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Stochastic Resonance
Stochastic resonance (SR) is a behavior of non-linear systems where random (stochastic) fluctuations in the micro state cause deterministic changes in the macro state. This occurs when the non-linear nature of the system amplifies certain (resonant) portions of the fluctuations, while not amplifying other portions of the noise. Information theory In information theory, SR can be used to reveal weak signals. When a signal that is normally too weak to be detected by a sensor can be boosted by adding white noise to the signal, which contains a wide spectrum of frequencies. The frequencies in the white noise corresponding to the original signal's frequencies will resonate with each other, amplifying the original signal while not amplifying the rest of the white noise – thereby increasing the signal-to-noise ratio, which makes the original signal more prominent. Further, the added white noise can be enough to be detectable by the sensor, which can then filter it out to effectiv ...
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White Noise
In signal processing, white noise is a random signal having equal intensity at different frequencies, giving it a constant power spectral density. The term is used with this or similar meanings in many scientific and technical disciplines, including physics, acoustical engineering, telecommunications, and statistical forecasting. White noise refers to a statistical model for signals and signal sources, not to any specific signal. White noise draws its name from white light, although light that appears white generally does not have a flat power spectral density over the visible band. In discrete time, white noise is a discrete signal whose samples are regarded as a sequence of serially uncorrelated random variables with zero mean and finite variance; a single realization of white noise is a random shock. In some contexts, it is also required that the samples be independent and have identical probability distribution (in other words independent and identically distribu ...
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Signal Processing
Signal processing is an electrical engineering subfield that focuses on analyzing, modifying and synthesizing ''signals'', such as audio signal processing, sound, image processing, images, Scalar potential, potential fields, Seismic tomography, seismic signals, Altimeter, altimetry processing, and scientific measurements. Signal processing techniques are used to optimize transmissions, Data storage, digital storage efficiency, correcting distorted signals, improve subjective video quality, and to detect or pinpoint components of interest in a measured signal. History According to Alan V. Oppenheim and Ronald W. Schafer, the principles of signal processing can be found in the classical numerical analysis techniques of the 17th century. They further state that the digital refinement of these techniques can be found in the digital control systems of the 1940s and 1950s. In 1948, Claude Shannon wrote the influential paper "A Mathematical Theory of Communication" which was publis ...
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Mutual Coherence (linear Algebra)
In linear algebra, mutual coherence (or simply coherence) measures the maximum similarity between any two columns of a matrix, defined as the largest absolute value of their cross-correlations. First explored by David Donoho and Xiaoming Huo in the late 1990s for pairs of orthogonal bases, it was later expanded by Donoho and Michael Elad in the early 2000s to study sparse representations—where signals are built from a few key components in a larger set. In signal processing, mutual coherence is widely used to assess how well algorithms like matching pursuit and basis pursuit can recover a signal’s sparse representation from a collection with extra building blocks, known as an overcomplete dictionary. Joel Tropp extended this idea with the Babel function, which applies coherence from one column to a group, equaling mutual coherence for two columns while broadening its use for larger sets with any number of columns. Formal definition Formally, let a_1, \ldots, a_m\in ^d ...
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Gaussian Noise
Carl Friedrich Gauss (1777–1855) is the eponym of all of the topics listed below. There are over 100 topics all named after this German mathematician and scientist, all in the fields of mathematics, physics, and astronomy. The English eponymous adjective ''Gaussian'' is pronounced . Mathematics Algebra and linear algebra Geometry and differential geometry Number theory Cyclotomic fields *Gaussian period *Gaussian rational *Gauss sum, an exponential sum over Dirichlet characters **Elliptic Gauss sum, an analog of a Gauss sum **Quadratic Gauss sum Analysis, numerical analysis, vector calculus and calculus of variations Complex analysis and convex analysis *Gauss–Lucas theorem *Gauss's continued fraction, an analytic continued fraction derived from the hypergeometric functions *Gauss's test, Gauss's criterion – described oEncyclopedia of Mathematics*Gauss's hypergeometric theorem, an identity on hypergeometric series *Gauss plane Statistics *Gaus ...
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Detection Limit
The limit of detection (LOD or LoD) is the lowest signal, or the lowest corresponding quantity to be determined (or extracted) from the signal, that can be observed with a sufficient degree of confidence or statistical significance. However, the exact threshold (level of decision) used to decide when a signal significantly emerges above the continuously fluctuating background noise remains arbitrary and is a matter of policy and often of debate among scientists, statisticians and regulators depending on the stakes in different fields. Significance in analytical chemistry In analytical chemistry, the detection limit, lower limit of detection, also termed LOD for limit of detection or analytical sensitivity (not to be confused with statistical sensitivity), is the lowest quantity of a substance that can be distinguished from the absence of that substance (a '' blank value'') with a stated confidence level (generally 99%). The detection limit is estimated from the mean of the blan ...
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Analog-to-digital Converter
In electronics, an analog-to-digital converter (ADC, A/D, or A-to-D) is a system that converts an analog signal, such as a sound picked up by a microphone or light entering a digital camera, into a Digital signal (signal processing), digital signal. An ADC may also provide an isolated measurement such as an electronic device that converts an analog input voltage or Electric current, current to a digital number representing the magnitude of the voltage or current. Typically the digital output is a two's complement binary number that is proportional to the input, but there are other possibilities. There are several ADC hardware architecture, architectures. Due to the complexity and the need for precisely matched electronic component, components, all but the most specialized ADCs are implemented as integrated circuits (ICs). These typically take the form of metal–oxide–semiconductor (MOS) mixed-signal integrated circuit chips that integrate both Analogue electronics, anal ...
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Dither
Dither is an intentionally applied form of noise used to randomize quantization error, preventing large-scale patterns such as color banding in images. Dither is routinely used in processing of both digital audio and video data, and is often one of the last stages of mastering audio to a CD. A common use of dither is converting a grayscale image to black and white, so that the density of black dots in the new image approximates the average gray level in the original. Etymology The term ''dither'' was published in books on analog computation and hydraulically controlled guns shortly after World War II. Though he did not use the term ''dither'', the concept of dithering to reduce quantization patterns was first applied by Lawrence G. Roberts in his 1961 MIT master's thesis and 1962 article. By 1964 dither was being used in the modern sense described in this article. The technique was in use at least as early as 1915, though not under the name ''dither''. In digital pro ...
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James Collins (bioengineer)
James J. Collins (born June 26, 1965) is an American biomedical engineer and bioengineer who serves as the Termeer Professor of Medical Engineering & Science at the Massachusetts Institute of Technology (MIT), where he is also a director at the MIT Jameel Clinic, MIT Abdul Latif Jameel Clinic for Machine Learning in Health. Collins conducted research showing that artificial intelligence (AI) approaches can be used to discover novel antibiotics, such as halicin and abaucin. He serves as the director of the Antibiotics-AI Project at MIT, which is supported by The Audacious Project, and is a member of the Harvard–MIT Program in Health Sciences and Technology. He is also a core faculty member at the Wyss Institute for Biologically Inspired Engineering at Harvard University and a member of the Broad Institute. Collins is one of the founders of the field of synthetic biology, and his work on synthetic gene circuits and programmable cells has led to the development of new classes o ...
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Synaptic Noise
Synaptic noise refers to the constant bombardment of synaptic activity in neurons. This occurs in the background of a cell when potentials are produced without the nerve stimulation of an action potential, and are due to the inherently random nature of synapses. These random potentials have similar time courses as excitatory postsynaptic potentials (EPSPs) and inhibitory postsynaptic potentials (IPSPs), yet they lead to variable neuronal responses. The variability is due to differences in the discharge times of action potentials. Causes Many types of noise exist in cells. First, there is intrinsic noise and extrinsic, or synaptic, noise. Within each category there are two further divisions of noise – voltage noise or temporal noise. Intrinsic voltage noise is due to random changes in the membrane potential of a cell, and intrinsic temporal noise is caused by variations in spike generation timing. The following sections give explanations about the causes of synaptic noise. Quant ...
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Squid Giant Axon
The squid giant axon is the very large (up to 1.5 mm in diameter; typically around 0.5 mm) axon that controls part of the water jet propulsion system in squid. It was first described by L. W. Williams in 1909, but this discovery was forgotten until English zoologist and neurophysiologist J. Z. Young demonstrated the axon's function in the 1930s while working in the Stazione Zoologica in Naples, the Marine Biological Association in Plymouth and the Marine Biological Laboratory in Woods Hole. Squids use this system primarily for making brief but very fast movements through the water. On the underside of the squid's body, between the head and the mantle, is a siphon through which water can be rapidly expelled by the fast contractions of the body wall muscles of the animal. This contraction is initiated by action potentials in the giant axon. Action potentials travel faster in an axon with a large diameter than a smaller one, and squid have evolved the giant axon ...
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Purkinje Cells
Purkinje cells or Purkinje neurons, named for Czech physiologist Jan Evangelista Purkyně who identified them in 1837, are a unique type of prominent, large neuron located in the cerebellar cortex of the brain. With their flask-shaped cell bodies, many branching dendrites, and a single long axon, these cells are essential for controlling motor activity. Purkinje cells mainly release GABA (gamma-aminobutyric acid) neurotransmitter, which inhibits some neurons to reduce nerve impulse transmission. Purkinje cells efficiently control and coordinate the body's motor motions through these inhibitory actions. Structure These cells are some of the largest neurons in the human brain ( Betz cells being the largest), with an intricately elaborate dendritic arbor, characterized by a large number of dendritic spines. Purkinje cells are found within the Purkinje layer in the cerebellum. Purkinje cells are aligned like dominos stacked one in front of the other. Their large dendritic ar ...
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Gamma Wave
A gamma wave or gamma rhythm is a pattern of neural oscillation in humans with a frequency between 30 and 100  Hz, the 40 Hz point being of particular interest. Gamma waves with frequencies between 30 and 70 hertz may be classified as low gamma, and those between 70 and 150 hertz as high gamma. Gamma rhythms are correlated with large-scale brain network activity and cognitive phenomena such as working memory, attention, and perceptual grouping, and can be increased in amplitude via meditation or neurostimulation. Altered gamma activity has been observed in many mood and cognitive disorders such as Alzheimer's disease, epilepsy, and schizophrenia. Discovery Gamma waves can be detected by electroencephalography or magnetoencephalography. One of the earliest reports of gamma wave activity was recorded from the visual cortex of awake monkeys. Subsequently, significant research activity has concentrated on gamma activity in visual cortex. Gamma activity has also been detect ...
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