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A. E. Garrod
Sir Archibald Edward Garrod (25 November 1857 – 28 March 1936) was an English physician who pioneered the field of inborn errors of metabolism. He also discovered alkaptonuria, understanding its inheritance. He served as Regius Professor of Medicine at the University of Oxford from 1920 to 1927.Rolleston, J. D. (2004"Garrod, Sir Archibald Edward (1857–1936)" rev. Alexander G. Bearn, in ''Oxford Dictionary of National Biography'', Oxford University Press. Education and personal life Archibald was the fourth son of Sir Alfred Baring Garrod, a renowned physician who received his medical degree at the age of 23 and became a professor of medicine at University College, London by the time he was 32. He discovered the abnormal uric acid metabolism associated with gout. Garrod's father also successfully estimated the weight of crystals he obtained from a known quantity of blood, resulting in what Garrod called “the first quantitative biochemical investigation made on the livin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
London
London is the Capital city, capital and List of urban areas in the United Kingdom, largest city of both England and the United Kingdom, with a population of in . London metropolitan area, Its wider metropolitan area is the largest in Western Europe, with a population of 14.9 million. London stands on the River Thames in southeast England, at the head of a tidal estuary down to the North Sea, and has been a major settlement for nearly 2,000 years. Its ancient core and financial centre, the City of London, was founded by the Roman Empire, Romans as Londinium and has retained its medieval boundaries. The City of Westminster, to the west of the City of London, has been the centuries-long host of Government of the United Kingdom, the national government and Parliament of the United Kingdom, parliament. London grew rapidly 19th-century London, in the 19th century, becoming the world's List of largest cities throughout history, largest city at the time. Since the 19th cen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Challenger Expedition
The ''Challenger'' expedition of 1872–1876 was a scientific programme that made many discoveries to lay the foundation of oceanography. The expedition was named after the naval vessel that undertook the trip, . The expedition, initiated by William Benjamin Carpenter, was placed under the scientific supervision of Sir Charles Wyville Thomson—of the University of Edinburgh and Merchiston Castle School—assisted by five other scientists, including Sir John Murray (oceanographer), John Murray, a secretary-artist and a photographer. The Royal Society of London obtained the use of ''Challenger'' from the Royal Navy and in 1872 modified the ship for scientific tasks at Sheerness, equipping it with separate laboratories for natural history and chemistry. The expedition, led by Captain George Nares, sailed from Portsmouth, England, on 21 December 1872. Other naval officers included Commander John Maclear. – pages 19 and 20 list the civilian staff and naval officers and crew, along ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diseases Of Children
A disease is a particular abnormal condition that adversely affects the structure or function of all or part of an organism and is not immediately due to any external injury. Diseases are often known to be medical conditions that are associated with specific signs and symptoms. A disease may be caused by external factors such as pathogens or by internal dysfunctions. For example, internal dysfunctions of the immune system can produce a variety of different diseases, including various forms of immunodeficiency, hypersensitivity, allergies, and autoimmune disorders. In humans, ''disease'' is often used more broadly to refer to any condition that causes pain, dysfunction, distress, social problems, or death to the person affected, or similar problems for those in contact with the person. In this broader sense, it sometimes includes injuries, disabilities, disorders, syndromes, infections, isolated symptoms, deviant behaviors, and atypical variations of structure and functio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hip Dysplasia (human)
Hip dysplasia is an abnormality of the hip joint where the socket portion does not fully cover the ball portion, resulting in an increased risk for joint dislocation. Hip dysplasia may occur at birth or develop in early life. Regardless, it does not typically produce symptoms in babies less than a year old. Occasionally one leg may be shorter than the other. The left hip is more often affected than the right. Complications without treatment can include arthritis, limping, and low back pain. Females are affected more often than males. Risk factors for hip dysplasia include female sex, family history, certain swaddling practices, and breech presentation whether an infant is delivered vaginally or by cesarean section. If one identical twin is affected, there is a 40% risk the other will also be affected. Screening all babies for the condition by physical examination is recommended. Ultrasonography may also be useful. Many of those with mild instability resolve without specific ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Great Ormond Street Hospital
Great Ormond Street Hospital (informally GOSH, formerly the Hospital for Sick Children) is a children's hospital located in the Bloomsbury area of the London Borough of Camden, and a part of Great Ormond Street Hospital for Children NHS Foundation Trust. The hospital is the largest centre for child heart surgery in Britain and one of the largest centres for heart transplantation in the world. In 1962 it developed the first heart and lung bypass machine for children. With children's book author Roald Dahl, it developed an improved shunt valve for children with hydrocephalus, and non-invasive (percutaneous) heart valve replacements. Great Ormond Street performed the first UK clinical trials of the rubella vaccine, and the first bone marrow transplant and gene therapy for severe combined immunodeficiency.Breakthroughs The hospital is the largest centre for research and postgraduate teaching in children's health in Europe. In 1929, J. M. Barrie donated the copyright ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spanish Flu
The 1918–1920 flu pandemic, also known as the Great Influenza epidemic or by the common misnomer Spanish flu, was an exceptionally deadly global influenza pandemic caused by the H1N1 subtype of the influenza A virus. The earliest documented case was March 1918 in Kansas, United States, with further cases recorded in France, Germany and the United Kingdom in April. Two years later, nearly a third of the global population, or an estimated 500 million people, had been infected. Estimates of deaths range from 17 million to 50 million, and possibly as high as 100 million, making it the deadliest pandemic in history. The pandemic broke out near the end of World War I, when wartime censors in the belligerent countries suppressed bad news to maintain morale, but newspapers freely reported the outbreak in neutral Spain, creating a false impression of Spain as the epicenter and leading to the "Spanish flu" misnomer. Limited historical epidemiological data make the pandemic' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cologne
Cologne ( ; ; ) is the largest city of the States of Germany, German state of North Rhine-Westphalia and the List of cities in Germany by population, fourth-most populous city of Germany with nearly 1.1 million inhabitants in the city proper and over 3.1 million people in the Cologne Bonn Region, Cologne Bonn urban region. Cologne is also part of the Rhine-Ruhr metropolitan region, the List of EU metropolitan regions by GDP#2021 ranking of top four German metropolitan regions, second biggest metropolitan region by GDP in the European Union. Centered on the left bank of the Rhine, left (west) bank of the Rhine, Cologne is located on the River Rhine (Lower Rhine), about southeast of the North Rhine-Westphalia state capital Düsseldorf and northwest of Bonn, the former capital of West Germany. The city's medieval Cologne Cathedral () was the History of the world's tallest buildings#Churches and cathedrals: Tallest buildings between the 13th and 20th century, world's talles ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Knight Commander Of The Order Of St Michael And St George
The Most Distinguished Order of Saint Michael and Saint George is a British order of chivalry founded on 28 April 1818 by George, Prince of Wales (the future King George IV), while he was acting as prince regent for his father, King George III. It is named in honour of two military saints, Michael (archangel), Michael and Saint George, George. The Order of St Michael and St George was originally awarded to those holding commands or high position in the Mediterranean Sea, Mediterranean territories acquired in the Napoleonic Wars, and it was subsequently extended to holders of similar office or position in other territories of the British Empire. It is at present awarded to men and women who hold high office or who render extraordinary or important non-military service to the United Kingdom in a foreign country, and it can also be conferred for important or loyal service in relation to foreign and Commonwealth of Nations, Commonwealth affairs. Description The three classes of ap ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
First World War
World War I or the First World War (28 July 1914 – 11 November 1918), also known as the Great War, was a World war, global conflict between two coalitions: the Allies of World War I, Allies (or Entente) and the Central Powers. Fighting took place mainly in European theatre of World War I, Europe and the Middle Eastern theatre of World War I, Middle East, as well as in parts of African theatre of World War I, Africa and the Asian and Pacific theatre of World War I, Asia-Pacific, and in Europe was characterised by trench warfare; the widespread use of Artillery of World War I, artillery, machine guns, and Chemical weapons in World War I, chemical weapons (gas); and the introductions of Tanks in World War I, tanks and Aviation in World War I, aircraft. World War I was one of the List of wars by death toll, deadliest conflicts in history, resulting in an estimated World War I casualties, 10 million military dead and more than 20 million wounded, plus some 10 million civilian de ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dorothy Garrod
Dorothy Annie Elizabeth Garrod, CBE, FBA (5 May 1892 – 18 December 1968) was an English archaeologist who specialised in the Palaeolithic period. She held the position of Disney Professor of Archaeology at the University of Cambridge from 1939 to 1952, and was the first woman to hold a chair at either Oxford or Cambridge. Early life and education Garrod was the daughter of the physician Sir Archibald Garrod and Laura Elizabeth Smith, daughter of the surgeon Sir Thomas Smith, 1st Baronet. She was born in Chandos Street, London, and was educated at home. Her first teacher was Isabel Fry as governess. Garrod recalled Fry teaching her, at age nine, in Harley Street with the daughter of Walter Jessop. She later attended Birklands School in St Albans. Pamela Jane Smith writes of Garrod as follows: "Garrod was a solid member of Britain's intellectual aristocracy. Her father, Sir Archibald Garrod, had been Regius Professor of Medicine at Oxford and is regarded as the founder of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Royal College Of Physicians
The Royal College of Physicians of London, commonly referred to simply as the Royal College of Physicians (RCP), is a British professional membership body dedicated to improving the practice of medicine, chiefly through the accreditation of physicians by examination. Founded by royal charter from King Henry VIII in 1518, as the College of Physicians, the RCP is the oldest medical college in England. The RCP's home in Regent's Park is one of the few post-war buildings to be listed at Grade I. In 2016 it was announced that the RCP was to open new premises in Liverpool at The Spine, a new building in the Liverpool Knowledge Quarter. The Spine opened in May 2021. History The college was incorporated as "the President and College or Commonalty of the Faculty of Physic in London" when it received a royal charter in 1518, affirmed by Act of Parliament in 1523. It is not known when the name "Royal College of Physicians of London" was first assumed or granted. It came into use aft ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Master Of Arts (Oxbridge And Dublin)
In the universities of University of Oxford, Oxford, University of Cambridge, Cambridge, and University of Dublin, Dublin, Bachelor of Arts, Bachelors of Arts (BAs) are promoted to the rank of Master of Arts (MA), typically upon application after three or four years after graduation. No further examination or study is required for this promotion, which is a mark of seniority rather than an additional postgraduate qualification. According to the formula of ''ad eundem gradum'', the graduates of the Universities of Oxford, Cambridge, and Dublin are eligible to apply to incorporate and be granted equivalent academic degrees at any of the other two universities, provided that they wish to register for such a degree or are members of the academic staff; they also pay a required fee. The example of the "Steamboat ladies" (roughly 720 women graduates of both Oxford and Cambridge who received Dublin academic degrees) is one of the most popular incidents of incorporation. While not an earn ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
