2C-T-15 or 2,5-dimethoxy-4-(β-cyclopropylthio)phenethylamine is a
psychedelic
Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary states of consciousness (known as psychedelic experiences or "trips").Pollan, Michael (2018). ''How to Change Your Mind: What the New Science o ...
phenethylamine
Phenethylamine (PEA) is an organic compound, natural monoamine alkaloid, and trace amine, which acts as a central nervous system stimulant in humans. In the brain, phenethylamine regulates monoamine neurotransmission by binding to trace am ...
of the
2C family. It was presumably first synthesized by
Alexander Shulgin
Alexander Theodore "Sasha" Shulgin (June 17, 1925 – June 2, 2014) was an American medicinal chemist, biochemist, organic chemist, pharmacologist, psychopharmacologist, and author. He is credited with introducing 3,4-methylenedioxymetha ...
and reported in his book ''
PiHKAL (Phenethylamines i Have Known And Loved)''.
Chemistry
2C-T-15 is the
2 carbon homologue of
Aleph-15, which has not been synthesized. The full chemical name is 2-
-(2- -(2-cyclopropylThio-">thio)-2,5-dimethoxy.html" ;"title="cyclopropylThio-.html" ;"title="cyclopropyl.html" ;"title="-(2-cyclopropyl">-(2-cyclopropylThio-">thio)-2,5-dimethoxy">cyclopropylThio-.html" ;"title="cyclopropyl.html" ;"title="-(2-cyclopropyl">-(2-cyclopropylThio-">thio)-2,5-dimethoxyphenyl]ethanamine. The drug has structure, structural properties similar to 2C-T-2 and other drugs in the 2C-T series.
General information
The dosage range of 2C-T-15 is typically 30
mg or more. Its duration is unspecified by
Shulgin Shulgin (russian: Шульгин) is a Russian masculine surname, its feminine counterpart is Shulgina. It may refer to
*Alexander Shulgin (1925–2014), American pharmacologist and drug developer
** Shulgin Rating Scale
* Alexander Shulgin (musici ...
, and it
entry in PiHKALsays it lasts for "several hours." The effects are not prominent, and 2C-T-15 is not very potent.
Pharmacology
The mechanism that produces 2C-T-15's hallucinogenic and entheogenic effects has not been specifically established, however it is most likely to result from action as a
5-HT2A serotonin receptor
5-HT receptors, 5-hydroxytryptamine receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory ne ...
agonist
An agonist is a chemical that activates a receptor to produce a biological response. Receptors are cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an antagonist blocks the action of the ag ...
in the brain, a mechanism of action shared by all of the hallucinogenic tryptamines and phenethylamines for which the mechanism of action is known.
Dangers
The toxicity of 2C-T-15 is not well documented. 2C-T-15 is much less potent than 2C-T-7, but it may be expected that at very high doses it would display similar toxicity to that of other phenethylamines of the 2C-T family.
Legality
2C-T-15 is not explicitly illegal in the USA, but possession and sales of 2C-T-15 could be prosecuted under the
Federal Analog Act
The Federal Analogue Act, , is a section of the United States Controlled Substances Act passed in 1986 which allows any chemical "substantially similar" to a controlled substance listed in Schedule I or II to be treated as if it were listed in ...
because of its structural similarities to
2C-T-7
2C-T-7 is a psychedelic phenethylamine of the 2C family. In his book '' PiHKAL: A Chemical Love Story'', Alexander Shulgin lists the dosage range as 10 to 30 mg. 2C-T-7 is generally taken orally, and produces psychedelic and entactogenic eff ...
.
2C-T-15 is a class A drug in the UK under the
Misuse of Drugs act.
As of October 31, 2016, 2C-T-15 is a controlled substance (Schedule III) in Canada.
References
External links
PiHKAL #47 2C-T-152C-T-15 Entry in PiHKAL • info
{{DEFAULTSORT:2c-T-15
2C (psychedelics)
Thioethers
Cyclopropyl compounds