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Orbitofrontal Cortex
The orbitofrontal cortex (OFC) is a prefrontal cortex region in the frontal lobes of the brain which is involved in the cognitive process of decision-making. In non-human primates it consists of the association cortex areas Brodmann area 11, 12 and 13; in humans it consists of Brodmann area 10, 11 and 47. The OFC is functionally related to the ventromedial prefrontal cortex.Phillips, LH., MacPherson, SE. & Della Sala, S. (2002). 'Age, cognition and emotion: the role of anatomical segregation in the frontal lobes: the role of anatomical segregation in the frontal lobes'. in J Grafman (ed.), Handbook of Neuropsychology: the frontal lobes. Elsevier Science, Amsterdam, pp. 73-98. Therefore, the region is distinguished due to the distinct neural connections and the distinct functions it performs.Barbas H, Ghashghaei H, Rempel-Clower N, Xiao D (2002) Anatomic basis of functional specialization in prefrontal cortices in primates. In: Handbook of Neuropsychology (Grafman J, ed), p ...
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Frontal Lobe
The frontal lobe is the largest of the four major lobes of the brain in mammals, and is located at the front of each cerebral hemisphere (in front of the parietal lobe and the temporal lobe). It is parted from the parietal lobe by a Sulcus (neuroanatomy), groove between tissues called the central sulcus and from the temporal lobe by a deeper groove called the lateral sulcus (Sylvian fissure). The most anterior rounded part of the frontal lobe (though not well-defined) is known as the frontal pole, one of the three Cerebral hemisphere#Poles, poles of the cerebrum. The frontal lobe is covered by the frontal cortex. The frontal cortex includes the premotor cortex and the primary motor cortex – parts of the motor cortex. The front part of the frontal cortex is covered by the prefrontal cortex. The nonprimary motor cortex is a functionally defined portion of the frontal lobe. There are four principal Gyrus, gyri in the frontal lobe. The precentral gyrus is directly anterior to the ...
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Orbit (anatomy)
In anatomy Anatomy () is the branch of morphology concerned with the study of the internal structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old scien ..., the orbit is the Body cavity, cavity or socket/hole of the skull in which the eye and Accessory visual structures, its appendages are situated. "Orbit" can refer to the bony socket, or it can also be used to imply the contents. In the adult human, the volume of the orbit is about , of which the eye occupies . The orbital contents comprise the eye, the Orbital fascia, orbital and retrobulbar fascia, extraocular muscles, cranial nerves optic nerve, II, oculomotor nerve, III, trochlear nerve, IV, trigeminal nerve, V, and abducens nerve, VI, blood vessels, fat, the lacrimal gland with its Lacrimal sac, sac and nasolacrimal duct, duct, the eyelids, Medial palpebral ligament, medial and Lateral palpebral raphe, lateral palpebr ...
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Brodmann Area 32
The Brodmann area 32, also known in the human brain as the dorsal anterior cingulate area 32, refers to a subdivision of the cytoarchitecturally defined cingulate cortex. In the human it forms an outer arc around the anterior cingulate gyrus. The cingulate sulcus defines approximately its inner boundary and the superior rostral sulcus (H) its ventral boundary; rostrally it extends almost to the margin of the frontal lobe. Cytoarchitecturally it is bounded internally by the ventral anterior cingulate area 24, externally by medial margins of the agranular frontal area 6, intermediate frontal area 8, granular frontal area 9, frontopolar area 10, and prefrontal area 11-1909. (Brodmann19-09). The dorsal region of the anterior cingulate gyrus is associated with rational thought processes, most notably active during the Stroop task. Guenon In the guenon, Brodmann area 32 is a subdivision of the cytoarchitecturally defined cingulate region of cerebral cortex. This area was ...
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Brodmann Area 25
Brodmann area 25 (BA25) is the subgenual area, area subgenualis or subgenual cingulate area in the cerebral cortex of the brain and delineated based on its cytoarchitectonic characteristics. It is the 25th "Brodmann area" defined by Korbinian Brodmann. BA25 is located in the cingulate region as a narrow band in the caudal portion of the subcallosal area adjacent to the paraterminal gyrus. The posterior parolfactory sulcus separates the paraterminal gyrus from BA25. Rostrally it is bound by the prefrontal area 11 of Brodmann. History Brodmann described this area as it is labeled now in 1909. Originally in 1905, Brodmann labeled the area as part of area 24. In 1909, he divided the area into area 24 and 25. Function This region is extremely rich in serotonin transporters and is considered as a governor for a vast network involving areas like hypothalamus and brain stem, which influences changes in appetite and sleep; the amygdala and insula, which affect the mood and anxie ...
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Brodmann Area 24
Brodmann area 24 is part of the anterior cingulate in the human brain. Human In the human this area is known as ventral anterior cingulate area 24, and it refers to a subdivision of the cytoarchitecturally defined cingulate cortex region of cerebral cortex (area cingularis anterior ventralis). It occupies most of the anterior cingulate gyrus in an arc around the genu of the corpus callosum. Its outer border corresponds approximately to the cingulate sulcus. Cytoarchitecturally it is bounded internally by the pregenual area 33, externally by the dorsal anterior cingulate area 32, and caudally by the ventral posterior cingulate area 23 and the dorsal posterior cingulate area 31. Guenon In the guenon this area is referred to as area 24 of Brodmann-1905. It includes portions of the cingulate gyrus and the frontal lobe. The cortex is thin; it lacks the internal granular layer (IV) so that the densely distributed, plump pyramidal cells of sublayer 3b of the external pyrami ...
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Parahippocampus
The parahippocampal gyrus (or hippocampal gyrus') is a grey matter cortical region, a gyrus of the brain that surrounds the hippocampus and is part of the limbic system. The region plays an important role in memory encoding and retrieval. It has been involved in some cases of hippocampal sclerosis. Asymmetry has been observed in schizophrenia. Structure The anterior part of the gyrus includes the perirhinal and entorhinal cortices. The term parahippocampal cortex is used to refer to an area that encompasses both the posterior parahippocampal gyrus and the medial portion of the fusiform gyrus. Function Scene recognition The parahippocampal place area (PPA) is a sub-region of the parahippocampal cortex that lies medially in the inferior temporo-occipital cortex. PPA plays an important role in the encoding and recognition of environmental scenes (rather than faces). fMRI studies indicate that this region of the brain becomes highly active when human subjects view topographi ...
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Amygdala
The amygdala (; : amygdalae or amygdalas; also '; Latin from Greek language, Greek, , ', 'almond', 'tonsil') is a paired nucleus (neuroanatomy), nuclear complex present in the Cerebral hemisphere, cerebral hemispheres of vertebrates. It is considered part of the limbic system. In Primate, primates, it is located lateral and medial, medially within the temporal lobes. It consists of many nuclei, each made up of further subnuclei. The subdivision most commonly made is into the Basolateral amygdala, basolateral, Central nucleus of the amygdala, central, cortical, and medial nuclei together with the intercalated cells of the amygdala, intercalated cell clusters. The amygdala has a primary role in the processing of memory, decision making, decision-making, and emotions, emotional responses (including fear, anxiety, and aggression). The amygdala was first identified and named by Karl Friedrich Burdach in 1822. Structure Thirteen Nucleus (neuroanatomy), nuclei have been identif ...
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Pyriform Cortex
The piriform cortex, or pyriform cortex, is a region in the brain, part of the rhinencephalon situated in the cerebrum. The function of the piriform cortex relates to the sense of smell. Structure The piriform cortex is part of the rhinencephalon situated in the cerebrum. In human anatomy, the piriform cortex has been described as consisting of the cortical amygdala, uncus, and anterior parahippocampal gyrus. More specifically, the human piriform cortex is located between the insula and the temporal lobe, anteriorly and laterally of the amygdala.Howard, J. D., Plailly, J., Grueschow, M., Haynes, J. D., & Gottfried, J. A. (2009). Odor quality coding and categorization in human posterior piriform cortex. Nature neuroscience, 12(7), 932-938. Supplementary material, p.4 Function The function of the piriform cortex relates to olfaction, which is the perception of smell. This has been particularly shown in humans for the posterior piriform cortex. The piriform cortex in rodents a ...
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Insular Cortex
The insular cortex (also insula and insular lobe) is a portion of the cerebral cortex folded deep within the lateral sulcus (the fissure separating the temporal lobe from the parietal lobe, parietal and frontal lobes) within each brain hemisphere, hemisphere of the mammalian brain. The insulae are believed to be involved in consciousness and play a role in diverse functions usually linked to emotion or the regulation of the body's homeostasis. These functions include compassion, empathy, taste, perception, motor control, self-awareness, cognitive functioning, interpersonal relationships, and awareness of homeostatic emotions such as Hunger (physiology), hunger, pain and fatigue. In relation to these, it is involved in psychopathology. The insular cortex is divided by the central sulcus of the insula, into two parts: the anterior insula and the posterior insula in which more than a dozen field areas have been identified. The cortical area overlying the insula toward the lateral su ...
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Internal Granular Layer (cerebral Cortex)
The internal granular layer of the cerebral cortex, also commonly referred to as the granular layer of the cortex, is the layer IV in the subdivision of the mammalian cerebral cortex into 6 layers. The adjective internal is used in opposition to the external granular layer of the cortex, the term granular refers to the granule cells found here. This layer receives the afferent connections from the thalamus and from other cortical regions and sends connections to the other layers. The line of Gennari (occipital stripe) is also present in this layer. See also * Granular layer * External granular layer (cerebral cortex) The external granular layer of the cerebral cortex is commonly known as layer II. It is different from the internal granular layer of the cerebral cortex (commonly known as layer IV). Layer II is often grouped together with layer III and referr ... Cerebral cortex {{neuroanatomy-stub ...
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Gyrus Rectus
The portion of the inferior frontal lobe immediately adjacent to the longitudinal fissure (and medial to the medial orbital gyrus and olfactory tract) is named the straight gyrus,(or gyrus rectus) and is continuous with the superior frontal gyrus on the medial surface. A specific function for the straight gyrus has not yet been brought to light; however, in males, greater activation of the straight gyrus within the medial orbitofrontal cortex while observing sexually visual pictures has been strongly linked to HSDD (hypoactive sexual desire disorder). Additional images File:Straight gyrus animation small2.gif, Animation. Straight gyrus is depicted as red. File:Straight_gyrus_-_inferior_view.png, Basal surface of cerebrum. Straight gyrus is shown in red. File:Gray743 straight gyrus.png, Coronal section of human brain. Straight gyrus depicted as yellow in center bottom. File:Slide2STE.JPG, Cerebrum. Optic and olfactory nerves.Inferior view. Deep dissection. File:Slide2ZEB.JP ...
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Brodmann Area 14
Brodmann Area 14 is one of Brodmann's subdivisions of the cerebral cortex in the brain. It was defined by Brodmann in the guenon monkey . While Brodmann, writing in 1909, argued that no equivalent structure existed in humans, later work demonstrated that area 14 has a clear homologue in the human ventromedial prefrontal cortex. Anatomy Brodmann areas were defined based on cytoarchitecture rather than function. Area 14 differs most clearly from Brodmann area 13-1905 in that it lacks a distinct internal granular layer (IV). Other differences are a less distinct external granular layer (II), a widening of the relatively cell-free zone of the external pyramidal layer (III); cells in the internal pyramidal layer (V) are denser and rounded; and the cells of the multiform layer (VI) assume a more distinct tangential orientation. Function According to one theory, Area 14 is believed to serve as association cortex for the visceral senses and olfaction along with Area 51. Its an ...
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