2C-T-4 (2,5-dimethoxy-4-isopropylthiophenethylamine) is a psychedelic phenethylamine of the

2C family 2C (2C-''x'') is a general name for the family of psychedelic drug, psychedelic phenethylamines containing Methoxy, methoxy groups on the 2 and 5 carbon, positions of a benzene ring. Most of these compounds also carry lipophilic substituents at the ...

. It was first synthesized by Alexander Shulgin and is used as

entheogen Entheogens are psychoactive substances that induce alterations in perception, mood, consciousness, cognition, or behavior for the purposes of engendering spiritual development or otherwiseRätsch, Christian, ''The Encyclopedia of Psychoac ...

ic recreational drug.

Chemistry

2C-T-4 is the 2-carbon

homolog In biology, homology is similarity due to shared ancestry between a pair of structures or genes in different taxa. A common example of homologous structures is the forelimbs of vertebrates, where the wings of bats and birds, the arms of prima ...

of aleph-4. The full chemical name is 2- -( -(isopropylThio-">thio)-2,5-dimethoxy.html" ;"title="isopropylThio-.html" ;"title="isopropyl.html" ;"title="-(isopropyl">-(isopropylThio-">thio)-2,5-dimethoxy">isopropylThio-.html" ;"title="isopropyl.html" ;"title="-(isopropyl">-(isopropylThio-">thio)-2,5-dimethoxyphenyl]-ethyl group, ethanamine. The drug has structure, structural and pharmacodynamic properties similar to 2C-T-7 and 2C-T-19.

Effects

2C-T-4 produces psychedelic and entheogenic effects that develop slowly and can last 8–16 hours. While users may experience virtually no effects for the first hour after ingestion, results vary drastically between individuals and range from

hallucination A hallucination is a perception in the absence of an external stimulus that has the qualities of a real perception. Hallucinations are vivid, substantial, and are perceived to be located in external objective space. Hallucination is a combinati ...

and euphoria to intense sickness and anxiety. Shulgin devoted a chapter in the first part of his book '' PiHKAL'' to this compound, describing an intense "plus-four" psychedelic experience mediated by a twelve milligram dose.

Pharmacology

The mechanism that produces 2C-T-4’s hallucinogenic and entheogenic effects has not been specifically established, however it is most likely to result from action as a 5-HT_2A serotonin receptor agonist in the brain, a mechanism of action shared by all of the hallucinogenic tryptamines and phenethylamines for which the mechanism of action is known.

Popularity

2C-T-4 is relatively unknown on the black market, but has been sold to a limited extent on the research chemical market.

Drug prohibition laws

Canada

As of October 31, 2016, 2C-T-4 is a controlled substance (Schedule III) in Canada.

China

As of October 2015 2C-T-4 is a controlled substance in China.

Denmark

2C-T-4 is added to the list of Schedule B controlled substances.

Sweden

''Sveriges riksdags'' health ministry ''Statens folkhälsoinstitut'' classified 2C-T-4 as "health hazard" under the act ''Lagen om förbud mot vissa hälsofarliga varor'' (translated ''Act on the Prohibition of Certain Goods Dangerous to Health'') as of Jul 15, 2007, in their regulation SFS 2007:600 listed as 2,5-dimetoxi-4-isopropyltiofenetylamin (2C-T-4), making it illegal to sell or possess.

United States

As of July 9, 2012, 2C-T-4 is a Schedule I substance in the United States, under the Synthetic Drug Abuse Prevention Act of 2012.

Homologue

2C-T-4 has one homologue, the structural isomer Ψ-2C-T-4 (2,6-dimethoxy-4-(i)-propylthiophenethylamine). This compound was tested by Alexander Shulgin at a dose of 12 mg. At this dosage its duration was very short and it produced few effects, however based on the research into the better characterized compound Ψ-DOM, the potency of Ψ-2C-T-4 is likely to be around 1/3 that of 2C-T-4 itself, so a more effective dosage of Ψ-2C-T-4 might be in the region of 20–60 mg; however high doses such as this might well be associated with toxic side effects, and so extreme caution would be advised.

References

External links

PiHKAL #41 2C-T-4

2C-T-4 Entry in PiHKAL • info

Ψ-2C-T-4 Entry in PiHKAL • info
{{Hallucinogenic phenethylamines 2C (psychedelics) Thioethers Designer drugs Isopropyl compounds