CSP-2503
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CSP-2503 is a potent and selective 5-HT1A receptor
agonist An agonist is a chemical that activates a Receptor (biochemistry), receptor to produce a biological response. Receptors are Cell (biology), cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an R ...
, 5-HT2A receptor
antagonist An antagonist is a character in a story who is presented as the main enemy or rival of the protagonist and is often depicted as a villain.5-HT3 receptor antagonist of the naphthylpiperazine class. First synthesized in 2003, it was designed based on
computational model A computational model uses computer programs to simulate and study complex systems using an algorithmic or mechanistic approach and is widely used in a diverse range of fields spanning from physics, engineering, chemistry and biology to economics ...
s and QSAR studies. In rat studies, CSP-2503 has demonstrated
anxiolytic An anxiolytic (; also antipanic or anti-anxiety agent) is a medication or other intervention that reduces anxiety. This effect is in contrast to anxiogenic agents which increase anxiety. Anxiolytic medications are used for the treatment of anxie ...
effects, and thus has been suggested as a treatment for
anxiety Anxiety is an emotion characterised by an unpleasant state of inner wikt:turmoil, turmoil and includes feelings of dread over Anticipation, anticipated events. Anxiety is different from fear in that fear is defined as the emotional response ...
in humans with a multimodal
mechanism of action In pharmacology, the term mechanism of action (MOA) refers to the specific biochemical Drug interaction, interaction through which a Medication, drug substance produces its pharmacological effect. A mechanism of action usually includes mention o ...
.


See also

* Naphthylpiperazine * S-14,671 * S-14,506


References

{{Piperazines Diketopiperazines Experimental drugs Lactams 1-(1-Naphthyl)piperazines Pyrrolopyrazines