Vaporizer (inhalation device)
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A vaporizer or vaporiser, colloquially known as a vape, is a device used to vaporize substances for
inhalation Inhalation (or Inspiration) happens when air or other gases enter the lungs. Inhalation of air Inhalation of air, as part of the cycle of breathing, is a vital process for all human life. The process is autonomic (though there are exceptions ...
. Plant substances can be used, commonly
cannabis ''Cannabis'' () is a genus of flowering plants in the family Cannabaceae. The number of species within the genus is disputed. Three species may be recognized: '' Cannabis sativa'', '' C. indica'', and '' C. ruderalis''. Alternative ...
,
tobacco Tobacco is the common name of several plants in the genus '' Nicotiana'' of the family Solanaceae, and the general term for any product prepared from the cured leaves of these plants. More than 70 species of tobacco are known, but the ...
, or other herbs or blends of
essential oil An essential oil is a concentrated hydrophobic liquid containing volatile (easily evaporated at normal temperatures) chemical compounds from plants. Essential oils are also known as volatile oils, ethereal oils, aetheroleum, or simply as the o ...
. However, they can also be filled with a combination
propylene glycol Propylene glycol ( IUPAC name: propane-1,2-diol) is a viscous, colorless liquid, which is nearly odorless but possesses a faintly sweet taste. Its chemical formula is CH3CH(OH)CH2OH. Containing two alcohol groups, it is classed as a diol. It ...
,
glycerin Glycerol (), also called glycerine in British English and glycerin in American English, is a simple triol compound. It is a colorless, odorless, viscous liquid that is sweet-tasting and non-toxic. The glycerol backbone is found in lipids known ...
, and drugs such as
nicotine Nicotine is a naturally produced alkaloid in the nightshade family of plants (most predominantly in tobacco and '' Duboisia hopwoodii'') and is widely used recreationally as a stimulant and anxiolytic. As a pharmaceutical drug, it is use ...
(e.g. extract from tobacco) or
tetrahydrocannabinol Tetrahydrocannabinol (THC) is the principal psychoactive constituent of cannabis and one of at least 113 total cannabinoids identified on the plant. Although the chemical formula for THC (C21H30O2) describes multiple isomers, the term ''THC' ...
as a liquid solution. Vaporizers contain various forms of extraction chambers including straight bore, venturi, or sequential venturi, and are made of materials such as metal or glass. The extracted vapor may be collected in an inflatable bag, or inhaled directly through a hose or pipe. When used properly, cooler temperatures due to lack of combustion result in significantly more efficient extraction of the ingredients. Hence, the irritating and harmful effects of smoking are heavily reduced, as is its secondhand smoke.


Cannabis vaporizers

Cannabis flower is commonly consumed using a dry herb vaporizer. The cannabis may be heated in a chamber via indirect flame exposure or an electrical heating element, allowing users to inhale the resulting vapor. The temperatures reached are cooler than the combustion temperature of cannabis, which is around 230–315 °C (445–600 °F). Vaporizing is more efficient than
smoking Smoking is a practice in which a substance is burned and the resulting smoke is typically breathed in to be tasted and absorbed into the bloodstream. Most commonly, the substance used is the dried leaves of the tobacco plant, which have b ...
, because approximately 30% of
THC Tetrahydrocannabinol (THC) is the principal psychoactive constituent of cannabis and one of at least 113 total cannabinoids identified on the plant. Although the chemical formula for THC (C21H30O2) describes multiple isomers, the term ''THC' ...
in cannabis or hashish cigarettes is destroyed by
pyrolysis The pyrolysis (or devolatilization) process is the thermal decomposition of materials at elevated temperatures, often in an inert atmosphere. It involves a change of chemical composition. The word is coined from the Greek-derived elements '' ...
during smoking. Cannabis is also consumed via the vaporization of cannabis concentrates or oils that have been extracted from the plant, commonly referred to as "dabbing". Users typically employ a torch to heat a small cup shaped quartz or titanium attatchment on a bong before dabbing the oil onto the heated surface and inhaling the vapors through the bong. This route of consumption is generally much more potent than smoking or vaporizing marijuana flower due to the increased concentration of cannabinoids. Users typically report that the effects of dabbing are much more intense than regular cannabis, while also being shorter lived. Cannabis concentrate is also commonly used in e-cigarette style vaporizers known as "dab cartridges" or "THC pens". An e-cigarette is used to heat liquid cannabis oil, creating vapor that is inhaled by the user. The most frequently used Cannabis concentrate in e-cig vapes is THC distillate, although others frequently contain different forms of cannabis oil mixed with Polyethylene glycol or other additives to lower viscosity and create so called "THC e-liquid" for use in e-cigarettes. Natural and artificial terpenes are also frequently added by manufacturers to enhance flavor, often using blends that mimic popular cannabis strains or sugary foods such as candy or cereal. While vape pens deliver higher concentrations of THC to cannabis users, the psychoactive effects are reported to be shorter lasting than the effects of vaporizing or smoking traditional marijuana. File:Volcano Vaporizer.jpg, a Volcano vaporizer File:Aromatherapy 2.0.JPG, Vaporizer with water-cooling File:Vaporizer 01.JPG, A conduction-style vaporizer File:Vaporization-pipe-w-flame-filter2.png, A passive-convection "vaporization pipe" with flame filter File:Dabbing.JPG, A man inhaling cannabis concentrate vapor from a dab rig File:NYSDOH Announces Update on Investigation into Vaping-Associated Pulmonary Illnesses (48683410247).jpg, New York State Department of Health image showcasing a variety of THC vapes and packaging Of the studies that have investigated cannabis vaporization, few have addressed the quality of the vapor extracted and delivered; instead, studies usually focus on the mode of usage of the vaporizers. However, those that have addressed vapor quality have demonstrated promising results. Such studies suggest that the absence of combustion results in an aerosol that contains significantly lower amounts of harmful substances found in smoke, such as
tar Tar is a dark brown or black viscous liquid of hydrocarbons and free carbon, obtained from a wide variety of organic materials through destructive distillation. Tar can be produced from coal, wood, petroleum, or peat. "a dark brown or black bi ...
,
carbon monoxide Carbon monoxide ( chemical formula CO) is a colorless, poisonous, odorless, tasteless, flammable gas that is slightly less dense than air. Carbon monoxide consists of one carbon atom and one oxygen atom connected by a triple bond. It is the simpl ...
, and carcinogenic compounds known as polynuclear aromatic hydrocarbons (PAH). One study found that cannabis smoke contains 111 compounds (including several carcinogenic PAHs) in addition to the cannabinoids, whereas only 3 additional compounds were identified in cannabis vapor, other than the cannabinoids. This suggests that the vaporization of cannabis may be a safer alternative to combusted cannabis.


E-cigarette vaporizers

An electronic cigarette is a handheld
battery Battery most often refers to: * Electric battery, a device that provides electrical power * Battery (crime), a crime involving unlawful physical contact Battery may also refer to: Energy source *Automotive battery, a device to provide power t ...
-powered vaporizer that simulates
smoking Smoking is a practice in which a substance is burned and the resulting smoke is typically breathed in to be tasted and absorbed into the bloodstream. Most commonly, the substance used is the dried leaves of the tobacco plant, which have b ...
by providing some of the behavioral aspects of smoking, including the hand-to-mouth action of smoking, but without combusting tobacco. Using an e-cigarette is known as "vaping" and the user is referred to as a "vaper." Instead of
cigarette smoke Tobacco smoke is a sooty aerosol produced by the incomplete combustion of tobacco during the smoking of cigarettes and other tobacco products. Temperatures in burning cigarettes range from about 400 °C between puffs to about 900 °C ...
, the user inhales an
aerosol An aerosol is a suspension of fine solid particles or liquid droplets in air or another gas. Aerosols can be natural or anthropogenic. Examples of natural aerosols are fog or mist, dust, forest exudates, and geyser steam. Examples of anthropogen ...
, commonly called
vapor In physics, a vapor (American English) or vapour (British English and Canadian English; see spelling differences) is a substance in the gas phase at a temperature lower than its critical temperature,R. H. Petrucci, W. S. Harwood, and F. G. Her ...
. E-cigarettes typically have a
heating element A heating element converts electrical energy into heat through the process of Joule heating. Electric current through the element encounters resistance, resulting in heating of the element. Unlike the Peltier effect, this process is indepen ...
that atomizes a liquid solution called
e-liquid An electronic cigarette is a handheld battery-powered vaporizer that simulates smoking, but without tobacco combustion. E-cigarette components include a mouthpiece (drip tip), a cartridge (liquid storage area), a heating element/ atomizer, a mic ...
. E-cigarettes may be automatically activated by taking a puff; others turn on manually by pressing a button. Some e-cigarettes look like traditional cigarettes, but they come in many variations. Most versions are reusable, though some are disposable. There are first-generation, second-generation, third-generation, and fourth-generation devices. E-liquids usually contain
propylene glycol Propylene glycol ( IUPAC name: propane-1,2-diol) is a viscous, colorless liquid, which is nearly odorless but possesses a faintly sweet taste. Its chemical formula is CH3CH(OH)CH2OH. Containing two alcohol groups, it is classed as a diol. It ...
,
glycerin Glycerol (), also called glycerine in British English and glycerin in American English, is a simple triol compound. It is a colorless, odorless, viscous liquid that is sweet-tasting and non-toxic. The glycerol backbone is found in lipids known ...
,
nicotine Nicotine is a naturally produced alkaloid in the nightshade family of plants (most predominantly in tobacco and '' Duboisia hopwoodii'') and is widely used recreationally as a stimulant and anxiolytic. As a pharmaceutical drug, it is use ...
,
flavorings A flavoring (or flavouring), also known as flavor (or flavour) or flavorant, is a food additive used to improve the taste or smell of food. It changes the perceptual impression of food as determined primarily by the chemoreceptors of the gustato ...
, additives, and differing amounts of contaminants. E-liquids are also sold without propylene glycol, nicotine, or flavors. The benefits and the health risks of e-cigarettes are uncertain. There is tentative evidence they may help people quit smoking, although they have not been proven to be more effective than
smoking cessation Smoking cessation, usually called quitting smoking or stopping smoking, is the process of discontinuing tobacco smoking. Tobacco smoke contains nicotine, which is addictive and can cause dependence. As a result, nicotine withdrawal often m ...
medicine. There is concern with the possibility that non-smokers and children may start nicotine use with e-cigarettes at a rate higher than anticipated than if they were never created. Following the possibility of
nicotine addiction Nicotine is a natural product, naturally produced alkaloid in the nightshade family of plants (most predominantly in tobacco and ''Duboisia hopwoodii'') and is widely used recreational drug use, recreationally as a stimulant and anxiolytic. As ...
from e-cigarette use, there is concern children may start smoking cigarettes. Youth who use e-cigarettes are more likely to go on to smoke cigarettes. Their part in tobacco harm reduction is unclear, while another review found they appear to have the potential to lower tobacco-related death and disease. Regulated US
Food and Drug Administration The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food ...
nicotine replacement products Nicotine replacement therapy (NRT) is a medically approved way to treat people with tobacco use disorder by taking nicotine through means other than tobacco. It is used to help with quitting smoking or stopping chewing tobacco. It increases the ...
may be safer than e-cigarettes, but e-cigarettes are generally seen as safer than combusted
tobacco products Tobacco is the agricultural product of the leaves of plants in the genus ''Nicotiana'', commonly termed ''tobacco plants''. All species of ''Nicotiana'' contain the addictive drug nicotine—a psychostimulant alkaloid found in all parts of the ...
. It is estimated their safety risk to users is similar to that of
smokeless tobacco Smokeless tobacco is a tobacco product that is used by means other than smoking. Their use involves chewing, sniffing, or placing the product between gum and the cheek or lip. Smokeless tobacco products are produced in various forms, such as che ...
. The long-term effects of e-cigarette use are unknown. The risk from serious adverse events was reported in 2016 to be low. Less serious
adverse effect An adverse effect is an undesired harmful effect resulting from a medication or other intervention, such as surgery. An adverse effect may be termed a " side effect", when judged to be secondary to a main or therapeutic effect. The term compl ...
s include abdominal pain, headache, blurry vision, throat and mouth irritation, vomiting, nausea, and coughing. Nicotine itself is associated with some health harms. In 2019 and 2020, an outbreak of severe lung illness throughout the US has been linked to the use of contaminated black market THC vape cartridges.


Other drug

Vaporizers can be used to inhale other recreational drugs as well. A wide variety can be consumed this way, either dissolved in e-liquid or vaporized directly. The use of e-cigarettes to inhale the
psychedelic drug Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary states of consciousness (known as psychedelic experiences or "trips").Pollan, Michael (2018). ''How to Change Your Mind: What the New Science o ...
DMT ''N'',''N''-Dimethyltryptamine (DMT or ''N'',''N''-DMT, SPL026) is a substituted tryptamine that occurs in many plants and animals, including human beings, and which is both a derivative and a structural analog of tryptamine. It is used as a ...
has been reported.


Medical vaporizers

Studies have shown that vaporizing cannabis exposes the user to lower levels of harmful substances than smoking cannabis. These findings are important for it is estimated that 10–20% of patients with
chronic pain Chronic pain is classified as pain that lasts longer than three to six months. In medicine, the distinction between acute and chronic pain is sometimes determined by the amount of time since onset. Two commonly used markers are pain that continue ...
,
multiple sclerosis Multiple (cerebral) sclerosis (MS), also known as encephalomyelitis disseminata or disseminated sclerosis, is the most common demyelinating disease, in which the insulating covers of nerve cells in the brain and spinal cord are damaged. This ...
,
epilepsy Epilepsy is a group of non-communicable neurological disorders characterized by recurrent epileptic seizures. Epileptic seizures can vary from brief and nearly undetectable periods to long periods of vigorous shaking due to abnormal electrica ...
, and HIV/
AIDS Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual ma ...
have admitted to smoking cannabis for therapeutic purposes. For patients, a study found that smoking cannabis sativa reduced daily pain by 34%, a statistically significant amount. In a study published in the '' Journal of Psychopharmacology'' in May 2008, it was stated that vaporizers were a "suitable method for the administration of THC". A 2007 study by the
University of California, San Francisco The University of California, San Francisco (UCSF) is a public land-grant research university in San Francisco, California. It is part of the University of California system and is dedicated entirely to health science and life science. It ...
, published in the ''Journal of the American Academy of Neurology'', found that "there was virtually no exposure to harmful combustion products using the vaporizing device". A 2006 study performed by researchers at
Leiden University Leiden University (abbreviated as ''LEI''; nl, Universiteit Leiden) is a public research university in Leiden, Netherlands. The university was founded as a Protestant university in 1575 by William, Prince of Orange, as a reward to the city o ...
found that vaporizers were "safe and effective
cannabinoid Cannabinoids () are several structural classes of compounds found in the cannabis plant primarily and most animal organisms (although insects lack such receptors) or as synthetic compounds. The most notable cannabinoid is the phytocannabinoid tet ...
delivery system(s)". The study stated that the amount of THC delivered by vaporizers were equivalent to the amount delivered by smoking. Because of those studies and other studies, vaporizers are considered medically sound devices for delivering THC.


Efficiency

The proposed factors affecting output include: * Temperature * Specimen
density Density (volumetric mass density or specific mass) is the substance's mass per unit of volume. The symbol most often used for density is ''ρ'' (the lower case Greek letter rho), although the Latin letter ''D'' can also be used. Mathematicall ...
* Weight, content of water and
essential oil An essential oil is a concentrated hydrophobic liquid containing volatile (easily evaporated at normal temperatures) chemical compounds from plants. Essential oils are also known as volatile oils, ethereal oils, aetheroleum, or simply as the o ...
s * Consistency of material in the filling chamber * Storage time of the vapor * Inhalation method (breathing technique) Not all those have been scientifically tested. Research using vaporizers found the delivery efficiency highest at around , falling to about half efficiency at depending on material. The purest preparations produced the highest efficiencies, about 56% for pure THC versus 29% for plant material (female flower tops) with 12% THCA content. Besides THC, several other cannabinoids as well as a range of other plant components including terpenoids were detected in the plant material. Using pure THC in the vaporizer, no degradation products (delta-8-THC (D8-THC), cannabinol (CBN), or unknown compounds) were detected by
HPLC High-performance liquid chromatography (HPLC), formerly referred to as high-pressure liquid chromatography, is a technique in analytical chemistry used to separate, identify, and quantify each component in a mixture. It relies on pumps to p ...
analysis. The longer vapor is stored, the more THC is lost as it condenses on the surface of the vaporizer or the balloon. This loss may be negligible over a few minutes but may exceed 50% after 90 minutes. The Leiden University study found that as much as 30–40% of inhaled THC was not absorbed by the lungs but simply exhaled. However, they did not find large individual differences in the amounts exhaled.


Culinary application

Vaporizers are sometimes used by chefs as a method of applying controlled heat to herbs and spices to release flavors that are otherwise difficult to titrate or apply, or that might be spoiled by overheating during cooking. Grant Achatz, chef-proprietor of Alinea in Chicago, "uses the aroma-filled bags as place-mats, punctured when plates are placed in front of the customer".


See also

*
Anesthetic vaporizer An anesthetic vaporizer (American English) or anaesthetic vaporiser (British English) is a device generally attached to an anesthetic machine which delivers a given concentration of a volatile anesthetic agent. It works by controlling the vapo ...
*
Aromatherapy Aromatherapy is based on the usage of aromatic materials including essential oils and other aroma compounds, with claims for improving psychological and physical well-being. It is offered as a complementary therapy or as a form of alternative ...
* Chasing the dragon * Eagle Bill *
Nebulizer In medicine, a nebulizer (American English) or nebuliser (British English) is a drug delivery device used to administer medication in the form of a mist inhaled into the lungs. Nebulizers are commonly used for the treatment of asthma, cystic fibro ...


Bibliography

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References

{{Cannabis resources Cannabis smoking Dosage forms Drug delivery devices Drug paraphernalia Nicotine products with harm-reduction claims