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Tinea Cruris
Tinea cruris (TC), also known as jock itch, is a common type of contagious, superficial fungal infection of the groin and buttocks region, which occurs predominantly but not exclusively in men and in hot-humid climates. Typically, over the upper inner thighs, there is an intensely itchy red raised rash with a scaly well-defined curved border. It is often associated with athlete's foot and fungal nail infections, excessive sweating, and sharing of infected towels or sports clothing. It is uncommon in children. Its appearance may be similar to some other rashes that occur in skin folds including candidal intertrigo, erythrasma, inverse psoriasis and seborrhoeic dermatitis. Tests may include microscopy and culture of skin scrapings. Treatment is with topical antifungal medications and is particularly effective if symptoms have recent onset. Prevention of recurrences include treating concurrent fungal infections and taking measures to avoid moisture build-up including keeping the ...
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Dermatology
Dermatology is the branch of medicine dealing with the Human skin, skin.''Random House Webster's Unabridged Dictionary.'' Random House, Inc. 2001. Page 537. . It is a speciality with both medical and surgical aspects. A List of dermatologists, dermatologist is a specialist medical doctor who manages diseases related to skin. Etymology Attested in English in 1819, the word "dermatology" derives from the Ancient Greek, Greek δέρματος (''dermatos''), genitive of δέρμα (''derma''), "skin" (itself from δέρω ''dero'', "to flay") and -λογία ''wikt:-logia, -logia''. Neo-Latin ''dermatologia'' was coined in 1630, an anatomical term with various French and German uses attested from the 1730s. History In 1708, the first great school of dermatology became a reality at the famous Hôpital Saint-Louis in Paris, and the first textbooks (Willan's, 1798–1808) and atlases (Jean-Louis-Marc Alibert, Alibert's, 1806–1816) appeared in print around the same time.Freedber ...
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Papules
A papule is a small, well-defined bump in the skin. It may have a rounded, pointed or flat top, and may have a dip. It can appear with a stalk, be thread-like or look warty. It can be soft or firm and its surface may be rough or smooth. Some have crusts or scales. A papule can be flesh colored, yellow, white, brown, red, blue or purplish. There may be just one or many, and they may occur irregularly in different parts of the body or appear in clusters. It does not contain fluid but may progress to a pustule or vesicle. A papule is smaller than a nodule; it can be as tiny as a pinhead and is typically less than 1 cm in width, according to some sources, and 0.5 cm according to others. When merged together, it appears as a plaque. A papule's colour might indicate its cause, such as white in milia, red in eczema, yellowish in xanthoma and black in melanoma. They may open when scratched and become infected and crusty. Definition A papule is a small, well-defined ...
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Trichophyton Mentagrophytes
''Trichophyton mentagrophytes'' is a species in the fungal genus '' Trichophyton''. It is one of three common fungi which cause ringworm in companion animals. It is also the second-most commonly isolated fungus causing tinea infections in humans, and the most common or one of the most common fungi that cause zoonotic skin disease. ''Trichophyton mentagrophytes'' is frequently isolated from dogs, cats, rabbits, guinea pigs and other rodents, though at least some genetic variants possess the potential of human-to-human transmission, e.g. Type VII and Type VIII. As of 2024 it is an emerging STD in men who have sex with men and in sex workers of all genders. Nomenclature Along with closely related '' T. interdigitale'', the species has been traditionally treated as a part of polyphyletic assemblage, named "''T. mentagrophytes'' sensu lato". From 1999 to 2017 the two species have been collectively referred to as ''T. interdigitale'', while the name "''T. mentagrophytes''" has been ...
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Epidermophyton Floccosum
''Epidermophyton floccosum'' is a filamentous fungus that causes skin and nail infections in humans. This anthropophilic dermatophyte can lead to diseases such as tinea pedis (athlete's foot), tinea cruris, tinea corporis and onychomycosis. Diagnostic approaches of the fungal infection include physical examination, culture testing, and molecular detection. Topical antifungal treatment, such as the use of terbinafine, itraconazole, voriconazole, and ketoconazole, is often effective. ''E. floccosum'' is one of the 2 species in the genus '' Epidermophyton''. During the 20th century, this species was the fourth most common cause of dermatophytosis in North America. This ascomycete has a worldwide distribution but is more commonly isolated from patients in tropical and subtropical areas. The non-soil associated fungus has no specific growth conditions and shows characteristic smooth club-shaped macroconidia under the microscope. History and taxonomy The fungus was first isolated in ...
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Trichophyton Rubrum
''Trichophyton rubrum'' is a dermatophytic fungus in the phylum Ascomycota. It is an exclusively clonal, anthropophilic saprotroph that colonizes the upper layers of dead skin, and is the most common cause of athlete's foot, fungal infection of nail, jock itch, and ringworm worldwide. ''Trichophyton rubrum'' was first described by in 1845 and is currently considered to be a complex of species that comprises multiple, geographically patterned morphotypes, several of which have been formally described as distinct taxa, including ''T. raubitschekii'', ''T. gourvilii'', ''T. megninii'' and ''T. soudanense''. Growth and morphology Typical isolates of ''T. rubrum'' are white and cottony on the surface. The colony underside is usually red, although some isolates appear more yellowish and others more brownish. ''Trichophyton rubrum'' grows slowly in culture with sparse production of teardrop or peg-shaped microconidia laterally on fertile hyphae. Macroconidia, when present, are smoot ...
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Macroconidia Of Epidermophyton Floccosum (PHIL 4207 Lores)
A conidium ( ; : conidia), sometimes termed an asexual chlamydospore or chlamydoconidium (: chlamydoconidia), is an asexual, non-motile spore of a fungus. The word ''conidium'' comes from the Ancient Greek word for dust, ('). They are also called mitospores due to the way they are generated through the cellular process of mitosis. They are produced exogenously. The two new haploid cells are genetically identical to the haploid parent, and can develop into new organisms if conditions are favorable, and serve in biological dispersal. Asexual reproduction in ascomycetes (the phylum Ascomycota) is by the formation of conidia, which are borne on specialized stalks called conidiophores. The morphology of these specialized conidiophores is often distinctive between species and, before the development of molecular techniques at the end of the 20th century, was widely used for identification of (''e.g.'' ''Metarhizium'') species. The terms microconidia and macroconidia are sometimes ...
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Pruritus Ani
Pruritus ani is the irritation of the skin at the exit of the rectum, known as the anus, causing the desire to scratch. The intensity of anal itching increases from moisture, pressure, and rubbing caused by clothing and sitting. At worst, anal itching causes intolerable discomfort that often is accompanied by burning and soreness. It is estimated that up to 5% of the population of the United States experiences this type of discomfort daily. Causes If a specific cause for pruritus ani is found it is classified as "secondary pruritus ani". If a specific cause is ''not'' found it is classified as "idiopathic pruritus ani". The irritation can be caused by intestinal parasites, anal perspiration, frequent liquid stools, diarrhea, residual stool deposits, or the escape of small amounts of stool as a result of incontinence or flatulence. Another cause is yeast infection or candidiasis. Some diseases increase the possibility of yeast infections, such as diabetes mellitus or HIV infection. ...
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Steroids
A steroid is an organic compound with four fused rings (designated A, B, C, and D) arranged in a specific molecular configuration. Steroids have two principal biological functions: as important components of cell membranes that alter membrane fluidity; and as signaling molecules. Examples include the lipid cholesterol, sex hormones estradiol and testosterone, anabolic steroids, and the anti-inflammatory corticosteroid drug dexamethasone. Hundreds of steroids are found in fungi, plants, and animals. All steroids are manufactured in cells from a sterol: cholesterol (animals), lanosterol ( opisthokonts), or cycloartenol (plants). All three of these molecules are produced via cyclization of the triterpene squalene. Structure The steroid nucleus ( core structure) is called gonane (cyclopentanoperhydrophenanthrene). It is typically composed of seventeen carbon atoms, bonded in four fused rings: three six-member cyclohexane rings (rings A, B and C in the first illus ...
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Immunodeficiency
Immunodeficiency, also known as immunocompromise, is a state in which the immune system's ability to fight infectious diseases and cancer is compromised or entirely absent. Most cases are acquired ("secondary") due to extrinsic factors that affect the patient's immune system. Examples of these extrinsic factors include HIV infection and environmental factors, such as nutrition. Immunocompromisation may also be due to genetic diseases/flaws such as SCID. In clinical settings, immunosuppression by some drugs, such as steroids, can either be an adverse effect or the intended purpose of the treatment. Examples of such use is in organ transplant surgery as an anti- rejection measure and in patients with an overactive immune system, as in autoimmune diseases. Some people are born with intrinsic defects in their immune system, or primary immunodeficiency. A person who has an immunodeficiency of any kind is said to be immunocompromised. An immunocompromised individual may par ...
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Human Penis
In Human body, human anatomy, the penis (; : penises or penes; from the Latin ''pēnis'', initially 'tail') is an external sex organ (intromittent organ) through which males urination, urinate and ejaculation, ejaculate, as Penis, on other animals. Together with the testes and surrounding structures, the penis functions as part of the male reproductive system. The main parts of the penis are the Root of penis, root, Body of penis, body, the epithelium of the penis, including the shaft skin, and the foreskin covering the glans penis, glans. The body of the penis is made up of three columns of tissue (biology), tissue: two Corpus cavernosum penis, corpora cavernosa on the dorsal side and corpus spongiosum penis, corpus spongiosum between them on the ventral side. The Urethra#Male, urethra passes through the prostate gland, where it is joined by the ejaculatory ducts, and then through the penis. The urethra goes across the corpus spongiosum and ends at the tip of the glans as the o ...
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Mons Pubis
In human anatomy, and in mammals in general, the ''mons pubis'' or pubic mound (also known simply as the mons , and known specifically in females as the ''mons Venus'' or ''mons veneris'') is a rounded mass of fatty tissue found over the pubic symphysis of the pubic bones. Structure For females, the ''mons pubis'' forms the anterior and superior portion of the vulva. It divides into the labia majora (literally "larger lips"), on either side of the furrow known as the ''pudendal cleft'' that surrounds the rest of the vulvar parts: labia minora, clitoris, urinary meatus, vaginal opening, and vulval vestibule. Although present in both men and women, the ''mons pubis'' tends to be larger in women. Its fatty tissue is sensitive to estrogen, causing a distinct mound to form with the onset of female puberty. This pushes the forward portion of the labia majora out and away from the pubic bone. The mound also becomes covered with pubic hair. It often becomes less prominent with th ...
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Labia Majora
In primates, and specifically in humans, the labia majora (: labium majus), also known as the outer lips or outer labia, are two prominent Anatomical terms of location, longitudinal skin folds that extend downward and backward from the mons pubis to the perineum. Together with the labia minora, they form the labia of the vulva. The labia majora are Homology (biology), homologous to the male scrotum. Etymology ''Labia majora'' is the Latin plural for big ("major") lips. The Latin term ''labium/labia'' is used in anatomy for a number of usually paired parallel structures, but in English, it is mostly applied to two pairs of parts of the vulva—labia majora and labia minora. Traditionally, to avoid confusion with other lip-like structures of the body, the vulvar labia were termed by anatomists in Latin as ''labia majora (''or ''minora) pudendi.'' Embryology Embryologically, they develop from labioscrotal folds. The labia majora after puberty may become of a darker color than the ...
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