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Varian Medical Systems is an American radiation oncology treatments and software maker based in Palo Alto, California. Their medical devices include linear accelerators (LINACs) and software for treating cancer and other medical conditions with radiotherapy, radiosurgery,
proton therapy In medicine, proton therapy, or proton radiotherapy, is a type of particle therapy that uses a beam of protons to irradiate diseased tissue, most often to treat cancer. The chief advantage of proton therapy over other types of external beam ra ...
, and
brachytherapy Brachytherapy is a form of radiation therapy where a sealed radiation source is placed inside or next to the area requiring treatment. ''Brachy'' is Greek for short. Brachytherapy is commonly used as an effective treatment for cervical, pro ...
. The company supplies software for managing cancer clinics, radiotherapy centers, and medical oncology practices. Varian Medical Systems employs more than 7,100 people at manufacturing sites in North America, Europe, and China and approximately 70 sites globally. In August 2020,
Siemens Healthineers Siemens Healthineers AG (formerly Siemens Healthcare, Siemens Medical Solutions, Siemens Medical Systems) is a German medical device company. It is the parent company for several medical technology companies and is headquartered in Erlangen, Ger ...
announced plans to acquire Varian for $16.4 billion. The deal was completed on April 15, 2021. After the merger it will continue to operate independently and will retain its headquarters along with its 10,000 employees.


History

Varian was founded in 1948 as Varian Associates by Russell H. Varian, Sigurd F. Varian,
William Webster Hansen William is a male given name of Germanic origin.Hanks, Hardcastle and Hodges, ''Oxford Dictionary of First Names'', Oxford University Press, 2nd edition, , p. 276. It became very popular in the English language after the Norman conquest of Eng ...
, and
Edward Ginzton Edward Leonard Ginzton (December 27, 1915 – August 13, 1998) was a Ukrainian- American engineer. Education Ginzton completed his B.S. (1936) and M.S. (1937) in Electrical Engineering at the University of California, Berkeley, and his P ...
to sell the Klystron, the first tube which could generate electromagnetic waves at microwave frequencies, and other electromagnetic equipment. By 1999, Varian Associates had branched into semiconductor, vacuum tube, and medical device fields. On April 2, 1999 these divisions split to become
Varian Semiconductor Varian Semiconductor Equipment Associates, Inc. was a supplier of ion implantation equipment used in the fabrication of semiconductor chips. Varian Semiconductor was founded in 1971 as Extrion Corporation in Peabody, Massachusetts. Extrion later ...
, Varian, Inc. and Varian Medical Systems. In August 2020, Siemens Healthineers AG announced that it plans to acquire Varian Medical Systems in an all-stock deal valued at $16.4 billion. The deal was approved and completed on 15 April 2021. After the merger Varian will continue to operate independently and will retain its headquarters along with its 10,000 employees.


Acquired companies

Varian Medical Systems has acquired other companies including Pan-Pacific Enterprises, ACCEL Instruments, Bio-Imaging Research, Inc. Sigma Micro Informatique Conseil, Argus Software, Dosetek Oy, Velocity Medical Solutions. and MeVis Medical Solutions AG. In January 2018, the company announced the acquisition of Sirtex Medical for $1.3 billion. In 2019, the company acquired CyberHeart, a privately-held company with intellectual property (IP) that covers the use of radiation in the heart (cardiac radioablation) and other forms of radiosurgery for cardiovascular disease.


Spin-off companies

On January 30, 2017, spin-off of Varex Imaging Corporation (manufacturing of X-ray imaging products) from Varian Medical Systems had been successfully completed.


Products


Linear accelerators

Varian manufactures a range of
megavoltage Megavoltage X-rays are produced by linear accelerators ("linacs") operating at voltages in excess of 1000  kV (1 MV) range, and therefore have an energy in the MeV range. The voltage in this case refers to the voltage used to accelerat ...
LINACs with varying levels of features and complexity, for example different numbers of
multileaf collimator A multileaf collimator (MLC) is a Collimator or beam-limiting device that is made of individual "leaves" of a high atomic numbered material, usually tungsten, that can move independently in and out of the path of a radiotherapy beam in order to sh ...
s or the ability to perform radiosurgery. TrueBeam is a radiotherapy system. The EDGE radiosurgery suite was launched in 2012. The first cancer centers to use the new system were the Champalimaud Foundation in Lisbon, Portugal and Henry Ford Health System in Detroit, Michigan.


Halcyon

In 2017, Varian launched Halcyon. The system features unique dual-layer MLC that enables high modulation with low leakage for every field or arc. Halcyon is advertised to be intuitive, friendly and comfortable for clinical staff and patient alike. This is primarily done by automating several functions typically performed manually by radiographers, such as switching between treatment beams automatically. Additionally, Halcyon also features an automated machine performance check for daily LINAC quality assurance, which can speed up the checking of beam constancy and mechanical performance through the use of a phantom. However, while Halcyon does boast improved automation and workflow improvements which allow for faster patient treatment, these extra automation tasks can make occasionally make it more difficult for medical physicists to perform detailed Quality Assurance on LINAC performance. Nevertheless, automation in both quality assurance and clinical operation generally make the LINAC easier to operate by checkers and radiation therapists.


Proton Therapy

Varian manufactures the ProBeam Proton Therapy System, with current and planned installations at several sites globally. These are an all
pencil-beam scanning Pencil beam scanning is the practice of steering a beam of radiation or charged particles across an object. It is often used in proton therapy, to reduce unnecessary radiation exposure to surrounding non-cancerous cells. Ionizing radiation Ionizi ...
proton therapy system utilizing IMPT (intensity modulated proton therapy), which was developed with PSI of Switzerland. Varian also develops
medical software Medical software is any software item or system used within a medical context, such as:reducing the paperwork, tracking patient activity * standalone software used for diagnostic or therapeutic purposes; * software embedded in a medical device (o ...
and radiology information system for proton treatment planning system.


Ethos Therapy

On September 16, 2019, during the 2019 American Society for Radiation Oncology (ASTRO) annual meeting, being held Sept. 15-18 in Chicago, Varian announced Ethos therapy, an artificial intelligence (AI)-driven holistic solution designed to increase the capability, flexibility and efficiency of radiotherapy. This new solution is designed to deliver an entire adaptive treatment in a typical 15-minute timeslot, from patient setup through treatment delivery.


Litigation


Defamation case law

In 1999, Varian Medical Systems, Inc. sued a former employee for defamation after they posted numerous messages criticizing the company on the Internet. The lawsuit led to the ruling of '' Varian v. Delfino'' by the
California Supreme Court The Supreme Court of California is the highest and final court of appeals in the courts of the U.S. state of California. It is headquartered in San Francisco at the Earl Warren Building, but it regularly holds sessions in Los Angeles and Sac ...
on the question whether a trial could proceed while denial of the defendant's
anti-SLAPP Strategic lawsuits against public participation (also known as SLAPP suits or intimidation lawsuits), or strategic litigation against public participation, are lawsuits intended to censor, intimidate, and silence critics by burdening them with t ...
motion was under appeal. After the state supreme court ruled that a new trial would be necessary because of that technical concern, the case was settled on undisclosed terms.


University of Pittsburgh

On April 25, 2012, a US federal judge in Pittsburgh awarded attorney fees, costs, and doubled damages totaling $73.6 million to the University of Pittsburgh after the university won a suit on medical patent infringement grounds against Varian.


References


External links

* {{authority control Companies formerly listed on the New York Stock Exchange Companies based in Palo Alto, California Health care companies based in California American companies established in 1948 Health care companies established in 1948 Medical technology companies of the United States Private providers of NHS services 2021 mergers and acquisitions Siemens American subsidiaries of foreign companies