|
5-methoxy-α-methyltryptamine
5-MeO-αMT, also known as 5-methoxy-α-methyltryptamine or as α,''O''-dimethylserotonin (α,''O''-DMS or Alpha-O), is a serotonergic psychedelic of the tryptamine, α-alkyltryptamine, and 5-methoxytryptamine families. It is a derivative of α-methyltryptamine (αMT) and an analogue of 5-MeO-DMT. The drug is said to be the most potent psychedelic of the simple indolealkylamines (i.e., tryptamines). It is active at oral doses of 2 to 4mg. Use The dosage range of 5-MeO-AMT listed in ''TiHKAL'' is 2.5 to 4.5mg and its duration is listed as 12 to 18hours. However, a wider recreational dosage range of 0.5 to 15mg has also been reported. 5-MeO-AMT has supposedly been sold as 4mg tablets by the street name Alpha-O and taken as a recreational drug. Since the DEA arrests of the makers of a huge percentage of the United States' LSD in 2000, 5-MeO-AMT may have occasionally been sold under the guise of LSD in liquid, sugar cube, or blotter form, though this may be due to DEA reports ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oral Administration
Oral administration is a route of administration whereby a substance is taken through the Human mouth, mouth, swallowed, and then processed via the digestive system. This is a common route of administration for many medications. Oral administration can be easier and less painful than other routes of administration, such as Injection (medicine), injection. However, the onset of action is relatively low, and the effectiveness is reduced if it is not absorbed properly in the digestive system, or if it is broken down by digestive enzymes before it can reach the bloodstream. Some medications may cause gastrointestinal side effects, such as nausea or vomiting, when taken orally. Oral administration can also only be applied to conscious patients, and patients able to swallow. Terminology ''Per os'' (; ''P.O.'') is an adverbial phrase meaning literally from Latin "through the mouth" or "by mouth". The expression is used in medicine to describe a treatment that is taken orally (but not ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
5-MeO-DMT
5-MeO-DMT (5-methoxy-''N'',''N''-dimethyltryptamine), also known as ''O''-methylbufotenin or mebufotenin (), is a naturally occurring psychedelic of the tryptamine family. It is found in a wide variety of plant species, and is also secreted by the glands of at least one toad species, the Colorado River toad. It may occur naturally in humans as well. Like its close relatives dimethyltryptamine (DMT) and bufotenin (5-HO-DMT), it has been used as an entheogen in South America. Slang terms include ''five-methoxy'', ''the power'', ''bufo'', and ''toad venom''. The drug has been described as the most powerful psychedelic and, by journalist Michael Pollan, as the "Mount Everest of psychedelics". Adverse effects of 5-MeO-DMT include sickness, vomiting, headache, chest pressure, fatigue, anxiety, fear, terror, confusion, paranoia, crying, loss of awareness and motor control, and reactivations. The drug acts as a non-selective serotonin receptor agonist, including of the sero ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Creative Thinking
Creativity is the ability to form novel and valuable ideas or works using one's imagination. Products of creativity may be intangible (e.g. an idea, scientific theory, literary work, musical composition, or joke), or a physical object (e.g. an invention, dish or meal, piece of jewelry, costume, a painting). Creativity may also describe the ability to find new solutions to problems, or new methods to accomplish a goal. Therefore, creativity enables people to solve problems in new ways. Most ancient cultures (including Ancient Greece, Ancient China, and Ancient India) lacked the concept of creativity, seeing art as a form of discovery rather than a form of creation. In the Judeo-Christian-Islamic tradition, creativity was seen as the sole province of God, and human creativity was considered an expression of God's work; the modern conception of creativity came about during the Renaissance, influenced by humanist ideas. Scholarly interest in creativity is found in a number o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Erowid
Erowid, also called Erowid Center, is a non-profit educational organization that provides information about psychoactive plants and chemicals. Erowid documents legal and illegal substances, including their intended and adverse effects. Information on Erowid's website is gathered from diverse sources including published literature, experts in related fields, and the experiences of the general public. Erowid acts as a publisher of new information as well as a library for the collection of documents and images published elsewhere. History Erowid was founded in April 1995 as a small business; their website appeared six months later. The name "Erowid" was chosen to reflect the organization's stated philosophy of education. Using Proto-Indo-European linguistic roots, "Erowid" roughly translates into "Earth Wisdom" ( *''h₁er-'', *''weyd-'').Emily Witt"The trip planners." '' New Yorker.'' 23 November 2015. Retrieved 2018-03-05. In 2005, the 501(c)(3) non-profit educational organ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blotting Paper
Blotting paper is a highly absorbent type of paper used to absorb ink or oil from writing material, particularly when quills or fountain pens were popular. It could also be used in testing how much oil is present in products. Blotting paper referred to as bibulous paper is mainly used in microscopy to remove excess liquids from the slide before viewing. Blotting paper has also been sold as a cosmetic to aid in the removal of skin oils and makeup. Manufacture Blotting paper is made from different materials of varying thickness, softness, etc. depending on the application. It is often made of cotton and manufactured on special paper machines. Blotting paper is reputed to be first referred to in the English language in the 15th century but there is a tradition in Norfolk, England that it was invented by accident at Lyng Mill on the River Wensum. It is reported that a Berkshire (England) paper mill worker failed to add sizing to a batch of paper that was being produced. The b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sugar Cube
Sugar cubes are white sugar granules pressed into small cubes measuring approximately 1 teaspoon each. They are usually used for sweetening drinks such as tea and coffee. They were invented in the early 19th century in response to the difficulties of breaking hard "sugarloafs" into small uniform size pieces. They are often found in cafes and restaurants, although their popularity as a DIY sweetener has waned with the rise of barista cafes. Nevertheless they still have many uses such as arts and crafts, as metaphor for the amount of sugar in a product, and at formal events. Size and packaging The typical size for each cube is between and , corresponding to the weight of approximately 3–5 grams, or approximately 1 teaspoon. However, the cube sizes and shapes vary greatly, for example, playing card suits-shaped pieces are produced under the name "bridge cube sugar". The typical retail packaging weight is 0.5 kilogram (1 pound (unit of weight), pound) or 1 kilogram / 2 pound ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lysergic Acid Diethylamide
Lysergic acid diethylamide, commonly known as LSD (from German ; often referred to as acid or lucy), is a Semisynthesis, semisynthetic, Hallucinogen, hallucinogenic compound derived from ergot, known for its powerful psychological effects and Serotonin, serotonergic activity. It was historically significant in psychiatry and 1960s counterculture; it is currently legally restricted but experiencing renewed scientific interest and increasing use. When taken orally, LSD has an onset of action within 0.4 to 1.0 hours (range: 0.1–1.8 hours) and a duration of effect lasting 7 to 12 hours (range: 4–22 hours). It is commonly administered via tabs of Blotting paper, blotter paper. LSD is extremely potent, with noticeable effects at doses as low as 20 Microgram, micrograms and is sometimes taken in much smaller amounts for microdosing. Yet no fatal human overdoses have been documented. LSD is mainly used recreationally or for spiritual purposes. LSD can cause mystical experiences. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
William Leonard Pickard
William Leonard Pickard (born October 21, 1945) is one of two people convicted in the largest lysergic acid diethylamide (LSD) manufacturing case in history. In 2000, while moving their LSD laboratory across Kansas, Pickard and Clyde Apperson were pulled over while driving a Ryder rental truck and a follow car. The laboratory had been stored near a renovated Atlas-E missile silo near Wamego, Kansas. Gordon Todd Skinner, one of the men intimately involved in the case but not charged due to his cooperation, owned the property where the laboratory equipment was stored. On July 27, 2020, Pickard was granted compassionate release from federal prison 20 years into his sentence. Background Prior to his arrest, Pickard was deputy director of the Drug Policy Research Program at the University of California, Los Angeles. He came from a well-to-do family; his father was a lawyer and his stepmother was a fungal disease expert at the Centers for Disease Control and Prevention. In high scho ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Recreational Drug
Recreational drug use is the use of one or more psychoactive drugs to induce an altered state of consciousness, either for pleasure or for some other casual purpose or pastime. When a psychoactive drug enters the user's body, it induces an Substance intoxication, intoxicating effect. Recreational drugs are commonly divided into three categories: depressants (drugs that induce a feeling of relaxation and calmness), stimulants (drugs that induce a sense of energy and alertness), and hallucinogens (drugs that induce perceptual distortions such as hallucination). In popular practice, recreational drug use is generally tolerated as a social behaviour, rather than perceived as the medical condition of self-medication. However, drug use and drug addiction are Social stigma, severely stigmatized everywhere in the world. Many people also use prescribed and controlled depressants such as opioids, opiates, and benzodiazepines. What controlled substances are considered generally unlawful t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Duration Of Action
Pharmacodynamics (PD) is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs). The effects can include those manifested within animals (including humans), microorganisms, or combinations of organisms (for example, infection). Pharmacodynamics and pharmacokinetics are the main branches of pharmacology, being itself a topic of biology interested in the study of the interactions of both endogenous and exogenous chemical substances with living organisms. In particular, pharmacodynamics is the study of how a drug affects an organism, whereas pharmacokinetics is the study of how the organism affects the drug. Both together influence dosing, benefit, and adverse effects. Pharmacodynamics is sometimes abbreviated as PD and pharmacokinetics as PK, especially in combined reference (for example, when speaking of PK/PD models). Pharmacodynamics places particular emphasis on dose–response relationships, that is, the relationships between drug con ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
TiHKAL
''TiHKAL: The Continuation'' is a 1997 book written by Alexander Shulgin and Ann Shulgin about a family of psychoactive drugs known as tryptamines. A sequel to '' PiHKAL: A Chemical Love Story'', ''TiHKAL'' is an acronym that stands for "Tryptamines I Have Known and Loved". Content ''TIHKAL'', much like its predecessor ''PIHKAL'', is divided into two parts. The first part, for which all rights are reserved, begins with a fictionalized autobiography, picking up where the similar section of ''PIHKAL'' left off; it then continues with a collection of essays on topics ranging from psychotherapy and the Jungian mind to the prevalence of DMT in nature, ayahuasca and the War on Drugs. The second part of ''TIHKAL'', which may be conditionally distributed for non-commercial reproduction , is a detailed synthesis manual for 55 psychedelic compounds (many discovered by Alexander Shulgin himself), including their chemical structures, dosage recommendations, and qualitative comments. Shul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
