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Alphaherpesvirinae
''Alphaherpesvirinae'' is a subfamily of viruses in the family ''Herpesviridae'', primarily distinguished by reproducing more quickly than other subfamilies in the ''Herpesviridae''. In animal virology the most important herpesviruses belong to the Alphaherpesvirinae. Pseudorabies virus is the causative agent of Aujeszky's disease in pigs and ''Bovine herpesvirus 1'' is the causative agent of bovine infectious rhinotracheitis and pustular vulvovaginitis. Mammals serve as natural hosts. There are currently 45 species in this subfamily, divided among 5 genera with one species unassigned to a genus. Diseases associated with this subfamily include: HHV-1 and HHV-2: skin vesicles or mucosal ulcers, rarely encephalitis and meningitis, HHV-3: chickenpox (varicella) and shingles, GaHV-2: Marek's disease. Genera ''Alphaherpesvirinae'' consists of the following five genera: * '' Iltovirus'' * '' Mardivirus'' * ''Scutavirus'' * '' Simplexvirus'' * ''Varicellovirus'' The species ''C ...
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Alphaherpesvirinae
''Alphaherpesvirinae'' is a subfamily of viruses in the family ''Herpesviridae'', primarily distinguished by reproducing more quickly than other subfamilies in the ''Herpesviridae''. In animal virology the most important herpesviruses belong to the Alphaherpesvirinae. Pseudorabies virus is the causative agent of Aujeszky's disease in pigs and ''Bovine herpesvirus 1'' is the causative agent of bovine infectious rhinotracheitis and pustular vulvovaginitis. Mammals serve as natural hosts. There are currently 45 species in this subfamily, divided among 5 genera with one species unassigned to a genus. Diseases associated with this subfamily include: HHV-1 and HHV-2: skin vesicles or mucosal ulcers, rarely encephalitis and meningitis, HHV-3: chickenpox (varicella) and shingles, GaHV-2: Marek's disease. Genera ''Alphaherpesvirinae'' consists of the following five genera: * '' Iltovirus'' * '' Mardivirus'' * ''Scutavirus'' * '' Simplexvirus'' * ''Varicellovirus'' The species ''C ...
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Herpesvirales
The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans caused by members of this order include cold sores, genital herpes, chickenpox, shingles, and glandular fever. ''Herpesvirales'' is the sole order in the class ''Herviviricetes'', which is the sole class in the phylum ''Peploviricota''. Virology Morphology All members of the order have a virion structure that consists of a DNA core surrounded by an icosahedral capsid composed of 12 pentavalent and 150 hexavalent capsomeres (T = 16). The capsid has a diameter of ~110 nanometers (nm) and is embedded in a proteinaceous matrix called the tegument, which in its turn is enclosed by a glycoprotein-containing lipid envelope with a diameter of about 200 nm. The DNA genome is linear and double stranded, with sizes in the range 125–2 ...
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Chelonid Alphaherpesvirus 6
''Chelonid alphaherpesvirus 6'' (ChHV-6) is a species of virus of uncertain generic placement in the subfamily ''Alphaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans ...''. References External links * Alphaherpesvirinae {{Virus-stub ...
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Mardivirus
''Mardivirus'' is a genus of viruses in the order ''Herpesvirales'', in the family ''Herpesviridae'', in the subfamily ''Alphaherpesvirinae''. Chickens, turkeys, and quail serve as natural hosts. There are six species in this genus. Diseases associated with this genus include: Marek's disease, which causes asymmetric paralysis of one or more limbs, neurological symptoms, and development of multiple lymphomas that manifest as solid tumors. ''Gallid herpesvirus 2'' (also known as Marek's disease virus) is the only one of these viruses known to be pathogenic and due to the antigenic similarity between the three viruses the other two have been used to vaccinate against Marek's disease. These viruses have double stranded DNA genomes with no RNA intermediate. Species The genus consists of the following six species: * '' Anatid alphaherpesvirus 1'' * '' Columbid alphaherpesvirus 1'' * '' Gallid alphaherpesvirus 2'' * '' Gallid alphaherpesvirus 3'' * '' Meleagrid alphaherpesvirus 1'' ...
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Herpesviridae
''Herpesviridae'' is a large family of DNA viruses that cause infections and certain diseases in animals, including humans. The members of this family are also known as herpesviruses. The family name is derived from the Greek word ''ἕρπειν'' ( 'to creep'), referring to spreading cutaneous lesions, usually involving blisters, seen in flares of herpes simplex 1, herpes simplex 2 and herpes zoster (shingles). In 1971, the International Committee on the Taxonomy of Viruses (ICTV) established ''Herpesvirus'' as a genus with 23 viruses among four groups. As of 2020, 115 species are recognized, all but one of which are in one of the three subfamilies. Herpesviruses can cause both latent and lytic infections. Nine herpesvirus types are known to primarily infect humans, at least five of which – herpes simplex viruses 1 and 2 (HSV-1 and HSV-2, also known as HHV-1 and HHV-2; both of which can cause orolabial herpes and genital herpes), varicella zoster virus (or HHV-3; the cau ...
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Iltovirus
''Iltovirus'' is a genus of viruses in the order ''Herpesvirales'', in the family ''Herpesviridae'', in the subfamily ''Alphaherpesvirinae''. Birds, galliform birds, psittacine birds, chicken The chicken (''Gallus gallus domesticus'') is a domesticated junglefowl species, with attributes of wild species such as the grey and the Ceylon junglefowl that are originally from Southeastern Asia. Rooster or cock is a term for an adu ...s, turkeys, and quail serve as natural hosts. There are only two species in this genus. Diseases associated with this genus include: acute respiratory diseases: gaHV-1: infectious laryngotracheitis; psHV-1: Pacheco's disease. Species The genus consists of the following two species: * '' Gallid alphaherpesvirus 1'' * '' Psittacid alphaherpesvirus 1'' Structure Viruses in ''Iltovirus'' are enveloped, with icosahedral, spherical to pleomorphic, and round geometries, and T=16 symmetry. The diameter is around 120-200 nm. Genomes are lin ...
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Varicellovirus
''Varicellovirus'' (var′i-sel′ō-vi′rŭs) is a genus of viruses belonging to subfamily ''Alphaherpesvirinae'', a member of family ''Herpesviridae''. Humans and other mammals serve as natural hosts. There are 19 species in this genus. Diseases associated with this genus include: HHV-3—chickenpox (varicella) and shingles; BoHV-1—infectious bovine rhinotracheitis/infectious pustular vulvovaginitis (IPV); SuHV-1 (also known as pseudorabies virus)— Aujesky's disease characterized by central nervous system signs (hindleg paralysis, meningoencephalitis), high mortality rates in young animals, and respiratory illness in older pigs. Species The genus consists of the following 19 species: * ''Bovine alphaherpesvirus 1'' * '' Bovine alphaherpesvirus 5'' * '' Bubaline alphaherpesvirus 1'' * '' Canid alphaherpesvirus 1'' * '' Caprine alphaherpesvirus 1'' * '' Cercopithecine alphaherpesvirus 9'' * '' Cervid alphaherpesvirus 1'' * '' Cervid alphaherpesvirus 2'' * '' Cervid alphah ...
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Scutavirus
''Scutavirus'' is a genus of viruses in the order ''Herpesvirales'', in the family ''Herpesviridae'', in the subfamily ''Alphaherpesvirinae''. Turtles and tortoises serve as natural hosts. Diseases associated with this genus include fibropapillomatosis. Species The genus consists of the following two species: * ''Chelonid alphaherpesvirus 5'' * ''Testudinid alphaherpesvirus 3'' Structure Viruses in ''Scutavirus'' are enveloped, with icosahedral, spherical to pleomorphic, and round geometries, and T=16 symmetry. The diameter is around 150-200 nm. Genomes are linear and non-segmented. Life cycle Viral replication is nuclear, and is lysogenic Lysogeny, or the lysogenic cycle, is one of two cycles of viral reproduction (the lytic cycle being the other). Lysogeny is characterized by integration of the bacteriophage nucleic acid into the host bacterium's genome or formation of a circu .... Entry into the host cell is achieved by attachment of the viral gB, gC, gD ...
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Bovine Herpesvirus 1
''Bovine alphaherpesvirus 1'' (BoHV-1) is a virus of the family ''Herpesviridae'' and the subfamily ''Alphaherpesvirinae'', known to cause several diseases worldwide in cattle, including rhinotracheitis, vaginitis, balanoposthitis, abortion, conjunctivitis, and enteritis. BoHV-1 is also a contributing factor in shipping fever, also known as bovine respiratory disease (BRD). It is spread horizontally through sexual contact, artificial insemination, and aerosol transmission and it may also be transmitted vertically across the placenta. BoHV-1 can cause both clinical and subclinical infections, depending on the virulence of the strain. Although these symptoms are mainly non-life-threatening it is an economically important disease as infection may cause a drop in production and affect trade restrictions. Like other herpesviruses, BoHV-1 causes a lifelong latent infection and sporadic shedding of the virus. The sciatic nerve and trigeminal nerve are the sites of latency. A rea ...
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Simplexvirus
''Simplexvirus'' is a genus of viruses in the order ''Herpesvirales'', in the family ''Herpesviridae'', in the subfamily ''Alphaherpesvirinae''. Humans and mammals serve as natural hosts. Diseases associated with this genus include skin vesicles or mucosal ulcers, rarely encephalitis, and meningitis. Species The following 15 species are assigned to the genus: * '' Ateline alphaherpesvirus 1'' * '' Bovine alphaherpesvirus 2'' * '' Cercopithecine alphaherpesvirus 2'' * '' Human alphaherpesvirus 1'' * ''Human alphaherpesvirus 2 ''Human alphaherpesvirus 2'' (HHV-2) is a species of virus in the genus ''Simplexvirus'', subfamily ''Alphaherpesvirinae'', family '' Herpesviridae'', and order '' Herpesvirales''. Evolution ''Human alphaherpesvirus 2'' can be divided into two ...'' * '' Leporid alphaherpesvirus 4'' * '' Macacine alphaherpesvirus 1'' * '' Macacine alphaherpesvirus 2'' * '' Macacine alphaherpesvirus 3'' * '' Macropodid alphaherpesvirus 1'' * '' Macropodid alphaherpesviru ...
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Animal Virology
Veterinary virology is the study of viruses in non-human animals. It is an important branch of veterinary medicine. Rhabdoviruses Rhabdoviruses are a diverse family of single stranded, negative sense RNA viruses that infect a wide range of hosts, from plants and insects, to fish and mammals. The ''Rhaboviridae'' family consists of six genera, two of which, cytorhabdoviruses and nucleorhabdoviruses, only infect plants. Novirhabdoviruses infect fish, and vesiculovirus, lyssavirus and ephemerovirus infect mammals, fish and invertebrates. The family includes pathogens such as rabies virus, vesicular stomatitis virus and potato yellow dwarf virus that are of public health, veterinary, and agricultural significance. Foot-and-mouth disease virus Foot-and-mouth disease virus (FMDV) is a member of the Aphthovirus genus in the Picornaviridae family and is the cause of foot-and-mouth disease in pigs, cattle, sheep and goats. It is a non-enveloped, positive strand, RNA virus. FMDV is ...
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Microtubule
Microtubules are polymers of tubulin that form part of the cytoskeleton and provide structure and shape to eukaryotic cells. Microtubules can be as long as 50 micrometres, as wide as 23 to 27  nm and have an inner diameter between 11 and 15 nm. They are formed by the polymerization of a dimer of two globular proteins, alpha and beta tubulin into protofilaments that can then associate laterally to form a hollow tube, the microtubule. The most common form of a microtubule consists of 13 protofilaments in the tubular arrangement. Microtubules play an important role in a number of cellular processes. They are involved in maintaining the structure of the cell and, together with microfilaments and intermediate filaments, they form the cytoskeleton. They also make up the internal structure of cilia and flagella. They provide platforms for intracellular transport and are involved in a variety of cellular processes, including the movement of secretory vesicles, ...
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