Secoergoline
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Secoergoline is an analogue of
ergoline Ergoline is a core structure in many alkaloids and their synthetic derivatives. Ergoline alkaloids were first characterized in ergot. Some of these are implicated in the condition of ergotism, which can take a convulsive form or a gangrenous for ...
with one or more bonds removed and may refer to: *
3,5-Secoergoline RU-27251, also known as 3,5-secoergoline or as 4-piperidin-3-yl-1''H''-indole, is a serotonin receptor modulator and dopamine receptor agonist of the partial ergoline family. Its affinity (KD) for the dopamine D2high receptor was 72nM and for th ...
(also known as RU-27251) * 8,10-Secoergoline (e.g.,
8,10-seco-LSD NDTDI, also known as 8,10-seco-LSD, is a tricyclic tryptamine derivative which is thought to act as a serotonin receptor agonist, though its pharmacology has not been studied in detail. It is a structurally simplified analogue of the psychedeli ...
also known as NDTDI) * 10,11-Secoergoline (e.g.,
10,11-seco-LSD 10,11-Seco-LSD is a partial lysergamide and cyclized tryptamine related to lysergic acid diethylamide (LSD). It is the seco structural analog, analogue of LSD in which the covalent bond, bond between the 10 and 11 positions of the ergoline ring s ...
,
CT-5252 CT-5252 is a substituted tryptamine, tryptamine-like non-rigid structure, less-rigid structural analogue, analogue of lysergic acid diethylamide (LSD). It is a 10,11-secoergoline; that is, an substituted ergoline, ergoline in which the covalent b ...
) Other secoergolines include partial
clavine Ergoline is a core structure in many alkaloids and their synthetic derivatives. Ergoline alkaloids were first characterized in ergot. Some of these are implicated in the condition of ergotism, which can take a convulsive form or a gangrenous for ...
s like chanoclavine and paliclavine.


See also

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Seco-LSD Seco-LSD is an structural analog, analogue of LSD with one or more covalent bond, bonds removed and may refer to: * 3,5-Seco-LSD (also known as DEIMDHPCA) * 8,10-Seco-LSD (also known as NDTDI) * 10,11-Seco-LSD Additional seco-LSD compounds with mo ...
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Partial ergoline Partial or simplified ergolines and lysergamides are structural analog, analogues of ergolines and substituted lysergamide, lysergamides like LSD in which one or more atoms or covalent bond, bonds, for instance within the ergoline ring system (ch ...
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Ergoline Ergoline is a core structure in many alkaloids and their synthetic derivatives. Ergoline alkaloids were first characterized in ergot. Some of these are implicated in the condition of ergotism, which can take a convulsive form or a gangrenous for ...
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Secosteroid A secosteroid () is a type of steroid with a "broken" ring. The word ''secosteroid ''derives from the Latin verb ''secare'' meaning "to cut", and 'steroid'. Secosteroids are described as a subclass of steroids under the IUPAC nomenclature. Some ...
{{Chemistry index Partial ergolines