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Aglaia Foveolata
''Aglaia foveolata'' is a species of tropical tree in the family Meliaceae. This plant occurs in Brunei, Indonesia, and Malaysia. It produces edible fruit. The bark contains silvestrol which is a potent inhibitor of ebola virus and Zika Virus ''Zika virus'' (ZIKV; pronounced or ) is a member of the virus family ''Flaviviridae''. It is spread by daytime-active '' Aedes'' mosquitoes, such as '' A. aegypti'' and '' A. albopictus''. Its name comes from the Ziika Forest of Uganda, w ... replication. References foveolata Near threatened plants Taxonomy articles created by Polbot {{Meliaceae-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Species
In biology, a species is the basic unit of classification and a taxonomic rank of an organism, as well as a unit of biodiversity. A species is often defined as the largest group of organisms in which any two individuals of the appropriate sexes or mating types can produce fertile offspring, typically by sexual reproduction. Other ways of defining species include their karyotype, DNA sequence, morphology, behaviour or ecological niche. In addition, paleontologists use the concept of the chronospecies since fossil reproduction cannot be examined. The most recent rigorous estimate for the total number of species of eukaryotes is between 8 and 8.7 million. However, only about 14% of these had been described by 2011. All species (except viruses) are given a two-part name, a "binomial". The first part of a binomial is the genus to which the species belongs. The second part is called the specific name or the specific epithet (in botanical nomenclature, also sometimes i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Meliaceae
Meliaceae, the mahogany family, is a flowering plant family of mostly trees and shrubs (and a few herbaceous plants, mangroves) in the order Sapindales. They are characterised by alternate, usually pinnate leaves without stipules, and by syncarpous, apparently bisexual (but actually mostly cryptically unisexual) flowers borne in panicles, cymes, spikes, or clusters. Most species are evergreen, but some are deciduous, either in the dry season or in winter. The family includes about 53 genera and about 600 known species, with a pantropical distribution; one genus ('' Toona'') extends north into temperate China and south into southeast Australia, another (''Synoum'') into southeast Australia, and another (''Melia'') nearly as far north. They most commonly grow as understory trees in rainforests, but are also found in mangroves and arid regions. The fossil record of the family extends back into the Late Cretaceous. Uses Various species are used for vegetable oil, soap-making, i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brunei
Brunei ( , ), formally Brunei Darussalam ( ms, Negara Brunei Darussalam, Jawi: , ), is a country located on the north coast of the island of Borneo in Southeast Asia. Apart from its South China Sea coast, it is completely surrounded by the Malaysian state of Sarawak. It is separated into two parts by the Sarawak district of Limbang. Brunei is the only sovereign state entirely on Borneo; the remainder of the island is divided between Malaysia and Indonesia. , its population was 460,345, of whom about 100,000 live in the capital and largest city, Bandar Seri Begawan. The government is an absolute monarchy ruled by its Sultan, entitled the Yang di-Pertuan, and implements a combination of English common law and sharia law, as well as general Islamic practices. At the peak of the Bruneian Empire, Sultan Bolkiah (reigned 1485–1528) is claimed to have had control over most regions of Borneo, including modern-day Sarawak and Sabah, as well as the Sulu Archipelago off ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Indonesia
Indonesia, officially the Republic of Indonesia, is a country in Southeast Asia and Oceania between the Indian and Pacific oceans. It consists of over 17,000 islands, including Sumatra, Java, Sulawesi, and parts of Borneo and New Guinea. Indonesia is the world's largest archipelagic state and the 14th-largest country by area, at . With over 275 million people, Indonesia is the world's fourth-most populous country and the most populous Muslim-majority country. Java, the world's most populous island, is home to more than half of the country's population. Indonesia is a presidential republic with an elected legislature. It has 38 provinces, of which nine have special status. The country's capital, Jakarta, is the world's second-most populous urban area. Indonesia shares land borders with Papua New Guinea, East Timor, and the eastern part of Malaysia, as well as maritime borders with Singapore, Vietnam, Thailand, the Philippines, Australia, Palau, and India ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Malaysia
Malaysia ( ; ) is a country in Southeast Asia. The federation, federal constitutional monarchy consists of States and federal territories of Malaysia, thirteen states and three federal territories, separated by the South China Sea into two regions: Peninsular Malaysia and Borneo's East Malaysia. Peninsular Malaysia shares a land and maritime Malaysia–Thailand border, border with Thailand and Maritime boundary, maritime borders with Singapore, Vietnam, and Indonesia. East Malaysia shares land and maritime borders with Brunei and Indonesia, and a maritime border with the Philippines and Vietnam. Kuala Lumpur is the national capital, the country's largest city, and the seat of the Parliament of Malaysia, legislative branch of the Government of Malaysia, federal government. The nearby Planned community#Planned capitals, planned capital of Putrajaya is the administrative capital, which represents the seat of both the Government of Malaysia#Executive, executive branch (the Cabine ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Silvestrol
Silvestrol is a natural product from the flavagline family, with a cyclopenta enzofuran core structure and an unusual dioxane ether side chain, which is found in the bark of trees from the genus ''Aglaia'', especially '' Aglaia silvestris'' and '' Aglaia foveolata''. Bioactivity It acts as a potent and selective inhibitor of the RNA helicase enzyme eIF4A, and has both broad-spectrum antiviral activity against diseases such as Ebola and coronaviruses, and anti-cancer properties, which makes it of considerable interest in medical research. However, as it cannot be extracted from tree bark in commercial amounts and is prohibitively complex to produce synthetically, practical applications have focused more on structurally simplified analogues such as CR-31-B. See also * Rocaglamide Rocaglamide is a natural product which belongs to a class of molecules called flavaglines. This compound was isolated in 1982 by King, Ming-Lu (金明儒) and colleagues based on its antileukemic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ebola Virus
''Zaire ebolavirus'', more commonly known as Ebola virus (; EBOV), is one of six known species within the genus '' Ebolavirus''. Four of the six known ebolaviruses, including EBOV, cause a severe and often fatal hemorrhagic fever in humans and other mammals, known as Ebola virus disease (EVD). Ebola virus has caused the majority of human deaths from EVD, and was the cause of the 2013–2016 epidemic in western Africa, which resulted in at least suspected cases and confirmed deaths. Ebola virus and its genus were both originally named for Zaire (now the Democratic Republic of the Congo), the country where it was first described, and was at first suspected to be a new "strain" of the closely related Marburg virus. The virus was renamed "Ebola virus" in 2010 to avoid confusion. Ebola virus is the single member of the species ''Zaire ebolavirus'', which is assigned to the genus '' Ebolavirus'', family '' Filoviridae'', order '' Mononegavirales''. The members of the species are ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Zika Virus
''Zika virus'' (ZIKV; pronounced or ) is a member of the virus family ''Flaviviridae''. It is spread by daytime-active '' Aedes'' mosquitoes, such as '' A. aegypti'' and '' A. albopictus''. Its name comes from the Ziika Forest of Uganda, where the virus was first isolated in 1947. ''Zika virus'' shares a genus with the dengue, yellow fever, Japanese encephalitis, and West Nile viruses. Since the 1950s, it has been known to occur within a narrow equatorial belt from Africa to Asia. From 2007 to , the virus spread eastward, across the Pacific Ocean to the Americas, leading to the 2015–2016 Zika virus epidemic. The infection, known as Zika fever or ''Zika virus'' disease, often causes no or only mild symptoms, similar to a very mild form of dengue fever. While there is no specific treatment, paracetamol (acetaminophen) and rest may help with the symptoms. Zika can spread from a pregnant woman to her baby. This can result in microcephaly, severe brain malformations, and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aglaia
''Aglaia'' is a genus of 117 species of woody dioecious trees belonging to the Mahogany family (Meliaceae). These trees occur in the subtropical and tropical forests of Southeast Asia, Northern Australia and the Pacific. Some species are important timber trees; others have scented flowers, or medicinal properties (the edible fruits duku or langsat have now been placed in the genus '' Lansium''). Many have complex biological relationships with their dispersal agents. Phytochemistry Species in the genus ''Aglaia'' synthesize a unique class of highly bioactive chemical compounds known as flavaglines. Over 50 unique compounds of this class have been described so far, including rocaglamide, aglafoline, silvestrol, pannellin, episilvestrol, and ponapensin. They are known for their anti-cancer, anti-fungal, anti-inflammatory and insecticidal properties. Several of these compounds have been shown to be exceptional therapeutic agents for cancer chemotherapy, however further res ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Near Threatened Plants
NEAR or Near may refer to: People * Thomas J. Near, US evolutionary ichthyologist * Near, a developer who created the higan emulator Science, mathematics, technology, biology, and medicine * National Emergency Alarm Repeater (NEAR), a former alarm device to warn civilians of a foreign nuclear attack on the United States * National Emergency Airway Registry (NEAR), a patient registry for intubations in the United States * Nicking enzyme amplification reaction (NEAR), a method of DNA amplification * NEAR Shoemaker, a spacecraft that studied the near-Earth asteroid Eros * Nearness or proximity space *"Near", a city browser by NearGlobal Television, film, music, and books * Near (Death Note), ''Nate River'', a character Other uses * Near v. Minnesota, a U.S. press freedom Supreme Court decision * New England Auto Racers Hall of Fame The New England Auto Racers Hall of Fame is a hall of fame for racing-related people in the New England region of the United States. NEAR w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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