Aharon Razin
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Aharon Razin (
Hebrew Hebrew (; ; ) is a Northwest Semitic language of the Afroasiatic language family. Historically, it is one of the spoken languages of the Israelites and their longest-surviving descendants, the Jews and Samaritans. It was largely preserved ...
: אהרון רזין; April 6, 1935 – May 27, 2019) was an Israeli biochemist.


Biography

Aharon Razin was raised in Petah Tikva. He began his academic studies at the Hebrew University of Jerusalem, majoring in physics and mathematics. He completed his M.A. and PhD in biochemistry, and did post-doctoral work at the California Institute of Technology. When he returned to Israel in 1971, he served as senior lecturer, associate professor and full professor of cellular biochemistry and human genetics at the Hebrew University Faculty of Medicine. In 1980, Razin was appointed head of the Department of Cellular Biochemistry at the Faculty of Medicine and Head of the Institute of Biochemistry. From 1988, he has held the Dr. Jacob Greenbaum Chair of Medical Sciences at Hebrew University. He is a member of the board of the Authority for Research and Development at the Hebrew University, chairman of the Planning and Development Committee of the Faculty of Medicine and member of the Israel National Academy of Sciences advisory committee on the Human Genome. He now serves as professor emeritus in the Department for Developmental Biology & Cancer Research, The Institute For Medical Research, Israel-Canada (IMRIC).


Research career

In his early studies, Razin examined the metabolism of nucleic acids and the biochemical faults in patients with gout and favism. He later studied the specific mutation with the aid of a chemically synthesized DNA-sequence, DNA methylation in gene activity and methylation pattern production of single genes in the development of the fetus.


Awards

In 2004, Razin was awarded the Israel Prize for biochemistry. In 2008, he was awarded the
Wolf Prize in Medicine The Wolf Prize in Medicine is awarded annually by the Wolf Foundation in Israel. It is one of the six Wolf Prizes established by the Foundation and awarded since 1978; the others are in Agriculture, Chemistry, Mathematics, Physics and Arts. The ...
, jointly with
Howard Cedar Howard Chaim Cedar (Hebrew: חיים סידר; born January 12, 1943) is an Israeli American biochemist who works on DNA methylation, a mechanism that turns genes on and off. Biography Howard Chaim Cedar was born in the United States. He rece ...
, for "their fundamental contributions to our understanding of the role of DNA methylation in the control of gene expression." Razin's work on chemical changes in the DNA molecule focuses on the molecular process that turns on and off some 40,000 genes in the human body. In 2009, Razin won
The EMET Prize for Art, Science and Culture ''The'' () is a grammatical article in English, denoting persons or things already mentioned, under discussion, implied or otherwise presumed familiar to listeners, readers, or speakers. It is the definite article in English. ''The'' is the m ...
. In 2011 he received the Canada Gairdner Award from the
Gairdner Foundation The Gairdner Foundation is a non-profit organization devoted to the recognition of outstanding achievements in biomedical research worldwide. It was created in 1957 by James Arthur Gairdner to recognize and reward the achievements of medical resea ...
, together with
Howard Cedar Howard Chaim Cedar (Hebrew: חיים סידר; born January 12, 1943) is an Israeli American biochemist who works on DNA methylation, a mechanism that turns genes on and off. Biography Howard Chaim Cedar was born in the United States. He rece ...
and Adrian Peter Bird, for their "pioneering discoveries on DNA methylation and its role in gene expression." In 2016 he received the
Louisa Gross Horwitz Prize The Louisa Gross Horwitz Prize for Biology or Biochemistry is an annual prize awarded by Columbia University to a researcher or group of researchers who have made an outstanding contribution in basic research in the fields of biology or biochemist ...
together with
Howard Cedar Howard Chaim Cedar (Hebrew: חיים סידר; born January 12, 1943) is an Israeli American biochemist who works on DNA methylation, a mechanism that turns genes on and off. Biography Howard Chaim Cedar was born in the United States. He rece ...
and Gary Felsenfeld.


See also

* List of Israel Prize recipients *
Science and technology in Israel Science and technology in Israel is one of the country's most developed sectors. Israel spent 4.3% of its gross domestic product (GDP) on civil research and development in 2015, the highest ratio in the world. In 2019, Israel was ranked the world' ...


Notes

{{DEFAULTSORT:Razin, Aharon 1935 births 2019 deaths Israeli biochemists Israeli Jews Israel Prize in biochemistry recipients Jewish chemists Wolf Prize in Medicine laureates Members of the Israel Academy of Sciences and Humanities