1A-LSD
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1A-LSD
ALD-52, also known as 1-acetyl-LSD (1A-LSD), is a psychedelic drug of the substituted lysergamide, lysergamide family related to lysergic acid diethylamide (LSD). It has been reported to produce similar Psychoactive drug, psychoactive effects as LSD, but its pharmacological effects on humans are poorly understood. The drug is assumed to act as a prodrug to LSD in humans, and this has been substantiated ''in vitro''. ALD-52 was initially chemical synthesis, synthesized in 1957 by Albert Hofmann. The purported first confirmed detection of the substance on the illicit market occurred in April 2016. Use and effects In Entry 26 of his compendium ''TiHKAL'', which discussed LSD, chemist Alexander Shulgin touched briefly on the subject of ALD-52. His comments there are vague, second-hand accounts saying doses in the 50–175 μg range have resulted in various conclusions. One account found that there was less visual distortion than with LSD and it seemed to produce less anxiety an ...
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Serotonergic Psychedelic
Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary mental states (known as psychedelic experiences or "trips") and a perceived "expansion of consciousness". Also referred to as classic hallucinogens or serotonergic hallucinogens, the term ''psychedelic'' is sometimes used more broadly to include various other types of hallucinogens as well, such as those which are atypical or adjacent to psychedelia like salvia and MDMA, respectively. Classic psychedelics generally cause specific psychological, visual, and auditory changes, and oftentimes a substantially altered state of consciousness. They have had the largest influence on science and culture, and include mescaline, LSD, psilocybin, and DMT. There are a large number of both naturally occurring and synthetic serotonergic psychedelics. Most psychedelic drugs fall into one of the three families of chemical compounds: tryptamines, phenethylamines, or lysergamides. They pro ...
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Substituted Lysergamide
Lysergamides, also known as ergoamides or as lysergic acid amides, are amides of lysergic acid (LA). They are ergolines, with some lysergamides being found naturally in ergot as well as other fungi. Lysergamides are notable in containing embedded phenethylamine and tryptamine moieties within their ergoline ring system. The simplest lysergamides are ergine (lysergic acid amide; LSA) and isoergine (iso-lysergic acid amide; iso-LSA). In terms of pharmacology, the lysergamides include numerous serotonin and dopamine receptor agonists, most notably the psychedelic drug lysergic acid diethylamide (LSD) but also a number of pharmaceutical drugs like ergometrine, methylergometrine, methysergide, and cabergoline. Various analogues of LSD, such as the psychedelics ALD-52 (1A-LSD), ETH-LAD, LSZ, and 1P-LSD and the non-hallucinogenic 2-bromo-LSD (BOL-148), have also been developed. Ergopeptines like ergotamine, dihydroergotamine, and bromocriptine are also lysergamides, but with a ...
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Psychedelic Drug
Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary mental states (known as psychedelic experiences or "trips") and a perceived "expansion of consciousness". Also referred to as classic hallucinogens or serotonergic hallucinogens, the term ''psychedelic'' is sometimes used more broadly to include various other types of hallucinogens as well, such as those which are atypical or adjacent to psychedelia like salvia and MDMA, respectively. Classic psychedelics generally cause specific psychological, visual, and auditory changes, and oftentimes a substantially altered state of consciousness. They have had the largest influence on science and culture, and include mescaline, LSD, psilocybin, and DMT. There are a large number of both naturally occurring and synthetic serotonergic psychedelics. Most psychedelic drugs fall into one of the three families of chemical compounds: tryptamines, phenethylamines, or lysergamides. T ...
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Substituted Lysergamide
Lysergamides, also known as ergoamides or as lysergic acid amides, are amides of lysergic acid (LA). They are ergolines, with some lysergamides being found naturally in ergot as well as other fungi. Lysergamides are notable in containing embedded phenethylamine and tryptamine moieties within their ergoline ring system. The simplest lysergamides are ergine (lysergic acid amide; LSA) and isoergine (iso-lysergic acid amide; iso-LSA). In terms of pharmacology, the lysergamides include numerous serotonin and dopamine receptor agonists, most notably the psychedelic drug lysergic acid diethylamide (LSD) but also a number of pharmaceutical drugs like ergometrine, methylergometrine, methysergide, and cabergoline. Various analogues of LSD, such as the psychedelics ALD-52 (1A-LSD), ETH-LAD, LSZ, and 1P-LSD and the non-hallucinogenic 2-bromo-LSD (BOL-148), have also been developed. Ergopeptines like ergotamine, dihydroergotamine, and bromocriptine are also lysergamides, but with a ...
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Lysergic Acid Diethylamide
Lysergic acid diethylamide, commonly known as LSD (from German ; often referred to as acid or lucy), is a Semisynthesis, semisynthetic, Hallucinogen, hallucinogenic compound derived from ergot, known for its powerful psychological effects and Serotonin, serotonergic activity. It was historically significant in psychiatry and 1960s counterculture; it is currently legally restricted but experiencing renewed scientific interest and increasing use. When taken orally, LSD has an onset of action within 0.4 to 1.0 hours (range: 0.1–1.8 hours) and a duration of effect lasting 7 to 12 hours (range: 4–22 hours). It is commonly administered via tabs of Blotting paper, blotter paper. LSD is extremely potent, with noticeable effects at doses as low as 20 Microgram, micrograms and is sometimes taken in much smaller amounts for microdosing. Yet no fatal human overdoses have been documented. LSD is mainly used recreationally or for spiritual purposes. LSD can cause mystical experiences. ...
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Humphrey Osmond
Humphry Fortescue Osmond (1 July 1917 – 6 February 2004) was an English psychiatrist who moved to Canada and later the United States. He is known for inventing the word ''psychedelic'' and for his research into interesting and useful applications for psychedelic drugs. Osmond also explored aspects of the psychology of social environments, in particular how they influenced welfare or recovery in mental institutions. Biography Osmond was born in Surrey, England, and educated at Haileybury. As a young man, he worked for an architect and attended Guy's Hospital Medical School at King's College London. Following service as a surgeon-lieutenant in the Navy during World War II, Osmond trained to become a psychiatrist. Work with psychedelics After the war, Osmond joined the psychiatric unit at St George's Hospital, London, where he rose to become senior registrar. His time at the hospital proved pivotal in three respects: it was where he met his wife Amy "Jane" Roffey, who was wor ...
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Advisory Council On The Misuse Of Drugs
The Advisory Council on the Misuse of Drugs (ACMD) is a British statutory advisory non-departmental public body, which was established under the Misuse of Drugs Act 1971. Mandate Its terms of reference, according to the Act, are as follows: ''to keep under review the situation in the United Kingdom with respect to drugs which are being or appear to them likely to be misused and of which the misuse is having or appears to them capable of having harmful effects sufficient to constitute a social problem, and to give to any one or more of the Ministers, where either Council consider it expedient to do so or they are consulted by the Minister or Ministers in question, advice on measures (whether or not involving alteration of the law) which in the opinion of the Council ought to be taken for preventing the misuse of such drugs or dealing with social problems connected with their misuse, and in particular on measures which in the opinion of the Council, ought to be taken'' *a) ''fo ...
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UK Misuse Of Drugs Act
The Misuse of Drugs Act 1971 (c. 38) is an act of the Parliament of the United Kingdom. It represents action in line with treaty commitments under the Single Convention on Narcotic Drugs, the Convention on Psychotropic Substances, and the United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances. Offences under the act include: * Possession of a controlled drug unlawfully * Possession of a controlled drug with intent to supply it * Supplying or offering to supply a controlled drug (even where no charge is made for the drug) * Allowing premises you occupy or manage to be used unlawfully for the purpose of producing or supplying controlled drugs The act establishes the Home Secretary as the principal authority in a drug licensing system. Therefore, for example, various opiates are available legally as prescription-only medicines, and cannabis (hemp) may be grown under licence for 'industrial purposes'. The (SI 2001/3998), created under th ...
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Research Chemical
Research chemicals are chemical substances which scientists use for medical and scientific research purposes. One characteristic of a research chemical is that it is for laboratory research use only; a research chemical is not intended for human or veterinary use. In the United States, this distinction is required on the labels of research chemicals and exempts them from regulation under parts 100-740 in Title 21 of the Code of Federal Regulations ( 21CFR). Background Agricultural research chemicals Research agrochemicals are created and evaluated to select effective substances for commercial off-the-shelf end-user products. Many research agrochemicals are never publicly marketed. Agricultural research chemicals often use sequential code name A code name, codename, call sign, or cryptonym is a code word or name used, sometimes clandestinely, to refer to another name, word, project, or person. Code names are often used for military purposes, or in espionage. They may also be ...
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Oral Administration
Oral administration is a route of administration whereby a substance is taken through the Human mouth, mouth, swallowed, and then processed via the digestive system. This is a common route of administration for many medications. Oral administration can be easier and less painful than other routes of administration, such as Injection (medicine), injection. However, the onset of action is relatively low, and the effectiveness is reduced if it is not absorbed properly in the digestive system, or if it is broken down by digestive enzymes before it can reach the bloodstream. Some medications may cause gastrointestinal side effects, such as nausea or vomiting, when taken orally. Oral administration can also only be applied to conscious patients, and patients able to swallow. Terminology ''Per os'' (; ''P.O.'') is an adverbial phrase meaning literally from Latin "through the mouth" or "by mouth". The expression is used in medicine to describe a treatment that is taken orally (but not ...
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1cP-LSD
1cP-LSD (''N''1-(cyclopropylmethanoyl)-lysergic acid diethylamide) is an acylated derivative of lysergic acid diethylamide (LSD), which has been sold as a designer drug. It was first synthesized as a legal-LSD alternative by Lizard Labs, a Netherlands based research chemical laboratory. In tests on mice it was found to be an active psychedelic with similar potency to 1P-LSD. Legal status Public Health Agency of Sweden, Sweden's public health agency suggested classifying 1cP-LSD as a dangerous substance on 18 December 2019 and later classified it as such on 22 April 2021. See also * Lysergic acid diethylamide (LSD) * 1B-LSD * 1DD-LSD * 1P-LSD * 1V-LSD * ALD-52 * 1cP-AL-LAD * AL-LAD * ETH-LAD * 1P-ETH-LAD * PRO-LAD * LSM-775 * Lysergic acid 2,4-dimethylazetidide, LSZ * O-Acetylpsilocin (4-AcO-DMT) References

5-HT2A agonists Designer drugs Prodrugs Psychedelic lysergamides Serotonin receptor agonists {{hallucinogen-stub ...
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1B-LSD
1B-LSD (N1-butyryl-lysergic acid diethylamide) is an acylated derivative of lysergic acid diethylamide (LSD), which has been sold as a designer drug. In tests on mice it was found to be an active psychedelic, though with only around 1/7 the potency of LSD itself. Legal status 1B-LSD is illegal in Singapore. Sweden's public health agency suggested classifying 1B-LSD as a hazardous substance, on June 24, 2019. See also * Lysergic acid diethylamide (LSD) * 1cP-LSD * 1P-LSD * 1V-LSD * ALD-52 * 1cP-AL-LAD * AL-LAD * ETH-LAD * 1P-ETH-LAD * PRO-LAD * LSM-775 * LSZ * O-Acetylpsilocin 4-Acetoxy-''N'',''N''-dimethyltryptamine (4-AcO-DMT or 4-acetoxy-DMT), also known as ''O''-acetylpsilocin or psilacetin, is a psychedelic drug of the tryptamine family related to psilocybin and psilocin. It is a synthetic derivative of psiloci ... (4-AcO-DMT) References External links 1B-LSD - Isomer Design1B-LSD - PsychonautWikiThe Small & Handy 1-Bu-LSD Thread - BluelightWhat is 1B-LSD? ...
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