Chondromyxoid fibroma is a rare type of
cartilage tumor which rarely occurs in the
skull
The skull, or cranium, is typically a bony enclosure around the brain of a vertebrate. In some fish, and amphibians, the skull is of cartilage. The skull is at the head end of the vertebrate.
In the human, the skull comprises two prominent ...
or
skull base
The base of skull, also known as the cranial base or the cranial floor, is the most Anatomical terms of location#Superior and inferior, inferior area of the human skull, skull. It is composed of the endocranium and the lower parts of the Calvaria ...
.
Most cases are characterised by
GRM1
The glutamate receptor, metabotropic 1, also known as GRM1, is a human gene which encodes the metabotropic glutamate receptor 1 (mGluR1) protein.
Function
L-Glutamate is the major excitatory neurotransmitter in the central nervous system and ...
gene fusion or promoter swapping.
It can be associated with a
translocation at t(1;5)(p13;p13).
References
External links
Osseous and chondromatous neoplasia
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