Tinea manuum is a
fungal infection
Fungal infection, also known as mycosis, is a disease caused by fungi. Different types are traditionally divided according to the part of the body affected: superficial, subcutaneous, and systemic. Superficial fungal infections include common ...
of the hand, mostly a type of
dermatophytosis
Dermatophytosis, also known as tinea and ringworm, is a fungal infection of the skin (a dermatomycosis), that may affect skin, hair, and nails. Typically it results in a red, itchy, scaly, circular rash. Hair loss may occur in the area aff ...
, often part of
two feet-one hand syndrome.
There is diffuse scaling on the palms or back of usually one hand and the palmar creases appear more prominent.
When both hands are affected, the rash looks different on each hand, with palmar creases appearing whitish if the infection has been present for a long time.
It can be itchy and look slightly raised.
Nails may also be affected.
The most common cause is ''
Trichophyton rubrum
''Trichophyton rubrum'' is a dermatophytic fungus in the phylum Ascomycota. It is an exclusively clonal, anthropophilic saprotroph that colonizes the upper layers of dead skin, and is the most common cause of athlete's foot, fungal infection of ...
''.
The infection can result from touching another area of the body with a fungal infection such as
athlete's foot
Athlete's foot, known medically as ''tinea pedis'', is a common skin infection of the feet caused by a fungus. Signs and symptoms often include itching, scaling, cracking and redness. In rare cases the skin may blister. Athlete's foot fungus ...
or
fungal infection of the groin, contact with an infected person or animal, or contact with soil or contaminated towels.
Risk factors include
diabetes
Diabetes mellitus, commonly known as diabetes, is a group of common endocrine diseases characterized by sustained high blood sugar levels. Diabetes is due to either the pancreas not producing enough of the hormone insulin, or the cells of th ...
,
high blood pressure
Hypertension, also known as high blood pressure, is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. High blood pressure usually does not cause symptoms itself. It is, however, a major ri ...
,
weak immune system, humid surroundings, excessive sweating, recurrent hand trauma and cracks in the feet.
Pet owners and farmworkers are also at higher risk.
Machine operators, mechanics, gas and electricity workers, and people who work with chemicals have also been reported to be at greater risk.
Diagnosis is by visualization, direct
microscopy
Microscopy is the technical field of using microscopes to view subjects too small to be seen with the naked eye (objects that are not within the resolution range of the normal eye). There are three well-known branches of microscopy: optical mic ...
and culture.
Psoriasis
Psoriasis is a long-lasting, noncontagious autoimmune disease characterized by patches of abnormal skin. These areas are red, pink, or purple, dry, itchy, and scaly. Psoriasis varies in severity from small localized patches to complete b ...
of the palms,
pompholyx and
contact dermatitis
Contact dermatitis is a type of acute or chronic inflammation of the skin caused by exposure to chemical or physical agents. Symptoms of contact dermatitis can include itchy or dry skin, a red rash, bumps, blisters, or swelling. These rashes ...
may appear similar.
Treatment is usually with long-term topical
antifungal medications
An antifungal medication, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis (thrush), serious systemic infections such as cry ...
.
If not resolving,
terbinafine
Terbinafine, sold under the brand name Lamisil among others, is an antifungal medication used to treat pityriasis versicolor, onychomycosis, fungal nail infections, and ringworm including jock itch and athlete's foot. It is either oral adminis ...
or
itraconazole
Itraconazole, sometimes abbreviated ITZ, is an antifungal medication used to treat a number of fungal infections. This includes aspergillosis, blastomycosis, coccidioidomycosis, histoplasmosis, and paracoccidioidomycosis. It may be given ...
taken by mouth might be options.
It occurs worldwide.
One large study revealed around 84% of tinea manuum was associated with athlete's foot, of which 80% of patients admitted scratching their feet, and 60% were male,
Signs and symptoms
There is usually an itch, with generalised dry flaky thick skin of the palm of a hand.
Frequently, one hand is affected, but it can be in both.
If the back of the hand is affected, it may appear as reddish circles like in ringworm.
Sometimes there are no symptoms.
The feet may be affected as in
two feet-one hand syndrome.
Cause
The most common cause is ''
Trichophyton rubrum
''Trichophyton rubrum'' is a dermatophytic fungus in the phylum Ascomycota. It is an exclusively clonal, anthropophilic saprotroph that colonizes the upper layers of dead skin, and is the most common cause of athlete's foot, fungal infection of ...
''.
Other causes include ''
Trichophyton verrucosum'' (from cattle), ''
Microsporum canis
''Microsporum canis'' is a pathogenic, asexual fungus in the phylum Ascomycota that infects the upper, dead layers of skin on domesticated cats, and occasionally dogs and humans. The species has a worldwide distribution.
Taxonomy and evolution
...
'' (from a cat or dog), ''
Trichophyton erinacei
''Trichophyton erinacei'' is a species in the fungal
A fungus (: fungi , , , or ; or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushroo ...
'' (from a hedgehog), ''
Trichophyton mentagrophytes
''Trichophyton mentagrophytes'' is a species in the fungal genus '' Trichophyton''. It is one of three common fungi which cause ringworm in companion animals. It is also the second-most commonly isolated fungus causing tinea infections in human ...
'', ''
Epidermophyton floccosum
''Epidermophyton floccosum'' is a filamentous fungus that causes skin and nail infections in humans. This anthropophilic dermatophyte can lead to diseases such as tinea pedis (athlete's foot), tinea cruris, tinea corporis and onychomycosis. Diag ...
'', ''
Trichophyton interdigitale'', and more rarely ''
Microsporum gypseum'', ''
Trichophyton eriotrephon
''Trichophyton'' is a genus of fungus, which includes the parasitic varieties that cause tinea, including athlete's foot, ringworm, jock itch, and similar infections of the nail, beard, skin and scalp. Trichophyton fungi are molds characterize ...
'', and ''
Arhroderma benhamiae''.
Tinea manuum can result from touching another area of the body with a fungal infection such as athlete's foot or
tinea cruris
Tinea cruris (TC), also known as jock itch, is a common type of contagious, superficial fungal infection of the groin and buttocks region, which occurs predominantly but not exclusively in men and in hot-humid climates.
Typically, over the upper ...
, contact with an infected person or animal, or from contact with soil or contaminated towels.
Risk factors
Diabetes
Diabetes mellitus, commonly known as diabetes, is a group of common endocrine diseases characterized by sustained high blood sugar levels. Diabetes is due to either the pancreas not producing enough of the hormone insulin, or the cells of th ...
,
high blood pressure
Hypertension, also known as high blood pressure, is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. High blood pressure usually does not cause symptoms itself. It is, however, a major ri ...
,
weak immune system, humid surroundings, excessive sweating, recurrent hand trauma and cracks in feet are risk factors for tinea manuum.
Pet owners and farmworkers are also at higher risk.
Diagnosis
Diagnosis is by visualization, direct microscopy and culture.
Differential diagnosis
Psoriasis
Psoriasis is a long-lasting, noncontagious autoimmune disease characterized by patches of abnormal skin. These areas are red, pink, or purple, dry, itchy, and scaly. Psoriasis varies in severity from small localized patches to complete b ...
of the palms,
pompholyx and
contact dermatitis
Contact dermatitis is a type of acute or chronic inflammation of the skin caused by exposure to chemical or physical agents. Symptoms of contact dermatitis can include itchy or dry skin, a red rash, bumps, blisters, or swelling. These rashes ...
may appear similar.
Prevention
Prevention is focused on hygiene such as washing hands, avoiding scratching the feet or touching
fungal toe infections.
Treatment
Treatment is usually with long-term topical
antifungal medications
An antifungal medication, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis (thrush), serious systemic infections such as cry ...
.
If not resolving,
terbinafine
Terbinafine, sold under the brand name Lamisil among others, is an antifungal medication used to treat pityriasis versicolor, onychomycosis, fungal nail infections, and ringworm including jock itch and athlete's foot. It is either oral adminis ...
or
itraconazole
Itraconazole, sometimes abbreviated ITZ, is an antifungal medication used to treat a number of fungal infections. This includes aspergillosis, blastomycosis, coccidioidomycosis, histoplasmosis, and paracoccidioidomycosis. It may be given ...
by mouth might be options.
Other options include
clotrimazole
Clotrimazole, sold under the brand name Lotrimin, among others, is an antifungal medication. It is used to treat vaginal yeast infections, oral thrush, diaper rash, tinea versicolor, and types of ringworm including athlete's foot and jock itc ...
,
fluconazole
Fluconazole is an antifungal medication used for a number of fungal infections. These include candidiasis, blastomycosis, coccidioidomycosis, cryptococcosis, histoplasmosis, dermatophytosis, and tinea versicolor. It is also used to pr ...
and
ketoconazole
Ketoconazole, sold under the brand name Nizoral, among others, is an antiandrogen, antifungal drug, antifungal, and antiglucocorticoid medication used to treat a number of fungal infections. Applied to the skin it is used for fungal skin inf ...
.
Epidemiology
Tinea manuum is most common in young adult males.
Dermatophyte
Dermatophyte (from Greek '' derma'' "skin" ( GEN ''dermatos'') and ''phyton'' "plant") is a common label for a group of fungus of '' Arthrodermataceae'' that commonly causes skin disease in animals and humans. Traditionally, these anamorphic ( ...
infections occur in up to a quarter of the world's population, of which the hands and feet are most commonly involved.
It occurs worldwide.
One large study revealed around 84% of tinea manuum was associated with athlete's foot, of which 80% admitted scratching their feet, and 60% were male,
See also
*
List of cutaneous conditions
Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the Human body, body and composed of Human skin, skin, hair, Nail (anatomy), nails, and related muscle and glands. The major function o ...
References
External links
{{Diseases of the skin and appendages by morphology
Mycosis-related cutaneous conditions