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Proton Therapy
In medicine, proton therapy, or proton radiotherapy, is a type of particle therapy that uses a beam of protons to irradiate diseased tissue, most often to treat cancer. The chief advantage of proton therapy over other types of external beam radiotherapy is that the dose of protons is deposited over a narrow range of depth; hence in minimal entry, exit, or scattered radiation dose to healthy nearby tissues. When evaluating whether to treat a tumor with photon or proton therapy, physicians may choose proton therapy if it is important to deliver a higher radiation dose to targeted tissues while significantly decreasing radiation to nearby organs at risk. The American Society for Radiation Oncology Model Policy for Proton Beam therapy says proton therapy is considered reasonable if sparing the surrounding normal tissue "cannot be adequately achieved with photon-based radiotherapy" and can benefit the patient. Like photon radiation therapy, proton therapy is often used in conjunc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Particle Therapy
Particle therapy is a form of external beam radiotherapy using beams of energetic neutrons, protons, or other heavier positive ions for cancer treatment. The most common type of particle therapy as of August 2021 is proton therapy. In contrast to X-rays (photon beams) used in older radiotherapy, particle beams exhibit a Bragg peak in energy loss through the body, delivering their maximum radiation dose at or near the tumor and minimizing damage to surrounding normal tissues. Particle therapy is also referred to more technically as hadron therapy, excluding photon and electron therapy. Neutron capture therapy, which depends on a secondary nuclear reaction, is also not considered here. Muon therapy, a rare type of particle therapy not within the categories above, has also been studied theoretically; however, muons are still most commonly used for imaging, rather than therapy. Method Particle therapy works by aiming energetic ionizing particles at the target tumor. These par ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electron Volts
In physics, an electronvolt (symbol eV), also written electron-volt and electron volt, is the measure of an amount of kinetic energy gained by a single electron accelerating through an electric potential difference of one volt in vacuum. When used as a unit of energy, the numerical value of 1 eV in joules (symbol J) is equal to the numerical value of the charge of an electron in coulombs (symbol C). Under the 2019 revision of the SI, this sets 1 eV equal to the exact value Historically, the electronvolt was devised as a standard unit of measure through its usefulness in electrostatic particle accelerator sciences, because a particle with electric charge ''q'' gains an energy after passing through a voltage of ''V''. Definition and use An electronvolt is the amount of energy gained or lost by a single electron when it moves through an electric potential difference of one volt. Hence, it has a value of one volt, which is , multiplied by the elementary charge Therefore ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Synchrocyclotron
A synchrocyclotron is a special type of cyclotron, patented by Edwin McMillan in 1952, in which the frequency of the driving RF electric field is varied to compensate for relativistic effects as the particles' velocity begins to approach the speed of light. This is in contrast to the classical cyclotron, where this frequency is constant. There are two major differences between the synchrocyclotron and the classical cyclotron. In the synchrocyclotron, only one ''dee'' (hollow D-shaped sheet metal electrode) retains its classical shape, while the other pole is open (see patent sketch). Furthermore, the frequency of oscillating electric field in a synchrocyclotron is decreasing continuously instead of kept constant so as to maintain cyclotron resonance for relativistic velocities. One terminal of the oscillating electric potential varying periodically is applied to the dee and the other terminal is on ground potential. The protons or deuterons to be accelerated are made to move i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
USSR
The Union of Soviet Socialist Republics. (USSR), commonly known as the Soviet Union, was a List of former transcontinental countries#Since 1700, transcontinental country that spanned much of Eurasia from 1922 until Dissolution of the Soviet Union, it dissolved in 1991. During its existence, it was the list of countries and dependencies by area, largest country by area, extending across Time in Russia, eleven time zones and sharing Geography of the Soviet Union#Borders and neighbors, borders with twelve countries, and the List of countries and dependencies by population, third-most populous country. An overall successor to the Russian Empire, it was nominally organized as a federal union of Republics of the Soviet Union, national republics, the largest and most populous of which was the Russian SFSR. In practice, Government of the Soviet Union, its government and Economy of the Soviet Union, economy were Soviet-type economic planning, highly centralized. As a one-party state go ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Massachusetts General Hospital
Massachusetts General Hospital (Mass General or MGH) is a teaching hospital located in the West End neighborhood of Boston, Massachusetts. It is the original and largest clinical education and research facility of Harvard Medical School/Harvard University, and houses the world's largest hospital-based research program with an annual research budget of more than $1.2 billion in 2021. It is the third-oldest general hospital in the United States with a patient capacity of 999 beds. Along with Brigham and Women's Hospital, Mass General is a founding member of Mass General Brigham, formerly known as Partners HealthCare, the largest healthcare provider in Massachusetts. History Founded in 1811, the original hospital was designed by the famous American architect Charles Bulfinch. It is the third-oldest general hospital in the United States; only Pennsylvania Hospital (1751) and NewYork-Presbyterian Hospital's predecessor New York Hospital (1771) are older. John Warren, Profess ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Uppsala University
Uppsala University (UU) () is a public university, public research university in Uppsala, Sweden. Founded in 1477, it is the List of universities in Sweden, oldest university in Sweden and the Nordic countries still in operation. Initially founded in the 15th century, the university rose to significance during the rise of Swedish Empire, Sweden as a great power at the end of the 16th century and was then given relative financial stability with a large donation from Monarchy of Sweden, King Gustavus Adolphus of Sweden, Gustavus Adolphus in the early 17th century. Uppsala also has an important historical place in Swedish national culture, and national identity, identity for the Swedish establishment: in historiography, religion, literature, politics, and music. Many aspects of Swedish academic culture in general, such as the white student cap, originated in Uppsala. It shares some peculiarities, such as the student nation system, with Lund University and the University of Helsink ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Berkeley Radiation Laboratory
Lawrence Berkeley National Laboratory (LBNL, Berkeley Lab) is a federally funded research and development center in the hills of Berkeley, California, United States. Established in 1931 by the University of California (UC), the laboratory is sponsored by the United States Department of Energy and administered by the UC system. Ernest Lawrence, who won the Nobel prize for inventing the cyclotron, founded the lab and served as its director until his death in 1958. Located in the Berkeley Hills, the lab overlooks the campus of the University of California, Berkeley. Scientific research The mission of Berkeley Lab is to bring science solutions to the world. The research at Berkeley Lab has four main themes: discovery science, energy, earth systems, and the future of science. The Laboratory's 22 scientific divisions are organized within six areas of research: Computing Sciences, Physical Sciences, Earth and Environmental Sciences, Biosciences, Energy Sciences, and Energy Technologie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Particle Accelerators
A particle accelerator is a machine that uses electromagnetic fields to propel electric charge, charged particles to very high speeds and energies to contain them in well-defined particle beam, beams. Small accelerators are used for fundamental research in particle physics. Accelerators are also used as synchrotron light sources for the study of condensed matter physics. Smaller particle accelerators are used in a wide variety of applications, including particle therapy for oncology, oncological purposes, Isotopes in medicine, radioisotope production for medical diagnostics, Ion implantation, ion implanters for the manufacturing of Semiconductor, semiconductors, and Accelerator mass spectrometry, accelerator mass spectrometers for measurements of rare isotopes such as radiocarbon. Large accelerators include the Relativistic Heavy Ion Collider at Brookhaven National Laboratory in New York, and the largest accelerator, the Large Hadron Collider near Geneva, Switzerland, operated b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard Cyclotron Laboratory
The Harvard Cyclotron Laboratory operated from 1949 to 2002. It was most notable for its contributions to the development of proton therapy. The Harvard Cyclotron Laboratory was built with office of Naval Research funds between 1946 and 1949 to replace an earlier, lower energy, cyclotron that was sent to Los Alamos for use in the Manhattan Project. Richard Wilson, "A Brief History of the Harvard University Cyclotrons", Harvard University Press, 2004 Until 1961, the laboratory primarily performed experiments in physics. The lab performed research and development in particle physics (including ''particle detectors'' development and testing), activation analysis, radiobiology, and solid state physics. The use of proton particle accelerators for external beam radiotherapy was largely developed at this facility in collaboration with Massachusetts General Hospital Massachusetts General Hospital (Mass General or MGH) is a teaching hospital located in the West End neighborhood ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robert R
Robert Lee Rayford (February 3, 1953 – May 15, 1969), sometimes identified as Robert R. due to his age, was an American teenager from Missouri who has been suggested to represent the earliest confirmed case of HIV/AIDS in North America. This is based on evidence published in 1988 in which the authors claimed that medical evidence indicated that he was "infected with a virus closely related or identical to human immunodeficiency virus type 1." Rayford died of pneumonia, but his other symptoms baffled the doctors who treated him. A study published in 1988 reported the detection of antibodies against HIV. Results of testing for HIV genetic material were reported at a scientific conference in Australia in 1999. However, the data has never been published in a peer-reviewed medical or scientific journal. No photos of Rayford are known to exist. Background Robert Rayford was born on February 3, 1953, in St. Louis, Missouri. As a single parent, his mother Constance had to rais ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Linear Accelerator
A linear particle accelerator (often shortened to linac) is a type of particle accelerator that accelerates charged subatomic particles or ions to a high speed by subjecting them to a series of oscillating electric potentials along a linear beamline. The principles for such machines were proposed by Gustav Ising in 1924, while the first machine that worked was constructed by Rolf Widerøe in 1928 at the RWTH Aachen University. Linacs have many applications: they generate X-rays and high energy electrons for medicinal purposes in radiation therapy, serve as particle injectors for higher-energy accelerators, and are used directly to achieve the highest kinetic energy for light particles (electrons and positrons) for particle physics. The design of a linac depends on the type of particle that is being accelerated: electrons, protons or ions. Linacs range in size from a cathode-ray tube (which is a type of linac) to the linac at the SLAC National Accelerator Laboratory in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Synchrotron
A synchrotron is a particular type of cyclic particle accelerator, descended from the cyclotron, in which the accelerating particle beam travels around a fixed closed-loop path. The strength of the magnetic field which bends the particle beam into its closed path increases with time during the accelerating process, being ''synchronized'' to the increasing kinetic energy of the particles. The synchrotron is one of the first accelerator concepts to enable the construction of large-scale facilities, since bending, beam focusing and acceleration can be separated into different components. The most powerful modern particle accelerators use versions of the synchrotron design. The largest synchrotron-type accelerator, also the largest particle accelerator in the world, is the Large Hadron Collider (LHC) near Geneva, Switzerland, completed in 2008 by the European Organization for Nuclear Research (CERN). It can accelerate beams of protons to an energy of 7 electron volt, teraelectro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
