Eckol is a
phlorotannin isolated from brown algae in the family
Lessoniaceae
Lessoniaceae are a family of kelp. Species of this family have a transition zone with the intercalary meristem subdivided so that there are a number of secondary stipes in addition to the primary Stipe (botany), stipe.
Genera and species
*''Eckl ...
such as species in the genus ''
Ecklonia''
such as ''
E. cava''
or ''
E. kurome''
or in the genus ''
Eisenia'' such as ''
Eisenia bicyclis''.
The molecule possesses a
dibenzo-''p''-dioxin skeleton and a
phloroglucinol
Phloroglucinol is an organic compound with the formula C6H3(OH)3. It is a colorless solid. It is used in the organic synthesis, synthesis of pharmaceuticals and explosives. Phloroglucinol is one of three isomeric benzenetriols. The other two isom ...
component. The molecule can also be viewed as a phloroglucinol
trimer.
It exhibits an
antiplasmin inhibitory effect
[ and a radioprotective effect in a mouse model.]in vitro
''In vitro'' (meaning ''in glass'', or ''in the glass'') Research, studies are performed with Cell (biology), cells or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in ...
'' cytoprotective effect against oxidative stress in Chinese hamster lung fibroblasts.[ It also shows ]antithrombotic
An antithrombotic agent is a drug that reduces the formation of blood clots ( thrombi).http://cancerweb.ncl.ac.uk/cgi-bin/omd?antithrombotic Antithrombotics can be used therapeutically for prevention ( primary prevention, secondary prevention) or ...
and profibrinolytic activities.[
]
References
{{phlorotannin
Phlorotannins
Dibenzodioxins