TBPO is an extremely toxic
bicyclic phosphate
Bicyclic phosphate is a class of organophosphate compounds that are used as flame retardants, stabilizers and antioxidants. They are also used in spectroscopic studies.
Some bicyclic phosphates, such as TBPS, TBPO and IPTBO, are highly toxic. ...
convulsant A convulsant is a drug which induces convulsions and/or epileptic seizures, the opposite of an anticonvulsant. These drugs generally act as stimulants at low doses, but are not used for this purpose due to the risk of convulsions and consequent e ...
and
GABA receptor antagonist. It is the most toxic
bicyclic phosphate
Bicyclic phosphate is a class of organophosphate compounds that are used as flame retardants, stabilizers and antioxidants. They are also used in spectroscopic studies.
Some bicyclic phosphates, such as TBPS, TBPO and IPTBO, are highly toxic. ...
known, with an of 36 μg/kg in mice.
See also
*
TBPS
TBPS (''tert''-butylbicyclophosphorothionate) is a bicyclic phosphate convulsant. It is an extremely potent GABA receptor antagonist.
See also
*IPTBO
*EBOB
EBOB is a GABA receptor antagonist and neurotoxin.
See also
* TBPS
*IPTBO
IPTBO (is ...
*
IPTBO
IPTBO (isopropylbicyclophosphate, also IPPO) is a bicyclic phosphate convulsant. It is an extremely potent GABA receptor antagonist that can cause violent convulsions in mice.
IPTBO is found among a group of highly toxic bicyclic phosphates. Ge ...
References
Convulsants
Neurotoxins
Bicyclic phosphates
GABAA receptor negative allosteric modulators
Tert-butyl compounds
{{Neurotoxin-stub