chlorine gas at 400–500 °C. At these temperatures, both methane and chloromethane undergo a series of reactions producing progressively more chlorinated products. In this way, an estimated 400,000 tons were produced in the US, Europe, and Japan in 199 ...
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Anesthesia
Anesthesia (American English) or anaesthesia (British English) is a state of controlled, temporary loss of sensation or awareness that is induced for medical or veterinary purposes. It may include some or all of analgesia (relief from or prevention of pain), paralysis (muscle relaxation), amnesia (loss of memory), and unconsciousness. An individual under the effects of anesthetic drugs is referred to as being anesthetized. Anesthesia enables the painless performance of procedures that would otherwise require physical restraint in a non-anesthetized individual, or would otherwise be technically unfeasible. Three broad categories of anesthesia exist: * ''General anesthesia'' suppresses central nervous system activity and results in unconsciousness and total lack of Sensation (psychology), sensation, using either injected or inhaled drugs. * ''Sedation'' suppresses the central nervous system to a lesser degree, inhibiting both anxiolysis, anxiety and creation of long-term memory, ...
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Flickr
Flickr ( ) is an image hosting service, image and Online video platform, video hosting service, as well as an online community, founded in Canada and headquartered in the United States. It was created by Ludicorp in 2004 and was previously a common way for amateur and professional photographers to host high-resolution photos. It has changed ownership several times and has been owned by SmugMug since April 20, 2018. Flickr had a total of 112 million registered members and more than 3.5 million new images uploaded daily. On August 5, 2011, the site reported that it was hosting more than 6 billion images. In 2024, it was reported as having shared 10 billion photos and accepting 25 million per day. Photos and videos can be accessed from Flickr without the need to register an account, but an account must be made to upload content to the site. Registering an account also allows users to create a profile page containing photos and videos that the user has uploaded and also grants the ...
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Compound Spirit Of Ether
Compound spirit of ether, also called Hoffmann's anodyne, Hoffmann's drops, or aetheris spiritus compositus, is a solution of one part diethyl ether in three parts alcohol. It is used traditionally as an anodyne or as a hypnotic. Its use as a drug was introduced by Friedrich Hoffmann Friedrich Hoffmann or Hofmann (19 February 1660 – 12 November 1742) was a German physician and chemist. He is also sometimes known in English as Frederick Hoffmann. Life His family had been connected with medicine for 200 years before him. Bo ....T. Kleij: ''Zur Entwicklungs- und Herstellungsgeschichte der "Hoffmannstropfen" und ihrer Darstellung und Interpretation in den medizinischen Werken des 19. und 20. Jahrhunderts''. Dresden, 2003. References Traditional medicine {{nervous-system-drug-stub ...
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James Tayloe Gwathmey
James Tayloe Gwathmey, M.D. (September 10, 1862—February 11, 1944) was an American physician and the first president of the American Association of Anesthetics (now the International Anesthesia Research Society). A pioneer of early anesthetic devices for medical use, he co-authored the first comprehensive textbook on the subject of medical anesthetics, titled ''Anesthesia'', which was published in 1914. For this and other contributions to anesthesiology, which included innovations in administering anesthetics to war wounded and in obstetrics, Gwathmey was hailed at the time of his death as the "Father of Modern Anesthesia." Biography Early life Gwathmey was born on September 10, 1862, at Buena Vista in Roanoke, Virginia, the childhood home of his mother, Mary Lavinia Tayloe, daughter of George Plater Tayloe and Mary Elizabeth Langhorne. He was a student at the Norfolk Male Academy and later attended the Virginia Military Institute. The third year of his college education w ...
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Clover's Inhaler
Joseph Thomas Clover (born 28 February 1825; baptised 7 May 1825 – 27 September 1882) was an English doctor and innovator of anaesthesia. He invented a variety of pieces of apparatus to deliver anaesthetics, including ether and chloroform, safely and controllably. By 1871, he had administered anaesthetics 13,000 times without a fatality. Clover assisted at surgery of public figures including Napoleon III, Princess Alexandra of Denmark and her husband King Edward VII (then Prince of Wales), Sir Robert Peel, and Florence Nightingale. His inventions included the bulky 'Clover's chloroform apparatus' (1862), with which he was often photographed; and the compact 'Clover's portable regulating ether inhaler' (1877), which remained in use well into the 20th century. With fellow innovator John Snow, Clover is one of the supporters on the crest of the Royal College of Anaesthetists. Early life Clover was born in the town of Aylsham, NorfolkRushman, page 27. to John Wright Clover, a ...
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Towel
A towel () is a piece of absorption (chemistry), absorbent cloth or paper used for drying or wiping a surface. Towels draw moisture through direct contact. Bathing towels and hand towels are usually made of cotton, linen, bamboo and Microfiber, synthetic microfibers. In households, several types of towels are used, such as hand towels, bath towels, and Dishtowel, kitchen towels. Paper towels are provided in commercial or office Bathroom, bathrooms, via a dispenser, for users to dry their hands. They are also used for such duties such as wiping, cleaning, and drying. History According to Middle Ages archaeological studies, "... closely held personal items included the ever present knife and a towel." However, the invention of the towel is commonly associated with the city of Bursa, Turkey, in the 17th century. These Turkish towels began as a flat, woven piece of cotton or linen called a ''peshtamal'', often hand-embroidered. Long enough to wrap around the body, peshtamal were or ...
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Vivisection
Vivisection () is surgery conducted for experimental purposes on a living organism, typically animals with a central nervous system, to view living internal structure. The word is, more broadly, used as a pejorative catch-all term for Animal testing#Definitions, experimentation on live animalsTansey, E.MReview of ''Vivisection in Historical Perspective'' by Nicholaas A. Rupke, book reviews, National Center for Biotechnology Information, p. 226. by organizations opposed to animal experimentation,Yarri, Donna''The Ethics of Animal Experimentation: A Critical Analysis and Constructive Christian Proposal'', Oxford University Press, 2005, p. 163. but the term is rarely used by practicing scientists. Human vivisection, such as live organ procurement, organ harvesting, has been perpetrated as a form of torture. Animal vivisection Regulations and laws Research requiring vivisection techniques that cannot be met through other means is often subject to an external ethics review in con ...
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Carl Ludwig Schleich
Carl Ludwig Schleich (19 July 1859 – 7 March 1922) was a German surgeon and writer. He is best known for his contribution to clinical anesthesia. In addition, he was also a philosopher, poet and painter. Biography Family Schelich's ancestors were a Munich family of prominent painters who had moved to Freienwalde. They included Robert Schleich and Eduard Schleich the Elder. Early life From a very early age, Schleich was exposed to a background in biology. His father was very interested in natural history and the leading theories in the epoch. Later Schleich would recall: In the year 1864, Graefe was a guest in my father's house during the historic conference of biologists, at which Darwin, Haeckel, and Virchow were the mutually hostile protagonists. I, alas, who was only five years of age, was not even aware of this earth-shaking event, since I was lying unconscious in the grip of meningitis. In his childhood, he frequently heard "extremely vigorous" debates about the ...
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Petroleum Ether
Petroleum ether is the petroleum fraction consisting of aliphatic hydrocarbons and boiling in the range 35–60 °C, and commonly used as a laboratory solvent. Despite the name, petroleum ether is not an ether; the term is used only figuratively, signifying extreme lightness and volatility. Properties The very lightest, most volatile liquid hydrocarbon solvents that can be bought from laboratory chemical suppliers may also be offered under the name petroleum ether. Petroleum ether consists mainly of aliphatic hydrocarbons and is usually low in aromatics. It is commonly hydrodesulfurized and may be hydrogenated to reduce the amount of aromatic and other Saturated and unsaturated compounds, unsaturated hydrocarbons. Petroleum ether bears normally a descriptive suffix giving the boiling range. Thus, from the leading international laboratory chemical suppliers it is possible to buy various petroleum ethers with boiling ranges such as 30–50 °C, 40–60 °C, 50–70& ...
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Methanol
Methanol (also called methyl alcohol and wood spirit, amongst other names) is an organic chemical compound and the simplest aliphatic Alcohol (chemistry), alcohol, with the chemical formula (a methyl group linked to a hydroxyl group, often abbreviated as MeOH). It is a light, Volatility (chemistry), volatile, colorless and flammable liquid with a distinctive alcoholic odor similar to that of ethanol (potable alcohol), but is more acutely toxic than the latter. Methanol acquired the name wood alcohol because it was once produced through destructive distillation of wood. Today, methanol is mainly produced industrially by hydrogenation of carbon monoxide. Methanol consists of a methyl group linked to a polar hydroxyl group. With more than 20 million tons produced annually, it is used as a Precursor (chemistry), precursor to other commodity chemicals, including formaldehyde, acetic acid, methyl tert-butyl ether, methyl ''tert''-butyl ether, methyl benzoate, anisole, peroxyacids, ...
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