This list contains a list of EC numbers for the first group, EC 1,

oxidoreductases In biochemistry, an oxidoreductase is an enzyme that catalyzes the transfer of electrons from one molecule, the reductant, also called the electron donor, to another, the oxidant, also called the electron acceptor. This group of enzymes usually uti ...

, placed in numerical order as determined by the Nomenclature Committee of the

International Union of Biochemistry and Molecular Biology The International Union of Biochemistry and Molecular Biology (IUBMB) is an international non-governmental organisation concerned with biochemistry and molecular biology. Formed in 1955 as the International Union of Biochemistry (IUB), the union ...

. All official information is tabulated at the website of the committee. The database is developed and maintained by Andrew McDonald.

EC 1.1 Acting on the CH-OH group of donors

EC 1.1.1 With Nicotinamide adenine dinucleotide or NADP as acceptor

alcohol dehydrogenase Alcohol dehydrogenases (ADH) () are a group of dehydrogenase enzymes that occur in many organisms and facilitate the interconversion between alcohols and aldehydes or ketones with the reduction of nicotinamide adenine dinucleotide (NAD+) to NA ...

*: alcohol dehydrogenase (NADP⁺) *:

homoserine dehydrogenase In enzymology, a homoserine dehydrogenase () is an enzyme that catalyzes the chemical reaction :L-homoserine + NAD(P)+ \rightleftharpoons L-aspartate 4-semialdehyde + NAD(P)H + H+ The 2 substrates of this enzyme are L-homoserine and NAD+ ...

*: (''R,R'')-butanediol dehydrogenase * EC 1.1.1.5: acetoin dehydrogenase. Now EC 1.1.1.303, diacetyl reductase ''R'')-acetoin formingand EC 1.1.1.304, diacetyl reductase ''S'')-acetoin forming*:

glycerol dehydrogenase Glycerol dehydrogenase (, also known as NAD+-linked glycerol dehydrogenase, glycerol: NAD+ 2-oxidoreductase, GDH, GlDH, GlyDH) is an enzyme in the oxidoreductase family that utilizes the NAD+ to catalyze the oxidation of glycerol to form glyceron ...

propanediol-phosphate dehydrogenase In enzymology, a propanediol-phosphate dehydrogenase () is an enzyme that catalyzes the chemical reaction :propane-1,2-diol 1-phosphate + NAD+ \rightleftharpoons hydroxyacetone phosphate + NADH + H+ Thus, the two substrates of this enzyme are ...

*: glycerol-3-phosphate dehydrogenase (NAD⁺) *: D-xylulose reductase *: L-xylulose reductase *: D-arabinitol 4-dehydrogenase *: L-arabinitol 4-dehydrogenase *: L-arabinitol 2-dehydrogenase *: L-iditol 2-dehydrogenase *: D-iditol 2-dehydrogenase *: galactitol 2-dehydrogenase *: mannitol-1-phosphate 5-dehydrogenase *: inositol 2-dehydrogenase *: glucuronate reductase *: glucuronolactone reductase *: (-)-menthol dehydrogenase *: (+)-neomenthol dehydrogenase *:

aldose reductase In enzymology, aldose reductase (or aldehyde reductase) () is a cytosolic NADPH-dependent oxidoreductase that catalyzes the reduction of a variety of aldehydes and carbonyls, including monosaccharides. It is primarily known for catalyzing the red ...

UDP-glucose 6-dehydrogenase UDP-glucose 6-dehydrogenase is a cytosolic enzyme that in humans is encoded by the ''UGDH'' gene. The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as ...

*: (R)-4-hydroxyphenyllactate dehydrogenase *: histidinol dehydrogenase, *: quinate/shikimate dehydrogenase (NAD⁺) *: shikimate dehydrogenase (NADP⁺) *: glyoxylate reductase *: L-lactate dehydrogenase *: D-lactate dehydrogenase *: glycerate dehydrogenase *:

3-hydroxybutyrate dehydrogenase In enzymology, 3-hydroxybutyrate dehydrogenase () is an enzyme that catalyzes the chemical reaction: : (''R'')-3-hydroxybutanoate + NAD+ \rightleftharpoons acetoacetate + NADH + H+ Thus, the two substrates of this enzyme are (''R'')-3-hydr ...

*: 3-hydroxyisobutyrate dehydrogenase *: mevaldate reductase *: mevaldate reductase (NADPH) *: hydroxymethylglutaryl-CoA reductase (NADPH) *: 3-hydroxyacyl-CoA dehydrogenase *: acetoacetyl-CoA reductase *:

malate dehydrogenase Malate dehydrogenase () (MDH) is an enzyme that reversibly catalyzes the oxidation of malate to oxaloacetate using the reduction of NAD+ to NADH. This reaction is part of many metabolic pathways, including the citric acid cycle. Other malate ...

*: malate dehydrogenase (oxaloacetate-decarboxylating) *:

malate dehydrogenase (decarboxylating) Malate dehydrogenase (decarboxylating) () or NAD-malic enzyme (NAD-ME) is an enzyme that catalyzes the chemical reaction :(S)-malate + NAD+ \rightleftharpoons pyruvate + CO2 + NADH Thus, the two substrates of this enzyme are (S)-malate and NA ...

*: malate dehydrogenase (oxaloacetate-decarboxylating) (NADP⁺) *: isocitrate dehydrogenase (NAD⁺) *: isocitrate dehydrogenase (NADP⁺) *: phosphogluconate 2-dehydrogenase *: phosphogluconate dehydrogenase (NADP⁺-dependent, decarboxylating) *: L-gulonate 3-dehydrogenase *: L-arabinose 1-dehydrogenase *: glucose 1-dehydrogenase AD(P)⁺)*: D-galactose 1-dehydrogenase *: glucose-6-phosphate dehydrogenase (NADP⁺) *: 3α-hydroxysteroid 3-dehydrogenase (''Si''-specific) *: 3(or 17)β-hydroxysteroid dehydrogenase *: 3α-hydroxycholanate dehydrogenase (NAD⁺) *: 3α(or 20β)-hydroxysteroid dehydrogenase *: allyl-alcohol dehydrogenase *: lactaldehyde reductase (NADPH) *: ribitol 2-dehydrogenase *: fructuronate reductase *: tagaturonate reductase *: 3-hydroxypropionate dehydrogenase *: 2-hydroxy-3-oxopropionate reductase *: 4-hydroxybutyrate dehydrogenase *: 17β-estradiol 17-dehydrogenase *EC 1.1.1.63: testosterone 17β-dehydrogenase. Now EC 1.1.1.239, 3α(17β)-hydroxysteroid dehydrogenase (NAD⁺) *: testosterone 17β-dehydrogenase (NADP⁺) *: pyridoxine 4-dehydrogenase *: ω-hydroxydecanoate dehydrogenase *: mannitol 2-dehydrogenase * EC 1.1.1.68: 5,10-methylenetetrahydrofolate reductase. Now EC 1.5.1.20, methylenetetrahydrofolate reductase AD(P)H*: gluconate 5-dehydrogenase * EC 1.1.1.70: D-glucuronolactone dehydrogenase. Now included with EC 1.2.1.3 aldehyde dehydrogenase (NAD⁺) *: alcohol dehydrogenase AD(P)⁺*: glycerol dehydrogenase (NADP⁺) *: octanol dehydrogenase * EC 1.1.1.74: D-aminopropanol dehydrogenase (reaction due to EC 1.1.1.4 (''R,R'')-butanediol dehydrogenase) *: (''R'')-aminopropanol dehydrogenase *: (''S,S'')-butanediol dehydrogenase *: lactaldehyde reductase *: methylglyoxal reductase (NADH-dependent) *: glyoxylate reductase (NADP⁺) *: isopropanol dehydrogenase (NADP⁺) *: hydroxypyruvate reductase *: malate dehydrogenase (NADP⁺) *: D-malate dehydrogenase (decarboxylating) *: dimethylmalate dehydrogenase *: 3-isopropylmalate dehydrogenase *: ketol-acid reductoisomerase (NADP⁺) *: homoisocitrate dehydrogenase *: hydroxymethylglutaryl-CoA reductase * EC 1.1.1.89: dihydroxyisovalerate dehydrogenase (isomerizing). Now included with EC 1.1.1.86 ketol-acid reductoisomerase *:

aryl-alcohol dehydrogenase In enzymology, an aryl-alcohol dehydrogenase () is an enzyme that catalyzes the chemical reaction :an aromatic alcohol + NAD+ \rightleftharpoons an aromatic aldehyde + NADH + H+ Thus, the two substrates of this enzyme are aromatic alcohol and ...

*: aryl-alcohol dehydrogenase (NADP⁺) *: oxaloglycolate reductase (decarboxylating) *: tartrate dehydrogenase *: glycerol-3-phosphate dehydrogenase AD(P)⁺*:

phosphoglycerate dehydrogenase Phosphoglycerate dehydrogenase (PHGDH) is an enzyme that catalyzes the chemical reactions :3-phospho-D-glycerate + NAD+ \rightleftharpoons 3-phosphonooxypyruvate + NADH + H+ :2-hydroxyglutarate + NAD+ \rightleftharpoons 2-oxoglutarate + NADH + ...

sorbitol-6-phosphate 2-dehydrogenase In enzymology, a sorbitol-6-phosphate dehydrogenase () is an enzyme that catalyzes the chemical reaction :D-sorbitol 6-phosphate + NAD+ \rightleftharpoons D-fructose 6-phosphate + NADH + H+ Thus, the two substrates of this enzyme are D-sorbi ...

*: 15-hydroxyprostaglandin dehydrogenase (NAD⁺) *: D-pinitol dehydrogenase *: sequoyitol dehydrogenase *: perillyl-alcohol dehydrogenase *: 3β-hydroxy-Δ5-steroid dehydrogenase *: 11β-hydroxysteroid dehydrogenase *: 16α-hydroxysteroid dehydrogenase *: estradiol 17α-dehydrogenase *: 20α-hydroxysteroid dehydrogenase *: 21-hydroxysteroid dehydrogenase (NAD⁺) *: 21-hydroxysteroid dehydrogenase (NADP⁺) *: 3α-hydroxy-5β-androstane-17-one 3α-dehydrogenase *: sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) *: ureidoglycolate dehydrogenase * EC 1.1.1.155: homoisocitrate dehydrogenase. The enzyme is identical to EC 1.1.1.87, homoisocitrate dehydrogenase *: glycerol 2-dehydrogenase (NADP⁺) *: 3-hydroxybutyryl-CoA dehydrogenase * EC 1.1.1.158: Now EC 1.3.1.98, UDP-''N''-acetylmuramate dehydrogenase *: 7α-hydroxysteroid dehydrogenase *: dihydrobunolol dehydrogenase * EC 1.1.1.161: The activity is part of EC 1.14.13.15, cholestanetriol 26-monooxygenase *: erythrulose reductase *: cyclopentanol dehydrogenase *: hexadecanol dehydrogenase *: 2-alkyn-1-ol dehydrogenase *: hydroxycyclohexanecarboxylate dehydrogenase *: hydroxymalonate dehydrogenase *: 2-dehydropantolactone reductase (''Re''-specific) *: 2-dehydropantoate 2-reductase *: 3β-hydroxysteroid-4α-carboxylate 3-dehydrogenase (decarboxylating) * EC 1.1.1.171: Now EC 1.5.1.20, methylenetetrahydrofolate reductase AD(P)H*: 2-oxoadipate reductase *: L-rhamnose 1-dehydrogenase *:

cyclohexane-1,2-diol dehydrogenase In enzymology, a cyclohexane-1,2-diol dehydrogenase () is an enzyme that catalyzes the chemical reaction :trans-cyclohexane-1,2-diol + NAD+ \rightleftharpoons 2-hydroxycyclohexan-1-one + NADH + H+ Thus, the two substrates of this enzyme are t ...

*: D-xylose 1-dehydrogenase *: 12α-hydroxysteroid dehydrogenase *: glycerol-3-phosphate 1-dehydrogenase (NADP⁺) *: 3-hydroxy-2-methylbutyryl-CoA dehydrogenase *: D-xylose 1-dehydrogenase (NADP⁺, D-xylono-1,5-lactone-forming) * EC 1.1.1.180: Now included with EC 1.1.1.131 mannuronate reductase *: cholest-5-ene-3β,7α-diol 3β-dehydrogenase * EC 1.1.1.182: Now included with EC 1.1.1.198 (+)-borneol dehydrogenase, EC 1.1.1.227 (-)-borneol dehydrogenase and EC 1.1.1.228 (+)-sabinol dehydrogenase *: geraniol dehydrogenase (NADP⁺) *: carbonyl reductase (NADPH) *: L-glycol dehydrogenase *: dTDP-galactose 6-dehydrogenase *: GDP-4-dehydro-D-rhamnose reductase *: prostaglandin-F synthase *: prostaglandin-E2 9-reductase *:

indole-3-acetaldehyde reductase (NADH) In enzymology, an indole-3-acetaldehyde reductase (NADH) () is an enzyme that catalyzes the chemical reaction :(indol-3-yl)ethanol + NAD+ \rightleftharpoons (indol-3-yl)acetaldehyde + NADH + H+ Thus, the two substrates of this enzyme are (in ...

indole-3-acetaldehyde reductase (NADPH) In enzymology, an indole-3-acetaldehyde reductase (NADPH) () is an enzyme that catalyzes the chemical reaction :(indol-3-yl)ethanol + NADP+ \rightleftharpoons (indol-3-yl)acetaldehyde + NADPH + H+ Thus, the two substrates of this enzyme are ( ...

*: long-chain-alcohol dehydrogenase *: 5-amino-6-(5-phosphoribosylamino)uracil reductase *: coniferyl-alcohol dehydrogenase *:

cinnamyl-alcohol dehydrogenase In enzymology, a cinnamyl-alcohol dehydrogenase () is an enzyme that catalyzes the chemical reaction :cinnamyl alcohol + NADP+ \rightleftharpoons cinnamaldehyde + NADPH + H+ Thus, the two substrates of this enzyme are cinnamyl alcohol and NAD ...

eugenol synthase Eugenol synthase (, ''LtCES1'', ''EGS1'', ''EGS2'') is an enzyme with systematic name ''eugenol:NADP+ oxidoreductase (coniferyl ester reducing)''. This enzyme catalyses the following chemical reaction: eugenol + a carboxylate In organic chemi ...

isoeugenol synthase Isoeugenol synthase (, ''IGS1'', ''t-anol/isoeugenol synthase 1'') is an enzyme with systematic name ''eugenol:NADP+ oxidoreductase (coniferyl acetate reducing)''. This enzyme catalyses the following chemical reaction. : isoeugenol Isoeugenol ...

*: benzil reductase ''S'')-benzoin forming*: benzil reductase ''R'')-benzoin forming*: (–)-''endo''-fenchol dehydrogenase *: (+)-thujan-3-ol dehydrogenase *: 8-hydroxygeraniol dehydrogenase *: sepiapterin reductase (L-''threo''-7,8-dihydrobiopterin forming) *: zerumbone synthase *: 5-exo-hydroxycamphor dehydrogenase *: nicotine blue oxidoreductase *: 2-deoxy-''scyllo''-inosamine dehydrogenase *: very-long-chain 3-oxoacyl-CoA reductase *: secoisolariciresinol dehydrogenase *: chanoclavine-I dehydrogenase *: decaprenylphospho-β-D-''erythro''-pentofuranosid-2-ulose 2-reductase *: methylecgonone reductase *: UDP-''N''-acetyl-2-amino-2-deoxyglucuronate dehydrogenase *: UDP-''N''-acetyl-D-mannosamine dehydrogenase *: L-2-hydroxycarboxylate dehydrogenase (NAD⁺) *: (2''R'')-3-sulfolactate dehydrogenase (NADP⁺) *: dTDP-6-deoxy-L-talose 4-dehydrogenase (NAD⁺) *: 1-deoxy-11β-hydroxypentalenate dehydrogenase *: CDP-abequose synthase *: CDP-paratose synthase : At present (October 2021) most of the entries from 343 onwards have no Wikipedia articles * EC 1.1.1.343: phosphogluconate dehydrogenase (NAD⁺-dependent, decarboxylating) * EC 1.1.1.344: dTDP-6-deoxy-L-talose 4-dehydrogenase AD(P)⁺* EC 1.1.1.345: D-2-hydroxyacid dehydrogenase (NAD⁺) * EC 1.1.1.346: 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) * EC 1.1.1.347: geraniol dehydrogenase (NAD⁺) * EC 1.1.1.348: (3''R'')-2′-hydroxyisoflavanone reductase * EC 1.1.1.349: norsolorinic acid ketoreductase * EC 1.1.1.350: ureidoglycolate dehydrogenase (NAD⁺) * EC 1.1.1.351: phosphogluconate dehydrogenase AD(P)⁺-dependent, decarboxylating* EC 1.1.1.352: 5′-hydroxyaverantin dehydrogenase * EC 1.1.1.353: versiconal hemiacetal acetate reductase * EC 1.1.1.354: farnesol dehydrogenase (NAD⁺) * EC 1.1.1.355: 2′-dehydrokanamycin reductase * EC 1.1.1.356: GDP-L-colitose synthase * EC 1.1.1.357: 3α-hydroxysteroid 3-dehydrogenase * EC 1.1.1.358: 2-dehydropantolactone reductase * EC 1.1.1.359: aldose 1-dehydrogenase AD(P)⁺* EC 1.1.1.360: glucose/galactose 1-dehydrogenase * EC 1.1.1.361: glucose-6-phosphate 3-dehydrogenase * EC 1.1.1.362: aklaviketone reductase * EC 1.1.1.363: glucose-6-phosphate dehydrogenase AD(P)⁺* EC 1.1.1.364: dTDP-4-dehydro-6-deoxy-α-D-gulose 4-ketoreductase * EC 1.1.1.365: D-galacturonate reductase * EC 1.1.1.366: L-idonate 5-dehydrogenase (NAD⁺) * EC 1.1.1.367: UDP-2-acetamido-2,6-β-L-arabino-hexul-4-ose reductase * EC 1.1.1.368: 6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase * EC 1.1.1.369: D-chiro-inositol 1-dehydrogenase * EC 1.1.1.370: ''scyllo''-inositol 2-dehydrogenase (NAD⁺) * EC 1.1.1.371: ''scyllo''-inositol 2-dehydrogenase (NADP⁺) * EC 1.1.1.372: D/L-glyceraldehyde reductase * EC 1.1.1.373: sulfolactaldehyde 3-reductase * EC 1.1.1.374: UDP-''N''-acetylglucosamine 3-dehydrogenase * EC 1.1.1.375: L-2-hydroxycarboxylate dehydrogenase AD(P)⁺* EC 1.1.1.376: L-arabinose 1-dehydrogenase AD(P)⁺* EC 1.1.1.377: L-rhamnose 1-dehydrogenase (NADP⁺) * EC 1.1.1.378: L-rhamnose 1-dehydrogenase AD(P)⁺* EC 1.1.1.379: (''R'')-mandelate dehydrogenase * EC 1.1.1.380: L-gulonate 5-dehydrogenase * EC 1.1.1.381: 3-hydroxy acid dehydrogenase * EC 1.1.1.382: ketol-acid reductoisomerase (NAD⁺) * EC 1.1.1.383: ketol-acid reductoisomerase AD(P)⁺* EC 1.1.1.384: dTDP-3,4-didehydro-2,6-dideoxy-α-D-glucose 3-reductase * EC 1.1.1.385: dihydroanticapsin dehydrogenase * EC 1.1.1.386: ipsdienol dehydrogenase * EC 1.1.1.387: L-serine 3-dehydrogenase (NAD⁺) * EC 1.1.1.388: glucose-6-phosphate dehydrogenase (NAD⁺) * EC 1.1.1.389: 2-dehydro-3-deoxy-L-galactonate 5-dehydrogenase * EC 1.1.1.390: sulfoquinovose 1-dehydrogenase * EC 1.1.1.391: 3β-hydroxycholanate 3-dehydrogenase (NAD⁺) * EC 1.1.1.392: 3α-hydroxycholanate dehydrogenase (NADP⁺) * EC 1.1.1.393: 3β-hydroxycholanate 3-dehydrogenase (NADP⁺) * EC 1.1.1.394: aurachin B dehydrogenase * EC 1.1.1.395: 3α-hydroxy bile acid-CoA-ester 3-dehydrogenase * EC 1.1.1.396: bacteriochlorophyllide a dehydrogenase * EC 1.1.1.397: β-methylindole-3-pyruvate reductase * EC 1.1.1.398: 2-glutathionyl-2-methylbut-3-en-1-ol dehydrogenase * EC 1.1.1.399: 2-oxoglutarate reductase * EC 1.1.1.400: 2-methyl-1,2-propanediol dehydrogenase * EC 1.1.1.401: 2-dehydro-3-deoxy-L-rhamnonate dehydrogenase (NAD⁺) * EC 1.1.1.402: D-erythritol 1-phosphate dehydrogenase * EC 1.1.1.403: D-threitol dehydrogenase (NAD⁺) * EC 1.1.1.404: tetrachlorobenzoquinone reductase * EC 1.1.1.405: ribitol-5-phosphate 2-dehydrogenase (NADP⁺) * EC 1.1.1.406: galactitol 2-dehydrogenase (L-tagatose-forming) * EC 1.1.1.407: D-altritol 5-dehydrogenase * EC 1.1.1.408: 4-phospho-D-threonate 3-dehydrogenase * EC 1.1.1.409: 4-phospho-D-erythronate 3-dehydrogenase * EC 1.1.1.410: D-erythronate 2-dehydrogenase * EC 1.1.1.411: L-threonate 2-dehydrogenase * EC 1.1.1.412: 2-alkyl-3-oxoalkanoate reductase * EC 1.1.1.413: A-factor type γ-butyrolactone 1′-reductase (1''S''-forming) * EC 1.1.1.414: L-galactonate 5-dehydrogenase * EC 1.1.1.415: noscapine synthase * EC 1.1.1.416: isopyridoxal dehydrogenase (5-pyridoxolactone-forming) * EC 1.1.1.417: 3β-hydroxysteroid-4β-carboxylate 3-dehydrogenase (decarboxylating) * EC 1.1.1.418: plant 3β-hydroxysteroid-4α-carboxylate 3-dehydrogenase (decarboxylating) * EC 1.1.1.419: nepetalactol dehydrogenase * EC 1.1.1.420: D-apiose dehydrogenase * EC 1.1.1.421: D-apionate oxidoisomerase * EC 1.1.1.422: pseudoephedrine dehydrogenase * EC 1.1.1.423: (1''R'',2''S'')-ephedrine 1-dehydrogenase * EC 1.1.1.424: D-xylose 1-dehydrogenase (NADP⁺, D-xylono-1,4-lactone-forming) * EC 1.1.1.425: levoglucosan dehydrogenase * EC 1.1.1.426: UDP-''N''-acetyl-α-D-quinovosamine dehydrogenase

EC 1.1.2 With a cytochrome as acceptor

*EC 1.1.2.1: glycerolphosphate dehydrogenase. As the acceptor is now known, the enzyme has been transferred to EC 1.1.5.3, glycerol-3-phosphate dehydrogenase. *: mannitol dehydrogenase (cytochrome) *: L-lactate dehydrogenase (cytochrome) *: D-lactate dehydrogenase (cytochrome) *: D-lactate dehydrogenase (cytochrome c-553) *: polyvinyl alcohol dehydrogenase (cytochrome) *: methanol dehydrogenase (cytochrome c) *: alcohol dehydrogenase (cytochrome c) *EC 1.1.2.9: 1-butanol dehydrogenase (cytochrome c) * *EC 1.1.2.10: lanthanide-dependent methanol dehydrogenase * : *No Wikipedia article

EC 1.1.3 With oxygen as acceptor

* EC 1.1.3.1: Now included with EC 1.1.3.15 (''S'')-2-hydroxy-acid oxidase * : L-lactate oxidase * * : malate oxidase * :

glucose oxidase The glucose oxidase enzyme (GOx or GOD) also known as notatin (EC number 1.1.3.4) is an oxidoreductase that catalyses the oxidation of glucose to hydrogen peroxide and D-glucono-δ-lactone. This enzyme is produced by certain species of fungi and ...

* : hexose oxidase * : cholesterol oxidase * : aryl-alcohol oxidase * : L-gulonolactone oxidase * : galactose oxidase * : pyranose oxidase * : L-sorbose oxidase * : pyridoxine 4-oxidase * : alcohol oxidase * : catechol oxidase (dimerizing) * : (''S'')-2-hydroxy-acid oxidase * : ecdysone oxidase * : choline oxidase * : Secondary-alcohol oxidase * : 4-hydroxymandelate oxidase * : long-chain-alcohol oxidase * : glycerol-3-phosphate oxidase * EC 1.1.3.22: Now EC 1.17.3.2, xanthine oxidase. The enzyme was incorrectly classified as acting on a CH-OH group * :

Thiamine oxidase In enzymology, a thiamine oxidase () is an enzyme that catalyzes the chemical reaction ::thiamine + 2 O2 + H2O \rightleftharpoons thiamine acetic acid + 2 H2O2 The 3 substrates of this enzyme are thiamine, O2, and H2O, whereas its two produc ...

* : L-galactonolactone oxidase * EC 1.1.3.25: Now included with EC 1.1.99.18, cellobiose dehydrogenase (acceptor) * EC 1.1.3.26: Now EC 1.21.3.2, columbamine oxidase * : hydroxyphytanate oxidase * : nucleoside oxidase * : N-acylhexosamine oxidase * : polyvinyl-alcohol oxidase * EC 1.1.3.31: deleted, cannot be distinguished from EC 1.1.3.13, alcohol oxidase * EC 1.1.3.32: Now EC 1.14.21.1, (''S'')-stylopine synthase * EC 1.1.3.33: Now EC 1.14.21.2, (''S'')-cheilanthifoline synthase * EC 1.1.3.34: Now EC 1.14.21.3, berbamunine synthase * EC 1.1.3.35: Now EC 1.14.21.4, salutaridine synthase * EC 1.1.3.36: Now EC 1.14.21.5, (''S'')-canadine synthase * : D-arabinono-1,4-lactone oxidase * : vanillyl-alcohol oxidase * : nucleoside oxidase (H₂O₂-forming) * : D-mannitol oxidase * : xylitol oxidase * : prosolanapyrone-II oxidase * : paromamine 6′-oxidase * : 6′′′-hydroxyneomycin C oxidase * EC 1.1.3.45: aclacinomycin-N oxidase * * EC 1.1.3.46: 4-hydroxymandelate oxidase * * EC 1.1.3.47: 5-(hydroxymethyl)furfural oxidase * * EC 1.1.3.48: 3-deoxy-α-D-''manno''-octulosonate 8-oxidase * * EC 1.1.3.49: (''R'')-mandelonitrile oxidase * : *No Wikipedia article

EC 1.1.4 With a disulfide as acceptor

* EC 1.1.4.1: Now EC 1.17.4.4, vitamin-K-epoxide reductase (warfarin-sensitive) * EC 1.1.4.2: Now EC 1.17.4.5, vitamin-K-epoxide reductase (warfarin-insensitive)

EC 1.1.5 With a quinone or similar compound as acceptor

* EC 1.1.5.1: deleted, see EC 1.1.99.18 cellobiose dehydrogenase (acceptor) * : quinoprotein glucose dehydrogenase * : glycerol-3-phosphate dehydrogenase (quinone) * : malate dehydrogenase (quinone) * : alcohol dehydrogenase (quinone) * : formate dehydrogenase-N * : cyclic alcohol dehydrogenase (quinone) * : quinate dehydrogenase (quinone)

EC 1.1.9 With a copper protein as acceptor

* : alcohol dehydrogenase (azurin)

EC 1.1.98 With other, known, acceptors

* EC 1.1.98.1: Now EC 1.1.9.1, alcohol dehydrogenase (azurin) * : glucose-6-phosphate dehydrogenase (coenzyme-F₄₂₀) * : decaprenylphospho-β-D-ribofuranose 2-oxidase * EC 1.1.98.3: decaprenylphospho-β-D-ribofuranose 2-dehydrogenase * * EC 1.1.98.4: F₄₂₀H₂:quinone oxidoreductase * * EC 1.1.98.5: secondary-alcohol dehydrogenase (coenzyme-F₄₂₀) * * EC 1.1.98.6: ribonucleoside-triphosphate reductase (formate) * * EC 1.1.98.7: serine-type anaerobic sulfatase-maturating enzyme * : *No Wikipedia article

EC 1.1.99 With unknown physiological acceptors

* :

choline dehydrogenase In enzymology, a choline dehydrogenase () is an enzyme that catalyzes the chemical reaction :choline + acceptor \rightleftharpoons betaine aldehyde + reduced acceptor Thus, the two substrates of this enzyme are choline and acceptor, whereas i ...

* : L-2-hydroxyglutarate dehydrogenase * : gluconate 2-dehydrogenase (acceptor) * : dehydrogluconate dehydrogenase * EC 1.1.99.5: now EC 1.1.5.3, glycerol-3-phosphate dehydrogenase * : D-2-hydroxy-acid dehydrogenase * :

lactate—malate transhydrogenase In enzymology, a lactate—malate transhydrogenase () is an enzyme that catalyzes the chemical reaction :(S)-lactate + oxaloacetate \rightleftharpoons pyruvate + malate Thus, the two substrates of this enzyme are (S)-lactate and oxaloacetate, ...

* EC 1.1.99.8: Now EC 1.1.2.7, methanol dehydrogenase (cytochrome ''c'') and EC 1.1.2.8, alcohol dehydrogenase (cytochrome ''c''). * : pyridoxine 5-dehydrogenase * EC 1.1.99.10: Now EC 1.1.5.9, glucose 1-dehydrogenase (FAD, quinone) * EC 1.1.99.11: Now classified as EC 1.1.5.14, fructose 5-dehydrogenase * : sorbose dehydrogenase * : glucoside 3-dehydrogenase * :

glycolate dehydrogenase In enzymology, a glycolate dehydrogenase () is an enzyme that catalyzes the chemical reaction :glycolate + acceptor \rightleftharpoons glyoxylate + reduced acceptor Thus, the two substrates of this enzyme are glycolate and acceptor, whereas i ...

* EC 1.1.99.15: Now EC 1.5.1.20, methylenetetrahydrofolate reductase AD(P)H* EC 1.1.99.16: Now EC EC 1.1.5.4, malate dehydrogenase (quinone) * EC 1.1.99.17: Now EC 1.1.5.2, quinoprotein glucose dehydrogenase * : cellobiose dehydrogenase (acceptor) * EC 1.1.99.19: Now EC 1.17.99.4, uracil/thymine dehydrogenase * : alkan-1-ol dehydrogenase (acceptor) * : D-sorbitol dehydrogenase (acceptor) * :

glycerol dehydrogenase (acceptor) In enzymology, a glycerol dehydrogenase (acceptor) () is an enzyme that catalyzes the chemical reaction :glycerol + acceptor \rightleftharpoons glycerone + reduced acceptor Thus, the two substrates of this enzyme are glycerol and acceptor, w ...

* EC 1.1.99.23: Now EC 1.1.2.6, polyvinyl alcohol dehydrogenase (cytochrome) * :

hydroxyacid-oxoacid transhydrogenase In enzymology, a hydroxyacid-oxoacid transhydrogenase () is an enzyme that catalyzes the chemical reaction :(S)-3-hydroxybutanoate + 2-oxoglutarate \rightleftharpoons acetoacetate + (R)-2-hydroxyglutarate Thus, the two substrates of this enzym ...

* EC 1.1.99.25: Now EC 1.1.5.8, quinate dehydrogenase (quinone), * : 3-hydroxycyclohexanone dehydrogenase * : (''R'')-pantolactone dehydrogenase (flavin) * : glucose-fructose oxidoreductase * : pyranose dehydrogenase (acceptor) * : 2-oxoacid reductase * : (''S'')-mandelate dehydrogenase * : L-sorbose 1-dehydrogenase * EC 1.1.99.33: Now EC 1.17.99.7, formate dehydrogenase (acceptor) * EC 1.1.99.34: now EC 1.1.98.2, glucose-6-phosphate dehydrogenase (coenzyme-F₄₂₀) * : soluble quinoprotein glucose dehydrogenase * : alcohol dehydrogenase (nicotinoprotein) * : methanol dehydrogenase (nicotinoprotein) * : 2-deoxy-''scyllo''-inosamine dehydrogenase (AdoMet-dependent) * : D-2-hydroxyglutarate dehydrogenase * EC 1.1.99.40: (''R'')-2-hydroxyglutarate—pyruvate transhydrogenase * * EC 1.1.99.41: 3-hydroxy-1,2-didehydro-2,3-dihydrotabersonine reductase * * EC 1.1.99.42: 4-pyridoxic acid dehydrogenase * : *No Wikipedia article

EC 1.2 Acting on the aldehyde or oxo group of donors

EC 1.2.1 With NAD⁺ or NADP⁺ as acceptor

* EC 1.2.1.1: deleted, replaced by EC 1.1.1.284, ''S''-(hydroxymethyl)glutathione dehydrogenase and EC 4.4.1.22, ''S''-(hydroxymethyl)glutathione synthase * EC 1.2.1.2: Now EC 1.17.1.9, formate dehydrogenase * : aldehyde dehydrogenase (NAD⁺) * : aldehyde dehydrogenase (NADP⁺) * : aldehyde dehydrogenase (NAD(P)⁺) * EC 1.2.1.6: deleted (was benzaldehyde dehydrogenase) * : benzaldehyde dehydrogenase (NADP⁺) * :

betaine-aldehyde dehydrogenase In enzymology, a betaine-aldehyde dehydrogenase () is an enzyme that catalyzes the chemical reaction :betaine aldehyde + NAD+ + H2O \rightleftharpoons betaine + NADH + 2 H+ The 3 substrates of this enzyme are betaine aldehyde, NAD+, and H2O, ...

* : glyceraldehyde-3-phosphate dehydrogenase (NADP⁺) * : acetaldehyde dehydrogenase (acetylating) * :

aspartate-semialdehyde dehydrogenase In enzymology, an aspartate-semialdehyde dehydrogenase () is an enzyme that is very important in the biosynthesis of amino acids in prokaryotes, fungi, and some higher plants. It forms an early branch point in the metabolic pathway forming lysine, ...

* :

glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) In enzymology, a glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) () is an enzyme that catalyzes the chemical reaction :D-glyceraldehyde 3-phosphate + phosphate + NAD+ \rightleftharpoons 3-phospho-D-glyceroyl phosphate + NADH + H+ The ...

phenylacetaldehyde dehydrogenase In enzymology, a phenylacetaldehyde dehydrogenase () is an enzyme that catalyzes the chemical reaction :phenylacetaldehyde + NAD+ + H2O \rightleftharpoons phenylacetate + NADH + 2 H+ The 3 substrates of this enzyme are phenylacetaldehyde, NA ...

* EC 1.2.1.40: part of EC 1.14.13.15, cholestanetriol 26-monooxygenase * :

glutamate-5-semialdehyde dehydrogenase In enzymology, a glutamate-5-semialdehyde dehydrogenase () is an enzyme that catalyzes the chemical reaction :L-glutamate 5-semialdehyde + phosphate + NADP+ \rightleftharpoons L-glutamyl 5-phosphate + NADPH + H+ The 3 substrates of this enzyme ...

* : hexadecanal dehydrogenase (acylating) * EC 1.2.1.43: Now EC 1.17.1.10, formate dehydrogenase (NADP⁺) * :

cinnamoyl-CoA reductase Cinnamoyl-CoA reductase (), systematically named cinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating) but commonly referred to by the acronym CCR, is an enzyme that catalyzes the reduction of a substituted cinnamoyl-CoA to its corresponding ...

* EC 1.2.1.45: Now EC 1.1.1.312, 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase * :

formaldehyde dehydrogenase In enzymology, a formaldehyde dehydrogenase () is an enzyme that catalyzes the chemical reaction :formaldehyde + NAD+ + H2O \rightleftharpoons formate + NADH + H+ The 3 substrates of this enzyme are formaldehyde, NAD+, and H2O, whereas its 3 ...

glutamyl-tRNA reductase A glutamyl-tRNA reductase () is an enzyme that catalyzes the chemical reaction :L-glutamate 1-semialdehyde + NADP+ + tRNAGlu \rightleftharpoons L-glutamyl-tRNAGlu + NADPH + H+ The 3 substrates of this enzyme are L-glutamate 1-semialdehyde, NA ...

* : succinylglutamate-semialdehyde dehydrogenase * :

erythrose-4-phosphate dehydrogenase In enzymology, an erythrose-4-phosphate dehydrogenase () is an enzyme that catalyzes the chemical reaction :D-erythrose 4-phosphate + NAD+ + H2O \rightleftharpoons 4-phosphoerythronate + NADH + 2 H+ The 3 substrates of this enzyme are D-eryt ...

* : sulfoacetaldehyde dehydrogenase * : abieta-7,13-dien-18-al dehydrogenase * : malonyl CoA reductase (malonate semialdehyde-forming) * : succinate-semialdehyde dehydrogenase (acylating) * : 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP⁺) * : 2-formylbenzoate dehydrogenase * : succinate-semialdehyde dehydrogenase (NADP⁺) * : long-chain acyl- cyl-carrier-proteinreductase * : sulfoacetaldehyde dehydrogenase (acylating) * : β-apo-4′-carotenal oxygenase * : 3-succinoylsemialdehyde-pyridine dehydrogenase * : alcohol-forming fatty acyl-CoA reductase * : 2-hydroxymuconate-6-semialdehyde dehydrogenase * : geranial dehydrogenase * EC 1.2.1.87: propanal dehydrogenase (CoA-propanoylating) * * EC 1.2.1.88: L-glutamate γ-semialdehyde dehydrogenase * * EC 1.2.1.89: D-glyceraldehyde dehydrogenase (NADP⁺) * * EC 1.2.1.90: glyceraldehyde-3-phosphate dehydrogenase AD(P)⁺* * EC 1.2.1.91: 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase * * EC 1.2.1.92: 3,6-anhydro-α-L-galactose dehydrogenase * * EC 1.2.1.93: formate dehydrogenase (NAD+, ferredoxin). Now EC 1.17.1.11, formate dehydrogenase (NAD⁺, ferredoxin) * * EC 1.2.1.94: farnesal dehydrogenase * * EC 1.2.1.95: L-2-aminoadipate reductase * * EC 1.2.1.96: 4-hydroxybenzaldehyde dehydrogenase (⁺+) * * EC 1.2.1.97: 3-sulfolactaldehyde dehydrogenase * * EC 1.2.1.98: 2-hydroxy-2-methylpropanal dehydrogenase * * EC 1.2.1.99: 4-(γ-glutamylamino)butanal dehydrogenase * * EC 1.2.1.100: 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase * * EC 1.2.1.101: L-tyrosine reductase * * EC 1.2.1.102: isopyridoxal dehydrogenase (5-pyridoxate-forming) * * EC 1.2.1.103: mino-group carrier protein6-phospho-L-2-aminoadipate reductase * * EC 1.2.1.104: pyruvate dehydrogenase system * * EC 1.2.1.105: 2-oxoglutarate dehydrogenase system * * EC 1.2.1.106: mino-group carrier protein5-phospho-L-glutamate reductase * * EC 1.2.1.107: glyceraldehyde-3-phosphate dehydrogenase (arsenate-transferring) * : * No Wikipedia article

EC 1.2.2 With a cytochrome as acceptor

* : formate dehydrogenase (cytochrome) * EC 1.2.2.2: Now covered by EC 1.2.5.1, pyruvate dehydrogenase (quinone) * EC 1.2.2.3: Now EC 1.17.2.3, formate dehydrogenase (cytochrome-''c''-553) * EC 1.2.2.4: Now classified as EC 1.2.5.3, aerobic carbon monoxide dehydrogenase

EC 1.2.3 With oxygen as acceptor

* :

aldehyde oxidase Aldehyde oxidase (AO) is a metabolizing enzyme, located in the cytosolic compartment of tissues in many organisms. AO catalyzes the oxidation of aldehydes into carboxylic acid, and in addition, catalyzes the hydroxylation of some heterocycles. ...

* EC 1.2.3.2: Now EC 1.17.3.2, xanthine oxidase * : pyruvate oxidase * :

oxalate oxidase In enzymology, an oxalate oxidase () is an oxalate degrading enzyme that catalyzes the chemical reaction: :oxalate + O2 + 2 H+ \rightleftharpoons 2 CO2 + H2O2 The 3 substrates of this enzyme are oxalate, O2, and H+, whereas its two products a ...

* : glyoxylate oxidase * : pyruvate oxidase (CoA-acetylating) * : indole-3-acetaldehyde oxidase * : pyridoxal oxidase * : aryl-aldehyde oxidase * EC 1.2.3.10: deleted, activity due to EC 1.2.2.4 carbon-monoxide dehydrogenase (cytochrome ''b''-561) * EC 1.2.3.11: retinal oxidase * EC 1.2.3.12: Now included with EC 1.2.3.1, aldehyde oxidase * EC 1.2.3.13: Now EC 1.14.13.82, vanillate monooxygenase * : Abscisic-aldehyde oxidase * EC 1.2.3.15: (methyl)glyoxal oxidase * : * No Wikipedia article

EC 1.2.4 With a disulfide as acceptor

* : pyruvate dehydrogenase (acetyl-transferring) * : oxoglutarate dehydrogenase (succinyl-transferring) * EC 1.2.4.3: Now included with EC 1.2.4.4, 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) * : 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)

EC 1.2.5 With a quinone or similar compound as acceptor

* : pyruvate dehydrogenase (quinone) * EC 1.2.5.2: aldehyde dehydrogenase (quinone) * * EC 1.2.5.3: aerobic carbon monoxide dehydrogenase * : *No Wikipedia article

EC 1.2.7 With an iron–sulfur protein as acceptor

* :

pyruvate synthase In enzymology, a pyruvate synthase () is an enzyme that catalyzes the interconversion of pyruvate and acetyl-CoA. It is also called pyruvate:ferredoxin oxidoreductase (PFOR). The relevant equilibrium catalysed by PFOR is: :pyruvate + CoA + oxid ...

* EC 1.2.7.2: Now included with EC 1.2.7.1, pyruvate synthase. * : 2-oxoglutarate synthase * : anaerobic carbon monoxide dehydrogenase * :

aldehyde ferredoxin oxidoreductase In enzymology, an aldehyde ferredoxin oxidoreductase () is an enzyme that catalyzes the chemical reaction :an aldehyde + H2O + 2 oxidized ferredoxin an acid + 2 H+ + 2 reduced ferredoxin This enzyme belongs to the family of oxidoreductases, ...

* :

glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) In enzymology, a glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) () is an enzyme that catalyzes the chemical reaction :D-glyceraldehyde-3-phosphate + H2O + 2 oxidized ferredoxin \rightleftharpoons 3-phospho-D-glycerate + 2 H+ + 2 reduced f ...

* : 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) * : indolepyruvate ferredoxin oxidoreductase * EC 1.2.7.9: deleted, identical to EC 1.2.7.3, 2-oxoglutarate synthase * : oxalate oxidoreductase * EC 1.2.7.11: 2-oxoacid oxidoreductase (ferredoxin) * * EC 1.2.7.12: formylmethanofuran dehydrogenase * : *No Wikipedia article

EC 1.2.99: With unknown physiological acceptors

* EC 1.2.99.1: Now EC 1.17.99.4, uracil/thymine dehydrogenase * EC 1.2.99.2: Now EC 1.2.7.4, carbon-monoxide dehydrogenase (ferredoxin) * EC 1.2.99.3: Now EC 1.2.5.2, aldehyde dehydrogenase (quinone) * EC 1.2.99.4: Now EC 1.2.98.1, formaldehyde dismutase * EC 1.2.99.5: Now EC 1.2.7.12, formylmethanofuran dehydrogenase * : carboxylate reductase * : aldehyde dehydrogenase (FAD-independent) * EC 1.2.99.8: glyceraldehyde dehydrogenase (FAD-containing) * * EC 1.2.99.9: Now EC 1.17.98.3, formate dehydrogenase (coenzyme F₄₂₀) * EC 1.2.99.10: 4,4′-diapolycopenoate synthase * : *No Wikipedia article

EC 1.3 Acting on the CH-CH group of donors

EC 1.3.1 With NAD⁺ or NADP⁺ as acceptor

* : dihydrouracil dehydrogenase (NAD⁺) * : dihydropyrimidine dehydrogenase (NADP⁺) * : Δ⁴-3-oxosteroid 5β-reductase * EC 1.3.1.4: transferred to EC 1.3.1.22, 3-oxo-5α-steroid 4-dehydrogenase (NADP⁺) * : cucurbitacin Δ²³-reductase * :

fumarate reductase (NADH) In enzymology, a fumarate reductase (NADH) () is an enzyme that catalyzes the chemical reaction :succinate + NAD+ \rightleftharpoons fumarate + NADH + H+ Thus, the two substrates of this enzyme are succinate and NAD+, whereas its three product ...

* : ''meso''-tartrate dehydrogenase * : acyl-CoA dehydrogenase (NADP⁺) * : enoyl- cyl-carrier-proteinreductase (NADH) * : enoyl- cyl-carrier-proteinreductase (NADPH, ''Si''-specific) * : 2-coumarate reductase * : prephenate dehydrogenase * : prephenate dehydrogenase (NADP⁺) * : dihydroorotate dehydrogenase (NAD⁺) * : dihydroorotate dehydrogenase (NADP⁺) * : β-nitroacrylate reductase * : 3-methyleneoxindole reductase * : kynurenate-7,8-dihydrodiol dehydrogenase * : ''cis''-1,2-dihydrobenzene-1,2-diol dehydrogenase * : ''trans''-1,2-dihydrobenzene-1,2-diol dehydrogenase * : 7-dehydrocholesterol reductase * : 3-oxo-5α-steroid 4-dehydrogenase (NADP⁺) * EC 1.3.1.23: identical to EC 1.3.1.3, Δ4-3-oxosteroid 5β-reductase * :

biliverdin reductase Biliverdin reductase (BVR) is an enzyme () found in all tissues under normal conditions, but especially in reticulo-macrophages of the liver and spleen. BVR facilitates the conversion of biliverdin to bilirubin via the reduction of a double-b ...

* : 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase * EC 1.3.1.26: Now EC 1.17.1.8, 4-hydroxy-tetrahydrodipicolinate reductase * : 2-hexadecenal reductase * : 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase * : ''cis''-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase * EC 1.3.1.30: transferred to EC 1.3.1.22, 3-oxo-5α-steroid 4-dehydrogenase (NADP⁺) * : 2-enoate reductase * :

maleylacetate reductase In enzymology, a maleylacetate reductase () is an enzyme that catalyzes the chemical reaction :3-oxoadipate + NAD(P)+ \rightleftharpoons 2-maleylacetate + NAD(P)H + H+ The 3 substrates of this enzyme are 3-oxoadipate, NAD+, and NADP+, where ...

* :

protochlorophyllide reductase In enzymology, protochlorophyllide reductases (POR) are enzymes that catalyze the conversion from protochlorophyllide to chlorophyllide ''a''. They are oxidoreductases participating in the biosynthetic pathway to chlorophylls. There are t ...

* : 2,4-dienoyl-CoA reductase (NADPH), 2,4-dienoyl-CoA reductase 2''E'')-enoyl-CoA-producing* EC 1.3.1.35: Now EC 1.14.19.22, microsomal oleoyl-lipid 12-desaturase * : geissoschizine dehydrogenase * : ''cis''-2-enoyl-CoA reductase (NADPH) * : trans-2-enoyl-CoA reductase (NADPH) * : ''trans''-2-enoyl-CoA reductase (NADPH) * : 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase * : xanthommatin reductase * : 12-oxophytodienoate reductase * : arogenate dehydrogenase * : ''trans''-2-enoyl-CoA reductase (NAD⁺) * : 2′-hydroxyisoflavone reductase * :

biochanin-A reductase In enzymology, a biochanin-A reductase () is an enzyme that catalyzes the chemical reaction :dihydrobiochanin A + NADP+ \rightleftharpoons biochanin A + NADPH + H+ Thus, the two substrates of this enzyme are dihydrobiochanin A and NADP+, wh ...

* : α-santonin 1,2-reductase * : 13,14-dehydro-15-oxoprostaglandin 13-reductase * : ''cis''-3,4-dihydrophenanthrene-3,4-diol dehydrogenase * EC 1.3.1.50: n Now EC 1.1.1.252 tetrahydroxynaphthalene reductase * : 2′-hydroxydaidzein reductase * EC 1.3.1.52: Now EC 1.3.8.5, 2-methyl-branched-chain-enoyl-CoA reductase * : (3''S'',4''R'')-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase * :

precorrin-6A reductase In enzymology, a precorrin-6A reductase () is an enzyme that catalysis, catalyzes the chemical reaction ::precorrin-6A + Nicotinamide adenine dinucleotide phosphate, NADPH + H+ \rightleftharpoons precorrin-6B + NADP+ The three substrate (biochem ...

* EC 1.3.1.55: identical to EC 1.3.1.25, 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase * : ''cis''-2,3-dihydrobiphenyl-2,3-diol dehydrogenase * : phloroglucinol reductase * : 2,3-dihydroxy-2,3-dihydro-''p''-cumate dehydrogenase * EC 1.3.1.59: There is no evidence that the enzyme exists * : dibenzothiophene dihydrodiol dehydrogenase * EC 1.3.1.61: identical to EC 1.3.1.53, (3''S'',4''R'')-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase * : pimeloyl-CoA dehydrogenase * EC 1.3.1.63: Now EC 1.21.1.2, 2,4-dichlorobenzoyl-CoA reductase * : phthalate 4,5-''cis''-dihydrodiol dehydrogenase * : 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase * : ''cis''-dihydroethylcatechol dehydrogenase * : ''cis''-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase * : 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase * : zeatin reductase * : Δ¹⁴-sterol reductase * : Δ^24(24¹)-sterol reductase * : Δ²⁴-sterol reductase * : 1,2-dihydrovomilenine reductase * : 2-alkenal reductase AD(P)⁺* : 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH) * :

precorrin-2 dehydrogenase In enzymology, a precorrin-2 dehydrogenase () is an enzyme that catalyzes the chemical reaction :precorrin-2 + NAD+ \rightleftharpoons sirohydrochlorin + NADH + H+ The two substrates of this enzyme are precorrin-2 and NAD+; its three product ...

* : anthocyanidin reductase 2''R'',3''R'')-flavan-3-ol-forming* : arogenate dehydrogenase (NADP⁺) * : arogenate dehydrogenase (NAD(P)⁺) * EC 1.3.1.80: Now classified as EC 1.3.7.12, red chlorophyll catabolite reductase * : (+)-pulegone reductase * : (-)-isopiperitenone reductase * : geranylgeranyl diphosphate reductase * : acrylyl-CoA reductase (NADPH) * :

crotonyl-CoA carboxylase/reductase Crotonyl-CoA carboxylase/reductase (, ''CCR'', ''crotonyl-CoA reductase (carboxylating)'') is an enzyme with systematic name ''(2S)-ethylmalonyl-CoA:NADP+ oxidoreductase (decarboxylating)''. This enzyme catalyses the following chemical reaction ...

* : crotonyl-CoA reductase * : 3-(''cis''-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate dehydrogenase * : tRNA-dihydrouridine^16/17 synthase (NAD(P)⁺) * : tRNA-dihydrouridine⁴⁷ synthase (NAD(P)⁺) * : tRNA-dihydrouridine^20a/20b synthase (NAD(P)⁺) * : tRNA-dihydrouridine²⁰ synthase (NAD(P)⁺) * : artemisinic aldehyde Δ¹¹⁽¹³⁾-reductase * : very-long-chain enoyl-CoA reductase * : polyprenol reductase * : acrylyl-CoA reductase (NADH) * : ''Botryococcus'' squalene synthase * : botryococcene synthase * EC 1.3.1.98: Now known to be catalyzed by two different enzymes, EC 1.3.1.122, (''S'')-8-oxocitronellyl enol synthase, and EC 5.5.1.34, (+)-''cis,trans''-nepetalactol synthase * EC 1.3.1.100: chanoclavine-I aldehyde reductase * * EC 1.3.1.101: 2,3-bis-O-geranylgeranyl-''sn''-glycerol 1-phosphate reductase AD(P)H* * EC 1.3.1.102: 2-alkenal reductase (NADP+) * * EC 1.3.1.103: 2-haloacrylate reductase * * EC 1.3.1.104: enoyl- cyl-carrier-proteinreductase (NADPH) * * EC 1.3.1.105: 2-methylene-furan-3-one reductase * * EC 1.3.1.106: cobalt-precorrin-6A reductase * * EC 1.3.1.107: sanguinarine reductase * * EC 1.3.1.108: caffeoyl-CoA reductase * * EC 1.3.1.109: butanoyl-CoA dehydrogenase complex (NAD⁺, ferredoxin) * * EC 1.3.1.110: lactate dehydrogenase (NAD⁺,ferredoxin) * * EC 1.3.1.111: geranylgeranyl-bacteriochlorophyllide ''a'' reductase * * EC 1.3.1.112: anthocyanidin reductase 2''S'')-flavan-3-ol-forming* * EC 1.3.1.113: (4-alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl phosphate reductase * * EC 1.3.1.114: 3-dehydro-bile acid Δ^4,6-reductase * * EC 1.3.1.115: 3-oxocholoyl-CoA 4-desaturase * * EC 1.3.1.116: 7β-hydroxy-3-oxochol-24-oyl-CoA 4-desaturase * * EC 1.3.1.117: hydroxycinnamoyl-CoA reductase * * EC 1.3.1.118: meromycolic acid enoyl- cyl-carrier-proteinreductase * * EC 1.3.1.119: chlorobenzene dihydrodiol dehydrogenase * * EC 1.3.1.120: cyclohexane-1-carbonyl-CoA reductase NADP⁺) * * EC 1.3.1.121: 4-amino-4-deoxyprephenate dehydrogenase * * EC 1.3.1.122: (''S'')-8-oxocitronellyl enol synthase * * EC 1.3.1.123: 8-oxogeranial reductase * * EC 1.3.1.124: 2,4-dienoyl-CoA reductase 3''E'')-enoyl-CoA-producing* : *No Wikipedia article

EC 1.3.2 With a cytochrome as acceptor

* : now EC 1.3.99.2 * : now EC 1.3.99.3 * : galactonolactone dehydrogenase

EC 1.3.3 With oxygen as acceptor

* : dihydroorotate oxidase * : lathosterol oxidase * : coproporphyrinogen oxidase * :

protoporphyrinogen oxidase Protoporphyrinogen oxidase or protox is an enzyme that in humans is encoded by the ''PPOX'' gene. Protoporphyrinogen oxidase is responsible for the seventh step in biosynthesis of protoporphyrin IX. This porphyrin is the precursor to hemoglobin, ...

* : bilirubin oxidase * : acyl-CoA oxidase * : dihydrouracil oxidase * : tetrahydroberberine oxidase * : secologanin synthase * : tryptophan a,b-oxidase * : pyrroloquinoline-quinone synthase * : l-galactonolactone oxidase

EC 1.3.5 With a quinone or related compound as acceptor

* : succinate dehydrogenase (quinone) * : dihydroorotate dehydrogenase (quinone) * : protoporphyrinogen IX dehydrogenase (menaquinone) * :

fumarate reductase (quinol) Fumarate reductase (quinol) (, ''QFR,'' ''FRD'', ''menaquinol-fumarate oxidoreductase, quinol:fumarate reductase'') is an enzyme with systematic name ''succinate:quinone oxidoreductase''. This enzyme catalyzes the following chemical reaction: ...

* :

15-cis-phytoene desaturase 15-''cis''-phytoene desaturases (''PDS'', ''plant-type phytoene desaturases'') (, ''15-cis-phytoene:plastoquinone oxidoreductase''), are enzymes involved in the carotenoid biosynthesis in plants and cyanobacteria. Phytoene desaturases are membrane- ...

* : 9,9'-dicis-zeta-carotene desaturase

EC 1.3.7 With an iron–sulfur protein as acceptor

* : 6-hydroxynicotinate reductase * : 15,16-dihydrobiliverdin:ferredoxin oxidoreductase * : phycoerythrobilin:ferredoxin oxidoreductase * : phytochromobilin:ferredoxin oxidoreductase * : phycocyanobilin:ferredoxin oxidoreductase * : phycoerythrobilin synthase * : ferredoxin:protochlorophyllide reductase (ATP-dependent) * :

benzoyl-CoA reductase In enzymology, a benzoyl-CoA reductase () is an enzyme that catalyzes the chemical reaction :benzoyl-CoA + reduced acceptor + 2 ATP + 2 H2O \rightleftharpoons cyclohexa-1,5-diene-1-carbonyl-CoA + acceptor + 2 ADP + 2 phosphate The 4 substrates ...

* :

4-hydroxybenzoyl-CoA reductase In enzymology, a 4-hydroxybenzoyl-CoA reductase () is an enzyme found in some bacteria and archaea that catalyzes the chemical reaction :benzoyl-CoA + acceptor + H2O \rightleftharpoons 4-hydroxybenzoyl-CoA + reduced acceptor The 3 substrates of ...

* : pentalenolactone synthase * : chlorophyllide ''a'' reductase

EC 1.3.8 With a flavin as acceptor

* : short-chain acyl-CoA dehydrogenase * : 4,4′-diapophytoene desaturase (4,4′-diapolycopene-forming) * : (''R'')-benzylsuccinyl-CoA dehydrogenase * : isovaleryl-CoA dehydrogenase * : 2-methyl-branched-chain-enoyl-CoA reductase * : glutaryl-CoA dehydrogenase (ETF) * :

medium-chain acyl-CoA dehydrogenase Medium-chain acyl-CoA dehydrogenase (, ''fatty acyl coenzyme A dehydrogenase (ambiguous)'', ''acyl coenzyme A dehydrogenase (ambiguous)'', ''acyl dehydrogenase (ambiguous)'', ''fatty-acyl-CoA dehydrogenase (ambiguous)'', ''acyl CoA dehydrogenase (a ...

* : long-chain acyl-CoA dehydrogenase * : very-long-chain acyl-CoA dehydrogenase * EC 1.3.8.10: cyclohex-1-ene-1-carbonyl-CoA dehydrogenase * * EC 1.3.8.11: cyclohexane-1-carbonyl-CoA dehydrogenase (electron-transfer flavoprotein) * * EC 1.3.8.12: (2''S'')-methylsuccinyl-CoA dehydrogenase * * EC 1.3.8.13: crotonobetainyl-CoA reductase * * EC 1.3.8.14: L-prolyl- eptidyl-carrier proteindehydrogenase * * EC 1.3.8.15: 3-(aryl)acrylate reductase * * EC 1.3.8.16: 2-amino-4-deoxychorismate dehydrogenase * * EC 1.3.8.17: dehydro coenzyme F₄₂₀ reductase * : *No Wikipedia article

EC 1.3.98 With FMN acceptor

* : dihydroorotate dehydrogenase (fumarate) * EC 1.3.98.2: Now EC 1.3.4.1, fumarate reductase (CoM/CoB) * EC 1.3.98.3: coproporphyrinogen dehydrogenase * * EC 1.3.98.4: 5a,11a-dehydrotetracycline reductase * * EC 1.3.98.5: hydrogen peroxide-dependent heme synthase * * EC 1.3.98.6: AdoMet-dependent heme synthase * * EC 1.3.98.7: ycofactocin precursor peptidetyrosine decarboxylase : *No Wikipedia article

EC 1.3.99 With unknown physiological acceptors

* EC 1.3.99.1: The activity is included in EC 1.3.5.1, succinate dehydrogenase (quinone) * EC 1.3.99.2: Now EC 1.3.8.1, butyryl-CoA dehydrogenase. * EC 1.3.99.3: now EC 1.3.8.7, medium-chain acyl-CoA dehydrogenase, EC 1.3.8.8, long-chain acyl-CoA dehydrogenase and EC 1.3.8.9, very-long-chain acyl-CoA dehydrogenase * : 3-oxosteroid 1-dehydrogenase * : 3-oxo-5α-steroid 4-dehydrogenase (acceptor) * : 3-oxo-5β-steroid 4-dehydrogenase * EC 1.3.99.7: Now EC 1.3.8.6, glutaryl-CoA dehydrogenase * : 2-furoyl-CoA dehydrogenase * EC 1.3.99.9: Now EC 1.21.99.1, β-cyclopiazonate dehydrogenase * EC 1.3.99.10: Now EC 1.3.8.4, isovaleryl-CoA dehydrogenase * EC 1.3.99.11: transferred to EC 1.3.5.2, dihydroorotate dehydrogenase * EC 1.3.99.12: Now classified as EC 1.3.8.5, 2-methyl-branched-chain-enoyl-CoA reductase * : Now EC 1.3.8.8, long-chain-acyl-CoA dehydrogenase * : cyclohexanone dehydrogenase * EC 1.3.99.15: Now EC 1.3.7.8 * : isoquinoline 1-oxidoreductase * : quinoline 2-oxidoreductase * : quinaldate 4-oxidoreductase * : quinoline-4-carboxylate 2-oxidoreductase * EC 1.3.99.20: Now EC 1.3.7.9, 4-hydroxybenzoyl-CoA reductase * EC 1.3.99.21: Now EC 1.3.8.3, (''R'')-benzylsuccinyl-CoA dehydrogenase * EC 1.3.99.22: Now EC 1.3.98.3, coproporphyrinogen dehydrogenase * : ''all-trans''-retinol 13,14-reductase * EC 1.3.99.24: Now EC 1.3.8.16, 2-amino-4-deoxychorismate dehydrogenase * : carvone reductase * : ''all-trans''-ζ-carotene desaturase * : 1-hydroxycarotenoid 3,4-desaturase * : phytoene desaturase (neurosporene-forming) * : phytoene desaturase (zeta-carotene-forming) * : phytoene desaturase (3,4-didehydrolycopene-forming) * : phytoene desaturase (lycopene-forming) * : glutaryl-CoA dehydrogenase (non-decarboxylating) * EC 1.3.99.33: urocanate reductase * * EC 1.3.99.34: Now classified as EC 1.3.7.11, 2,3-bis-''O''-geranylgeranyl-''sn''-glycero-phospholipid reductase * EC 1.3.99.35: Now EC 1.3.7.15, chlorophyllide ''a'' reductase * * EC 1.3.99.36: cypemycin cysteine dehydrogenase (decarboxylating) * * EC 1.3.99.37: 1-hydroxy-2-isopentenylcarotenoid 3,4-desaturase * * EC 1.3.99.38: menaquinone-9 β-reductase * * EC 1.3.99.39: carotenoid φ-ring synthase * * EC 1.3.99.40: carotenoid χ-ring synthase * : *No Wikipedia article

EC 1.4 Acting on the CH-NH₂ group of donors

EC 1.4.1 With NAD⁺ or NADP⁺ as acceptor

* : alanine dehydrogenase * :

glutamate dehydrogenase Glutamate dehydrogenase (GLDH, GDH) is an enzyme observed in both prokaryotes and eukaryotic mitochondria. The aforementioned reaction also yields ammonia, which in eukaryotes is canonically processed as a substrate in the urea cycle. Typical ...

* : glutamate dehydrogenase (NAD(P)⁺) * : glutamate dehydrogenase (NADP⁺) * : L-amino-acid dehydrogenase * EC 1.4.1.6: deleted, Now included with EC 1.21.4.1, D-proline reductase (dithiol) * : serine 2-dehydrogenase * : valine dehydrogenase (NADP⁺) * : leucine dehydrogenase * :

glycine dehydrogenase In enzymology, a glycine dehydrogenase () is an enzyme that catalysis, catalyzes the chemical reaction :glycine + H2O + NAD+ \rightleftharpoons glyoxylate + NH3 + NADH + H+ The 3 substrate (biochemistry), substrates of this enzyme are glycine, wa ...

* : L-''erythro''-3,5-diaminohexanoate dehydrogenase * : 2,4-diaminopentanoate dehydrogenase * : glutamate synthase (NADPH) * : glutamate synthase (NADH) * : lysine dehydrogenase * : diaminopimelate dehydrogenase * : ''N''-methylalanine dehydrogenase * : lysine 6-dehydrogenase * : tryptophan dehydrogenase * : phenylalanine dehydrogenase * : aspartate dehydrogenase * EC 1.4.1.22: there is no overall consumption of NAD⁺ during the reaction. As a result, transfer of the enzyme from EC 4.3.1.12 was not necessary and EC 1.4.1.22 was withdrawn before being made official * : valine dehydrogenase (NAD⁺) * : 3-dehydroquinate synthase II * EC 1.4.1.25: L-arginine dehydrogenase * * EC 1.4.1.26: 2,4-diaminopentanoate dehydrogenase (NAD⁺) * * EC 1.4.1.27: glycine cleavage system * : *No Wikipedia article

EC 1.4.2 With a cytochrome as acceptor

* : glycine dehydrogenase (cytochrome)

EC 1.4.3 With oxygen as acceptor

* : D-aspartate oxidase * : L-amino-acid oxidase * : D-amino-acid oxidase * : monoamine oxidase * : pyridoxal 5′-phosphate synthase * EC 1.4.3.6: replaced by two enzymes, EC 1.4.3.21 (primary-amine oxidase) and EC 1.4.3.22 (diamine oxidase) * : D-glutamate oxidase * : ethanolamine oxidase * EC 1.4.3.9: Now included with EC 1.4.3.4 amine oxidase (flavin-containing) * : putrescine oxidase * : L-glutamate oxidase * : cyclohexylamine oxidase * : protein-lysine 6-oxidase * : L-lysine oxidase * : D-glutamate(D-aspartate) oxidase * : L-aspartate oxidase * EC 1.4.3.17: Now EC 1.3.3.10, tryptophan α,β-oxidase * EC 1.4.3.18: Not approved as the enzyme was shown to be a dehydrogenase and not an oxidase (see EC 1.5.99.12, cytokinin dehydrogenase) * : glycine oxidase * : L-lysine 6-oxidase * :

primary-amine oxidase Primary-amine oxidase, also known as semicarbazide-sensitive amine oxidase (SSAO), is an enzyme () with the systematic name ''primary-amine:oxygen oxidoreductase (deaminating)''. This enzyme catalyses the following chemical reaction : RCH2NH2 + ...

* :

diamine oxidase Diamine oxidase (DAO), also known "amine oxidase, copper-containing, 1" (AOC1), formerly called histaminase, is an enzyme () involved in the metabolism, oxidation, and inactivation of histamine and other polyamines such as putrescine or spermid ...

* : 7-chloro-L-tryptophan oxidase * : pseudooxynicotine oxidase * EC 1.4.3.25: L-arginine oxidase * * EC 1.4.3.26: pre-mycofactocin synthase * : *No Wikipedia article

EC 1.4.4 With a disulfide as acceptor

* EC 1.4.4.1: Now EC 1.21.4.1, D-proline reductase (dithiol) * : glycine dehydrogenase (aminomethyl-transferring)

EC 1.4.5 With a quinone or other compound as acceptor

* : D-amino acid dehydrogenase (quinone)

EC 1.4.7 With an iron–sulfur protein as acceptor

* : glutamate synthase (ferredoxin)

EC 1.4.9 With a copper protein as acceptor

* : methylamine dehydrogenase (amicyanin) * : aralkylamine dehydrogenase (azurin)

EC 1.4.98 With tryptophan tryptophylquinone acceptors

* : methylamine dehydrogenase (amicyanin)

EC 1.4.99 With unknown physiological acceptors

* EC 1.4.99.1: Now lEC 1.4.99.6, D-arginine dehydrogenase * : taurine dehydrogenase * EC 1.4.99.3: Now EC 1.4.9.1, methylamine dehydrogenase (amicyanin) * EC 1.4.99.4: Now EC 1.4.9.2, aralkylamine dehydrogenase (azurin) * : glycine dehydrogenase (cyanide-forming) * EC 1.4.99.6: D-arginine dehydrogenase * : *No Wikipedia article

EC 1.5 Acting on the CH-NH group of
donors A donor in general is a person, organization or government which donates something voluntarily. The term is usually used to represent a form of pure altruism, but is sometimes used when the payment for a service is recognized by all parties as r ...

EC 1.5.1 With NAD⁺ or NADP⁺ as acceptor

* : 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase AD(P)H *_:_pyrroline-5-carboxylate_reductase *_:_ AD(P)H *_:_pyrroline-5-carboxylate_reductase *_:_dihydrofolate_reductase">pyrroline-5-carboxylate_reductase.html"_;"title="AD(P)H *_:_pyrroline-5-carboxylate_reductase">AD(P)H *_:_pyrroline-5-carboxylate_reductase *_:_dihydrofolate_reductase *_EC_1.5.1.4:_Now_included_with_EC_1.5.1.3_dihydrofolate_reductase *_:_methylenetetrahydrofolate_dehydrogenase_(NADP+).html" ;"title="dihydrofolate_reductase.html" ;"title="pyrroline-5-carboxylate_reductase.html" ;"title="AD(P)H * : pyrroline-5-carboxylate reductase">AD(P)H * : pyrroline-5-carboxylate reductase * : dihydrofolate reductase">pyrroline-5-carboxylate_reductase.html" ;"title="AD(P)H * : pyrroline-5-carboxylate reductase">AD(P)H * : pyrroline-5-carboxylate reductase * : dihydrofolate reductase * EC 1.5.1.4: Now included with EC 1.5.1.3 dihydrofolate reductase * : methylenetetrahydrofolate dehydrogenase (NADP+)">methylenetetrahydrofolate dehydrogenase (NADP⁺) * : formyltetrahydrofolate dehydrogenase * : saccharopine dehydrogenase (NAD+, L-lysine-forming), saccharopine dehydrogenase (NAD⁺, L-lysine-forming) * : saccharopine dehydrogenase (NADP+, L-lysine-forming), saccharopine dehydrogenase (NADP⁺, L-lysine-forming) * : saccharopine dehydrogenase (NAD+, L-glutamate-forming), saccharopine dehydrogenase (NAD⁺, L-glutamate-forming) * : saccharopine dehydrogenase (NADP⁺, L-glutamate-forming) * : D-octopine dehydrogenase * EC 1.5.1.12: Now EC 1.2.1.88, L-glutamate γ-semialdehyde dehydrogenase * EC 1.5.1.13: Now EC 1.17.1.5, nicotinate dehydrogenase * EC 1.5.1.14: Now included with EC 1.5.1.21 Δ¹-piperideine-2-carboxylate reductase * : methylenetetrahydrofolate dehydrogenase (NAD⁺) * : D-lysopine dehydrogenase * : alanopine dehydrogenase * : ephedrine dehydrogenase * : D-nopaline dehydrogenase * : methylenetetrahydrofolate reductase (NAD(P)H) * : 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH) * : strombine dehydrogenase * : tauropine dehydrogenase * : ''N''⁵-(carboxyethyl)ornithine synthase * : thiomorpholine-carboxylate dehydrogenase * : β-alanopine dehydrogenase * :

1,2-dehydroreticulinium reductase (NADPH) In enzymology, a 1,2-dehydroreticulinium reductase (NADPH) () is an enzyme that catalyzes the chemical reaction :(R)-reticuline + NADP \rightleftharpoons 1,2-dehydroreticulinium + NADPH + H Thus, the two substrates of this enzyme are (R)-reti ...

* : opine dehydrogenase * EC 1.5.1.29: Now covered by EC 1.5.1.38 MN reductase (NADPH) EC 1.5.1.39 MN_reductase_[NAD(P)H.html" ;"title="AD(P)H.html" ;"title="MN reductase [NAD(P)H">MN reductase [NAD(P)H">AD(P)H.html" ;"title="MN reductase [NAD(P)H">MN reductase [NAD(P)Hand EC 1.5.1.41 (riboflavin reductase [NAD(P)H]) * : flavin reductase, flavin reductase (NADPH) * : berberine reductase * : vomilenine reductase * : pteridine reductase * : 6,7-dihydropteridine reductase * EC 1.5.1.35: identical to EC 1.2.1.19, aminobutyraldehyde dehydrogenase, as the substrates 1-pyrroline and 4-aminobutanal are interconvertible * : flavin reductase (NADH) * :

FAD reductase (NADH) FAD reductase (NADH) (, ''NADH-FAD reductase'', ''NADH-dependent FAD reductase'') is an enzyme with systematic name ''FADH2:NAD+ oxidoreductase''. This enzyme catalyses the following chemical reaction A chemical reaction is a process that lea ...

* : FMN reductase (NADPH) * :

FMN reductase (NAD(P)H) FMN reductase (NAD(P)H) (, ''FRG'') is an enzyme with systematic name ''FMNH2:NAD(P)+ oxidoreductase''. This enzyme catalyses the following chemical reaction A chemical reaction is a process that leads to the chemical transformation of one se ...

* : 8-hydroxy-5-deazaflavin:NADPH oxidoreductase * : riboflavin reductase (NAD(P)H) * : FMN reductase (NADH) * : carboxynorspermidine synthase * : festuclavine dehydrogenase * : FAD reductase (NAD(P)H) * EC 1.5.1.46: agroclavine dehydrogenase * * EC 1.5.1.47: dihydromethanopterin reductase AD(P)⁺* * EC 1.5.1.48: 2-methyl-1-pyrroline reductase * * EC 1.5.1.49: 1-pyrroline-2-carboxylate reductase AD(P)H* * EC 1.5.1.50: dihydromonapterin reductase * * EC 1.5.1.51: ''N''- 2''S'')-2-amino-2-carboxyethylL-lutamate dehydrogenase * * EC 1.5.1.52: staphylopine dehydrogenase * * EC 1.5.1.53: methylenetetrahydrofolate reductase (NADPH) * * EC 1.5.1.54: methylenetetrahydrofolate reductase (NADH) * : *No Wikipedia article

EC 1.5.3 With oxygen as acceptor

* : sarcosine oxidase * : ''N''-methyl-L-amino-acid oxidase * EC 1.5.3.3: deleted * : ''N''⁶-methyl-lysine oxidase * : (''S'')-6-hydroxynicotine oxidase * : (''R'')-6-hydroxynicotine oxidase * : L-pipecolate oxidase * EC 1.5.3.8: Now included with EC 1.3.3.8, tetrahydroberberine oxidase * EC 1.5.3.9: Now EC 1.21.3.3, reticuline oxidase * : dimethylglycine oxidase * EC 1.5.3.11: Now included with EC 1.5.3.13 (''N''¹-acetylpolyamine oxidase), EC 1.5.3.14 (polyamine oxidase (propane-1,3-diamine-forming)), EC 1.5.3.15 (''N''⁸-acetylspermidine oxidase (propane-1,3-diamine-forming)), EC 1.5.3.16 (spermine oxidase) and EC 1.5.3.17 (non-specific polyamine oxidase) * : dihydrobenzophenanthridine oxidase * : N¹-acetylpolyamine oxidase * : polyamine oxidase (propane-1,3-diamine-forming) * : ''N''⁸-acetylspermidine oxidase (propane-1,3-diamine-forming) * : spermine oxidase * : non-specific polyamine oxidase * : L-saccharopine oxidase * : 4-methylaminobutanoate oxidase (formaldehyde-forming) * : ''N''-alkylglycine oxidase * : 4-methylaminobutanoate oxidase (methylamine-forming) * EC 1.5.3.22: coenzyme F₄₂₀H₂ oxidase * * EC 1.5.3.23: glyphosate oxidoreductase * : *No Wikipedia article

EC 1.5.4 With a disulfide as acceptor

* : pyrimidodiazepine synthase

EC 1.5.5 With a quinone or similar compound as acceptor

* :

electron-transferring-flavoprotein dehydrogenase Electron-transferring-flavoprotein dehydrogenase (''ETF dehydrogenase'' or ''electron transfer flavoprotein-ubiquinone oxidoreductase'', ) is an enzyme that transfers electrons from electron-transferring flavoprotein in the mitochondrial matrix, t ...

* EC 1.5.5.2: proline dehydrogenase * * EC 1.5.5.3: hydroxyproline dehydrogenase * : *No Wikipedia article

EC 1.5.7 With an iron–sulfur protein as acceptor

* : methylenetetrahydrofolate reductase (ferredoxin) * EC 1.5.7.2: coenzyme F₄₂₀ oxidoreductase (ferredoxin) * : *No Wikipedia article

EC 1.5.8 With a flavin or flavoprotein as acceptor

* : dimethylamine dehydrogenase * : trimethylamine dehydrogenase * :

sarcosine dehydrogenase In enzymology, sarcosine dehydrogenase () is a mitochondrial enzyme that catalyzes the chemical reaction N-demethylation of sarcosine to give glycine. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH g ...

* : dimethylglycine dehydrogenase

EC 1.5.98 With other, known, physiological acceptors

* EC 1.5.98.1: ethylenetetrahydromethanopterin dehydrogenase * EC 1.5.98.2: 5,10-methylenetetrahydromethanopterin reductase * EC 1.5.98.3: coenzyme F₄₂₀:methanophenazine dehydrogenase

EC 1.5.99 With unknown physiological acceptors

* EC 1.5.99.1: Now EC 1.5.8.3, sarcosine dehydrogenase * EC 1.5.99.2: Now EC 1.5.8.4, dimethylglycine dehydrogenase * : L-pipecolate dehydrogenase * : nicotine dehydrogenase * : methylglutamate dehydrogenase * : spermidine dehydrogenase * EC 1.5.99.7: Now EC 1.5.8.2, trimethylamine dehydrogenase * EC 1.5.99.8: Now EC 1.5.5.2, proline dehydrogenase * EC 1.5.99.9: transferred to EC 1.5.98.1, methylenetetrahydromethanopterin dehydrogenase * EC 1.5.99.10: Now EC 1.5.8.1, dimethylamine dehydrogenase * EC 1.5.99.11: transferred to EC 1.5.98.2, 5,10-methylenetetrahydromethanopterin reductase * : cytokinin dehydrogenase * : D-proline dehydrogenase, D-proline dehydrogenase * : 6-hydroxypseudooxynicotine dehydrogenase * EC 1.5.99.15: dihydromethanopterin reductase (acceptor) * : *No Wikipedia article

EC 1.6 Acting on NADH or NADPH

EC 1.6.1 With NAD or NADP as acceptor

* : NAD(P)+ transhydrogenase (Si-specific), NAD(P)⁺ transhydrogenase (''Si''-specific) * : NAD(P)+ transhydrogenase (Re/Si-specific), NAD(P)⁺ transhydrogenase (''Re''/''Si''-specific)

EC 1.6.2 With a heme protein as acceptor

* EC 1.6.2.1: now EC 1.6.99.3 NADH dehydrogenase * : cytochrome-b5 reductase, cytochrome-''b''₅ reductase * EC 1.6.2.3: deleted * : NADPH—hemoprotein reductase * : NADPH—cytochrome-c2 reductase, NADPH—cytochrome-''c''₂ reductase * : leghemoglobin reductase

EC 1.6.3 With oxygen as acceptor

* : NAD(P)H oxidase, NAD(P)H oxidase (H₂O₂-forming) * EC 1.6.3.2: NAD(P)H oxidase (H₂O-forming) * * EC 1.6.3.3: NADH oxidase (H₂O₂-forming) * * EC 1.6.3.4: NADH oxidase (H₂O-forming) * * EC 1.6.3.5: renalase * : *No Wikipedia article

EC 1.6.4 With a disulfide as acceptor (deleted sub-class)

* EC 1.6.4.1: now cystine reductase * EC 1.6.4.2: now glutathione-disulfide reductase * EC 1.6.4.3: now dihydrolipoyl dehydrogenase * EC 1.6.4.4: now protein-disulfide reductase * EC 1.6.4.5: now thioredoxin-disulfide reductase * EC 1.6.4.6: now CoA-glutathione reductase * EC 1.6.4.7: now asparagusate reductase * EC 1.6.4.8: now trypanothione-disulfide reductase * EC 1.6.4.9: now bis-γ-glutamylcystine reductase * EC 1.6.4.10: now CoA-disulfide reductase

EC 1.6.5 With a quinone or similar compound as acceptor

* EC 1.6.5.1: deleted * : NAD(P)H dehydrogenase (quinone) * EC 1.6.5.3: now NADH:ubiquinone reductase (H⁺-translocating) * : monodehydroascorbate reductase (NADH) * : NADPH:quinone reductase * : p-benzoquinone reductase (NADPH), ''p''-benzoquinone reductase (NADPH) * : 2-hydroxy-1,4-benzoquinone reductase * : Now , NADH:ubiquinone reductase (Na⁺-transporting) * : NADH:ubiquinone reductase (non-electrogenic) * : NADPH dehydrogenase (quinone) * EC 1.6.5.11: Identical to , NADH:quinone reductase (non-electrogenic) * * EC 1.6.5.12: demethylphylloquinone reductase * : *No Wikipedia article

EC 1.6.6 With a nitrogenous group as acceptor

* EC 1.6.6.1: Now , nitrate reductase (NADH) * EC 1.6.6.2: Now , nitrate reductase AD(P)H* EC 1.6.6.3: Now , nitrate reductase (NADPH) * EC 1.6.6.4: Now , nitrite reductase AD(P)H* EC 1.6.6.5: Now , nitrite reductase (NO-forming) * EC 1.6.6.6: Now , hyponitrite reductase * EC 1.6.6.7: Now , azobenzene reductase * EC 1.6.6.8: Now , GMP reductase * EC 1.6.6.9: Now known to be catalysed by , trimethylamine-''N''-oxide reductase * EC 1.6.6.10: Now , nitroquinoline-''N''-oxide reductase] * EC 1.6.6.11: Now , hydroxylamine reductase (NADH) * EC 1.6.6.12: Now , 4-(dimethylamino)phenylazoxybenzene reductase * EC 1.6.6.13: Now , ''N''-hydroxy-2-acetamidofluorene reductase

EC 1.6.7 With an iron–sulfur protein as acceptor (deleted sub-subclass)

* EC 1.6.7.1: now ferredoxin—NADP⁺ reductase * EC 1.6.7.2: now rubredoxin—NAD⁺ reductase * EC 1.6.7.3: now ferredoxin—NAD⁺ reductase

EC 1.6.8 With a flavin as acceptor (deleted sub-subclass)

* EC 1.6.8.1: Now FMN reductase * EC 1.6.8.2: Now flavin reductase

EC 1.6.99 With unknown physiological acceptors

* : NADPH dehydrogenase * EC 1.6.99.2: Now , NAD(P)H dehydrogenase (quinone * EC 1.6.99.3: The activity is covered by , NADH:ubiquinone reductase (H⁺-translocating) * EC 1.6.99.4: Now , ferredoxin—NADP⁺ reductase * EC 1.6.99.5: Now , NADH dehydrogenase (quinone) * EC 1.6.99.6: Now , NADPH dehydrogenase (quinone) * EC 1.6.99.7: Now , 6,7-dihydropteridine reductase * EC 1.6.99.8: Deleted * EC 1.6.99.9: Now , cob(II)alamin reductase * EC 1.6.99.10: included in , 6,7-dihydropteridine reductase * EC 1.6.99.11: Deleted * EC 1.6.99.12: Now , cyanocobalamin reductase (cyanide-eliminating) * EC 1.6.99.13: Now , ferric-chelate reductase

EC 1.7 Acting on other nitrogenous compounds as donors

EC 1.7.1 With NAD⁺ or NADP⁺ as acceptor

* : nitrate reductase (NADH) * : nitrate reductase (NAD(P)H) * : nitrate reductase (NADPH) * : nitrite reductase (NAD(P)H) * : hyponitrite reductase * : azobenzene reductase * : GMP reductase * EC 1.7.1.8: deleted * : nitroquinoline-N-oxide reductase, nitroquinoline-''N''-oxide reductase * : hydroxylamine reductase (NADH) * : 4-(dimethylamino)phenylazoxybenzene reductase * : N-hydroxy-2-acetamidofluorene reductase, ''N''-hydroxy-2-acetamidofluorene reductase * : preQ1 synthase, preQ₁ synthase * : nitric oxide reductase (NAD(P), nitrous oxide-forming) * : nitrite reductase (NADH) * : nitrobenzene nitroreductase * : FMN-dependent NADH-azoreductase

EC 1.7.2 With a cytochrome as acceptor

* : nitrite reductase (NO-forming) * : Cytochrome c nitrite reductase, nitrite reductase (cytochrome; ammonia-forming) * : trimethylamine-N-oxide reductase (cytochrome c), trimethylamine-''N''-oxide reductase * : nitrous-oxide reductase * : nitric oxide reductase (cytochrome c), nitric oxide reductase (cytochrome ''c'') * : hydroxylamine dehydrogenase * : hydrazine synthase * * : hydrazine dehydrogenase * : *No Wikipedia article

EC 1.7.3 With oxygen as acceptor

* : nitroalkane oxidase * : acetylindoxyl oxidase * : urate oxidase, factor-independent urate hydroxylase * EC 1.7.3.4: Now covered by , hydroxylamine dehydrogenase, and , hydroxylamine oxidase (cytochrome) * : 3-aci-nitropropanoate oxidase, 3-''aci''-nitropropanoate oxidase * : hydroxylamine oxidase (cytochrome) * : *No Wikipedia article

EC 1.7.5 With a quinone or similar compound as acceptor

* : nitrate reductase (quinone) * : nitric oxide reductase (menaquinol)

EC 1.7.6 With a nitrogenous group as acceptor

* : nitrite dismutase

EC 1.7.7 With an iron–sulfur protein as acceptor

* : ferredoxin—nitrite reductase * : ferredoxin—nitrate reductase

EC 1.7.99 With other acceptors

* : hydroxylamine reductase * EC 1.7.99.2: deleted: reaction may have been due to the combined action of nitrous-oxide reductase and nitric-oxide reductase * EC 1.7.99.3: Now included with , nitrite reductase (NO-forming) * EC 1.7.99.4: Now , nitrate reductase (NADH), , nitrate reductase [NAD(P)H], , nitrate reductase (NADPH), , nitrate reductase (quinone), , nitrate reductase (ferredoxin) and , nitrate reductase (cytochrome) * EC 1.7.99.5: Now included with , methylenetetrahydrofolate reductase AD(P)H* EC 1.7.99.6: Now nitrous-oxide reductase * EC 1.7.99.7: Now nitric oxide reductase (cytochrome ''c'') * : hydroxylamine oxidoreductase * EC 1.7.99.8: Now classified as , hydrazine dehydrogenase

EC 1.8 Acting on a sulfur group of donors

EC 1.8.1 With NAD⁺ or NADP⁺ as acceptor

* EC 1.8.1.1: deleted * : sulfite reductase (NADPH) * : hypotaurine dehydrogenase * : dihydrolipoyl dehydrogenase * : 2-oxopropyl-CoM reductase (carboxylating) * : cystine reductase * : glutathione-disulfide reductase * : protein-disulfide reductase * : thioredoxin-disulfide reductase * : CoA-glutathione reductase * : asparagusate reductase * : trypanothione-disulfide reductase * : bis-g-glutamylcystine reductase, bis-γ-glutamylcystine reductase * : CoA-disulfide reductase * : mycothione reductase * : glutathione amide reductase * : dimethylsulfone reductase * : NAD(P)H sulfur oxidoreductase (CoA-dependent) * * : sulfide dehydrogenase * * : 4,4′-dithiodibutanoate disulfide reductase * * : dissimilatory dimethyldisulfide reductase * : *No Wikipedia article

EC 1.8.2 With a cytochrome as acceptor

* : sulfite dehydrogenase, sulfite dehydrogenase (cytochrome) * : thiosulfate dehydrogenase * : sulfide-cytochrome-c reductase (flavocytochrome c), sulfide-cytochrome-''c'' reductase (flavocytochrome ''c'') * : dimethyl sulfide:cytochrome ''c''₂ reductase * * : thiosulfate reductase (cytochrome) * * : ''S''-disulfanyl-L-cysteine oxidoreductase * * : thiocyanate desulfurase * : *No Wikipedia article

EC 1.8.3 With oxygen as acceptor

* : sulfite oxidase * : thiol oxidase * : glutathione oxidase * : methanethiol oxidase * : prenylcysteine oxidase * : farnesylcysteine lyase * : formylglycine-generating enzyme * : *No Wikipedia article

EC 1.8.4 With a disulfide as acceptor

* : glutathione—homocystine transhydrogenase * : protein-disulfide reductase (glutathione) * : glutathione—CoA-glutathione transhydrogenase * : glutathione—cystine transhydrogenase * EC 1.8.4.5: Now , L-methionine (''S'')-''S''-oxide reductase and , L-methionine (''R'')-''S''-oxide reductase * EC 1.8.4.6: due to , peptide-methionine (''S'')-''S''-oxide reductase * : enzyme-thiol transhydrogenase (glutathione-disulfide) * : phosphoadenylyl-sulfate reductase (thioredoxin) * : adenylyl-sulfate reductase (glutathione) * : adenylyl-sulfate reductase (thioredoxin) * : peptide-methionine (S)-S-oxide reductase, peptide-methionine (''S'')-''S''-oxide reductase * : peptide-methionine (R)-S-oxide reductase, peptide-methionine (''R'')-''S''-oxide reductase * : L-methionine (S)-S-oxide reductase, L-methionine (''S'')-''S''-oxide reductase * : L-methionine (R)-S-oxide reductase, L-methionine (''R'')-''S''-oxide reductase * : protein dithiol oxidoreductase (disulfide-forming) * * : thioredoxin:protein disulfide reductase * : *No Wikipedia article

EC 1.8.5 With a quinone or similar compound as acceptor

* : glutathione dehydrogenase (ascorbate) * : thiosulfate dehydrogenase (quinone) * : dimethylsulfoxide reductase, respiratory dimethylsulfoxide reductase * : sulfide:quinone reductase, bacterial sulfide:quinone reductase * : thiosulfate reductase (quinone) * * : sulfite dehydrogenase (quinone) * * : glutathionyl-hydroquinone reductase * * : eukaryotic sulfide quinone oxidoreductase * * : protein dithiol:quinone oxidoreductase DsbB * : *No Wikipedia article

EC 1.8.6 With a nitrogenous group as acceptor (deleted sub-subclass)

* : Now included with glutathione transferase

EC 1.8.7 With an iron–sulfur protein as acceptor

* : sulfite reductase (ferredoxin), assimilatory sulfite reductase (ferredoxin) * : ferredoxin:thioredoxin reductase * : ferredoxin:CoB-CoM heterodisulfide reductase * : *No Wikipedia article

EC 1.8.98 With other, known, acceptors

* : CoB—CoM heterodisulfide reductase, dihydromethanophenazine:CoB-CoM heterodisulfide reductase * : sulfiredoxin

EC 1.8.99 With other acceptors

* EC 1.8.99.1: Now covered by , assimilatory sulfite reductase (NADPH) and , assimilatory sulfite reductase (ferredoxin) * : adenylyl-sulfate reductase * EC 1.8.99.3: an ''in vitro'' artifact of , dissimilatory sulfite reductase * EC 1.8.99.4: Now , phosphoadenylyl-sulfate reductase (thioredoxin) * EC 1.8.99.5: dissimilatory sulfite reductase * : *No Wikipedia article

EC 1.9 Acting on a heme group of donors

EC 1.9.3 With oxygen as acceptor

* EC 1.9.3.1: Now , cytochrome-''c'' oxidase * EC 1.9.3.2: Now included with , nitrite reductase (NO-forming)

EC 1.9.6 With a nitrogenous group as acceptor

* : nitrate reductase (cytochrome)

EC 1.9.98 With other, known, physiological acceptors

* : iron—cytochrome-''c'' reductase

EC 1.9.99 With other acceptors

* EC 1.9.99.1: Now , iron—cytochrome-''c'' reductase

EC 1.10 Acting on diphenols and related substances as donors

EC 1.10.1 With NAD⁺ or NADP⁺ as acceptor

* : trans-acenaphthene-1,2-diol dehydrogenase, ''trans''-acenaphthene-1,2-diol dehydrogenase

EC 1.10.2 With a cytochrome as acceptor

* EC 1.10.2.1: The activity is covered by , ascorbate ferrireductase (transmembrane) * EC 1.10.2.2: Now , quinol—cytochrome-''c'' reductase

EC 1.10.3 With oxygen as acceptor

* : catechol oxidase * : laccase * : L-ascorbate oxidase, L-ascorbate oxidase * : o-aminophenol oxidase, ''o''-aminophenol oxidase * : 3-hydroxyanthranilate oxidase * : rifamycin-B oxidase * EC 1.10.3.7: Now , sulochrin oxidase [(+)-bisdechlorogeodin-forming] * EC 1.10.3.8: Now , sulochrin oxidase [(-)-bisdechlorogeodin-forming] * : photosystem II * EC 1.10.3.10: Now , ubiquinol oxidase (H⁺-transporting) * : ubiquinol oxidase (non-electrogenic) * : Now , menaquinol oxidase (H⁺-transporting) * EC 1.10.3.13: Now , caldariellaquinol oxidase (H⁺-transporting) * EC 1.10.3.14: Now , ubiquinol oxidase (electrogenic, proton-motive force generating) * : grixazone synthase * * : dihydrophenazinedicarboxylate synthase * * : superoxide oxidase * : *No Wikipedia article

EC 1.10.5 With a quinone or related compound as acceptor

* : ribosyldihydronicotinamide dehydrogenase (quinone) : *No Wikipedia article

EC 1.10.9 With a copper protein as acceptor

* EC 1.10.9.1: Now , plastoquinol—plastocyanin reductase

EC 1.10.99 With unknown physiological acceptors

* EC 1.10.99.1: Now plastoquinol—plastocyanin reductase * EC 1.10.99.2: Now ribosyldihydronicotinamide dehydrogenase (quinone) * EC 1.10.99.3: Now violaxanthin de-epoxidase

EC 1.11 Acting on a peroxide as acceptor

EC 1.11.1 Peroxidases

* : NADH peroxidase * : NADPH peroxidase * : fatty-acid peroxidase * EC 1.11.1.4: Now tryptophan 2,3-dioxygenase * : cytochrome-c peroxidase, cytochrome-''c'' peroxidase * : catalase * : peroxidase * : iodide peroxidase * : glutathione peroxidase * : chloride peroxidase * : L-ascorbate peroxidase, L-ascorbate peroxidase * : phospholipid-hydroperoxide glutathione peroxidase * : manganese peroxidase * : diarylpropane peroxidase, lignin peroxidase * EC 1.11.1.15: Now described by , thioredoxin-dependent peroxiredoxin; , glutaredoxin-dependent peroxiredoxin; , NADH-dependent peroxiredoxin; , glutathione-dependent peroxiredoxin; , lipoyl-dependent peroxiredoxin; and , mycoredoxin-dependent peroxiredoxin * : versatile peroxidase * : glutathione amide-dependent peroxidase * : bromide peroxidase * : dye decolorizing peroxidase * : prostamide/prostaglandin F2alpha synthase, prostamide/prostaglandin F_2α synthase * : catalase-peroxidase * : hydroperoxy fatty acid reductase * * : (''S'')-2-hydroxypropylphosphonic acid epoxidase * * : thioredoxin-dependent peroxiredoxin * * : glutaredoxin-dependent peroxiredoxin * * : NADH-dependent peroxiredoxin * * : glutathione-dependent peroxiredoxin * * : lipoyl-dependent peroxiredoxin * * : mycoredoxin-dependent peroxiredoxin * : *No Wikipedia article

EC 1.11.2 Peroxygenase

* : unspecific peroxygenase * : myeloperoxidase * : plant seed peroxygenase * : fatty-acid peroxygenase * : 3-methyl-L-tyrosine peroxygenase * * : L-tyrosine peroxygenase * : *No Wikipedia article

EC 1.12 Acting on hydrogen as donor

EC 1.12.1 With NAD⁺ or NADP⁺ as acceptor

* : Now EC 1.12.7.2, ferredoxin hydrogenase * : hydrogen dehydrogenase * : hydrogen dehydrogenase (NADP+), hydrogen dehydrogenase (NADP⁺) * : hydrogenase (NAD+, ferredoxin), hydrogenase (NAD⁺, ferredoxin) * : hydrogen dehydrogenase AD(P)⁺* : *No Wikipedia article

EC 1.12.2 With a cytochrome as acceptor

* : cytochrome-c3 hydrogenase, cytochrome-''c''₃ hydrogenase

EC 1.12.5 With a quinone or similar compound as acceptor

* : hydrogen:quinone oxidoreductase

EC 1.12.7 With an iron–sulfur protein as acceptor

* EC 1.12.7.1: Now , ferredoxin hydrogenase * : ferredoxin hydrogenase

EC 1.12.98 With other known acceptors

* : coenzyme F420 hydrogenase, coenzyme F₄₂₀ hydrogenase * : 5,10-methenyltetrahydromethanopterin hydrogenase * : Methanosarcina-phenazine hydrogenase, ''Methanosarcina''-phenazine hydrogenase * : Sulfhydrogenase

EC 1.12.99 With unknown physiological acceptors

* EC 1.12.99.1: Now , coenzyme F₄₂₀ hydrogenase * EC 1.12.99.2: Now shown to be two enzymes, , ''Methanosarcina''-phenazine hydrogenase and , CoB—CoM heterodisulfide reductase * EC 1.12.99.3: Now , hydrogen:quinone oxidoreductase * EC 1.12.99.4: Now , 5,10-methenyltetrahydromethanopterin hydrogenase * EC 1.12.99.5: Identical to , 3-hydroxy-4-oxoquinoline 2,4-dioxygenase * : hydrogenase (acceptor)

EC 1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

EC 1.13.11 With incorporation of two atoms of oxygen

* : catechol 1,2-dioxygenase * : catechol 2,3-dioxygenase * : protocatechuate 3,4-dioxygenase * : gentisate 1,2-dioxygenase * : homogentisate 1,2-dioxygenase * : 3-hydroxyanthranilate 3,4-dioxygenase * EC 1.13.11.7: deleted * : protocatechuate 4,5-dioxygenase * : 2,5-dihydroxypyridine 5,6-dioxygenase * : 7,8-dihydroxykynurenate 8,8a-dioxygenase * : tryptophan 2,3-dioxygenase * : lipoxygenase, linoleate 13S-lipoxygenas * EC 1.13.11.13: The activity is the sum of several enzymatic and spontaneous reactions * : 2,3-dihydroxybenzoate 3,4-dioxygenase * : 3,4-dihydroxyphenylacetate 2,3-dioxygenase * : 3-carboxyethylcatechol 2,3-dioxygenase * : indole 2,3-dioxygenase * : sulfur dioxygenase, persulfide dioxygenase * : cysteamine dioxygenase * : cysteine dioxygenase * EC 1.13.11.21: Now , β-carotene 15,15′-monooxygenase * : caffeate 3,4-dioxygenase * : 2,3-dihydroxyindole 2,3-dioxygenase * : quercetin 2,3-dioxygenase * : 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase * : peptide-tryptophan 2,3-dioxygenase * : 4-hydroxyphenylpyruvate dioxygenase * : 2,3-dihydroxybenzoate 2,3-dioxygenase * : stizolobate synthase * : stizolobinate synthase * : arachidonate 12-lipoxygenase * EC 1.13.11.32: Now , nitronate monooxygenase * : arachidonate 15-lipoxygenase * : arachidonate 5-lipoxygenase * : pyrogallol 1,2-oxygenase * : chloridazon-catechol dioxygenase * : hydroxyquinol 1,2-dioxygenase * : 1-hydroxy-2-naphthoate 1,2-dioxygenase * : biphenyl-2,3-diol 1,2-dioxygenase * : arachidonate 8-lipoxygenase * : 2,4'-dihydroxyacetophenone dioxygenase, 2,4′-dihydroxyacetophenone dioxygenase * EC 1.13.11.42: identical to , tryptophan 2,3-dioxygenase * : lignostilbene ab-dioxygenase, lignostilbene αβ-dioxygenase * EC 1.13.11.44: Activity is covered by , linoleate 8''R''-lipoxygenase and , 9,12-octadecadienoate 8-hydroperoxide 8''S''-isomerase * : linoleate 11-lipoxygenase * : 4-hydroxymandelate synthase * : 3-hydroxy-4-oxoquinoline 2,4-dioxygenase * : 3-hydroxy-2-methyl-quinolin-4-one 2,4-dioxygenase * : chlorite O2-lyase, chlorite O₂-lyase * : acetylacetone-cleaving enzyme * : 9-cis-epoxycarotenoid dioxygenase, 9-''cis''-epoxycarotenoid dioxygenase * : indoleamine 2,3-dioxygenase * : Acireductone dioxygenase (Ni2+-requiring), acireductone dioxygenase (Ni²⁺-requiring) * : acireductone dioxygenase (Fe(2+)-requiring), acireductone dioxygenase [iron(II)-requiring] * : sulfur oxygenase/reductase * : 1,2-dihydroxynaphthalene dioxygenase * : gallate dioxygenase * : linoleate 9S-lipoxygenase, linoleate 9''S''-lipoxygenase * : torulene dioxygenase * : linoleate 8R-lipoxygenase, inoleate 8''R''-lipoxygenase * : linolenate 9R-lipoxygenase, linolenate 9''R''-lipoxygenase * : linoleate 10R-lipoxygenase, linoleate 10''R''-lipoxygenase * : beta-carotene 15,15'-dioxygenase, β-carotene 15,15′-dioxygenase * : 5-nitrosalicylate dioxygenase * : carotenoid isomerooxygenase * : hydroquinone 1,2-dioxygenase * : 8'-apo-beta-carotenoid 14',13'-cleaving dioxygenase, 8′-apo-β-carotenoid 14′,13′-cleaving dioxygenase * : 9-cis-beta-carotene 9',10'-cleaving dioxygenase, 9-''cis''-β-carotene 9′,10′-cleaving dioxygenase * : carlactone synthase * : all-trans-10'-apo-beta-carotenal 13,14-cleaving dioxygenase, ''all-trans''-10′-apo-β-carotenal 13,14-cleaving dioxygenase * : carotenoid-9',10'-cleaving dioxygenase, carotenoid-9′,10′-cleaving dioxygenase * : 2-hydroxyethylphosphonate dioxygenase * : methylphosphonate synthase * : 2-aminophenol 1,6-dioxygenase * * : ''all-trans''-8′-apo-β-carotenal 15,15′-oxygenase * * : 2-amino-5-chlorophenol 1,6-dioxygenase * * : oleate 10''S''-lipoxygenase * * : 2-amino-1-hydroxyethylphosphonate dioxygenase (glycine-forming) * * : aerobic 5,6-dimethylbenzimidazole synthase * * : (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase * * : 7,8-dihydroneopterin oxygenase * * : 8′-apo-carotenoid 13,14-cleaving dioxygenase * * : 4-hydroxy-3-prenylphenylpyruvate oxygenase * * : crocetin dialdehyde synthase * * : exo-cleaving rubber dioxygenase * * : 5-aminosalicylate 1,2-dioxygenase * * : endo-cleaving rubber dioxygenase * * : isoeugenol monooxygenase * * : (hydroxymethyl)phosphonate dioxygenase * * : [1-hydroxy-2-(trimethylamino)ethyl]phosphonate dioxygenase (glycine-betaine-forming) * * : 3-mercaptopropionate dioxygenase * * : fatty acid α-dioxygenase * : *No Wikipedia article

EC 1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)

* : arginine 2-monooxygenase * : lysine 2-monooxygenase * : tryptophan 2-monooxygenase * : lactate 2-monooxygenase * : Renilla-luciferin 2-monooxygenase, ''Renilla''-type luciferase * : Cypridina-luciferin 2-monooxygenase, ''Cypridina''-luciferin 2-monooxygenase * : Photinus-luciferin 4-monooxygenase (ATP-hydrolysing), firefly luciferase * : Watasenia-luciferin 2-monooxygenase, ''Watasenia''-luciferin 2-monooxygenase * : phenylalanine 2-monooxygenase * EC 1.13.12.10: Reaction covered by , L-lysine 6-monooxygenase (NADPH) * EC n1.13.12.11: The activity is due to , flavin-containing monooxygenase * EC 1.13.12.12: transferred to , 8-apo-β-carotenoid 14′,13′-cleaving dioxygenase * : Oplophorus-luciferin 2-monooxygenase, ''Oplophorus''-luciferin 2-monooxygenase * EC 1.13.12.14: Now , chlorophyllide-a oxygenase * : 3,4-dihydroxyphenylalanine oxidative deaminase * : nitronate monooxygenase * : dichloroarcyriaflavin A synthase * : dinoflagellate luciferase * : 2-oxoglutarate dioxygenase (ethylene-forming), 2-oxoglutarate dioxygenase (ethene-forming) * : noranthrone monooxygenase * * : tetracenomycin-F1 monooxygenase * * : deoxynogalonate monooxygenase * * : 4-hydroxy-3-prenylbenzoate synthase * * : calcium-regulated photoprotein * : *No Wikipedia article

EC 1.13.99 Miscellaneous

* : inositol oxygenase * EC 1.13.99.2: Now , benzoate 1,2-dioxygenase * : tryptophan 2'-dioxygenase, tryptophan 2′-dioxygenase * EC 1.13.99.4: Now , 4-chlorophenylacetate 3,4-dioxygenase * EC 1.13.99.5: now , 3-hydroxy-4-oxoquinoline 2,4-dioxygenase

EC 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

EC 1.14.1 With NADH or NADPH as one donor (deleted sub-subclass)

* EC 1.14.1.1: now , unspecific monooxygenase * EC 1.14.1.2: now , kynurenine 3-monooxygenase * EC 1.14.1.3: deleted, covered by , squalene monooxygenase and , lanosterol synthase * EC 1.14.1.4: now , kynurenine 7,8-hydroxylase * EC 1.14.1.5: now ; imidazoleacetate 4-monooxygenase * EC 1.14.1.6: now , steroid 11β-monooxygenase * EC 1.14.1.7: now , steroid 17α-monooxygenase * EC 1.14.1.8: now , steroid 21-monooxygenase * EC 1.14.1.9: deleted * EC 1.14.1.10: now estradiol 6β-monooxygenase * EC 1.14.1.11: deleted

EC 1.14.2 With ascorbate as one donor (deleted sub-subclass)

* EC 1.14.2.1: now , dopamine β-monooxygenase * EC 1.14.2.2: now , 4-hydroxyphenylpyruvate dioxygenase

EC 1.14.3 With reduced pteridine as one donor (deleted sub-subclass)

* EC 1.14.3.1: now , phenylalanine 4-monooxygenase

EC 1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors

* : g-butyrobetaine dioxygenase, γ-butyrobetaine dioxygenase * : procollagen-proline dioxygenase * : pyrimidine-deoxynucleoside 2'-dioxygenase, pyrimidine-deoxynucleoside 2′-dioxygenase * : procollagen-lysine 5-dioxygenase * EC 1.14.11.5: Now included with thymine dioxygenase * : thymine dioxygenase * : procollagen-proline 3-dioxygenase * : trimethyllysine dioxygenase * : flavanone 3-dioxygenase * : pyrimidine-deoxynucleoside 1'-dioxygenase, pyrimidine-deoxynucleoside 1′-dioxygenase * : hyoscyamine (6S)-dioxygenase, hyoscyamine (6''S'')-dioxygenase * : gibberellin-44 dioxygenase * : gibberellin 2b-dioxygenase, gibberellin 2β-dioxygenase * EC 1.14.11.14: Now , 6β-hydroxyhyoscyamine epoxidase * : gibberellin 3b-dioxygenase, gibberellin 3β-dioxygenase * : peptide-aspartate b-dioxygenase, peptide-aspartate β-dioxygenase * : taurine dioxygenase * : phytanoyl-CoA dioxygenase * EC 1.14.11.19: Now , anthocyanidin synthase * : deacetoxyvindoline 4-hydroxylase * : clavaminate synthase * EC 1.14.11.22: Now , flavone synthase * EC 1.14.11.23: Now , flavonol synthase * : 2'-deoxymugineic-acid 2'-dioxygenase, 2′-deoxymugineic-acid 2′-dioxygenase * : mugineic-acid 3-dioxygenase * : deacetoxycephalosporin-C hydroxylase * : (histone-H3)-lysine-36 demethylase, [histone H3]-dimethyl-L-lysine³⁶ demethylase * : proline 3-hydroxylase * : hypoxia-inducible factor-proline dioxygenase * : hypoxia-inducible factor-asparagine dioxygenase * : thebaine 6-O-demethylase, thebaine 6-''O''-demethylase * : codeine 3-O-demethylase, codeine 3-''O''-demethylase * : DNA oxidative demethylase * EC 1.14.11.34: Now , 2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming) * : 1-deoxypentalenic acid 11beta-hydroxylase, 1-deoxypentalenic acid 11β-hydroxylase * : pentalenolactone F synthase * : pentalenolactone F synthase * * : kanamycin B dioxygenase * * : verruculogen synthase * * : L-asparagine hydroxylase * * : enduracididine β-hydroxylase * * : L-arginine hydroxylase * * : tRNA^Phe (7-(3-amino-3-carboxypropyl)wyosine³⁷-''C''²)-hydroxylase * * : (''S'')-dichlorprop dioxygenase (2-oxoglutarate) * * : (''R'')-dichlorprop dioxygenase (2-oxoglutarate) * * : L-isoleucine 4-hydroxylase * * : 2-aminoethylphosphonate dioxygenase * * : [50S ribosomal protein L16]-arginine 3-hydroxylase * * : xanthine dioxygenase * * : uridine-5′-phosphate dioxygenase * * EC, 1.14.11.50: Now , (–)-deoxypodophyllotoxin synthase * : DNA ''N''⁶-methyladenine demethylase * * : validamycin A dioxygenase * * : mRNA ''N''⁶-methyladenine demethylase * * : mRNA ''N''¹-methyladenine demethylase * * : ectoine hydroxylase * * : L-proline ''cis''-4-hydroxylase * * : L-proline ''trans''-4-hydroxylase * * : ornithine lipid ester-linked acyl 2-hydroxylase * * : 2,4-dihydroxy-1,4-benzoxazin-3-one-glucoside dioxygenase * * : scopoletin 8-hydroxylase * * : feruloyl-CoA 6-hydroxylase * * : ''trans''-4-coumaroyl-CoA 2-hydroxylase * * : peptidyl-lysine (3''S'')-dioxygenase * * : glutarate dioxygenase * * : [histone H3]-dimethyl-L-lysine⁹ demethylase * * : [histone H3]-trimethylL-lysine⁹ demethylase * * : [histone H3]-trimethyl-LL-lysine⁴ demethylase * * : [histone H3]-trimethyl-L-lysine²⁷ demethylase * * : [histone H3]-trimethyl-L-lysine³⁷ demethylase * * : 7-deoxycylindrospermopsin hydroxylase * * : methylphosphonate hydroxylase * * : [2-(trimethylamino)ethyl]phosphonate dioxygenase * * : [protein]-arginine 3-hydroxylase * * : L-isoleucine 3¹-dioxygenase * * : 3¹-hydroxy-L-isoleucine 4-dioxygenase * * : L-glutamate 3(''R'')-hydroxylase * * : alkyl sulfatase *

EC 1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor

* : anthranilate 1,2-dioxygenase (deaminating, decarboxylating) * EC 1.14.12.2: Now anthranilate 3-monooxygenase (deaminating) * : benzene 1,2-dioxygenase * EC 1.14.12.4: , 3-hydroxy-2-methylpyridinecarboxylate monooxygenase * EC 1.14.12.5: Now , 5-pyridoxate monooxygenase * EC 1.14.12.6: Now , 2-hydroxycyclohexanone 2-monooxygenase * : phthalate 4,5-dioxygenase * : 4-sulfobenzoate 3,4-dioxygenase * : 4-chlorophenylacetate 3,4-dioxygenase * : benzoate 1,2-dioxygenase * : toluene dioxygenase * : naphthalene 1,2-dioxygenase * : 2-chlorobenzoate 1,2-dioxygenase, 2-halobenzoate 1,2-dioxygenase * : 2-aminobenzenesulfonate 2,3-dioxygenase * : terephthalate 1,2-dioxygenase * : 2-hydroxyquinoline 5,6-dioxygenase * : nitric oxide dioxygenase * : biphenyl 2,3-dioxygenase * : 3-phenylpropionate dioxygenase * EC 1.14.12.20: Now classified as , pheophorbide ''a'' oxygenase. * EC 1.14.12.21: Now , benzoyl-CoA 2,3-epoxidase * : carbazole 1,9a-dioxygenase * : nitroarene dioxygenase * * : 2,4-dinitrotoluene dioxygenase * * : ''p''-cumate 2,3-dioxygenase * * : chlorobenzene dioxygenase * : *No Wikipedia article

EC 1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

* : salicylate 1-monooxygenase * : 4-hydroxybenzoate 3-monooxygenase * EC 1.14.13.3: Now , 4-hydroxyphenylacetate 3-monooxygenase * : melilotate 3-monooxygenase * : imidazoleacetate 4-monooxygenase * : orcinol 2-monooxygenase * : phenol 2-monooxygenase * : dimethylaniline monooxygenase (N-oxide-forming), flavin-containing monooxygenase * : kynurenine 3-monooxygenase * : 2,6-dihydroxypyridine 3-monooxygenase * EC 1.14.13.11: Now , trans-cinnamate 4-monooxygenase * EC 1.14.13.12: Now , benzoate 4-monooxygenase * EC 1.14.13.13: Now classified as , calcidiol 1-monooxygenase * : trans-cinnamate 2-monooxygenase, ''trans''-cinnamate 2-monooxygenase * EC 1.14.13.15: Now , cholestanetriol 26-monooxygenase * : cyclopentanone monooxygenase * EC 1.14.13.17: Now , cholesterol 7α-monooxygenase * : 4-hydroxyphenylacetate 1-monooxygenase * : taxifolin 8-monooxygenase * : 2,4-dichlorophenol 6-monooxygenase * EC 1.14.13.21: Now , flavonoid 3′-monooxygenase * : cyclohexanone monooxygenase * : 3-hydroxybenzoate 4-monooxygenase * : 3-hydroxybenzoate 6-monooxygenase * : methane monooxygenase, methane monooxygenase (soluble) * EC 1.14.13.26: Now classified as , phosphatidylcholine 12-monooxygenase * : 4-aminobenzoate 1-monooxygenase * EC 1.14.13.28: Now , 3,9-dihydroxypterocarpan 6a-monooxygenase * : 4-nitrophenol 2-monooxygenase * EC 1.14.13.30: Now , leukotriene-B₄ 20-monooxygenase * : 2-nitrophenol 2-monooxygenase * : albendazole monooxygenase * : 4-hydroxybenzoate 3-monooxygenase (NAD(P)H) * : leukotriene-E4 20-monooxygenase, leukotriene-E₄ 20-monooxygenase * : anthranilate 3-monooxygenase (deaminating) * EC 1.14.13.36: Now , 5-''O''-(4-coumaroyl)-D-quinate 3′-monooxygenase * EC 1.14.13.37: Now , methyltetrahydroprotoberberine 14-monooxygenase * : anhydrotetracycline monooxygenase * : nitric-oxide synthase * : anthraniloyl-CoA monooxygenase * EC 1.14.13.41: Now , tyrosine ''N''-monooxygenase * EC 1.14.13.42: The activity is covered by , 4-hydroxyphenylacetaldehyde oxime monooxygenase * : questin monooxygenase * : 2-hydroxybiphenyl 3-monooxygenase * EC 1.14.13.45: Now , CMP-''N''-acetylneuraminate monooxygenase * : (-)-menthol monooxygenase * EC 1.14.13.47: Now , (S)-limonene 3-monooxygenase, (''S'')-limonene 3-monooxygenase * EC 1.14.13.48: Now classified as , (''S'')-limonene 6-monooxygenase * EC 1.14.13.49: Now classified as , ((S)-limonene 7-monooxygenase, ''S'')-limonene 7-monooxygenase * : pentachlorophenol monooxygenase * : 6-oxocineole dehydrogenase * EC 1.14.13.52: Now , isoflavone 3′-hydroxylase * EC 1.14.13.53: Now , 4′-methoxyisoflavone 2′-hydroxylase * : ketosteroid monooxygenase * EC 1.14.13.55: Now , protopine 6-monooxygenase * EC 1.14.13.56: Now , dihydrosanguinarine 10-monooxygenase * EC 1.14.13.57: Now , dihydrochelirubine 12-monooxygenase * : benzoyl-CoA 3-monooxygenase * : L-lysine 6-monooxygenase (NADPH), L-lysine ''N''⁶-monooxygenase (NADPH) * EC 1.14.13.60: Now included with , 25-hydroxycholesterol 7α-hydroxylase * : 2-hydroxyquinoline 8-monooxygenase * : 4-hydroxyquinoline 3-monooxygenase * : 3-hydroxyphenylacetate 6-hydroxylase * : 4-hydroxybenzoate 1-hydroxylase * EC 1.14.13.65: deleted * : 2-hydroxycyclohexanone 2-monooxygenase * EC 1.14.13.67: Now , quinine 3-monooxygenase * EC 1.14.13.68: Now , 4-hydroxyphenylacetaldehyde oxime monooxygenase * : alkene monooxygenase * EC 1.14.13.70: Now , sterol 14α-demethylase * EC 1.14.13.71: Now , ''N''-methylcoclaurine 3′-monooxygenase * EC 1.14.13.72: Now classified as , methylsterol monooxygenase * EC 1.14.13.73: Now , tabersonine 16-hydroxylase * EC 1.14.13.74: Now , 7-deoxyloganin 7-hydroxylase * EC 1.14.13.75: Now , vinorine hydroxylase * EC 1.14.13.76: Now , taxane 10β-hydroxylase * EC 1.14.13.77: Now , taxane 13α-hydroxylase * EC 1.14.13.78: Now , ''ent''-kaurene monooxygenase * EC 1.14.13.79: Now , ''ent''-kaurenoic acid oxidase * EC 1.14.13.80: Now classified as , (''R'')-limonene 6-monooxygenase * : magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase * : vanillate monooxygenase * : precorrin-3B synthase * : 4-hydroxyacetophenone monooxygenase * EC 1.14.13.85: Now , glyceollin synthase * EC 1.14.13.86: The activity is covered by , 2-hydroxyisoflavanone synthase * EC 1.14.13.87: Now , licodione synthase] * EC 1.14.13.88: Now , flavanoid 3,5-hydroxylase * EC 1.14.13.89: Now , isoflavone 2-hydroxylase * EC 1.14.13.90: Now , zeaxanthin epoxidase * EC 1.14.13.91: Now , deoxysarpagine hydroxylase * : phenylacetone monooxygenase * EC 1.14.13.93: Now , (+)-abscisic acid 8-hydroxylase * EC 1.14.13.94: Now , lithocholate 6β-hydroxylase * EC 1.14.13.95: Now included with , 5β-cholestane-3α,7α-diol 12α-hydroxylase * EC 1.14.13.96: Now , 5β-cholestane-3α,7α-diol 12α-hydroxylase * EC 1.14.13.97: Now , taurochenodeoxycholate 6α-hydroxylase * EC 1.14.13.98: Now , cholesterol 24-hydroxylase * EC 1.14.13.99: Now , 24-hydroxycholesterol 7α-hydroxylase * EC 1.14.13.100: Now classified as , 25/26-hydroxycholesterol 7α-hydroxylase * : senecionine N-oxygenase, senecionine ''N''-oxygenase * EC 1.14.13.102: Now , psoralen synthase * EC 1.14.13.103: Now , 8-dimethylallylnaringenin 2-hydroxylase * : Now , (+)-menthofuran synthase * : monocyclic monoterpene ketone monooxygenase * EC 1.14.13.106: now classified as , ''epi''-isozizaene 5-monooxygenase. * : limonene 1,2-monooxygenase * EC 1.14.13.108: Now , abieta-7,13-diene hydroxylase * EC 1.14.13.109: Now , abieta-7,13-dien-18-ol hydroxylase * EC 1.14.13.110: Now , geranylgeraniol 18-hydroxylase * : methanesulfonate monooxygenase * EC 1.14.13.112: Now , 3-epi-6-deoxocathasterone 23-monooxygenase * : FAD-dependent urate hydroxylase * : 6-hydroxynicotinate 3-monooxygenase * EC 1.14.13.115: Now , angelicin synthase * : Now , geranylhydroquinone 3-hydroxylase * EC 1.14.13.117: Now , isoleucine ''N''-monooxygenase * EC 1.14.13.118: Now , valine ''N''-monooxygenase * EC 1.14.13.119: Now , 5-epiaristolochene 1,3-dihydroxylase * EC 1.14.13.120: Now , costunolide synthase * EC 1.14.13.121: Now , premnaspirodiene oxygenase * : chlorophyllide-a oxygenase * EC 1.14.13.123: Now , germacrene A hydroxylase * EC 1.14.13.124: now classified as , phenylalanine ''N''-monooxygenase * EC 1.14.13.125: Now , tryptophan ''N''-monooxygenase * EC 1.14.13.126: Now , vitamin D₃ 24-hydroxylase * : 3-(3-hydroxyphenyl)propanoate hydroxylase * : 7-methylxanthine demethylase * EC 1.14.13.129: Now , β-carotene 3-hydroxylase * : pyrrole-2-carboxylate monooxygenase * : dimethyl-sulfide monooxygenase * EC 1.14.13.132: Now , squalene monooxygenase * EC 1.14.13.133: Now , pentalenene oxygenase * EC 1.14.13.134: Now , β-amyrin 11-oxidase * : 1-hydroxy-2-naphthoate hydroxylase * EC 1.14.13.136: Now , 2-hydroxyisoflavanone synthase * EC 1.14.13.137: Now , indole-2-monooxygenase * EC 1.14.13.138: Now , indolin-2-one monooxygenase * EC 1.14.13.139: Now , 3-hydroxyindolin-2-one monooxygenase * EC 1.14.13.140: Now , 2-hydroxy-1,4-benzoxazin-3-one monooxygenase. * EC 1.14.13.141: Now , cholest-4-en-3-one 26-monooxygenase [(25''S'')-3-oxocholest-4-en-26-oate forming] * EC 1.14.13.142: Now , 3-ketosteroid 9α-monooxygenase * EC 1.14.13.143: Now ''ent''-isokaurene C2/C3-hydroxylase * EC 1.14.13.144: Now , 9β-pimara-7,15-diene oxidase * EC 1.14.13.145: Now , ''ent''-cassa-12,15-diene 11-hydroxylase * : taxoid 14beta-hydroxylase, taxoid 14β-hydroxylase * : taxoid 7beta-hydroxylase, taxoid 7β-hydroxylase * : trimethylamine monooxygenase * : phenylacetyl-CoA 1,2-epoxidase * EC 1.14.13.150: Now , α-humulene 10-hydroxylase * EC 1.14.13.151: Now , linalool 8-monooxygenase * EC 1.14.13.152: Now , geraniol 8-hydroxylase * : (+)-sabinene 3-hydroxylase * : erythromycin 12 hydroxylase, erythromycin 12-hydroxylase * : alpha-pinene monooxygenase, α-pinene monooxygenase * EC 1.14.13.156: Now , 1,8-cineole 2-endo-monooxygenase * EC 1.14.13.157: Now , 1,8-cineole 2-exo-monooxygenase * EC 1.14.13.158: Now , amorpha-4,11-diene 12-monooxygenase * EC 1.14.13.159: Now , vitamin D 25-hydroxylase * : (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 1,5-monooxygenase * : (+)-camphor 6-exo-hydroxylase * EC 1.14.13.162: Now , 2,5-diketocamphane 1,2-monooxygenase * : 6-hydroxy-3-succinoylpyridine 3-monooxygenase * EC 1.14.13.164: withdrawn: see , carotenoid isomerooxygenase * EC 1.14.13.165: Now classified as , nitric-oxide synthase (flavodoxin) * : 4-nitrocatechol 4-monooxygenase : Most of the entries from here on have no Wikipedia articles * : 4-nitrophenol 4-monooxygenase * : indole-3-pyruvate monooxygenase * EC 1.14.13.169: Now , sphingolipid C4-monooxygenase * : pentalenolactone D synthase * : neopentalenolactone D synthase * : salicylate 5-hydroxylase * EC 1.14.13.173: Now , 11-oxo-β-amyrin 30-oxidase * EC 1.14.13.174: Now , averantin hydroxylase * EC 1.14.13.175: Now , aflatoxin B synthase * EC 1.14.13.176: Now , tryprostatin B 6-hydroxylase * EC 1.14.13.177: Now , fumitremorgin C monooxygenase * : methylxanthine ''N''¹-demethylase * : methylxanthine ''N''³-demethylase * : aklavinone 12-hydroxylase * : 13-deoxydaunorubicin hydroxylase * : 2-heptyl-3-hydroxy-4(1''H'')-quinolone synthase * EC 1.14.13.183: Now , dammarenediol 12-hydroxylase * EC 1.14.13.184: Now , protopanaxadiol 6-hydroxylase * EC 1.14.13.185: Now , pikromycin synthase * EC 1.14.13.186: Now , 20-oxo-5-''O''-mycaminosyltylactone 23-monooxygenase * : L-evernosamine nitrososynthase * EC 1.14.13.188: Now , 6-deoxyerythronolide B hydroxylase * : 5-methyl-1-naphthoate 3-hydroxylase * EC 1.14.13.190: Now , ferruginol synthase * EC 1.14.13.191: Now , ''ent''-sandaracopimaradiene 3-hydroxylase * EC 1.14.13.192: Now , oryzalexin E synthase * EC 1.14.13.193: Now , oryzalexin D synthase * EC 1.14.13.194: Now , phylloquinone ω-hydroxylase * : L-ornithine ''N''⁵-monooxygenase (NADPH) * : L-ornithine ''N''⁵-monooxygenase [NAD(P)H] * EC 1.14.13.197: Now , dihydromonacolin L hydroxylase * EC 1.14.13.198: Now , monacolin L hydroxylase * EC 1.14.13.199: Now , docosahexaenoic acid ω-hydroxylase * : tetracenomycin A2 monooxygenase-dioxygenase * EC 1.14.13.201: Now , β-amyrin 28-monooxygenase * EC 1.14.13.202: Now , methyl farnesoate epoxidase * EC 1.14.13.203: Now , farnesoate epoxidase * EC 1.14.13.204: Now , long-chain acyl-CoA ω-monooxygenase * EC 1.14.13.205: Now , long-chain fatty acid ω-monooxygenase * EC 1.14.13.206: Now , laurate 7-monooxygenase * EC 1.14.13.207: Now , ipsdienol synthase * : benzoyl-CoA 2,3-epoxidase * : salicyloyl-CoA 5-hydroxylase * : 4-methyl-5-nitrocatechol 5-monooxygenase * : rifampicin monooxygenase * : 1,3,7-trimethyluric acid 5-monooxygenase * EC 1.14.13.213: Now , bursehernin 5-monooxygenase * EC 1.14.13.214: Now , (–)-4′-demethyl-deoxypodophyllotoxin 4-hydroxylase * : protoasukamycin 4-monooxygenase * : asperlicin C monooxygenase * : protodeoxyviolaceinate monooxygenase * : 5-methylphenazine-1-carboxylate 1-monooxygenase * : resorcinol 4-hydroxylase (NADPH) * : resorcinol 4-hydroxylase (NADH) * EC 1.14.13.221: Now , cholest-4-en-3-one 26-monooxygenase [(25''R'')-3-oxocholest-4-en-26-oate forming] * : aurachin C monooxygenase/isomerase * : 3-hydroxy-4-methylanthranilyl-[aryl-carrier protein] 5-monooxygenase * : violacein synthase * : F-actin monooxygenase * : acetone monooxygenase (methyl acetate-forming) * : propane 2-monooxygenase * : jasmonic acid 12-hydroxylase * : ''tert''-butyl alcohol monooxygenase * : butane monooxygenase (soluble) * : tetracycline 11a-monooxygenase * : 6-methylpretetramide 4-monooxygenase * : 4-hydroxy-6-methylpretetramide 12a-monooxygenase * : 5a,11a-dehydrotetracycline 5-monooxygenase * : indole-3-acetate monooxygenase * : toluene 4-monooxygenase * : aliphatic glucosinolate ''S''-oxygenase * : dimethylamine monooxygenase * : carnitine monooxygenase * : 2-polyprenylphenol 6-hydroxylase * : 5-pyridoxate monooxygenase * : 3-hydroxy-2-methylpyridine-5-carboxylate monooxygenase * : toluene 2-monooxygenase * : phenol 2-monooxygenase (NADH) * : assimilatory dimethylsulfide ''S''-monooxygenase * : 4β-methylsterol monooxygenase * : stachydrine ''N''-demethylase

EC 1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

* : unspecific monooxygenase * EC 1.14.14.2: Now included with unspecific monooxygenase * : alkanal monooxygenase (FMN-linked) * EC 1.14.14.4: identical to , choline monooxygenase. * : alkanesulfonate monooxygenase * EC 1.14.14.6: Now , methanesulfonate monooxygenase * EC 1.14.14.7: transferred to , tryptophan 7-halogenase * : anthranilate 3-monooxygenase (FAD) * : 4-hydroxyphenylacetate 3-monooxygenase * : nitrilotriacetate monooxygenase * : styrene monooxygenase * : 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase * : 4-(gamma-L-glutamylamino)butanoyl-(BtrI acyl-carrier protein) monooxygenase, 4-(γ-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein] monooxygenase : Most of the entries from here on have no Wikipedia articles * : aromatase * : (3''S'')-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[peptidyl-carrier protein SgcC2] monooxygenase * : steroid 21-monooxygenase * : squalene monooxygenase * : heme oxygenase (biliverdin-producing) * : steroid 17α-monooxygenase * : phenol 2-monooxygenase (FADH₂) * : dibenzothiophene monooxygenase * : dibenzothiophene sulfone monooxygenase * : cholesterol 7α-monooxygenase * : vitamin D 25-hydroxylase * : cholesterol 24-hydroxylase * : 24-hydroxycholesterol 7α-hydroxylase * : resorcinol 4-hydroxylase (FADH₂) * : long-chain alkane monooxygenase * : 25/26-hydroxycholesterol 7α-hydroxylase * : isobutylamine ''N''-monooxygenase * : ipsdienol synthase * : 17α-hydroxyprogesterone deacetylase * : ethylenediaminetetraacetate monooxygenase * : methanesulfonate monooxygenase (FMNH₂) * : dimethylsulfone monooxygenase * : tyrosine ''N''-monooxygenase * : 4-hydroxyphenylacetaldehyde oxime monooxygenase * : valine ''N''-monooxygenase * : isoleucine ''N''-monooxygenase * : phenylalanine ''N''-monooxygenase * : (''E'')-2-methylbutanal oxime monooxygenase * : homomethionine ''N''-monooxygenase * : (methylsulfanyl)alkanaldoxime ''N''-monooxygenase * : phenylacetaldehyde oxime monooxygenase * : aromatic aldoxime ''N''-monooxygenase * : pimeloyl-[acyl-carrier protein] synthase * : nitric-oxide synthase (flavodoxin) * : jasmonoyl-L-amino acid 12-hydroxylase * : 12-hydroxyjasmonoyl-L-amino acid 12-hydroxylase * : tabersonine 3-oxygenase * : (''S'')-limonene 6-monooxygenase * : (''S'')-limonene 7-monooxygenase * : (''R'')-limonene 6-monooxygenase * : phenylacetate 2-hydroxylase * : quinine 3-monooxygenase * : 1,8-cineole 2-exo-monooxygenase * : taurochenodeoxycholate 6α-hydroxylase * : trimethyltridecatetraene synthase * : dimethylnonatriene synthase * : ferruginol monooxygenase * : carnosic acid synthase * : salviol synthase * : β-amyrin 16β-monooxygenase * : β-amyrin 6β-monooxygenase * : sugiol synthase * : marmesin synthase * : 11-hydroxysugiol 20-monooxygenase * : ''syn''-pimaradiene 3-monooxygenase * : ''ent''-cassadiene hydroxylase * : ''ent''-sandaracopimaradiene 3-hydroxylase * : cucurbitadienol 11-hydroxylase * : drimenol monooxygenase * : albendazole monooxygenase (sulfoxide-forming) * : albendazole monooxygenase (hydroxylating) * : fenbendazole monooxygenase (4′-hydroxylating) * : ''ent''-isokaurene C2/C3-hydroxylase * : phenylacetonitrile α-monooxygenase * : phylloquinone ω-hydroxylase * : docosahexaenoic acid ω-hydroxylase * : long-chain fatty acid ω-monooxygenase * : flavanoid 3′,5′-hydroxylase * : flavonoid 3′-monooxygenase * : geraniol 8-hydroxylase * : linalool 8-monooxygenase * : 7-deoxyloganate 7-hydroxylase * : ''ent''-kaurene monooxygenase * : 2-hydroxyisoflavanone synthase * : isoflavone 3′-hydroxylase * : 4′-methoxyisoflavone 2′-hydroxylase * : isoflavone 2′-hydroxylase * : ''trans''-cinnamate 4-monooxygenase * : benzoate 4-monooxygenase * : 3,9-dihydroxypterocarpan 6a-monooxygenase * : leukotriene-B4 20-monooxygenase * : germacrene A hydroxylase * : 5-''O''-(4-coumaroyl)-D-quinate 3′-monooxygenase * : methyltetrahydroprotoberberine 14-monooxygenase * : protopine 6-monooxygenase * : (''S'')-limonene 3-monooxygenase * : dihydrosanguinarine 10-monooxygenase * : dihydrochelirubine 12-monooxygenase * : ''N''-methylcoclaurine 3′-monooxygenase * : tabersonine 16-hydroxylase * : vinorine hydroxylase * : taxane 10β-hydroxylase * : taxane 13α-hydroxylase * : ent-kaurenoic acid monooxygenase * : 2,5-diketocamphane 1,2-monooxygenase * : 3-hydroxyindolin-2-one monooxygenase * : 2-hydroxy-1,4-benzoxazin-3-one monooxygenase * : 9β-pimara-7,15-diene oxidase * : ent-cassa-12,15-diene 11-hydroxylase * : α-humulene 10-hydroxylase * : amorpha-4,11-diene 12-monooxygenase * : 11-oxo-β-amyrin 30-oxidase * : averantin hydroxylase * : aflatoxin B synthase * : tryprostatin B 6-hydroxylase * : fumitremorgin C monooxygenase * : dammarenediol 12-hydroxylase * : protopanaxadiol 6-hydroxylase * : oryzalexin E synthase * : oryzalexin D synthase * : dihydromonacolin L hydroxylase * : monacolin L hydroxylase * : β-amyrin 28-monooxygenase * : methyl farnesoate epoxidase * : farnesoate epoxidase * : long-chain acyl-CoA ω-monooxygenase * : laurate 7-monooxygenase * : bursehernin 5′-monooxygenase * : (–)-4′-demethyl-deoxypodophyllotoxin 4-hydroxylase * : 1,8-cineole 2-endo-monooxygenase * : β-amyrin 24-hydroxylase * : glyceollin synthase * : deoxysarpagine hydroxylase * : (+)-abscisic acid 8′-hydroxylase * : lithocholate 6β-hydroxylase * : 5β-cholestane-3α,7α-diol 12α-hydroxylase * EC 1.14.14.140: Now included with , flavanone 2-hydroxylase * : psoralen synthase * : 8-dimethylallylnaringenin 2′-hydroxylase * : (+)-menthofuran synthase * : abieta-7,13-diene hydroxylase * : abieta-7,13-dien-18-ol hydroxylase * : geranylgeraniol 18-hydroxylase * : 3-epi-6-deoxocathasterone 23-monooxygenase * : angelicin synthase * : 5-epiaristolochene 1,3-dihydroxylase * : costunolide synthase * : premnaspirodiene oxygenase * : β-amyrin 11-oxidase * : indole-2-monooxygenase * : sterol 14α-demethylase * : 3,6-diketocamphane 1,2-monooxygenase * : tryptophan ''N''-monooxygenase * : indolin-2-one monooxygenase * : carotenoid ε hydroxylase * : dolabradiene monooxygenase * : zealexin A1 synthase * : nepetalactol monooxygenase * : flavanone 2-hydroxylase * : (''S'')-1-hydroxy-N-methylcanadine 13-hydroxylase * : fraxetin 5-hydroxylase * : indole-3-carbonyl nitrile 4-hydroxylase * : (''S'')-N-methylcanadine 1-hydroxylase * : (13''S'',14''R'')-13-''O''-acetyl-1-hydroxy-''N''-methylcanadine 8-hydroxylase * : germacrene A acid 8β-hydroxylase * : eupatolide synthase * : 8-''epi''-inunolide synthase * : β-amyrin 16α-hydroxylase * : 3,5,6-trichloropyridin-2-ol monooxygenase * : 2,4,6-trichlorophenol monooxygenase * : geranylhydroquinone 3′′-hydroxylase * : ferruginol synthase * : taxadiene 5α-hydroxylase * : ultra-long-chain fatty acid ω-hydroxylase

EC 1.14.15 With reduced iron–sulfur protein as one donor, and incorporation of one atom of oxygen

* : camphor 5-monooxygenase * EC 1.14.15.2: Now , 2,5-diketocamphane 1,2-monooxygenase. * : alkane 1-monooxygenase * : steroid 11b-monooxygenase, steroid 11β-monooxygenase * : corticosterone 18-monooxygenase * : cholesterol monooxygenase (side-chain-cleaving) * : choline monooxygenase * : steroid 15beta-monooxygenase, steroid 15β-monooxygenase * : spheroidene monooxygenase * : (+)-camphor 6-endo-hydroxylase, (+)-camphor 6-''endo''-hydroxylase * : pentalenic acid synthase * EC 1.14.15.12 : pimeloyl-[acyl-carrier protein] synthase. Now , pimeloyl-[acyl-carrier protein] synthase : Most entries from here on have no Wikipedia articles * : pulcherriminic acid synthase * : methyl-branched lipid ω-hydroxylase * : cholestanetriol 26-monooxygenase * : vitamin D₃ 24-hydroxylase * : pheophorbide a oxygenase * : calcidiol 1-monooxygenase * : C-19 steroid 1α-hydroxylase * : heme oxygenase (biliverdin-producing, ferredoxin) * : zeaxanthin epoxidase * : vitamin D 1,25-hydroxylase * : chloroacetanilide ''N''-alkylformylase * : β-carotene 3-hydroxylase * : ''p''-cymene methyl-monooxygenase * : toluene methyl-monooxygenase * : β-dihydromenaquinone-9 ω-hydroxylase * : cholest-4-en-3-one 26-monooxygenase [(25''R'')-3-oxocholest-4-en-26-oate forming] * : cholest-4-en-3-one 26-monooxygenase [(25''S'')-3-oxocholest-4-en-26-oate forming] * : 3-ketosteroid 9α-monooxygenase * : 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase * : pentalenene oxygenase * : pikromycin synthase * : 20-oxo-5-''O''-mycaminosyltylactone 23-monooxygenase * : 6-deoxyerythronolide B hydroxylase * : sterol 14α-demethylase (ferredoxin) * : luteothin monooxygenase * : ''N,N''-dimethyl phenylurea ''N''-demethylase * : ''epi''-isozizaene 5-monooxygenase

EC 1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor

* : phenylalanine 4-monooxygenase * : tyrosine 3-monooxygenase * EC 1.14.16.3: withdrawn owing to insufficient evidence (anthranilate 3-monooxygenase) * : tryptophan 5-monooxygenase * : glyceryl-ether monooxygenase, alkylglycerol monooxygenase * : mandelate 4-monooxygenase * : phenylalanine 3-monooxygenase

EC 1.14.17 With reduced ascorbate as one donor, and incorporation of one atom of oxygen into the other donor

* : dopamine b-monooxygenase, dopamine β-monooxygenase * EC , 1.14.17.2: deleted, now included with monophenol monooxygenase * : peptidylglycine monooxygenase * : aminocyclopropanecarboxylate oxidase

EC 1.14.18 With another compound as one donor, and incorporation of one atom of oxygen into the other donor

* : monophenol monooxygenase, tyrosinase * : CMP-N-acetylneuraminate monooxygenase, CMP-''N''-acetylneuraminate monooxygenase * : methane monooxygenase (particulate) * : phosphatidylcholine 12-monooxygenase * * : sphingolipid C4-monooxygenase * * : 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase * * : dihydroceramide fatty acyl 2-hydroxylase * * EC 1.14.18.8: Now included with , 5β-cholestane-3α,7α-diol 12α-hydroxylase * : 4α-methylsterol monooxygenase * * : plant 4,4-dimethylsterol C-4α-methyl-monooxygenase * * : plant 4α-monomethylsterol monooxygenase * * : 2-hydroxy fatty acid dioxygenase * : *No Wikipedia article

EC 1.14.19 With oxidation of a pair of donors resulting in the reduction of O₂ to two molecules of water

* : stearoyl-CoA 9-desaturase * : acyl-(acyl-carrier-protein) desaturase, stearoyl- cyl-carrier-protein9-desaturase * : linoleoyl-CoA desaturase * : Delta8-fatty-acid desaturase, acyl-lipid (11-3)-desaturase * : Delta11-fatty-acid desaturase, acyl-CoA 11-(''Z'')-desaturase * : Delta12-fatty-acid desaturase, acyl-CoA (9+3)-desaturase * EC 1.14.19.7: Now , (''S'')-2-hydroxypropylphosphonic acid epoxidase : Most of the entries from here on have no Wikipedia articles * : pentalenolactone synthase * : tryptophan 7-halogenase * : icosanoyl-CoA 5-desaturase * : acyl- cyl-carrier-protein4-desaturase * : acyl-lipid ω-(9-4) desaturase * : acyl-CoA 15-desaturase * : linoleoyl-lipid Δ⁹ conjugase * : (11Z)-hexadec-11-enoyl-CoA conjugase * : linoleoyl-lipid Δ¹² conjugase (11''E'',13''Z''-forming) * : sphingolipid 4-desaturase * : sphingolipid 8-(''E'')-desaturase * : sphingolipid 10-desaturase * : Δ⁷-sterol 5(6)-desaturase * : cholesterol 7-desaturase * : acyl-lipid ω-6 desaturase (cytochrome ''b''₅) * : acyl-lipid (n+3)-(''Z'')-desaturase (ferredoxin) * : acyl-CoA 11-(''E'')-desaturase * : acyl-lipid ω-3 desaturase (cytochrome ''b''₅) * : acyl- cyl-carrier-protein6-desaturase * : ''sn''-2 palmitoyl-lipid 9-desaturase * : ''sn''-1 stearoyl-lipid 9-desaturase * : sphingolipid 8-(''E/Z'')-desaturase * : acyl-lipid (8-3)-desaturase * : acyl-lipid (7-3)-desaturase * : palmitoyl-CoA 14-(''E/Z'')-desaturase * : Δ¹² acyl-lipid conjugase (11''E'',13''E''-forming) * : acyl-lipid (9+3)-(''E'')-desaturase * : ''sn''-2 acyl-lipid ω-3 desaturase (ferredoxin) * : ''sn''-1 acyl-lipid ω-3 desaturase (ferredoxin) * : acyl-CoA 5-desaturase * : acyl-lipid Δ⁶-acetylenase * : acyl-lipid Δ¹²-acetylenase * : hex-5-enoyl-[acyl-carrier protein] acetylenase * : sterol 22-desaturase * : palmitoyl-[glycerolipid] 7-desaturase * : palmitoyl-[glycerolipid] 3-(''E'')-desaturase * : acyl-CoA (8-3)-desaturase * : ''sn''-1 oleoyl-lipid 12-desaturase * : ''sn''-1 linoleoyl-lipid 6-desaturase * : acyl-lipid (9-3)-desaturase * : ''tert''-amyl alcohol desaturase * : tetracycline 7-halogenase * : noroxomaritidine synthase * : (''S'')-corytuberine synthase * : camalexin synthase * : ''all-trans''-retinol 3,4-desaturase * : 1,2-dehydroreticuline synthase * : 4-hydroxybenzoate brominase (decarboxylating) * : 1''H''-pyrrole-2-carbonyl- eptidyl-carrier proteinchlorinase * : 1''H''-pyrrole-2-carbonyl- eptidyl-carrier proteinbrominase * : tryptophan 5-halogenase * : tryptophan 6-halogenase * : 7-chloro-L-tryptophan 6-halogenase * : dihydrorhizobitoxine desaturase * : secologanin synthase * : pseudobaptigenin synthase * : (''S'')-stylopine synthase * : (''S'')-cheilanthifoline synthase * : berbamunine synthase * : salutaridine synthase * : (''S'')-canadine synthase * : biflaviolin synthase * : mycocyclosin synthase * : fumitremorgin C synthase * : (–)-pluviatolide synthase * : (''S'')-nandinine synthase * : (+)-piperitol/(+)-sesamin synthase * : very-long-chain acyl-lipid ω-9 desaturase * : flavone synthase II * : plasmanylethanolamine desaturase * : decanoyl-[acyl-carrier protein] acetylenase

EC 1.14.20 With 2-oxoglutarate as one donor, and the other dehydrogenated

* : deacetoxycephalosporin-C synthase * EC 1.14.20.2: Now , 2,4-dihydroxy-1,4-benzoxazin-3-one-glucoside dioxygenase * : (5''R'')-carbapenem-3-carboxylate synthase * * : anthocyanidin synthase * * : flavone synthase I * * : flavonol synthase * * : 2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming) * * : (–)-deoxypodophyllotoxin synthase * * : L-tyrosine isonitrile desaturase * * : L-tyrosine isonitrile desaturase/decarboxylase * * : 3-[(''Z'')-2-isocyanoethenyl]-1''H''-indole synthase * * : 3-[(''E'')-2-isocyanoethenyl]-1''H''-indole synthase * * : 6β-hydroxyhyoscyamine epoxidase * * : hapalindole-type alkaloid chlorinase * * : L-threonyl-[L-threonyl-carrier protein] 4-chlorinase * : *No Wikipedia article

EC 1.14.21 With NADH or NADPH as one donor, and the other dehydrogenated

* EC 1.14.21.1: Now , (''S'')-stylopine synthase * EC 1.14.21.2: Now , (''S'')-cheilanthifoline synthase * EC 1.14.21.3: Now , berbamunine synthase * EC 1.14.21.4: Now , salutaridine synthase * EC 1.14.21.5: Now , (''S'')-canadine synthase * EC 1.14.21.6: Now , Δ⁷-sterol 5(6)-desaturase * EC 1.14.21.7: Now , biflaviolin synthase * EC 1.14.21.8: Now , pseudobaptigenin synthase * EC 1.14.21.9: Now , mycocyclosin synthase * * EC 1.14.21.10: Now , fumitremorgin C synthase * * EC 1.14.21.11: Now , (–)-pluviatolide synthase * * EC 1.14.21.12: Now , (''S'')-nandinine synthase * : *No Wikipedia article

EC 1.14.99 Miscellaneous

* : prostaglandin-endoperoxide synthase * : kynurenine 7,8-hydroxylase * EC 1.14.99.3: Now , heme oxygenase (biliverdin-producing) * : progesterone monooxygenase * EC 1.14.99.5: Now , stearoyl-CoA 9-desaturase * EC 1.14.99.6: Now , acyl- cyl-carrier-proteindesaturase * EC 1.14.99.7: Transferred to , squalene monooxygenase * EC 1.14.99.8: Now included with unspecific monooxygenase * EC 1.14.99.9: Now classified as , steroid 17α-monooxygenase * EC 1.14.99.10: Now , steroid 21-monooxygenase * : estradiol 6b-monooxygenase, estradiol 6β-monooxygenase * : 4-androstene-3,17-dione monooxygenase * EC 1.14.99.13: Now , 3-hydroxybenzoate 4-monooxygenase * : progesterone 11a-monooxygenase, progesterone 11α-monooxygenase * : 4-methoxybenzoate monooxygenase (O-demethylating), 4-methoxybenzoate monooxygenase (''O''-demethylating) * EC 1.14.99.16: Now , methylsterol monooxygenase * EC 1.14.99.17: Now , glyceryl-ether monooxygenase * EC 1.14.99.18: deleted * EC 1.14.99.19: Now classified as , plasmanylethanolamine desaturase * : phylloquinone monooxygenase (2,3-epoxidizing) * : Latia-luciferin monooxygenase (demethylating), ''Latia''-luciferin monooxygenase (demethylating) * : ecdysone 20-monooxygenase * : 3-hydroxybenzoate 2-monooxygenase * : steroid 9a-monooxygenase, steroid 9α-monooxygenase * : Now , linoleoyl-CoA desaturase * : 2-hydroxypyridine 5-monooxygenase * EC 1.14.99.27: Now classified as , juglone 3-monooxygenase * EC 1.14.99.28: Now , linalool 8-monooxygenase * : deoxyhypusine monooxygenase * EC 1.14.99.30: Now , 9,9′-''dicis''-ζ-carotene desaturase. * EC 1.14.99.31: Now classified as , myristoyl-CoA 11-(''E'') desaturase * EC 1.14.99.32: Now classified as , acyl-CoA 11-(''Z'')-desaturase * EC 1.14.99.33: Now , acyl-lipid Δ¹²-acetylenase * : monoprenyl isoflavone epoxidase * : thiophene-2-carbonyl-CoA monooxygenase * EC 1.14.99.36: Now classified as , β-carotene 15,15′-dioxygenase * EC 1.14.99.37: Now , taxadiene 5α-hydroxylase * : cholesterol 25-hydroxylase * : ammonia monooxygenase * EC 1.14.99.40: Now , 5,6-dimethylbenzimidazole synthase * EC 1.14.99.41: Now , ''all-trans''-8′-apo-β-carotenal 15,15′-oxygenase * EC 1.14.99.42: Now , crocetin dialdehyde synthase * EC 1.14.99.43: Now , β-amyrin 24-hydroxylase * : diapolycopene oxygenase * EC 1.14.99.45: Now , carotene ε-monooxygenase * : pyrimidine oxygenase * : (+)-larreatricin hydroxylase : Most of the entries from here on have no Wikipedia article * : heme oxygenase (staphylobilin-producing) * EC 1.14.99.49: Now , 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase * : γ-glutamyl hercynylcysteine ''S''-oxide synthase * : hercynylcysteine ''S''-oxide synthase * : L-cysteinyl-L-histidinylsulfoxide synthase * : lytic chitin monooxygenase * : lytic cellulose monooxygenase (C1-hydroxylating) * : lytic starch monooxygenase * : lytic cellulose monooxygenase (C4-dehydrogenating) * : heme oxygenase (mycobilin-producing) * : heme oxygenase (biliverdin-IX-β and δ-forming) * : tryptamine 4-monooxygenase * : 3-demethoxyubiquinol 3-hydroxylase * : cyclooctat-9-en-7-ol 5-monooxygenase * : cyclooctatin synthase * : β-carotene 4-ketolase * : zeaxanthin 4-ketolase * : 4-amino-L-phenylalanyl-[CmlP-peptidyl-carrier-protein] 3-hydroxylase * : [histone H3]-''N''⁶,''N''⁶-dimethyl-L-lysine⁴ FAD-dependent demethylase * : α-''N''-dichloroacetyl-p-aminophenylserinol ''N''-oxygenase * : 4-aminobenzoate ''N''-oxygenase * : tRNA 2-(methylsulfanyl)-''N''⁶-isopentenyladenosine³⁷ hydroxylase

EC 1.15 Acting on superoxide as acceptor

EC 1.15.1

* : superoxide dismutase * : superoxide reductase

EC 1.16 Oxidizing metal ions

EC 1.16.1 With NAD⁺ or NADP⁺ as acceptor

* : mercury(II) reductase * : diferric-transferrin reductase * EC 1.16.1.3: deleted since no specific enzyme catalysing this activity has been identified * : cob(II)alamin reductase * EC 1.16.1.5: deleted since the enzyme the entry was based on was later shown to be , pyruvate dehydrogenase (NADP⁺). * : cyanocobalamin reductase (cyanide-eliminating) * : ferric-chelate reductase * : (methionine synthase) reductase, [methionine synthase] reductase * : ferric-chelate reductase (NADPH) * : ferric-chelate reductase AD(P)H* : *No Wikipedia article

EC 1.16.3 With oxygen as acceptor

* : ferroxidase * : bacterial non-heme ferritin * * : manganese oxidase * : *No Wikipedia article

EC 1.16.5 With a quinone or similar compound as acceptor

* EC 1.16.5.1: Now , ascorbate ferrireductase (transmembrane)

EC 1.16.8 With a flavin as acceptor

* EC 1.16.8.1: activity now known to be catalyzed by , corrinoid adenosyltransferase

EC 1.16.9 With a copper protein as acceptor

* : iron:rusticyanin reductase

EC 1.16.98 With other, known, physiological acceptors

* EC 1.16.98.1: Now iron:rusticyanin reductase

EC 1.16.99 With unknown physiological acceptors

* : [Co(II) methylated amine-specific corrinoid protein] reductase

EC 1.17 Acting on CH or CH₂ groups

EC 1.17.1 With NAD or NADP as acceptor

* : CDP-4-dehydro-6-deoxyglucose reductase * EC 1.17.1.2: now classified as , 4-hydroxy-3-methylbut-2-enyl diphosphate reductase * : leucoanthocyanidin reductase * : xanthine dehydrogenase * : nicotinate dehydrogenase * EC 1.17.1.6: Now , bile-acid 7α-dehydroxylase. It is now known that FAD is the acceptor and not NAD⁺ as was thought previously * EC 1.17.1.7: Now , 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase * : 4-hydroxy-tetrahydrodipicolinate reductase * * : formate dehydrogenase * * : formate dehydrogenase (NADP⁺) * * : formate dehydrogenase (NAD⁺, ferredoxin) * : *No Wikipedia article

EC 1.17.2 With a cytochrome as acceptor

* : nicotinate dehydrogenase (cytochrome) * : lupanine 17-hydroxylase (cytochrome c) * : formate dehydrogenase (cytochrome-c-553) * : *No Wikipedia article

EC 1.17.3 With oxygen as acceptor

* : pteridine oxidase * : xanthine oxidase * : 6-hydroxynicotinate dehydrogenase * : juglone 3-hydroxylase * : *No Wikipedia article

EC 1.17.4 With a disulfide as acceptor

* : ribonucleoside-diphosphate reductase * : ribonucleoside-triphosphate reductase, ribonucleoside-triphosphate reductase (thioredoxin) * EC 1.17.4.3: transferred to , (''E'')-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase. * : vitamin-K-epoxide reductase (warfarin-sensitive) * * : vitamin-K-epoxide reductase (warfarin-insensitive) * : *No Wikipedia article

EC 1.17.5 With a quinone or similar compound as acceptor

* : phenylacetyl-CoA dehydrogenase * : caffeine dehydrogenase * : formate dehydrogenase-N * : *No Wikipedia article

EC 1.17.7 With an iron–sulfur protein as acceptor

* : 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, (''E'')-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin) * : 7-hydroxymethyl chlorophyll a reductase * : (''E'')-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin) * * : 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase * : *No Wikipedia article

EC 1.17.98 With other, known, physiological acceptors

* EC 1.17.98.1: bile-acid 7α-dehydroxylase. Now known to be catalyzed by multiple enzymes. * : bacteriochlorophyllide ''c'' C-7¹-hydroxylase * * : formate dehydrogenase (coenzyme F₄₂₀) * * : formate dehydrogenase (hydrogenase) * : *No Wikipedia article

EC 1.17.99 With unknown physiological acceptors

: No Wikipedia article for any of these * EC 1.17.99.1: Now EC 1.17.9.1, 4-methylphenol dehydrogenase (hydroxylating) * : ethylbenzene hydroxylase * : 3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA 24-hydroxylase * : uracil/thymine dehydrogenase * EC 1.17.99.5: Now classified as EC 1.17.98.1, bile-acid 7α-dehydroxylase * : epoxyqueuosine reductase * EC 1.17.99.7: Now classified as EC 1.17.98.4, formate dehydrogenase (hydrogenase) * : limonene dehydrogenase * : heme ''a'' synthase * : steroid C-25 hydroxylase * : 3-oxo-Δ¹-steroid hydratase/dehydrogenase

EC 1.18 Acting on iron–sulfur proteins as donors

EC 1.18.1 With NAD⁺ or NADP⁺ as acceptor

* : rubredoxin—NAD+ reductase, rubredoxin—NAD⁺ reductase * : ferredoxin—NADP+ reductase, ferredoxin—NADP⁺ reductase * : ferredoxin—NAD+ reductase, ferredoxin—NAD⁺ reductase * : rubredoxin—NAD(P)+ reductase, rubredoxin—NAD(P)⁺ reductase * : Putidaredoxin—NAD+ reductase, Putidaredoxin—NAD⁺ reductase * : adrenodoxin-NADP+ reductase, adrenodoxin-NADP⁺ reductase * : ferredoxin—NAD(P)⁺ reductase (naphthalene dioxygenase ferredoxin-specific) * EC 1.18.1.8: Now , ferredoxin—NAD⁺ oxidoreductase (Na⁺-transporting)

EC 1.18.2 With dinitrogen as acceptor (deleted sub-subclass)

* EC 1.18.2.1: now , nitrogenase

EC 1.18.3 With H⁺ as acceptor (deleted sub-subclass)

* EC 1.18.3.1: Now , ferredoxin hydrogenase

EC 1.18.6 With dinitrogen as acceptor

* : nitrogenase * : vanadium-dependent nitrogenase * : *No Wikipedia article

EC 1.18.96 With other, known, acceptors (deleted sub-subclass)

* EC 1.18.96.1: Now , superoxide reductase

EC 1.18.99 With H⁺ as acceptor (deleted sub-subclass)

* EC 1.18.99.1: Now , ferredoxin hydrogenase

EC 1.19 Acting on reduced flavodoxin as donor

EC 1.19.1 With NAD⁺ or NADP⁺ as acceptor

* : flavodoxin—NADP⁺ reductase

EC 1.19.6 With dinitrogen as acceptor

* : nitrogenase (flavodoxin)

EC 1.20 Acting on phosphorus or arsenic in donors

EC 1.20.1 Acting on phosphorus or arsenic in donors, with NAD⁺ as acceptor

* : phosphonate dehydrogenase

EC 1.20.2 Acting on phosphorus or arsenic in donors, with NAD(P)⁺ as acceptor

* : arsenate reductase (cytochrome c), arsenate reductase (cytochrome ''c'')

EC 1.20.4 Acting on phosphorus or arsenic in donors, with disulfide as acceptor

* : arsenate reductase (glutaredoxin) * : methylarsonate reductase * : mycoredoxin * : arsenate reductase (thioredoxin) * : *No Wikipedia article

EC 1.20.9 With a copper protein as acceptor

* : arsenate reductase (azurin)

EC 1.20.98 With other, known acceptors

* EC 1.20.98.1: Now , arsenate reductase (azurin)

EC 1.20.99 With unknown physiological acceptors

* : arsenate reductase (donor)

EC 1.21 Catalysing the reaction X-H + Y-H = X-Y

EC 1.21.3 With oxygen as acceptor

* : isopenicillin-N synthase * : columbamine oxidase * : reticuline oxidase * : sulochrin oxidase ((+)-bisdechlorogeodin-forming) * : sulochrin oxidase ((-)-bisdechlorogeodin-forming) * : aureusidin synthase * : tetrahydrocannabinolic acid synthase * : cannabidiolic acid synthase * EC 1.21.3.9: now classified as , dichlorochromopyrrolate synthase

EC 1.21.4 With a disulfide as acceptor

* : D-proline reductase (dithiol), D-proline reductase (dithiol) * : glycine reductase * : sarcosine reductase * : betaine reductase * : tetrachlorohydroquinone reductive dehalogenase * : *No Wikipedia article

EC 1.21.98 With other, known, physiological acceptors

* : cyclic dehypoxanthinyl futalosine synthase * * : dichlorochromopyrrolate synthase * * : anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase * * : PqqA peptide cyclase * : *No Wikipedia article

EC 1.21.99 With unknown physiological acceptors

* : β-cyclopiazonate dehydrogenase * EC 1.21.99.2: Now classified as , cyclic dehypoxanthinyl futalosine synthase. * : thyroxine 5-deiodinase * * : thyroxine 5′-deiodinase * * : tetrachloroethene reductive dehalogenase * : *No Wikipedia article

EC 1.22 Acting on halogen in donors

EC 1.22.1 With NAD⁺ or NADP⁺ as acceptor

* EC 1.22.1.1: Now , iodotyrosine deiodinase

EC 1.23 Reducing C-O-C group as acceptor

EC 1.23.1 With NADH or NADPH as donor

* : (+)-pinoresinol reductase * * : (+)-lariciresinol reductase * * : (–)-pinoresinol reductase * * : (–)-lariciresinol reductase * : *No Wikipedia article

EC 1.97 Other oxidoreductases

EC 1.97.1 Sole sub-subclass for oxidoreductases that do not belong in the other subclasses

* : chlorate reductase * : pyrogallol hydroxytransferase * EC 1.97.1.3: Now , sulfhydrogenase, since hydrogen is known to be the electron donor * : (formate-C-acetyltransferase)-activating enzyme, [formate-''C''-acetyltransferase]-activating enzyme * EC 1.97.1.5: Now , arsenate reductase (glutaredoxin * EC 1.97.1.6: Now , arsenate reductase (donor) * EC 1.97.1.7: Now , methylarsonate reductase * EC 1.97.1.8: Now , tetrachloroethene reductive dehalogenase * : selenate reductase * EC 1.97.1.10: Now thyroxine 5′-deiodinase * EC 1.97.1.11: Now thyroxine 5-deiodinase. * : photosystem I

EC 1.98 Enzymes using H₂ as reductant (deleted subclass)

EC 1.98.1.1: Now , ferredoxin hydrogenase

EC 1.99 Other enzymes using O₂ as oxidant

EC 1.99.1 Hydroxylases (now covered by EC 1.14)

* EC 1.99.1.1: deleted, Now , ferredoxin hydrogenase * EC 1.99.1.2: deleted, Now , phenylalanine 4-monooxygenase * EC 1.99.1.3: deleted, nicotinate 6-hydroxylase * EC 1.99.1.4: deleted, tryptophan 5-hydroxylase * EC 1.99.1.5: deleted, Now , kynurenine 3-monooxygenase * EC 1.99.1.6: deleted, steroid 11α-hydroxylase * EC 1.99.1.7: deleted, Now , steroid 11β-monooxygenase * EC 1.99.1.8: deleted, steroid 6β-hydroxylase * EC 1.99.1.9: deleted, Now , steroid 17α-monooxygenase * EC 1.99.1.10: deleted, steroid 19-hydroxylase * EC 1.99.1.11: deleted, Now , steroid 21-monooxygenase * EC 1.99.1.12: deleted, alkoxyaryl hydroxylase * EC 1.99.1.13: deleted, covered by (squalene monooxygenase) and by (lanosterol synthase) * EC 1.99.1.14: deleted, Now , 4-hydroxyphenylpyruvate dioxygenase

EC 1.99.2 Oxygenases (now covered by EC 1.13)

* EC 1.99.2.1: deleted, now , lipoxygenase * EC 1.99.2.2: deleted, now , catechol 1,2-dioxygenase * EC 1.99.2.3: deleted, now , protocatechuate 3,4-dioxygenase * EC 1.99.2.4: deleted, now , gentisate 1,2-dioxygenase * EC 1.99.2.5: deleted, now , homogentisate 1,2-dioxygenase * EC 1.99.2.6: deleted, now , inositol oxygenase

References

{{Reflist Biology-related lists, EC1 Hydrolases