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Vomitoxin
Vomitoxin, also known as deoxynivalenol (DON), is a type B trichothecene, an epoxy-sesquiterpenoid. This mycotoxin occurs predominantly in grains such as wheat, barley, oats, rye, and corn, and less often in rice, sorghum, and triticale. The occurrence of deoxynivalenol is associated primarily with ''Fusarium graminearum'' (''Gibberella zeae'') and '' F. culmorum'', both of which are important plant pathogens which cause fusarium head blight in wheat and gibberella or fusarium ear blight in corn. The incidence of fusarium head blight is strongly associated with moisture at the time of flowering (anthesis), and the timing of rainfall, rather than the amount, is the most critical factor. However, increased amount of moisture towards harvest time has been associated with lower amount of vomitoxin in wheat grain due to leaching of toxins. Furthermore, deoxynivalenol contents are significantly affected by the susceptibility of cultivars towards ''Fusarium'' species, previous crop, till ...
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Fusarium Graminearum
''Gibberella zeae'', also known by the name of its anamorph ''Fusarium graminearum'', is a fungal plant pathogen which causes fusarium head blight (FHB), a devastating disease on wheat and barley. The pathogen is responsible for billions of dollars in economic losses worldwide each year. Infection causes shifts in the amino acid composition of wheat, resulting in shriveled kernels and contaminating the remaining grain with mycotoxins, mainly deoxynivalenol (DON), which inhibits protein biosynthesis; and zearalenone, an estrogenic mycotoxin. These toxins cause vomiting, liver damage, and reproductive defects in livestock, and are harmful to humans through contaminated food. Despite great efforts to find resistance genes against ''F. graminearum'', no completely resistant variety is currently available. Research on the biology of ''F. graminearum'' is directed towards gaining insight into more details about the infection process and reveal weak spots in the life cycle of this path ...
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Nivalenol
Nivalenol (NIV) is a mycotoxin of the trichothecene group. In nature it is mainly found in fungi of the ''Fusarium'' species. The ''Fusarium'' species belongs to the most prevalent mycotoxin producing fungi in the temperate regions of the northern hemisphere, therefore making them a considerable risk for the food crop production industry. The fungi are abundant in various agricultural products (cereal crops) and their further processed products (malt, beer and bread). "The ''Fusarium'' species invade and grow on crops, and may produce nivalenol under moist and cool conditions". In pigs, the symptoms observed after nivalenol exposure are "feed refusal, vomiting, gastroenteric and dermal irritation or necrosis and immunological dysfunction", as well as haematotoxicity, resulting in a low leukocyte count. History In the period of 1946 to 1963, several cases of intoxication due to the ingestion of ''Fusarium'' infected grains (scrabby grain disease) were reported in Japan, Korea ...
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Trichothecenes
Trichothecenes constitute a large group of chemically related mycotoxins. They are produced by Fungus, fungi of the genera ''Fusarium'', ''Myrothecium'', ''Trichoderma'', ''Podostroma'', ''Trichothecium'', ''Cephalosporium'', ', ''Stachybotrys'' (most in Hypocreales) and possibly others. Chemically, trichothecenes are a class of sesquiterpenes. All trichothecenes share the Cyclic compound, cyclic sesquiterpene structure but differ in the type of functional group attached to the carbon backbone. They are produced on many different grains such as wheat, Oat, oats, or maize by various ''Fusarium'' species including ''Gibberella zeae, F. graminearum'', ''Fusarium sporotrichioides, F. sporotrichioides'', ''F. poae,'' and ''Fusarium equiseti, F. equiseti''. Some moulds that produce trichothecene mycotoxins, such as ''Stachybotrys chartarum'', can grow in damp indoor environments. It has been found that macrocyclic trichothecenes produced by ''Stachybotrys chartarum, S. chartarum'' can ...
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Fusarium Ear Blight
Fusarium ear blight (FEB) (also called Fusarium head blight, FHB, or scab), is a fungus, fungal disease of cereals, including wheat, barley, oats, rye and triticale. FEB is caused by a range of ''Fusarium'' fungi, which infects the heads of the crop, reducing grain yield. The disease is often associated with contamination by mycotoxins produced by the fungi already when the crop is growing in the field. The disease can cause severe economic losses as mycotoxin-contaminated grain cannot be sold for food or feed. Causal organism Fusarium ear blight is caused by several species of ''Fusarium'' fungi, belonging to the Ascomycota. The most common species causing FEB are: * ''Gibberella avenacea, Fusarium avenaceum'' (Teleomorph, anamorph and holomorph, teleomorph: ''Gibberella avenacea'') * ''Fusarium culmorum'' * ''Gibberella zeae, Fusarium graminearum'' (teleomorph: ''Gibberella zeae'') * ''Fusarium poae'' * ''Microdochium nivale'' (teleomorph: ''Monographella nivalis'', formerly ''Fu ...
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Trichothecene
Trichothecenes constitute a large group of chemically related mycotoxins. They are produced by Fungus, fungi of the genera ''Fusarium'', ''Myrothecium'', ''Trichoderma'', ''Podostroma'', ''Trichothecium'', ''Cephalosporium'', ', ''Stachybotrys'' (most in Hypocreales) and possibly others. Chemically, trichothecenes are a class of sesquiterpenes. All trichothecenes share the Cyclic compound, cyclic sesquiterpene structure but differ in the type of functional group attached to the carbon backbone. They are produced on many different grains such as wheat, Oat, oats, or maize by various ''Fusarium'' species including ''Gibberella zeae, F. graminearum'', ''Fusarium sporotrichioides, F. sporotrichioides'', ''F. poae,'' and ''Fusarium equiseti, F. equiseti''. Some moulds that produce trichothecene mycotoxins, such as ''Stachybotrys chartarum'', can grow in damp indoor environments. It has been found that macrocyclic trichothecenes produced by ''Stachybotrys chartarum, S. chartarum'' can ...
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Byproduct
A by-product or byproduct is a secondary product derived from a production process, manufacturing process or chemical reaction; it is not the primary product or service being produced. A by-product can be useful and marketable or it can be considered waste: for example, bran, which is a byproduct of the milling of wheat into refined flour, is sometimes composted or burned for disposal, but in other cases, it can be used as a nutritious ingredient in human food or animal feed. Gasoline was once a byproduct of oil refining that later became a desirable commercial product as motor fuel. The plastic used in plastic shopping bags also started as a by-product of oil refining. By-products are sometimes called co-products to indicate that although they are secondary, they are desired products. For example, hides and leather may be called co-products of beef production. There is no strict distinction between by-products and co-products. In economics In the context of production, a ...
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Parts Per Million
In science and engineering, the parts-per notation is a set of pseudo-units to describe the small values of miscellaneous dimensionless quantity, dimensionless quantities, e.g. mole fraction or mass fraction (chemistry), mass fraction. Since these fraction (mathematics), fractions are quantity-per-quantity measures, they are pure numbers with no associated units of measurement. Commonly used are * parts-per-million - ppm, * parts-per-billion - ppb, * parts-per-trillion - ppt, * parts-per-quadrillion - ppq, This notation is not part of the International System of Units - SI system and its meaning is ambiguous. Applications Parts-per notation is often used describing dilute solutions in chemistry, for instance, the relative abundance of dissolved minerals or pollutants in water. The quantity "1 ppm" can be used for a mass fraction if a water-borne pollutant is present at one-millionth of a gram per gram of sample solution. When working with aqueous solutions, it is ...
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Poultry
Poultry () are domesticated birds kept by humans for the purpose of harvesting animal products such as meat, Eggs as food, eggs or feathers. The practice of animal husbandry, raising poultry is known as poultry farming. These birds are most typically members of the superorder Galloanserae (fowl), especially the order Galliformes (which includes chickens, quails, and domestic turkey, turkeys). The term also includes waterfowls of the family Anatidae (ducks and geese) but does not include wild birds hunted for food known as game (hunting), game or wild meat, quarry. Recent genomic studies involving the four extant junglefowl species reveals that the domestication of chicken, the most populous poultry species, occurred around 8,000 years ago in Southeast Asia. This was previously believed to have occurred around 5,400 years ago, also in Southeast Asia. The process may have originally occurred as a result of people hatching and rearing young birds from eggs collected from the wild, ...
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Aflatoxin
Aflatoxins are various toxicity, poisonous carcinogens and mutagens that are produced by certain Mold (fungus), molds, especially ''Aspergillus'' species such as ''Aspergillus flavus'' and ''Aspergillus parasiticus''. According to the USDA, "They are probably the best known and most intensively researched mycotoxins in the world." The fungi grow in soil, decaying vegetation and various staple food, staple foodstuffs and commodities such as hay, maize (corn), peanuts, coffee, wheat, millet, sorghum, cassava, rice, chili peppers, cottonseed, tree nuts, sesame seeds, sunflower seeds, and various cereal grains and oil seeds. In short, the relevant fungi grow on almost any crop or food. When such contaminated food is processed or consumed, the aflatoxins enter the general food supply. They have been found in both pet and human foods, as well as in feedstocks for agricultural animals. Animals fed contaminated food can pass aflatoxin transformation products into milk, milk products, and ...
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Carcinogen
A carcinogen () is any agent that promotes the development of cancer. Carcinogens can include synthetic chemicals, naturally occurring substances, physical agents such as ionizing and non-ionizing radiation, and biologic agents such as viruses and bacteria. Most carcinogens act by creating mutations in DNA that disrupt a cell's normal processes for regulating growth, leading to uncontrolled cellular proliferation. This occurs when the cell's DNA repair processes fail to identify DNA damage allowing the defect to be passed down to daughter cells. The damage accumulates over time. This is typically a multi-step process during which the regulatory mechanisms within the cell are gradually dismantled allowing for unchecked cellular division. The specific mechanisms for carcinogenic activity is unique to each agent and cell type. Carcinogens can be broadly categorized, however, as activation-dependent and activation-independent which relate to the agent's ability to engage dir ...
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Beef
Beef is the culinary name for meat from cattle (''Bos taurus''). Beef can be prepared in various ways; Cut of beef, cuts are often used for steak, which can be cooked to varying degrees of doneness, while trimmings are often Ground beef, ground or minced, as found in most hamburgers. Beef contains protein, iron, and vitamin B12. Along with other kinds of red meat, high consumption is associated with an increased risk of colorectal cancer and coronary heart disease, especially when processed meat, processed. Beef has a high Environmental impact of meat production, environmental impact, being a primary driver of deforestation with the highest greenhouse gas emissions of any agricultural product. In prehistoric times, humans hunted aurochs and later domesticated them. Since that time, numerous beef cattle, breeds of cattle have been Selective breeding, bred specifically for the quality or quantity of their meat. Today, beef is the third most widely consumed meat in the world, aft ...
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