Diagnosis (2019 TV series)
   HOME

TheInfoList



OR:

''Diagnosis'' is a 2019 documentary
streaming television Streaming television is the digital distribution of television content, such as TV shows, as streaming media delivered over the Internet. Streaming television stands in contrast to dedicated terrestrial television delivered by over-the-air aer ...
series. The series follows Dr.
Lisa Sanders Lisa Sanders (born July 24, 1956) is an American physician, medical author and journalist, and associate professor of internal medicine and education at Yale School of Medicine. In 2002, she began writing a column for ''The New York Times'' called ...
as she attempts to help patients with rare illnesses and searches for a diagnosis and cure using
wisdom of the crowd The wisdom of the crowd is the collective opinion of a diverse independent group of individuals rather than that of a single expert. This process, while not new to the Information Age, has been pushed into the mainstream spotlight by social infor ...
methods. The show is based on her column for ''
The New York Times Magazine ''The New York Times Magazine'' is an American Sunday magazine Supplement (publishing), supplement included with the Sunday edition of ''The New York Times''. It features articles longer than those typically in the newspaper and has attracted man ...
''. It was released on August 16, 2019, on
Netflix Netflix, Inc. is an American subscription video on-demand over-the-top streaming service and production company based in Los Gatos, California. Founded in 1997 by Reed Hastings and Marc Randolph in Scotts Valley, California, it offers a fil ...
.


Author

Lisa Sanders Lisa Sanders (born July 24, 1956) is an American physician, medical author and journalist, and associate professor of internal medicine and education at Yale School of Medicine. In 2002, she began writing a column for ''The New York Times'' called ...
was born on July 24, 1956 in South Carolina. Sanders grew up loving the idea of mystery and grew very fond of Arthur Conan Doyle’s fictional character, detective
Sherlock Holmes Sherlock Holmes () is a fictional detective created by British author Arthur Conan Doyle. Referring to himself as a " consulting detective" in the stories, Holmes is known for his proficiency with observation, deduction, forensic science and ...
. Sanders went to the
College of William & Mary The College of William & Mary (officially The College of William and Mary in Virginia, abbreviated as William & Mary, W&M) is a public research university in Williamsburg, Virginia. Founded in 1693 by letters patent issued by King William III ...
where she majored in English. After her graduation in 1979 she was hired by
ABC News ABC News is the news division of the American broadcast network ABC. Its flagship program is the daily evening newscast ''ABC World News Tonight, ABC World News Tonight with David Muir''; other programs include Breakfast television, morning ...
as a journalist. During her 10-year career as a journalist, Sanders won an
Emmy award The Emmy Awards, or Emmys, are an extensive range of awards for artistic and technical merit for the American and international television industry. A number of annual Emmy Award ceremonies are held throughout the calendar year, each with the ...
for her reporting of
Hurricane Hugo Hurricane Hugo was a powerful Cape Verde tropical cyclone that inflicted widespread damage across the northeastern Caribbean and the Southeastern United States in September 1989. Across its track, Hugo affected approximately 2 million peop ...
yet she found herself drawn to stories that focused around both mysteries as well as medicine. After about 10 years of reporting Sanders decided to pursue a career within the medical field. She got accepted into the post-baccalaureate pre-medical program at
Columbia University Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhatt ...
. After completing her pre-medical requirements she was accepted into
Yale Medical School The Yale School of Medicine is the graduate medical school at Yale University, a private research university in New Haven, Connecticut. It was founded in 1810 as the Medical Institution of Yale College and formally opened in 1813. The primary te ...
. She went on to complete her residency at Yale and became her class’ chief resident. Sanders became an attending internal medicine physician for the
Yale-New Haven Hospital Yale New Haven Hospital (YNHH) is a 1,541-bed hospital located in New Haven, Connecticut. It is owned and operated by the Yale New Haven Health System. YNHH includes the 168-bed Smilow Cancer Hospital at Yale New Haven, the 201-bed Yale New Have ...
. As her new career progressed she became part of Yale’s Department of Internal Medicine while also teaching primary care at the school of medicine. In 2002, a friend of hers working at ''
The New York Times ''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid ...
'' sparked a conversation about what doctors could provide in a literature perspective. This conversation led to an idea, and from this idea Sanders started writing a column for ''The New York Times'' called ''Diagnosis''. The column would highlight medical mysteries that she would encounter within her own patients as well as her colleagues, she would set up the stories as a mystery case revealing the diagnosis within the following week's column. The column then became inspiration for the 2004 TV series ''
House M.D. ''House'' (also called ''House, M.D.'') is an American medical drama television series that originally ran on the Fox Broadcasting Company, Fox network for eight seasons, from November 16, 2004, to May 21, 2012. The series' main character is G ...
'', where Sanders became a medical consultant for the show. Alongside writing her column for ''The New York Times'', Sanders has also written 4 books related to medicine. On August 16, 2019 a
Netflix Netflix, Inc. is an American subscription video on-demand over-the-top streaming service and production company based in Los Gatos, California. Founded in 1997 by Reed Hastings and Marc Randolph in Scotts Valley, California, it offers a fil ...
series titled ''Diagnosis'' was released and it follows Dr. Lisa Sanders as she looks to hopefully diagnose patients with difficult symptoms.


Cast

*
Lisa Sanders Lisa Sanders (born July 24, 1956) is an American physician, medical author and journalist, and associate professor of internal medicine and education at Yale School of Medicine. In 2002, she began writing a column for ''The New York Times'' called ...
- physician, narrator and columnist for ''The New York Times''. * Angel Parker- A 23 year old nursing student from Las Vegas, NV. Her symptoms are expressed through severe muscle pain episodes that render her immobile. * Sadie Gonzalez- A 7 year old little girl from Queens, NY. She suffers from frequent seizures causing physicians to suggest a
Hemispherectomy Hemispherectomy is a neurosurgical procedure in which a cerebral hemisphere (half of the upper brain, or cerebrum) is removed or disconnected that is used to treat a variety of refractory or drug-resistant seizure disorders (epilepsy). Refractory ...
as an only form of treatment. * Willie Reyes- A 46 year old Army veteran from Vado, NM. He suffers from constant seizures resulting in memory loss and mood swings. * Kamiyah Morgan- A 6 year old little girl from Vermillion, SD. She has very frequent fainting episodes where she will go limp and unresponsive, they can happen up to 300 times a day. * Lashay Hamblin- A 16 year old high school student from South Jordan, UT. She is not able to keep down any foods or liquids, her symptoms mistakenly resemble that of Bulimia. * Matt Lee- A 20 year old college student from Mt. Airy, MD. He suffers from frequent fainting spells that only come when he feels a sense of
Deja Vu Deja or Dejah may refer to: * Deja News, an archive of messages posted to Usenet discussion groups and its successor ''deja.com'' * Andreas Deja (born 1957), German animator * Dejah Mulipola (born 1998), American softball player * Dejah Thoris, a ...
, these fainting spells will also cause his heart to momentarily stop. * Joe- A 61 year old optimistic patient from Wallingford, CT. He was struck with a sudden and unexplained paralysis starting from his waist down, leaving him paraplegic. * Ann- A 42 year old skeptic patient from Wallingford, CT. She has intermittent paralysis where she could spend days with the right side of her body immobile. She will then regain mobility but the paralysis always occurs again.


Episodes


Episode 1: Detective Work

Angel Parker is a 23 year old nursing student at the time of filming the episode. The earliest memory Angel has of the beginning of her illness was when she was 14, she remembers waking up in the middle of the night not being able to move. Since then her illness has progressed into daily severe muscle pain episodes, where the pain will start at the bottom of her legs and grow its way up to jaw. These episodes render Angel immobile for hours, her pee is pitch black, and very frequently she has to be admitted to the hospital. Angel expresses that any increase in physical strain or exercise will make her symptoms worse but she doesn't let that stop her from pursuing her athletic nature. Each time she is admitted physicians are unable to find a cause for her pain; She has been tested for Rheumatoid Arthritis, Lupus, Multiple Sclerosis, and Autoimmune diseases with all negative results. Angel’s story was sent to Dr. Lisa Sanders by a colleague, where she decided to take on her case in an attempt to help Angel find answers. Dr. Lisa Sanders published Angel’s story on her column, ''Diagnosis'', asking readers to help find a diagnosis for her symptoms. One big medical anomaly that physicians are able to record during Angel’s episode is a rise in her
Creatine Kinase Creatine kinase (CK), also known as creatine phosphokinase (CPK) or phosphocreatine kinase, is an enzyme () expressed by various tissues and cell types. CK catalyses the conversion of creatine and uses adenosine triphosphate (ATP) to create phosp ...
levels.
Creatine Kinase Creatine kinase (CK), also known as creatine phosphokinase (CPK) or phosphocreatine kinase, is an enzyme () expressed by various tissues and cell types. CK catalyses the conversion of creatine and uses adenosine triphosphate (ATP) to create phosp ...
is muscle protein that at this point for Angel is leaking into her body at high levels, her highest CK level recorded during an episode was 57 thousand U/L in comparison to average levels at 22-198 U/L. After Dr. Lisa Sanders published Angel’s story, they received thousands of responses on possible diagnosis based on her symptoms. The most common response was the possibility of a
Metabolic Myopathy Metabolic myopathies are Myopathy, myopathies that result from defects in biochemical metabolism that primarily affect muscle. They are generally genetic defects that interfere with muscle's ability to create energy. At the cellular level, metaboli ...
that translates to a metabolic muscle illness and are usually caused by the muscle inability to breakdown nutrients and in turn the muscles begin to break themselves down for energy usage. As Angel gets closer to possibly having a diagnosis she starts to think about her future with children, she expresses that if her disease is something she can pass down genetically she wouldn't want to put her children at risk. A Medical student from Italy reaches out to Dr. Lisa Sanders and expresses her 4th year thesis on metabolic gene testing that could be beneficial in narrowing down a diagnosis. Angel takes the leap of faith and travels to Turin, Italy for both blood and urine testing. The testing showed that Angel had a normal metabolic gene profile resulting in the elimination of many possible metabolic disorders. The physicians in Italy submitted her genomes into a sequencing trial that could take up to two months to process but could hopefully result with a diagnosis. After the two months, Angel receives a call from the Physician with a complete result and a solid diagnosis of
Carnitine Palmitoyltransferase II Deficiency Carnitine palmitoyltransferase II deficiency is an autosomal recessively inherited genetic metabolic disorder characterized by an enzymatic defect that prevents long-chain fatty acids from being transported into the mitochondria for utilization ...
.


Episode 2: Second Opinions

Sadie Gonzalez is a 7 year old little girl from Queens, NY, with a severe brain disorder. Sadie suffers from very frequent seizures that have resulted in a slight speech and mobility impediment. Her mother recounts the first time Sadie had a seizure being the morning of the 29th of December, when Sadie was 6 years old. The seizures stopped for two months and in late February Sadies seizures started to violently progress into daily visible seizures that will affect different parts of her body at a time. At the time of recording the episode, Sadie was having a motor seizure almost every couple of minutes. Sadie was admitted into the
Columbia Presbyterian The NewYork-Presbyterian Hospital is a nonprofit academic medical center in New York City affiliated with two Ivy League medical schools, Cornell University and Columbia University. The hospital comprises seven distinct campuses located in the New Y ...
where multiple MRI’s were done showing no signs of brain damage or brain tumors. These results along with her symptoms led some physicians to believe she had Rasmussen’s. Rasmussen’s Encephalitis, explained by Dr. Lisa Sanders, is characterized by the chronic inflammation caused by T-Lymph
white blood cell White blood cells, also called leukocytes or leucocytes, are the cell (biology), cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders. All white blood cells are produced and de ...
s to invade half of the brain and destroy it. The only sure treatment for Rasmussen’s is a
hemispherectomy Hemispherectomy is a neurosurgical procedure in which a cerebral hemisphere (half of the upper brain, or cerebrum) is removed or disconnected that is used to treat a variety of refractory or drug-resistant seizure disorders (epilepsy). Refractory ...
, where the
corpus callosum The corpus callosum (Latin for "tough body"), also callosal commissure, is a wide, thick nerve tract, consisting of a flat bundle of commissural fibers, beneath the cerebral cortex in the brain. The corpus callosum is only found in placental mam ...
is severed and separated the diseased side of the brain from the healthy side. Direct consequences from this procedure is loss of vision in one eye, losing the ability to move one entire half of her body, one can also lose the ability to speak. If Sadie actually does have this disorder and does have the procedure then half of the brain can spread into the second half, causing the brain to deteriorate. The parents of Sadie reach out to Dr. Lisa Sanders in hopes of getting a second opinion, a different diagnosis, or a different treatment. Essentially looking for any route that could lead to a better life for Sadie that doesn't have to hinder her more than her disease hinders her now. Dr. Lisa Sanders put their story out onto her column and awaited for the responses. Many of the responses from the audience agreed with the diagnosis of Rasmussen’s, others suggested that the seizures could be controlled with electro stimulation therapy, and a third group suggested it was a neurologic version of
Lyme Disease Lyme disease, also known as Lyme borreliosis, is a vector-borne disease caused by the ''Borrelia'' bacterium, which is spread by ticks in the genus ''Ixodes''. The most common sign of infection is an expanding red rash, known as erythema migran ...
. She was tested for various diseases under different conditions and one specific test came back strongly positive, resulting in a diagnosis that led to a manageable treatment, and also a
responsive neurostimulation device Responsive neurostimulation device is a medical device that senses changes in a person's body and uses neurostimulation to respond in the treatment of disease. The FDA has approved devices for use in the United States in the treatment of epileptic ...
was implanted by a neurosurgeon.


Episode 3: The Wisdom of the Crowd

Willie Reyes is a 46 year old Army Veteran who is slowly losing his memories as a result of frequent seizures. Willie’s wife recounts the first time he had a seizure when he was 44 and he just fell to the floor one day without any explanation. Since the first seizure, he has developed multiple
brain lesion Neurotrauma, brain damage or brain injury (BI) is the destruction or degeneration of brain cells. Brain injuries occur due to a wide range of internal and external factors. In general, brain damage refers to significant, undiscriminating t ...
s, progressive memory loss,
hearing loss Hearing loss is a partial or total inability to Hearing, hear. Hearing loss may be present at birth or acquired at any time afterwards. Hearing loss may occur in one or both ears. In children, hearing problems can affect the ability to Language ...
, and violent/emotional mood swings. Willie says that because of his
memory loss Amnesia is a deficit in memory caused by brain damage or disease,Gazzaniga, M., Ivry, R., & Mangun, G. (2009) Cognitive Neuroscience: The biology of the mind. New York: W.W. Norton & Company. but it can also be caused temporarily by the use o ...
he forgets a lot of things and constantly repeats himself, making him feel like a child. He tells his biggest fear being waking up one day and completely forgetting about his family. His daughter highlights the fact that recently he's been starting to forget major memories, from her childhood such as her birth. Dr. Lisa Sanders took a look at Willie’s
MRI Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to form pictures of the anatomy and the physiological processes of the body. MRI scanners use strong magnetic fields, magnetic field gradients, and radio waves ...
scans and noted a huge
lesion A lesion is any damage or abnormal change in the tissue of an organism, usually caused by disease or trauma. ''Lesion'' is derived from the Latin "injury". Lesions may occur in plants as well as animals. Types There is no designated classifi ...
at the base of his brain with finger-like deterioration rooting up from it. She has a theory that the deterioration reaching the memory region of his brain could be the reason for his
memory loss Amnesia is a deficit in memory caused by brain damage or disease,Gazzaniga, M., Ivry, R., & Mangun, G. (2009) Cognitive Neuroscience: The biology of the mind. New York: W.W. Norton & Company. but it can also be caused temporarily by the use o ...
and
mood swing A mood swing is an extreme or sudden change of mood. Such changes can play a positive part in promoting problem solving and in producing flexible forward planning, or be disruptive. When mood swings are severe, they may be categorized as par ...
s. His wife states that in June 2019, he had a
biopsy A biopsy is a medical test commonly performed by a surgeon, interventional radiologist, or an interventional cardiologist. The process involves extraction of sample cells or tissues for examination to determine the presence or extent of a diseas ...
done with a piece of brain matter and the results came back as having unspecified inflammation. Dr. Sanders says that one of the biggest reasons that his condition is hard to diagnose is because it has very similar symptoms to a lot of common brain disorders, with no response to
steroid A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration. Steroids have two principal biological functions: as important components of cell membranes that alter membrane fluidity; and a ...
s. Dr. Lisa Sanders took out to publish Willie’s story and awaited the response with a possible diagnosis. Dr. Sanders expresses her disappointment in the fact that even if they are able to find a diagnosis or treatment for his illness, he may not be able to recover all the memories he has already lost. From the hundreds of responses Dr. Sanders highlighted 2 very interesting possibilities one caused by a
virus A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1 ...
and the other caused by an
autoimmune disorder An autoimmune disease is a condition arising from an abnormal immune response to a functioning body part. At least 80 types of autoimmune diseases have been identified, with some evidence suggesting that there may be more than 100 types. Nearly a ...
. The first possibility is
Progressive Multifocal Leukoencephalopathy Progressive multifocal leukoencephalopathy (PML) is a rare and often fatal viral disease characterized by progressive damage (''-pathy'') or inflammation of the white matter (''leuko-'') of the brain (''-encephalo-'') at multiple locations (''mu ...
that is caused by a virus and destroys the brain's ability to translate information. The second possibility is a very rare
autoimmune disease An autoimmune disease is a condition arising from an abnormal immune response to a functioning body part. At least 80 types of autoimmune diseases have been identified, with some evidence suggesting that there may be more than 100 types. Nearly a ...
by the name of Neuro-Behcet’s that causes inflammation and
ulceration An ulcer is a discontinuity or break in a bodily membrane that impedes normal function of the affected organ. According to Robbins's pathology, "ulcer is the breach of the continuity of skin, epithelium or mucous membrane caused by sloughing o ...
in different types of the body. Neither of these diagnoses seemed to fit Willie exactly because of key features such as Willie’s very strong
immune system The immune system is a network of biological processes that protects an organism from diseases. It detects and responds to a wide variety of pathogens, from viruses to parasitic worms, as well as cancer cells and objects such as wood splinte ...
and the fact that he had no response on steroids. Due to Willie’s background in the Army, the suggestion of the Gulf War Illness was brought up. When Dr. Sanders brought this idea to another physician for a second diagnosis, they highlighted key similarities of symptoms between Willie and the Gulf War Illness despite his being much more severe. The idea of the Gulf War Illness was tossed around as a possibility and brought up to many Physicians for second opinions, each one highlighting his symptoms are much more severe, and suggesting the possibility of testing for further clarity. To better understand the chances of Willie having GWI, they need to know if he was exposed to the toxins present during the
Gulf War The Gulf War was a 1990–1991 armed campaign waged by a 35-country military coalition in response to the Iraqi invasion of Kuwait. Spearheaded by the United States, the coalition's efforts against Iraq were carried out in two key phases: ...
. However, the military provided him with no records of any medical discrepancies caused by actions during war. If Willie was to be diagnosed with Gulf War Illness he would not have a course of treatment, he would have to learn to cope with the disease until a treatment becomes available in the hopeful near future. Willie and his wife go to visit a Marine Veteran who was diagnosed with Gulf War Illness to be able to relate any similarities and narrow down the possibilities.


Episode 4: Looking for a Village

Kamiyah Morgan is a 6 year old little girl who suffers from a very unusual set of fainting episodes that will leave her
unresponsive A coma is a deep state of prolonged unconsciousness in which a person cannot be awakened, fails to respond normally to painful stimuli, light, or sound, lacks a normal wake-sleep cycle and does not initiate voluntary actions. Coma patients exhi ...
and immobile, and they can happen up to 300 times a day. When she experiences a fainting episode she will become completely
paralyzed Paralysis (also known as plegia) is a loss of motor function in one or more muscles. Paralysis can also be accompanied by a loss of feeling (sensory loss) in the affected area if there is sensory damage. In the United States, roughly 1 in 50 ...
affecting everything in her body including her lungs, her mother states that every day that passes her ability to breathe diminishes. Kamiyah’s mother said that these fainting episodes started when she was about 8 months old as she would be crawling and suddenly tip over and go limp. At first their pediatric physician said the episodes looked like she was having a
seizure An epileptic seizure, informally known as a seizure, is a period of symptoms due to abnormally excessive or synchronous neuronal activity in the brain. Outward effects vary from uncontrolled shaking movements involving much of the body with los ...
, but after running an
EEG Electroencephalography (EEG) is a method to record an electrogram of the spontaneous electrical activity of the brain. The biosignals detected by EEG have been shown to represent the postsynaptic potentials of pyramidal neurons in the neocortex ...
there was no
seizure An epileptic seizure, informally known as a seizure, is a period of symptoms due to abnormally excessive or synchronous neuronal activity in the brain. Outward effects vary from uncontrolled shaking movements involving much of the body with los ...
being detected during the episodes. They then tried testing with
MRI Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to form pictures of the anatomy and the physiological processes of the body. MRI scanners use strong magnetic fields, magnetic field gradients, and radio waves ...
for any
brain tumor A brain tumor occurs when abnormal cells form within the brain. There are two main types of tumors: malignant tumors and benign (non-cancerous) tumors. These can be further classified as primary tumors, which start within the brain, and seconda ...
s or
malignancies Malignancy () is the tendency of a medical condition to become progressively worse. Malignancy is most familiar as a characterization of cancer. A ''malignant'' tumor contrasts with a non-cancerous ''benign'' tumor in that a malignancy is not s ...
but again there was nothing. They were then referred over to the NIH or the
National Institute of Health The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late 1 ...
where their entire purpose is to be able to research and hopefully diagnose very strange cases. They NIH tested every system and every symptom and they were unable to find anything, they submitted her blood in for testing and they have yet to hear of anything from them for over two years. When Dr. Lisa Sanders asked the NIH for Kamiyah records; they were reluctant to release them even though she had her mother's permission, very shortly after this interaction Breteni, Kamiyah’s mother, received an email from NIH to discuss Kamiyah’s results. Breteni was upset over this interaction because it took them two years to be able to come out with her daughter’s results and only after an interaction with Dr. Lisa Sanders. Dr. Sanders believed this was because they might have initially forgotten to share the results and didn't want to ligate any misinterpretations. Once Breteni received the results it was shown that Kamiyah had a break in a
gene In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
that wasn't inherited from her mother or father, it created itself. Specifically a break within the KCNMA1 gene, and she was the first patient of her kind, she's “groundbreaking”. The NIH said that it would take more patients with the same illness and a doctor to “peg” it to be able to create a disease grouping for diagnosis. When Dr. Lisa Sanders created the column for Kamiyah, instead of asking for the readers to chime in for their diagnosis, she went out looking for readers who would have the same symptoms/gene break as her. From the publication of the column, Breteni was able to find dozens of people who themselves or their children had the same KCNMA1 gene
mutation In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain either DNA or RNA. Mutations result from errors during DNA or viral replication, mi ...
. There was also a scientist who reached out to Dr. Lisa Sanders, who had based the last 20 years of her career on researching the specific ion pathway for the KCNMA1 gene. The scientist goes into detail about the
gene In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
and how it regulates the amount of
potassium Potassium is the chemical element with the symbol K (from Neo-Latin ''kalium'') and atomic number19. Potassium is a silvery-white metal that is soft enough to be cut with a knife with little force. Potassium metal reacts rapidly with atmosphe ...
that enters the
cell Cell most often refers to: * Cell (biology), the functional basic unit of life Cell may also refer to: Locations * Monastic cell, a small room, hut, or cave in which a religious recluse lives, alternatively the small precursor of a monastery w ...
s and as a result this affects the brain wave levels corresponding to movement and in theory would create the fainting episodes. Kamiyah as well as all the patients found through the column became the breakthrough needed to begin proper human research towards a diagnosis and treatment of the
gene mutation In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain either DNA or RNA. Mutations result from errors during DNA or viral replication, mitos ...
. While Kamiyah was not able to technically receive a diagnosis for her illness, she created the pathway for research into possible treatments for patients in the future.


Episode 5: A Question of Trust

Lashay Hamblin is a 16-year-old high school student at the time of filming the episode. She suffers from an illness with similarities to
Bulimia Bulimia nervosa, also known as simply bulimia, is an eating disorder characterized by binge eating followed by purging or fasting, and excessive concern with body shape and weight. The aim of this activity is to expel the body of calories eate ...
, only she has no control over her actions. Everything that Lashay eats or drinks is almost immediately thrown up and she had very bad stomach cramping because of it. She expresses her bad experience with physicians who did not want to diagnose her because at only 16 years old she shows an almost exact reflection of an
eating disorder An eating disorder is a mental disorder defined by abnormal eating behaviors that negatively affect a person's physical or mental health. Only one eating disorder can be diagnosed at a given time. Types of eating disorders include binge eating d ...
. During her adolescence in 2014 her family went on a trip to
Costa Rica Costa Rica (, ; ; literally "Rich Coast"), officially the Republic of Costa Rica ( es, República de Costa Rica), is a country in the Central American region of North America, bordered by Nicaragua to the north, the Caribbean Sea to the no ...
where she had an encounter with a wild
raccoon The raccoon ( or , ''Procyon lotor''), sometimes called the common raccoon to distinguish it from other species, is a mammal native to North America. It is the largest of the procyonid family, having a body length of , and a body weight of ...
that tore at her skin. When she got back home from the trip only two days later she had severe symptoms of
vomiting Vomiting (also known as emesis and throwing up) is the involuntary, forceful expulsion of the contents of one's stomach through the mouth and sometimes the Human nose, nose. Vomiting can be the result of ailments like Food-poisoning, foo ...
,
headache Headache is the symptom of pain in the face, head, or neck. It can occur as a migraine, tension-type headache, or cluster headache. There is an increased risk of depression in those with severe headaches. Headaches can occur as a result ...
s,
neck pain Neck pain, also known as cervicalgia, is a common problem, with two-thirds of the population having neck pain at some point in their lives. Neck pain, although felt in the neck, can be caused by numerous other spinal problems. Neck pain may arise ...
s and stomach pains. At first physicians thought it was
rabies Rabies is a viral disease that causes encephalitis in humans and other mammals. Early symptoms can include fever and tingling at the site of exposure. These symptoms are followed by one or more of the following symptoms: nausea, vomiting, vi ...
and immediately gave her the
rabies Rabies is a viral disease that causes encephalitis in humans and other mammals. Early symptoms can include fever and tingling at the site of exposure. These symptoms are followed by one or more of the following symptoms: nausea, vomiting, vi ...
vaccination, this however made everything extremely worse and all her symptoms progressed. Since that day in the emergency room she has yet to recover or improve from any of the symptoms. She's not able to walk straight up, sit in a chair, and has a constant
throbbing {{Short pages monitor