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Homarine
Homarine (''N''-methyl picolinic acid betaine) is an organic compound with the chemical formula C7H7NO2. It is commonly found in aquatic organisms from phytoplankton to crustaceans, although it is not found in vertebrates. Biological function Homarine functions as an osmolyte by affecting the ionic strength of the cytosol and thereby maintaining osmotic pressure within the cell. Homarine may also act as a methyl group donor in the biosynthesis of various other ''N''-methylated chemicals, such as glycine betaine and choline. The process of methyl donation converts homarine into picolinic acid and is reversible. Etymology The name of this chemical comes from the initial discovery of the molecule in 1933 in lobster tissue: the word '' homarine'' as an adjective means "of, or relating to, lobsters" (i.e. genus ''Homarus ''Homarus'' is a genus of lobsters, which include the common and commercially significant species ''Homarus americanus'' (the American lobster) and '' Homarus g ...
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Organic Compound
Some chemical authorities define an organic compound as a chemical compound that contains a carbon–hydrogen or carbon–carbon bond; others consider an organic compound to be any chemical compound that contains carbon. For example, carbon-containing compounds such as alkanes (e.g. methane ) and its derivatives are universally considered organic, but many others are sometimes considered inorganic, such as certain compounds of carbon with nitrogen and oxygen (e.g. cyanide ion , hydrogen cyanide , chloroformic acid , carbon dioxide , and carbonate ion ). Due to carbon's ability to catenate (form chains with other carbon atoms), millions of organic compounds are known. The study of the properties, reactions, and syntheses of organic compounds comprise the discipline known as organic chemistry. For historical reasons, a few classes of carbon-containing compounds (e.g., carbonate salts and cyanide salts), along with a few other exceptions (e.g., carbon dioxide, and even ...
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Phytoplankton
Phytoplankton () are the autotrophic (self-feeding) components of the plankton community and a key part of ocean and freshwater Aquatic ecosystem, ecosystems. The name comes from the Greek language, Greek words (), meaning 'plant', and (), meaning 'wanderer' or 'drifter'. Phytoplankton obtain their energy through photosynthesis, as trees and other plants do on land. This means phytoplankton must have light from the sun, so they live in the well-lit surface layers (euphotic zone) of oceans and lakes. In comparison with terrestrial plants, phytoplankton are distributed over a larger surface area, are exposed to less seasonal variation and have markedly faster turnover rates than trees (days versus decades). As a result, phytoplankton respond rapidly on a global scale to climate variations. Phytoplankton form the base of marine and freshwater food webs and are key players in the global carbon cycle. They account for about half of global photosynthetic activity and at least half o ...
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Crustaceans
Crustaceans (from Latin meaning: "those with shells" or "crusted ones") are invertebrate animals that constitute one group of Arthropod, arthropods that are traditionally a part of the subphylum Crustacea (), a large, diverse group of mainly aquatic animal, aquatic arthropods including decapoda, decapods (shrimps, prawns, crabs, lobsters and crayfish), ostracoda, seed shrimp, branchiopoda, branchiopods, argulidae, fish lice, krill, remipedes, isopods, barnacles, copepods, Mysida, opossum shrimps, amphipods and mantis shrimp. The crustacean group can be treated as a subphylum under the clade Mandibulata. It is now well accepted that the Hexapoda, hexapods (insects and entognathans) emerged deep in the Crustacean group, with the completed pan-group referred to as Pancrustacea. The three classes Cephalocarida, Branchiopoda and Remipedia are more closely related to the hexapods than they are to any of the other crustaceans (oligostracans and multicrustaceans). The 67,000 described spec ...
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Osmolyte
Osmolytes are low-molecular-weight organic compounds that influence the properties of biological fluids. Osmolytes are a class of organic molecules that play a significant role in regulating osmotic pressure and maintaining cellular homeostasis in various organisms, particularly in response to environmental stressors. Their primary role is to maintain the integrity of cells by affecting the viscosity, melting point, and ionic strength of the aqueous solution. When a cell swells due to external osmotic pressure, membrane channels open and allow efflux of osmolytes carrying water, restoring normal cell volume. These molecules are involved in counteracting the effects of osmotic stress, which occurs when there are fluctuations in the concentration of solutes (such as ions and sugars) inside and outside cells. Osmolytes help cells adapt to changing osmotic conditions, thereby ensuring their survival and functionality. Osmolytes also interact with the constituents of the cell, e.g., the ...
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Methyl Group
In organic chemistry, a methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms, having chemical formula (whereas normal methane has the formula ). In formulas, the group is often abbreviated as Me. This hydrocarbon group occurs in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, bonded to the rest of the molecule by a single covalent bond (), it can be found on its own in any of three forms: methanide anion (), methylium cation () or methyl radical (). The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed. Methyl cation, anion, and radical Methyl cation The methylium cation () exists in the gas phase, but is otherwise not encountered. Some compounds are considered to be sources of the cation, and this simplification is used pervasively in organic chemistry. For ex ...
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Biosynthesis
Biosynthesis, i.e., chemical synthesis occurring in biological contexts, is a term most often referring to multi-step, enzyme-Catalysis, catalyzed processes where chemical substances absorbed as nutrients (or previously converted through biosynthesis) serve as enzyme substrate (chemistry), substrates, with conversion by the living organism either into simpler or more complex Product (chemistry), products. Examples of biosynthetic pathways include those for the production of amino acids, lipid membrane components, and nucleotides, but also for the production of all classes of biological macromolecules, and of acetyl-coenzyme A, adenosine triphosphate, nicotinamide adenine dinucleotide and other key intermediate and transactional molecules needed for metabolism. Thus, in biosynthesis, any of an array of Chemical compound, compounds, from simple to complex, are converted into other compounds, and so it includes both the catabolism and anabolism (building up and breaking down) of comple ...
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Glycine Betaine
Trimethylglycine is an amino acid derivative with the formula . A colorless, water-soluble solid, it occurs in plants. Trimethylglycine is a zwitterion: the molecule contains both a quaternary ammonium group and a carboxylate group. Trimethylglycine was the first betaine discovered; originally it was simply called betaine because it was discovered in sugar beets (''Beta vulgaris'' subsp. ''vulgaris''). Several other betaines are now known. Medical uses Betaine, sold under the brand name Cystadane, is indicated for the adjunctive treatment of homocystinuria, involving deficiencies or defects in cystathionine beta-synthase (CBS), 5,10-methylene-tetrahydrofolate reductase (MTHFR), or cobalamin cofactor metabolism (cbl). The most common side effect is elevated levels of methionine in the blood. The EU has authorized the health claim that betaine "contributes to normal homocysteine metabolism.". Biological function Biosynthesis In most organisms, glycine betaine is biosynthesiz ...
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Choline
Choline is a cation with the chemical formula . Choline forms various Salt (chemistry), salts, such as choline chloride and choline bitartrate. An essential nutrient for animals, it is a structural component of phospholipids and cell membranes. Choline is used to synthesize acetylcholine, a neurotransmitter involved in muscle control and numerous functions of the nervous system. Choline is involved in early development of the brain, gene expression, cell membrane Signaling peptide receptor, signaling, and brain metabolism. Although humans synthesize choline in the liver, the amount produced naturally is insufficient to meet cellular functions, requiring that some choline be obtained from foods or dietary supplements. Foods rich in choline include meats, poultry, eggs, and other animal-based products, cruciferous vegetables, beans, nuts, and whole grains. Choline is present in breast milk and is commonly added as an food additive, ingredient to baby foods. Chemistry Choline i ...
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Picolinic Acid
Picolinic acid is an organic compound with the formula . It is a derivative of pyridine with a carboxylic acid (COOH) substituent at the 2-position. It is an isomer of nicotinic acid and isonicotinic acid, which have the carboxyl side chain at the 3- and 4-positions, respectively. It is a white solid although impure samples can appear tan. The compound is soluble in water. Production On a commercial scale, picolinic acid is produced by ammoxidation of 2-picoline followed by hydrolysis of the resulting nitrile: : : It is also produced by oxidation of picoline with nitric acid. : In the laboratory, picolinic acid is formed from 2-methylpyridine by oxidation with potassium permanganate (KMnO4). Reactions Hydrogenation of picolinic acid gives piperidine-2-carboxylic acid, a precursor to the drug Mepivacaine. Picolinic acid is a bidentate chelating agent of elements such as chromium, zinc, manganese, copper, iron, and molybdenum in the human body. It is a substrate in the Mitsuno ...
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Lobster
Lobsters are Malacostraca, malacostracans Decapoda, decapod crustaceans of the family (biology), family Nephropidae or its Synonym (taxonomy), synonym Homaridae. They have long bodies with muscular tails and live in crevices or burrows on the sea floor. Three of their five pairs of legs have claws, including the first pair, which are usually much larger than the others. Highly prized as seafood, lobsters are economically important and are often one of the most profitable commodities in the coastal areas they populate. Commercially important species include two species of ''Homarus'' from the northern Atlantic Ocean and Scampi (other), scampi (which look more like a shrimp, or a "mini lobster")—the Northern Hemisphere genus ''Nephrops'' and the Southern Hemisphere genus ''Metanephrops''. Distinction Although several other groups of crustaceans have the word "lobster" in their names, the unqualified term "lobster" generally refers to the clawed lobsters of the fam ...
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Homarus
''Homarus'' is a genus of lobsters, which include the common and commercially significant species ''Homarus americanus'' (the American lobster) and '' Homarus gammarus'' (the European lobster). The Cape lobster, which was formerly in this genus as ''H. capensis'', was moved in 1995 to the new genus ''Homarinus''. Description ''Homarus'' is one of three extant genera of clawed lobsters to show dimorphism between claws – a specialisation into a crushing claw and a cutting claw. The other similar genera are '' Nephrops'', which is much more slender, and has grooves along the claws and the abdomen, and '' Homarinus'', the Cape lobster from South Africa, which is even smaller, and has hairy claws. tp://ftp.fao.org/docrep/fao/009/t0411e/t0411e09.pdf Subfamily Nephropinae Dana, 1852 pp. 51–86 in Holthuis (1991). While analyses of morphology suggest a close relationship between ''Homarinus'' and ''Homarus'', molecular analyses using mitochondrial DNA reveal that they are not ...
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